KR102472257B1 - LINC01798 유전자의 CpG 메틸화 변화를 이용한 대장암, 직장암 또는 대장 선종 진단용 조성물 및 이의 용도 - Google Patents

LINC01798 유전자의 CpG 메틸화 변화를 이용한 대장암, 직장암 또는 대장 선종 진단용 조성물 및 이의 용도 Download PDF

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KR102472257B1
KR102472257B1 KR1020200130539A KR20200130539A KR102472257B1 KR 102472257 B1 KR102472257 B1 KR 102472257B1 KR 1020200130539 A KR1020200130539 A KR 1020200130539A KR 20200130539 A KR20200130539 A KR 20200130539A KR 102472257 B1 KR102472257 B1 KR 102472257B1
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gene
methylation
cancer
colorectal
linc01798
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KR1020200130539A
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Korean (ko)
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KR20220047065A (ko
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조상래
문영호
한진일
이윤영
안준
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주식회사 젠큐릭스
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Priority to KR1020200130539A priority Critical patent/KR102472257B1/ko
Priority to PCT/KR2021/013835 priority patent/WO2022075788A1/fr
Priority to US18/030,515 priority patent/US20230383356A1/en
Publication of KR20220047065A publication Critical patent/KR20220047065A/ko
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020200130539A 2020-10-08 2020-10-08 LINC01798 유전자의 CpG 메틸화 변화를 이용한 대장암, 직장암 또는 대장 선종 진단용 조성물 및 이의 용도 KR102472257B1 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020200130539A KR102472257B1 (ko) 2020-10-08 2020-10-08 LINC01798 유전자의 CpG 메틸화 변화를 이용한 대장암, 직장암 또는 대장 선종 진단용 조성물 및 이의 용도
PCT/KR2021/013835 WO2022075788A1 (fr) 2020-10-08 2021-10-08 Composition pour diagnostiquer un cancer colorectal, un cancer rectal ou un adénome colorectal à l'aide d'un changement de méthylation cpg du gène linc01798, et son utilisation
US18/030,515 US20230383356A1 (en) 2020-10-08 2021-10-08 Composition for diagnosing colorectal cancer, rectal cancer or colorectal adenoma by using cpg methylation change of linc01798 gene, and use thereof

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Application Number Priority Date Filing Date Title
KR1020200130539A KR102472257B1 (ko) 2020-10-08 2020-10-08 LINC01798 유전자의 CpG 메틸화 변화를 이용한 대장암, 직장암 또는 대장 선종 진단용 조성물 및 이의 용도

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KR20220047065A KR20220047065A (ko) 2022-04-15
KR102472257B1 true KR102472257B1 (ko) 2022-11-30

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KR1020200130539A KR102472257B1 (ko) 2020-10-08 2020-10-08 LINC01798 유전자의 CpG 메틸화 변화를 이용한 대장암, 직장암 또는 대장 선종 진단용 조성물 및 이의 용도

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US (1) US20230383356A1 (fr)
KR (1) KR102472257B1 (fr)
WO (1) WO2022075788A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024045170A1 (fr) * 2022-09-02 2024-03-07 深圳华大基因股份有限公司 Combinaison de régions différentiellement méthylées, kit et son utilisation
WO2024045160A1 (fr) * 2022-09-02 2024-03-07 深圳华大基因股份有限公司 Région de méthylation différentielle du gène oplah, kit et utilisation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Cancer Manag Res, 11: 2349-2362 (2019.03.22.)

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US20230383356A1 (en) 2023-11-30
WO2022075788A1 (fr) 2022-04-14
KR20220047065A (ko) 2022-04-15

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