KR102392441B1 - 만성 신장 질환 환자의 유해한 심장 사건과 관련된 사망률 및 이환률 감소를 위한 시트르산 제2철 - Google Patents

만성 신장 질환 환자의 유해한 심장 사건과 관련된 사망률 및 이환률 감소를 위한 시트르산 제2철 Download PDF

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Publication number
KR102392441B1
KR102392441B1 KR1020167014000A KR20167014000A KR102392441B1 KR 102392441 B1 KR102392441 B1 KR 102392441B1 KR 1020167014000 A KR1020167014000 A KR 1020167014000A KR 20167014000 A KR20167014000 A KR 20167014000A KR 102392441 B1 KR102392441 B1 KR 102392441B1
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South Korea
Prior art keywords
ferric citrate
iron
patient
ckd
provides
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Korean (ko)
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KR20160096597A (ko
Inventor
엔리케 포라도수
론 벤처
제임스 에프. 3세 올리비에로
Original Assignee
케릭스 바이오파마슈티컬스 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020167014000A 2013-11-04 2014-11-03 만성 신장 질환 환자의 유해한 심장 사건과 관련된 사망률 및 이환률 감소를 위한 시트르산 제2철 Active KR102392441B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361899866P 2013-11-04 2013-11-04
US61/899,866 2013-11-04
PCT/US2014/063643 WO2015066593A1 (en) 2013-11-04 2014-11-03 Ferric citrate for reducing cardiac failure in chronic kidney disease patients

Publications (2)

Publication Number Publication Date
KR20160096597A KR20160096597A (ko) 2016-08-16
KR102392441B1 true KR102392441B1 (ko) 2022-05-02

Family

ID=53005244

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167014000A Active KR102392441B1 (ko) 2013-11-04 2014-11-03 만성 신장 질환 환자의 유해한 심장 사건과 관련된 사망률 및 이환률 감소를 위한 시트르산 제2철

Country Status (15)

Country Link
US (3) US20160256486A1 (cg-RX-API-DMAC10.html)
EP (2) EP3065734A4 (cg-RX-API-DMAC10.html)
JP (3) JP2016535780A (cg-RX-API-DMAC10.html)
KR (1) KR102392441B1 (cg-RX-API-DMAC10.html)
CN (1) CN105873583A (cg-RX-API-DMAC10.html)
AU (1) AU2014341975A1 (cg-RX-API-DMAC10.html)
BR (1) BR112016009901A8 (cg-RX-API-DMAC10.html)
CA (1) CA2928200A1 (cg-RX-API-DMAC10.html)
EA (1) EA201690926A1 (cg-RX-API-DMAC10.html)
HK (1) HK1223031A1 (cg-RX-API-DMAC10.html)
IL (1) IL245317A0 (cg-RX-API-DMAC10.html)
MX (1) MX2016005734A (cg-RX-API-DMAC10.html)
SG (1) SG11201603091QA (cg-RX-API-DMAC10.html)
TW (2) TWI744215B (cg-RX-API-DMAC10.html)
WO (1) WO2015066593A1 (cg-RX-API-DMAC10.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20120046753A (ko) 2009-07-21 2012-05-10 케릭스 바이오파마슈티컬스 인코포레이티드 구연산철 투여형태
KR102633597B1 (ko) 2013-06-05 2024-02-06 트리시다, 인크. 경구 투여를 위한 양성자-결합 중합체
EP3157516A4 (en) 2014-06-22 2017-12-13 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
IL322207A (en) 2014-12-10 2025-09-01 Tricida Inc Proton-binding polymers for oral administration
IL262660B2 (en) 2016-05-06 2024-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
MX2021004640A (es) 2018-10-29 2021-05-28 Pharmacosmos Holding As Tratamiento de la deficiencia de hierro con carboximaltosa ferrica.
EA202191858A1 (ru) * 2019-06-12 2021-11-12 Фармакосмос Холдинг А/С Лечение дефицита железа у субъектов с риском нежелательных явлений со стороны сердечно-сосудистой системы и железо для лечения фибрилляции предсердий
EP4347022A1 (en) * 2021-05-27 2024-04-10 Keryx Biopharmaceuticals, Inc. Pediatric formulations of ferric citrate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE351366B (cg-RX-API-DMAC10.html) * 1965-06-08 1972-11-27 Teikoku Hormone Mfg Co Ltd
US20050203169A1 (en) * 2001-08-06 2005-09-15 Moskowitz David W. Methods and compositions for treating diseases associated with excesses in ACE
TWI335218B (en) 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
NZ566743A (en) * 2005-08-18 2010-07-30 Globoasia Llc Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same
KR20080094013A (ko) * 2006-01-30 2008-10-22 글로보아시아 엘엘씨 연조직의 석회화 역전, 예방, 지연 또는 안정화 방법
EP1978808B1 (en) 2006-01-30 2018-08-29 Panion & BF Biotech Inc. Ferric citrate for reversing, preventing, delaying or stabilizing soft tissue calcification
KR20120046753A (ko) * 2009-07-21 2012-05-10 케릭스 바이오파마슈티컬스 인코포레이티드 구연산철 투여형태
JP5827326B2 (ja) * 2010-07-07 2015-12-02 アーデリクス，インコーポレーテッド リン酸輸送を阻害する化合物及び方法
SG11201408521WA (en) * 2012-06-21 2015-01-29 Keryx Biopharmaceuticals Inc Use of ferric citrate in the treatment of chronic kidney disease patients

Also Published As

Publication number Publication date
WO2015066593A1 (en) 2015-05-07
JP2019206562A (ja) 2019-12-05
MX2016005734A (es) 2016-11-08
US20250360167A1 (en) 2025-11-27
EP3747432A1 (en) 2020-12-09
JP2021073230A (ja) 2021-05-13
SG11201603091QA (en) 2016-05-30
TW201609088A (zh) 2016-03-16
EP3065734A4 (en) 2017-05-17
KR20160096597A (ko) 2016-08-16
US20160256486A1 (en) 2016-09-08
EA201690926A1 (ru) 2016-09-30
CA2928200A1 (en) 2015-05-07
BR112016009901A8 (pt) 2020-04-14
AU2014341975A1 (en) 2016-05-19
TW202203910A (zh) 2022-02-01
US20190307791A1 (en) 2019-10-10
HK1223031A1 (zh) 2017-07-21
JP2016535780A (ja) 2016-11-17
CN105873583A (zh) 2016-08-17
IL245317A0 (en) 2016-06-30
JP6828100B2 (ja) 2021-02-10
TWI744215B (zh) 2021-11-01
EP3065734A1 (en) 2016-09-14

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