KR102439976B1 - composition - Google Patents

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KR102439976B1
KR102439976B1 KR1020210121714A KR20210121714A KR102439976B1 KR 102439976 B1 KR102439976 B1 KR 102439976B1 KR 1020210121714 A KR1020210121714 A KR 1020210121714A KR 20210121714 A KR20210121714 A KR 20210121714A KR 102439976 B1 KR102439976 B1 KR 102439976B1
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antioxidant
weight
cosmetic composition
melatonin
skin
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오다정이
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(주)닥터솔루션
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • A61K8/9794Liliopsida [monocotyledons]
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    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers
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    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The present invention relates to an antioxidant antibacterial cosmetic composition, and more particularly, to an antioxidant antibacterial cosmetic composition which comprises: a Prunus cerasus fruit extraction made by using a tart cherry, a natural antioxidant that contains nutrients such as melatonin, vitamin A, vitamin C, anthocyanin, folic acid, beta-carotene, and niacin; and a melatonin component that inhibits skin aging, a Tremella fuciformis extract that acts as a moisturizer, a Lactobacillus fermented product, and 1,2-hexanediol, in a solution of 2,3-butanediol, a natural substance made by an eco-friendly method.

Description

천연 항산화 물질인 신양벚나무열매 추출물과 멜라토닌을 함유한 천연 항산화 항균 화장료 조성물{composition}Natural antioxidant antibacterial cosmetic composition containing Shinyang cherry tree fruit extract and melatonin, which are natural antioxidants {composition}

본 발명은 천연 항산화 물질인 신양벚나무열매 추출물과 멜라토닌을 함유한 항산화 항균 화장료 조성물에 관한 것으로서, 더욱 상세하게는 멜라토닌, 비타민A, 비타민C, 안토시아닌, 엽산, 베타카로틴, 니아신 등의 영양성분이 함유되어 있는 천연 항산화 물질인 타트체리를 이용하여 만들어진 신양벚나무열매 추출물과 친환경 공법으로 만들어진 천연물질인 2,3-부탄다이올 용액에 피부 노화를 억제하는 멜라토닌 성분과 보습제 역할을 하는 흰목이버섯추출물, 락토바실러스발효물, 1,2-헥산다이올로 이루어진 천연 항산화 물질인 신양벚나무열매 추출물과 멜라토닌을 함유한 천연 항산화 항균 화장료 조성물에 관한 것이다.The present invention relates to an antioxidant antibacterial cosmetic composition containing a natural antioxidant, Shinyang cherry tree fruit extract and melatonin, and more particularly, melatonin, vitamin A, vitamin C, anthocyanin, folic acid, beta-carotene, and niacin Shinyang cherry tree fruit extract made using tart cherry, a natural antioxidant, and 2,3-butanediol solution, a natural substance made with an eco-friendly method, contains melatonin that inhibits skin aging, and white wood ear mushroom extract that acts as a moisturizer. It relates to a natural antioxidant antibacterial cosmetic composition containing a lactobacillus fermented product, a natural antioxidant consisting of 1,2-hexanediol, a Shinyang cherry tree fruit extract, and melatonin.

멜라토닌은 뇌관에 위치한‘송과선’에서 생성되는 수면조절 호르몬으로 송과선은 피부를 통해 들어오는 빛을 받아들여 생체리듬에 관여하는 호르몬을 형성한다. 이렇게 만들어진 호르몬인 멜라토닌은 밤이 되면 세로토닌으로부터 합성돼 전신으로 분비된다. 이처럼 수면에 지대한 영향을 끼치고 있으며 활성산소의 생성을 막아 세포의 노화를 막는데, 비타민C, E보다도 항산화 효과가 높다. Melatonin is a sleep-regulating hormone produced in the 'pineal gland' located in the brain. At night, the hormone melatonin is synthesized from serotonin and released throughout the body. As such, it has a great effect on sleep and prevents the generation of free radicals to prevent cell aging, and has a higher antioxidant effect than vitamins C and E.

항산화 효과는 피부 노화, 피부탄력 등에 미치는 활성산소를 제거 해준다. 체내로 들어간 산소가 산화 과정에 이용되며 여러 대사과정에 생성되어 신체 내에서 산화작용을 일으켜 노화를 촉진시키고 세포를 손상시키는데 이러한 문제를 항산화 성분인 신양벚나무열매 추출물속에 함유되어 있는 멜라토닌이 막아준다. 그러나 천연 타트체리 열매에서 만들어진 신양벚나무열매 추출물의 경우 멜라토닌을 얻기 위해서는 많은 타트체리가 필요로 하고, 보습력이 부족하기 때문에 본 화장료 조성물에는 멜라토닌 성분을 혼합하였고, 꿀, 프로폴리스, 코코넛, 와인, 김치, 간장, 된장, 토양 등에 존재하는 천연 보습성분인 2,3-부탄다이올과 피부에 영양을 공급해주는 흰목이버섯추출물, 락토바실러스발효물, 1,2-헥산다이올을 보조 성분으로 함께 사용하였고 본 조성물에 대해서 항산화 효능을 확인함으로써 발명을 완성하였다.The antioxidant effect removes free radicals that affect skin aging and skin elasticity. Oxygen that enters the body is used for the oxidation process, and it is generated in various metabolic processes, causing oxidation in the body to accelerate aging and damage cells. However, in the case of Shinyang cherry tree fruit extract made from natural tart cherry fruit, a lot of tart cherries are required to obtain melatonin and lack of moisturizing power. , 2,3-butanediol, a natural moisturizing ingredient present in soy sauce, soybean paste, and soil, as well as white wood ear mushroom extract, lactobacillus fermented product, and 1,2-hexanediol that provide nutrition to the skin are used together as auxiliary ingredients. and completed the invention by confirming the antioxidant efficacy of the composition.

일반적으로 화장품의 항산화제라 함은 산화작용으로 손상된 피부 기능과 구조가 파괴되고 소진되는 현상을 상당 정도 감소시키거나 예방하는 능력을 갖고 있고 자외선 노출로 인해 손상된 피부를 회복시켜주는 것을 목적으로 한다.In general, antioxidants in cosmetics have the ability to significantly reduce or prevent the destruction and exhaustion of skin functions and structures damaged by oxidation, and to restore skin damaged by UV exposure.

항산화 화장품은 일반적으로 피부를 정돈, 보호용의 기초 항산화 화장품, 베이스, 포인트, 손발톱용 메이크업 항산화 화장품 및 세정용, 선케어, 선테닝 등의 바디 항산화화장품 및 샴푸-전(pre-shampoo) 조성물, 샴푸, 린스, 트리트먼트, 왁스, 스프레이, 무스, 헤어로션, 에센스, 헤어크림, 영구 염모제, 일시 염모제, 펌제 등의 모발에 사용할 수 있는 화장품 제제들을 모두 포함할 수 있다.Antioxidant cosmetics generally include basic antioxidant cosmetics for skin conditioning and protection, makeup antioxidant cosmetics for base, point, and nails, body antioxidant cosmetics for cleansing, sun care, sun-tanning, and pre-shampoo compositions, shampoos, It may include all cosmetic preparations that can be used for hair, such as conditioner, treatment, wax, spray, mousse, hair lotion, essence, hair cream, permanent hair dye, temporary hair dye, and perm.

항산화 화장품 원료 및 약제 성분으로 피부 및 모발에 사용하는 경우 처리 후에 다음 세정시까지 일시적인 효과만을 제공 할 뿐 세정 이후에는 재처리 해줘야 하는 번거로움이 항상 존재하고 있다.When used on skin and hair as an antioxidant cosmetic raw material and pharmaceutical ingredient, it provides only a temporary effect until the next washing after treatment, and there is always the inconvenience of having to reprocess after washing.

피부의 노화에 활성산소(Reactive oxygen species, ROS)가 관련되어 있다는 것은 수많은 연구에 의해 잘 알려진 사실이다. 노화의 활성 산소설은 1956년 Harman에 의해 제안되었으며 정상적인 대사과정에서 부수적으로 생성되는 여러 가지 활성산소들에 의하여 생체구성 성분들이 산화적 손상을 받게 되고 이러한 손상들이 축적되어 노화와 죽음에 이르게 된다는 것이다. 활성 산소들에 의한 손상들은 생체가 가지고 있는 방어능력으로 대처되고 있지만 방어가 100% 완전치 못하므로 일부의 활성산소에 의한 유해작용을 받게 된다. 유해작용은 천천히 경우에 따라서 수년 내지는 일생을 통하여 만성적으로 일어나 누적되어 피부의 세포나 조직의 기능을 저하시키고 이것이 곧 질병 및 노화의 원인이 된다.It is a well-known fact by numerous studies that reactive oxygen species (ROS) are involved in skin aging. The active oxygen theory of aging was proposed by Harman in 1956, and biocomponents receive oxidative damage by various free radicals incidentally generated during normal metabolic processes, and these damages accumulate and lead to aging and death. . Damage caused by active oxygen is being dealt with with the defense ability of the living body, but because the defense is not 100% complete, some of the free radicals receive harmful effects. Harmful effects occur slowly, in some cases, chronically over several years or throughout life, and accumulate to lower the function of cells or tissues of the skin, which in turn causes diseases and aging.

염증의 발현은 체내의 항상성을 유지하기 위한 일련의 반응이지만 임상적으로는 발적, 종창, 발열, 동통 및 기능 장애 등이 나타날 수 있다. 조직학적으로 염증 부위를 관찰하면 세포의 괴사, 모세혈관의 확장, 부종과 동시에 호중구, 단구를 주체로 하는 염증성 세포의 침윤을 볼 수 있다. 이와 같은 현상은 동시에 일어나는 것이 아니고 일련의 순서를 갖고 출현하는 것이다. 이 과정에 작용하는 많은 화학매개체(화학적 매개물질)와 그 작용이 계속 알려지고 있다. Although the expression of inflammation is a series of reactions to maintain homeostasis in the body, clinically, redness, swelling, fever, pain, and dysfunction may appear. When observing the inflammatory site histologically, cell necrosis, expansion of capillaries, and edema, as well as infiltration of inflammatory cells mainly composed of neutrophils and monocytes can be seen. These phenomena do not occur simultaneously, but appear in a sequence. Many chemical mediators (chemical mediators) acting in this process and their actions continue to be known.

염증의 과정을 시간적으로 보면 혈류 및 혈관크기의 변동에 의한 혈역동학적 변동(Hemodynamic changes)과 염증세포의 삼출, 또한 결합조직의 증식의 3단계로 나누어 진행된다. ROS와 연관되어 연구가 되고 있는 부분은 혈역동학적 변동으로 간단하게 정리하면 다음과 같다.The process of inflammation is divided into three stages: hemodynamic changes due to fluctuations in blood flow and blood vessel size, exudation of inflammatory cells, and proliferation of connective tissue. The part that is being studied in relation to ROS is hemodynamic fluctuations, which can be briefly summarized as follows.

염증시에는 혈소판 활성물질(platelet activating factor, PAF)이 분비되어 혈관의 투과성이 증가되며 산화질소(nitric oxide) 합성이 증가되며 혈관이 확장되고 부착분자들이 발현되어 백혈구의 부착 및 이동에 관여한다. 급성 염증시에는 내피세포의 표면의 성질이 변화한다. 일련의 반응과 ROS를 연관시킨 연구를 많이 하고 있는 추세이다.During inflammation, platelet activating factor (PAF) is secreted to increase vascular permeability, nitric oxide synthesis is increased, blood vessels are dilated, and adhesion molecules are expressed, which are involved in the adhesion and movement of leukocytes. During acute inflammation, the surface properties of endothelial cells change. There is a tendency to do a lot of research related to a series of reactions and ROS.

생체에서 항산화는 필수적이라고 할 수 있는데 음식이나 보충제로 항산화제를 섭취할 경우 피부까지 도달하는 것은 쉽지 않다. 피부는 인체의 최외각을 감싸고 있어 외부 환경과 자외선 등의 유해 요인에 늘 직접 맞닿아 있으면서도 생명과 직결되지는 않는 말초 기관이기 때문에 체내에 비타민이나 항산화제가 부족하게 되면 가장 먼저 피부에 결핍이 오기 쉽다. 인체의 입장에서 오장육부 등 생존에 중요한 장기에 먼저 필요한 성분을 공급한 후 남는 것을 피부에 보내주게 된다. 그러므로 피부에도 항산화력을 부여하는 것이 필요하다고 할 수 있다.It can be said that antioxidants are essential in the living body, but it is not easy to reach the skin if you take antioxidants through food or supplements. Since the skin is a peripheral organ that is always in direct contact with the external environment and harmful factors such as UV rays as it wraps around the outermost part of the human body, it is not directly related to life. . From the point of view of the human body, the necessary ingredients are first supplied to organs important for survival, such as the organs and organs, and then the remainder is sent to the skin. Therefore, it can be said that it is necessary to give antioxidant power to the skin as well.

피부에서의 항산화 효과를 구현하게 된다면 화장품에 대한 피부 항산화에 대한 고객들의 요구를 강하게 충족시키게 되어 피부 노화에 대한 다양한 효능인 항산화, 피부결 및 탄력 개선 효능 부분에서 큰 인기를 끌게 될 것이다.If the antioxidant effect on the skin is realized, the customer's demand for skin antioxidant for cosmetics will be strongly met, and it will become popular in the antioxidant, skin texture and elasticity improvement, which are various effects on skin aging.

본 발명은 종래의 문제점을 개선한 것으로서 항산화를 이용하여 보다 피부 노화를 막는데 도움을 주는 화장료 조성물을 제공하는 것을 목적으로 한다.An object of the present invention is to provide a cosmetic composition that helps to prevent skin aging by using antioxidants as an improvement of the conventional problems.

또한, 본 발명은 멜라토닌이 가지고 있는 효능 뿐만 아니라 보조 역할을 하는 천연 보습제 성분을 적용함으로써 멜라토닌의 피부노화 예방 및 보습역할을 동시에 함께 할 수 있는 최적의 구성비 선정을 제공하는 것이다.In addition, the present invention provides not only the efficacy of melatonin, but also the selection of the optimal composition ratio that can simultaneously prevent skin aging and play a moisturizing role of melatonin by applying a natural moisturizing agent that plays an auxiliary role.

상기와 같은 목적을 달성하기 위해 본 발명은 신양벚나무열매 추출물, 2,3-부탄다이올, 멜라토닌, 흰목이버섯추출물, 락토바실러스발효물, 1,2-헥산다이올을 함유하는 항산화, 항균력 화장료 조성물을 제공한다. In order to achieve the above object, the present invention provides a cosmetic with antioxidant and antibacterial power containing Shinyang cherry tree fruit extract, 2,3-butanediol, melatonin, white wood ear mushroom extract, lactobacillus fermented product, and 1,2-hexanediol. A composition is provided.

본 발명은 천연 항산화물질인 신양벚나무열매 추출물과 멜라토닌을 함유시킨 항산화, 항균력 화장료 조성물이며, 항산화 효능과 항균력이 있는 성분으로 다양한 화장품 제형에 적용이 가능하다. 본 발명은 수용성으로 개발되어 제품의 발림성까지 개선 가능하다. The present invention is an antioxidant and antibacterial cosmetic composition containing natural antioxidants Shinyang cherry tree fruit extract and melatonin. The present invention is developed to be water-soluble, so it is possible to improve the spreadability of the product.

본 발명에 따른 항산화 효과는 활성산소의 피부 세포 및 조직 손상을 보호하며 피부와 신체 노화를 발생시키는 피부의 활성산소 발생을 억제하고 예방해 주는 역할을 하며, 피부에 적용 경우 우수한 항산화 효과를 제공함으로써 주름과 피부결을 개선시키고 피부 탄력을 증진시키며 자외선 및 스트레스에 의해 유발되는 피부 세포 손상을 막아주는 효과가 탁월하다.The antioxidant effect according to the present invention protects the skin cells and tissue damage of free radicals, and serves to inhibit and prevent the generation of active oxygen in the skin that causes skin and body aging, and provides an excellent antioxidant effect when applied to the skin to prevent wrinkles. It is effective in improving skin texture and skin elasticity, preventing damage to skin cells caused by UV rays and stress.

본 발명에 따른 항균효과는 여드름 원인균인 포도상구균 (Staphylococcus epidermidis), 프로피오니박테리움 아크네스 (Cutibacterium acnes), 피부발진과 아토피부염을 악화시키는 황색포도상구균(Staphylococcus aureu), 무좀균인 적색 백선균 (Trichophyton rubrum)에 대해서 효과적이다.The antibacterial effect according to the present invention is the bacterium that causes acne, Staphylococcus epidermidis, Propionibacterium acnes, Staphylococcus aureu, which exacerbates skin rashes and atodermatitis, and Trichophyton, the athlete's foot bacteria. rubrum) is effective.

도 1은 본 발명의 화장료 조성물에 대한 항균실험을 나타낸 사진.
도 2는 본 발명의 화장료 조성물에 대한 항균실험을 나타낸 사진.
1 is a photograph showing an antibacterial test for the cosmetic composition of the present invention.
Figure 2 is a photograph showing an antibacterial test for the cosmetic composition of the present invention.

본 발명은 멜라토닌, 비타민A, 비타민C, 안토시아닌, 엽산, 베타카로틴, 니아신의 영양성분이 함유되어 있는 천연 항산화 물질인 타트체리를 이용하여 만들어진 신양벚나무열매 추출물과 친환경 공법으로 만들어진 천연물질인 2,3-부탄다이올 용액에 피부 노화를 억제하는 멜라토닌 성분과 보습제 역할을 하는 흰목이버섯추출물, 락토바실러스발효물, 1,2-헥산다이올로 이루어진 천연 항산화 물질인 신양벚나무열매 추출물과 멜라토닌을 함유한 천연 항산화 항균 화장료 조성물에 관한 것이다.The present invention provides a natural antioxidant made using tart cherry, a natural antioxidant containing melatonin, vitamin A, vitamin C, anthocyanin, folic acid, beta-carotene, and niacin, and a natural substance made by an eco-friendly method 2, 3-butanediol solution contains melatonin, a component of melatonin that inhibits skin aging, and melatonin It relates to a natural antioxidant antibacterial cosmetic composition.

본 발명은 항산화 항균 화장료 조성물에 있어서 신양벚나무열매 추출물 70∼80 중량부, 2,3-부탄다이올 3∼6 중량부, 멜라토닌 0.01 ∼1 중량부, 흰목이버섯추출물 0.01∼1 중량부, 락토바실러스발효물 0.01∼1 중량부, 1,2-헥산다이올 2∼20 중량부를 함유하는 항산화 항균 화장료 조성물에 관한 것이다.The present invention relates to an antioxidant antibacterial cosmetic composition, 70 to 80 parts by weight of Shinyang cherry tree fruit extract, 3 to 6 parts by weight of 2,3-butanediol, 0.01 to 1 part by weight of melatonin, 0.01 to 1 part by weight of white wood ear mushroom extract, and lactose. It relates to an antioxidant antibacterial cosmetic composition containing 0.01 to 1 parts by weight of fermented bacillus and 2 to 20 parts by weight of 1,2-hexanediol.

본 발명의 항산화 항균 화장료 조성물은 항산화 항균 조성물 전체 대비 1~5 중량부의 알로에 바바덴시스잎 추출물과 항산화 항균 조성물 전체 대비 1~5 중량부의 시트러스 아우랜티움 덜시스 오일을 추가 혼합한 것을 특징으로 한다.The antioxidant antibacterial cosmetic composition of the present invention is characterized by additionally mixing 1 to 5 parts by weight of Aloe barbadensis leaf extract and 1 to 5 parts by weight of Citrus Aurantium dulcis oil compared to the total amount of the antioxidant antibacterial composition. .

본 발명의 항산화 항균 화장료 조성물은 아토피피부염 감염 원인균인 황색포도상구균과 피부 농양의 주원인균인 포도상구균의 항균력 효능이 강화된 것을 특징으로 한다.The antioxidant antibacterial cosmetic composition of the present invention is characterized in that the antibacterial effect of Staphylococcus aureus, the causative agent of atopic dermatitis infection, and Staphylococcus aureus, the main causative agent of skin abscesses, is enhanced.

본 발명의 화장료 조성물은 베타카로틴, 비타민A, 파이토캐미컬이 함유되어 있는 타트체리로 만들어진 신양벚나무열매 추출물 함량이 높아 항산화 활성증대, 아토피피부염 감염 원인균인 황색포도상구균과 피부 농양의 주원인균인 포도상구균의 항균력 효능 등 기능성 강화된 항산화, 항균력 화장료 조성물을 제공할 수 있다.The cosmetic composition of the present invention has a high content of Shinyang cherry tree fruit extract made from tart cherries containing beta-carotene, vitamin A, and phytochemicals, thereby increasing antioxidant activity, Staphylococcus aureus, the causative agent of atopic dermatitis, and Staphylococcus aureus, the main causative agent of skin abscesses. It is possible to provide a cosmetic composition with enhanced antioxidant and antibacterial power, such as antibacterial effect of cocci.

본 발명의 실시예에 따른 화장료 조성물은 신양벚나무열매 추출물 70 내지 80 중량부가 사용되는 것을 특징으로 하며 2,3-부탄다이올은 화장료 조성물 총중량에 대해서 3 내지 6중량%로 함유되는 것을 특징으로 한다. 본 발명에 따른 화장료 조성물은 신양벚나무열매 추출물에서 항산화 효능과 항균력 효과를 가지게 된다.The cosmetic composition according to an embodiment of the present invention is characterized in that 70 to 80 parts by weight of the Shinyang cherry tree fruit extract is used, and 2,3-butanediol is contained in an amount of 3 to 6% by weight based on the total weight of the cosmetic composition . The cosmetic composition according to the present invention has an antioxidant effect and an antibacterial effect from the Shinyang cherry tree fruit extract.

본 발명의 화장료 조성물은 멜라토닌, 흰목이버섯추출물, 락토바실러스발효물, 1,2-헥산다이올로 이루어지게 된다.The cosmetic composition of the present invention is composed of melatonin, white wood ear mushroom extract, lactobacillus fermented product, and 1,2-hexanediol.

본 발명에서 사용되는 알로에 바바덴시스잎 추출물은 항산화 항균 조성물 전체 대비 1~5 중량부가 바람직하고, 시트러스 아우랜티움 덜시스 오일은 항산화 항균 조성물 전체 대비 1~5 중량부를 사용하는 것이 바람직하고, 혼합되는 알로에 바바덴시스잎 추출물과 시트러스 아우랜티움 덜시스 오일은 안전하고 안정한 화장품용 천연방부제이며, 항산화 효과를 증가시킨다.The Aloe barbadensis leaf extract used in the present invention is preferably 1 to 5 parts by weight relative to the total antioxidant antibacterial composition, and the Citrus Aurantium dulcis oil is preferably 1 to 5 parts by weight relative to the total antioxidant antibacterial composition, mixed Aloe barbadensis leaf extract and Citrus Aurantium dulcis oil are safe and stable natural preservatives for cosmetics and increase antioxidant effect.

본 발명에서 사용되는 화장품용 천연방부제는 시트러스 아우랜티움 덜시스오일과 알로에 바바덴시스 잎추출물을 조합하여 뛰어난 항산화 효과와 방부 효과를 갖는 방부제 조성을 얻어낼 수 있다. The natural preservative for cosmetics used in the present invention is a combination of Citrus Aurantium dulcis oil and Aloe barbadensis leaf extract to obtain a preservative composition having excellent antioxidant and antiseptic effects.

본 발명에서 사용되는 백합과 식물인 알로에는 고온 건조한 기후에서 잘 자라는 선인장 식물이며 건강기능 식품과 화장품 원료로 많이 쓰이는데 인디언 호피부족이 알로에를 하늘의 기적이라고 부를 만큼 특별한 성분이 많이 담겨있다.Aloe, a lily plant used in the present invention, is a cactus plant that grows well in hot and dry climates and is widely used as a raw material for health functional foods and cosmetics.

본 발명에서 사용되는 알로에는 구성하는 물질이 무려 160여 가지가 되고 과육을 많이 포함한 알로에는 잎이 뽀족한 것이 특징이며 잎을 자르면 투명한 젤이 나오고 이것이 화장품의 활성성분으로 사용되는 알로에베라의 원료이다. 본 발명에서 사용되는 추출된 알로에 수액은 쉽게 변질될 정도로 불안정하여 신속한 가공이 알로에의 좋은 성분을 얼마나 담을 수 있는지 좌우하다 보니 일부에서는 알로에 성분을 소량만 배합해 사용한다.The aloe used in the present invention consists of about 160 substances, and the aloe containing a lot of flesh is characterized by sharp leaves. . The extracted aloe sap used in the present invention is unstable enough to deteriorate easily, so rapid processing determines how much good aloe can contain.

본 발명에서 사용되는 시트러스오일과의 조합에 의한 방부 기능외에 알로에의 대표적인 효능은 피부를 탄력 있게 가꾸고 상처를 아물게 하는 치료 효과이다. 본 발명에서 사용되는 알로에는 탁월한 보습 효과와 피부 자극을 완화해 주며, 거칠고 손상된 피부를 부드럽게 관리해주는데 효과적이고 직사광선에 노출된 피부를 진정시켜주며 보호해주기 때문에 여름철 수분크림이나 진정크림으로 많이 쓰이며, 보습 크림과 자외선 차단 제품에 많이 사용되고 있다.In addition to the antiseptic function by the combination with the citrus oil used in the present invention, the representative effect of aloe is the therapeutic effect of making the skin elastic and healing wounds. Aloe used in the present invention has an excellent moisturizing effect and relieves skin irritation, is effective in gently managing rough and damaged skin, and soothes and protects skin exposed to direct sunlight. It is widely used in creams and sunscreen products.

본 발명의 항산화 항균 조성물은 아토피피부염 감염 원인균인 황색포도상구균과 피부 농양의 주원인균인 포도상구균의 항균력 효능이 강화된 것에 사용되는 것이 바람직하다.The antioxidant antibacterial composition of the present invention is preferably used for the enhanced antibacterial effect of Staphylococcus aureus, the causative agent of atopic dermatitis, and Staphylococcus aureus, the main causative agent of skin abscesses.

이하, 본 발명에 따른 실시예를 제시하여 설명한다. 실시예에 대한 항산화 효능과 아토피피부염 감염 원인균인 황색포도상구균과 피부 농양의 주원인균인 포도상구균을 억제하는 화장료 조성물은 다음과 같은 실시예로 진행되었다.Hereinafter, an embodiment according to the present invention will be presented and described. The cosmetic composition for inhibiting the antioxidant efficacy for Examples and Staphylococcus aureus, the causative agent of atopic dermatitis infection, and Staphylococcus aureus, the main causative agent of skin abscesses, was carried out in the following examples.

실시예 1: 화장료 조성물의 제조Example 1: Preparation of a cosmetic composition

신양벚나무열매 추출물 80g, 2,3-부탄다이올 6g, 멜라토닌 1g, 흰목이버섯추출물 1g, 락토바실러스발효물 1g, 1,2-헥산다이올 20g으로 이루어진 것을 수상성분은 원료를 평량한 후 패들을 이용하여 균일하게 분산하여 80℃ 용해하여 수상을 준비한다. 유상성분 원료들을 평량한 후 균일하게 혼합하여 유상을 준비한다. 유상에는 오일과 칼라, 실리카 등을 첨가한다. 다음 공정으로 유상을 80℃까지 가온하고 같은 온도인 수상을 서서히 혼합하면서 50%까지는 2000rpm 중속으로 혼합하고 나머지 100%까지는 2500rpm으로 균질하게 유화시켜셔 화장료 조성물을 제조한다.It consists of 80 g of Shinyang cherry tree fruit extract, 6 g of 2,3-butanediol, 1 g of melatonin, 1 g of white wood ear mushroom extract, 1 g of lactobacillus ferment, and 20 g of 1,2-hexanediol. The aqueous phase is prepared by dissolving it uniformly at 80 ° C. After weighing the raw materials for the oil phase, uniformly mix to prepare the oil phase. Oil, color and silica are added to the oil phase. In the next step, the cosmetic composition is prepared by heating the oil phase to 80° C., mixing the aqueous phase at the same temperature slowly, mixing at a medium speed of 2000 rpm up to 50%, and homogeneously emulsifying the remaining 100% at 2500 rpm.

실시예 2: 화장료 조성물의 제조Example 2: Preparation of a cosmetic composition

신양벚나무열매 추출물 80g, 2,3-부탄다이올 6g, 멜라토닌 1g, 흰목이버섯추출물 1g, 락토바실러스발효물 1g, 1,2-헥산다이올 20g, 알로에 바바덴시스잎 추출물 5g 및 시트러스 아우랜티움 덜시스 오일 5g으로 이루어진 것을 수상성분은 원료를 평량한 후 패들을 이용하여 균일하게 분산하여 80℃ 용해하여 수상을 준비한다. 유상성분 원료들을 평량한 후 균일하게 혼합하여 유상을 준비한다. 유상에는 오일과 칼라, 실리카 등을 첨가한다. 다음 공정으로 유상을 80℃까지 가온하고 같은 온도인 수상을 서서히 혼합하면서 50%까지는 2000rpm 중속으로 혼합하고 나머지 100%까지는 2500rpm으로 균질하게 유화시켜셔 화장료 조성물을 제조한다.Shinyang cherry tree fruit extract 80g, 2,3-butanediol 6g, melatonin 1g, white wood ear mushroom extract 1g, lactobacillus fermented product 1g, 1,2-hexanediol 20g, aloe barbadensis leaf extract 5g and citrus auran After weighing the raw materials for the aqueous phase component consisting of 5 g of Tium dulcis oil, uniformly disperse it using a paddle and dissolve it at 80° C. to prepare the aqueous phase. After weighing the raw materials for the oil phase, uniformly mix to prepare the oil phase. Oil, color and silica are added to the oil phase. In the next step, the cosmetic composition is prepared by heating the oil phase to 80° C., mixing the aqueous phase at the same temperature slowly, mixing at a medium speed of 2000 rpm up to 50%, and homogeneously emulsifying the remaining 100% at 2500 rpm.

본 발명의 실시예에 따른 화장료 조성물은 신양벚나무열매 추출물 70 내지 80 중량부가 사용되는 것을 특징으로 하며 2,3-부탄다이올은 화장료 조성물 총중량에 대해서 3 내지 6 중량부로 함유되는 것을 특징으로 한다. 본 발명에 따른 화장료 조성물은 신양벚나무열매 추출물에서 항산화 효능과 항균력 효과를 가지게 되며, 멜라토닌, 흰목이버섯추출물, 락토바실러스발효물, 1,2-헥산다이올로 이루어지게 된다.The cosmetic composition according to an embodiment of the present invention is characterized in that 70 to 80 parts by weight of the Shinyang cherry tree fruit extract is used, and 2,3-butanediol is contained in 3 to 6 parts by weight based on the total weight of the cosmetic composition. The cosmetic composition according to the present invention has antioxidant and antibacterial effects from the Shinyang cherry tree fruit extract, and is composed of melatonin, white oyster mushroom extract, lactobacillus fermented product, and 1,2-hexanediol.

실험예 1: 항산화시험결과 Experimental Example 1: Antioxidant test result

실시예 1에 의하여 제조된 화장료 조성물을 사용하여 항산화시험을 실행하였다.An antioxidant test was performed using the cosmetic composition prepared according to Example 1.

Figure 112021105717682-pat00001
Figure 112021105717682-pat00001

이하 상기 조성물에 대한 항산화 시험은 DPPH를 혼합하여 30분간 반응 후 517nm에서 흡광도 측정을 하였다.Hereinafter, for the antioxidant test for the composition, absorbance was measured at 517 nm after reacting for 30 minutes by mixing DPPH.

<항산화 시험결과><Antioxidant test result>

Figure 112021105717682-pat00002
Figure 112021105717682-pat00002

실험예 2: 항균시험결과Experimental Example 2: Antibacterial test result

실시예 1에 의하여 제조된 화장료 조성물을 사용하여 포도상구균 (Staphylococcus epidermidis), 프로피오니박테리움 아크네스 (Cutibacterium acnes), 황색포도상구균(Staphylococcus aureu) 및 적색 백선균 (Trichophyton rubrum)으로 항균 실험을 실행하였다.Using the cosmetic composition prepared according to Example 1, an antibacterial experiment was performed with Staphylococcus epidermidis, Propionibacterium acnes, Staphylococcus aureu and Trichophyton rubrum. .

<항균력 시험결과><Antibacterial power test result>

Figure 112021105717682-pat00003
Figure 112021105717682-pat00003

Figure 112021105717682-pat00004
Figure 112021105717682-pat00004

실험예 3: 항산화시험결과 Experimental Example 3: Antioxidant test result

실시예 2에 의하여 제조된 화장료 조성물을 사용하여 항산화시험을 실행하였다. 항산화시험결과는 실시예 1을 사용한 화장료 조성물보다 2 내지 5% 정도 우수한 항산화 결과가 나왔다.An antioxidant test was performed using the cosmetic composition prepared according to Example 2. The antioxidant test results showed excellent antioxidant results by 2 to 5% compared to the cosmetic composition using Example 1.

100: 대조구와 실험구100: control and experimental groups

Claims (3)

신양벚나무열매 추출물 70∼80 중량부, 2,3-부탄다이올 3∼6 중량부, 멜라토닌 0.01 ∼1 중량부, 흰목이버섯추출물 0.01∼1 중량부, 락토바실러스발효물 0.01∼1 중량부, 1,2-헥산다이올 2∼20 중량부를 포함한 것이며,
1~5 중량부의 알로에 바바덴시스잎 추출물 및 1~5 중량부의 시트러스 아우랜티움 덜시스 오일을 더 포함한 것이며,
아토피피부염 감염 원인균인 황색포도상구균과 피부 농양의 주원인균인 포도상구균의 항균력 효능이 강화된 것을 특징으로 하는 신양벚나무열매 추출물과 멜라토닌을 함유한 천연 항산화 항균 화장료 조성물.

70-80 parts by weight of Shinyang cherry tree fruit extract, 3-6 parts by weight of 2,3-butanediol, 0.01-1 part by weight of melatonin, 0.01-1 part by weight of white wood ear mushroom extract, 0.01-1 part by weight of lactobacillus fermented product, It contains 2 to 20 parts by weight of 1,2-hexanediol,
1 to 5 parts by weight of Aloe barbadensis leaf extract and 1 to 5 parts by weight of Citrus Aurantium Dulcis oil,
A natural antioxidant antibacterial cosmetic composition containing an extract of Shinyang cherry tree fruit and melatonin, characterized in that the antibacterial effect of Staphylococcus aureus, the causative agent of atopic dermatitis infection, and Staphylococcus aureus, the main causative agent of skin abscesses, is enhanced.

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Citations (4)

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Publication number Priority date Publication date Assignee Title
KR20180056400A (en) * 2016-11-18 2018-05-28 지에스칼텍스 주식회사 Cosmetic composition including 2,3-butanediol
KR101882736B1 (en) * 2017-07-10 2018-07-27 김삼 Composition for skin protection comprising melatonin, vitamin C and pycnogenol as effective ingredient
KR102085492B1 (en) * 2019-11-01 2020-03-05 대봉엘에스 주식회사 Composition comprising the extract of tremella fuciformis culture medium
KR20200064786A (en) * 2018-11-29 2020-06-08 (주)한국생명과학연구소 Cosmetic composition containing active materials of Aloin

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Publication number Priority date Publication date Assignee Title
KR20180056400A (en) * 2016-11-18 2018-05-28 지에스칼텍스 주식회사 Cosmetic composition including 2,3-butanediol
KR101882736B1 (en) * 2017-07-10 2018-07-27 김삼 Composition for skin protection comprising melatonin, vitamin C and pycnogenol as effective ingredient
KR20200064786A (en) * 2018-11-29 2020-06-08 (주)한국생명과학연구소 Cosmetic composition containing active materials of Aloin
KR102085492B1 (en) * 2019-11-01 2020-03-05 대봉엘에스 주식회사 Composition comprising the extract of tremella fuciformis culture medium

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