KR102381695B1 - 자기 혼합 장치 및 방법 - Google Patents

자기 혼합 장치 및 방법 Download PDF

Info

Publication number
KR102381695B1
KR102381695B1 KR1020177001571A KR20177001571A KR102381695B1 KR 102381695 B1 KR102381695 B1 KR 102381695B1 KR 1020177001571 A KR1020177001571 A KR 1020177001571A KR 20177001571 A KR20177001571 A KR 20177001571A KR 102381695 B1 KR102381695 B1 KR 102381695B1
Authority
KR
South Korea
Prior art keywords
delete delete
shaft
chamber
magnetically responsive
magnet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020177001571A
Other languages
English (en)
Korean (ko)
Other versions
KR20170018957A (ko
Inventor
더그 휘트먼
제임스 하이슬러
콜린 보자르
저메인 씨유
찰스 콜린스
에릭 스미스
Original Assignee
루미넥스 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 루미넥스 코포레이션 filed Critical 루미넥스 코포레이션
Priority to KR1020227010091A priority Critical patent/KR102513883B1/ko
Publication of KR20170018957A publication Critical patent/KR20170018957A/ko
Application granted granted Critical
Publication of KR102381695B1 publication Critical patent/KR102381695B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/25—Mixers with loose mixing elements, e.g. loose balls in a receptacle
    • B01F33/251—Mixers with loose mixing elements, e.g. loose balls in a receptacle using balls as loose mixing element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/813—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles mixing simultaneously in two or more mixing receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90—Heating or cooling systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F7/00—Magnets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90—Heating or cooling systems
    • B01F2035/99—Heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Power Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
KR1020177001571A 2014-06-18 2015-06-05 자기 혼합 장치 및 방법 Active KR102381695B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227010091A KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462013648P 2014-06-18 2014-06-18
US62/013,648 2014-06-18
PCT/US2015/034332 WO2015195357A1 (en) 2014-06-18 2015-06-05 Apparatus and methods for magnetic mixing

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020227010091A Division KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Publications (2)

Publication Number Publication Date
KR20170018957A KR20170018957A (ko) 2017-02-20
KR102381695B1 true KR102381695B1 (ko) 2022-04-01

Family

ID=54869086

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020177001571A Active KR102381695B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법
KR1020227010091A Active KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020227010091A Active KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Country Status (8)

Country Link
US (2) US10179899B2 (enExample)
EP (2) EP3157658B1 (enExample)
JP (2) JP6491240B2 (enExample)
KR (2) KR102381695B1 (enExample)
CN (2) CN110575781B (enExample)
AU (1) AU2015277637B2 (enExample)
CA (1) CA2951649C (enExample)
WO (1) WO2015195357A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110575781B (zh) 2014-06-18 2022-07-29 卢米耐克斯公司 用于磁混合的设备和方法
FR3038526A1 (fr) * 2015-07-06 2017-01-13 Provaine Systeme de fabrication d'une formulation
US10953376B2 (en) * 2015-09-03 2021-03-23 Tetracore, Inc. Device and method for mixing and bubble removal
CN113015910A (zh) * 2019-04-22 2021-06-22 深圳迈瑞生物医疗电子股份有限公司 一种磁珠试剂的混匀装置、混匀方法以及样本分析设备
KR102092003B1 (ko) * 2019-12-05 2020-05-15 한창기전 주식회사 산화 및 전처리 장치 일체형 유체이동 시스템을 탑재한 총인 및 총질소 측정시스템

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911555A (en) 1989-05-04 1990-03-27 The Jackson Laboratory Magnetic stirrer for multiple samples
US20020154570A1 (en) 2001-04-24 2002-10-24 Dade Behring Inc. Method and apparatus for mixing liquid samples in a container using rotating magnetic fields
JP2004521739A (ja) 2000-11-01 2004-07-22 デイド・ベーリング・インコーポレイテッド 渦作用を使用して液体サンプルを混合する方法および装置

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2774803A (en) 1952-09-20 1956-12-18 Asea Ab Inductive stirring device for metallurgical furnace
FR2109370A5 (enExample) * 1970-10-14 1972-05-26 Bernard Du Grail Alain
US4040605A (en) * 1976-07-14 1977-08-09 Marvin Stanley Towsend Magnetic stirring apparatus
US5306510A (en) 1988-01-14 1994-04-26 Cyberlab, Inc. Automated pipetting system
US5352036A (en) 1992-09-23 1994-10-04 Habley Medical Technology Corporation Method for mixing and dispensing a liquid pharmaceutical with a miscible component
US5599660A (en) 1993-01-19 1997-02-04 Pharmacia Biotech Inc. Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
JPH09500826A (ja) 1993-07-30 1997-01-28 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 向流多相液体分離のための装置
DE19644302A1 (de) 1995-11-28 1997-06-05 Boehringer Mannheim Gmbh Verfahren zum Nachweis von Telomerase-Aktivität
DE69839294T2 (de) 1997-09-29 2009-04-09 F. Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen
US6086831A (en) * 1998-06-10 2000-07-11 Mettler-Toledo Bohdan, Inc. Modular reaction block assembly with thermoelectric cooling and heating
US6176609B1 (en) * 1998-10-13 2001-01-23 V & P Scientific, Inc. Magnetic tumble stirring method, devices and machines for mixing in vessels
US6793167B2 (en) * 1999-01-12 2004-09-21 Island Oasis Cocktail Company, Inc. Food processing apparatus including magnetic drive
US6357907B1 (en) 1999-06-15 2002-03-19 V & P Scientific, Inc. Magnetic levitation stirring devices and machines for mixing in vessels
AU5776400A (en) 1999-06-30 2001-01-31 Quidel Corporation Method and kit for measuring total pyridinium crosslinks
CN1399716A (zh) 1999-08-05 2003-02-26 布赖恩·威廉·金 直接吸入一反应和注射装置及使用方法
JP2002152308A (ja) * 2000-11-09 2002-05-24 Nec Corp データ通信システム、その通信方法及びその通信プログラムを記録した記録媒体
EP1243315A1 (en) * 2001-03-22 2002-09-25 Avantium International B.V. Stirring device and method for measuring a parameter of the substance to be stirred
US20030017620A1 (en) * 2001-06-21 2003-01-23 Carron Keith T. Lyophilization of colloidal metals for surface enhanced Raman scattering
US6461034B1 (en) 2001-11-14 2002-10-08 V & P Scientific, Inc. Use of a bubble paddle tumble stirrer to mix the contents of a vessel while the contents are being removed
EP1546383A4 (en) 2002-09-17 2006-08-30 Pharmacia Corp ISOLATION OF GENETIC MOLECULES FROM A COMPLEX BIODEGRAPHIC FOR USE IN GENETIC EXPRESSION ANALYSIS
US7351337B1 (en) 2003-11-07 2008-04-01 Chester Milo Magnetic fuel conditioning apparatus
US7484880B2 (en) 2005-06-24 2009-02-03 V & P Scientific, Inc. Vortex stirring of vessels in a two-dimensional array
JP4981295B2 (ja) * 2005-10-04 2012-07-18 キヤノン株式会社 Ｄｎａ処理方法およびｄｎａ処理装置
EP2038051B1 (en) * 2006-06-21 2015-06-10 Spinomix S.A. A device for manipulating and mixing magnetic particles in a liquid medium and its use
WO2008008965A2 (en) * 2006-07-14 2008-01-17 Sigma-Aldrich Co. Magnetic stirrer
EP2384432B1 (en) * 2007-06-21 2016-12-28 Gen-Probe Incorporated Instrument and receptacles for performing processes
US7791441B1 (en) * 2008-04-15 2010-09-07 Jefferson George F Magnetically powered spinning magnet
EP2349549B1 (en) 2008-09-16 2012-07-18 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, and system
EP2394175B1 (en) 2009-02-09 2016-02-03 caprotec bioanalytics GmbH Devices, systems and methods for separating magnetic particles
FR2972646B1 (fr) * 2011-03-14 2015-02-27 Total Sa Melange d'un fluide multiphase
US9340417B2 (en) * 2011-06-29 2016-05-17 The Regents Of The University Of California Magnetic recovery method of magnetically responsive high-aspect ratio photoresist microstructures
US8657484B1 (en) * 2012-01-18 2014-02-25 The United States Of America As Represented By The Secretary Of The Army Apparatus for mixing contents enclosed within a container
DE102012201475B4 (de) * 2012-02-01 2014-12-18 Gna Biosolutions Gmbh Verfahren zum Vervielfältigen von Nukleinsäuren
WO2013192351A1 (en) * 2012-06-20 2013-12-27 Bio-Rad Laboratories, Inc. Stabilized droplets for calibration and testing
CN110575781B (zh) 2014-06-18 2022-07-29 卢米耐克斯公司 用于磁混合的设备和方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911555A (en) 1989-05-04 1990-03-27 The Jackson Laboratory Magnetic stirrer for multiple samples
JP2004521739A (ja) 2000-11-01 2004-07-22 デイド・ベーリング・インコーポレイテッド 渦作用を使用して液体サンプルを混合する方法および装置
US20020154570A1 (en) 2001-04-24 2002-10-24 Dade Behring Inc. Method and apparatus for mixing liquid samples in a container using rotating magnetic fields

Also Published As

Publication number Publication date
KR20220044381A (ko) 2022-04-07
US20190093061A1 (en) 2019-03-28
EP3157658A4 (en) 2018-02-21
WO2015195357A1 (en) 2015-12-23
CN110575781B (zh) 2022-07-29
JP2019110913A (ja) 2019-07-11
CN110575781A (zh) 2019-12-17
EP3892366A1 (en) 2021-10-13
CN106488799A (zh) 2017-03-08
JP2017524352A (ja) 2017-08-31
CA2951649C (en) 2023-10-03
EP3157658B1 (en) 2021-10-13
KR102513883B1 (ko) 2023-03-24
US10851336B2 (en) 2020-12-01
CA2951649A1 (en) 2015-12-23
AU2015277637A1 (en) 2017-01-05
US10179899B2 (en) 2019-01-15
AU2015277637B2 (en) 2019-03-28
JP6754458B2 (ja) 2020-09-09
US20150368601A1 (en) 2015-12-24
EP3157658A1 (en) 2017-04-26
JP6491240B2 (ja) 2019-03-27
CN106488799B (zh) 2019-10-08
KR20170018957A (ko) 2017-02-20

Similar Documents

Publication Publication Date Title
JP6754458B2 (ja) 磁気混合のための装置及び方法
Long et al. Fundamentals of magnet-actuated droplet manipulation on an open hydrophobic surface
ES2438989T3 (es) Dispositivos, sistemas y métodos accionadores de gotitas
Ohashi et al. A simple device using magnetic transportation for droplet-based PCR
Zhang et al. Microfluidic DNA amplification—A review
US9566558B2 (en) Device for manipulation of packets in micro-containers, in particular in microchannels
CA2862946C (en) Stirring device and gear train
US12220675B2 (en) Device and method for mixing and bubble removal
Jiang et al. Magnetically responsive manipulation of droplets and bubbles
JP2018528409A (ja) 氷核形成剤を含む凍結融解バルブを備える流体装置と関連の操作及び分析方法
HK40061931A (en) Method for magnetic mixing
HK40017592A (en) Apparatus and methods for magnetic mixing
HK40017592B (en) Apparatus and methods for magnetic mixing
CN105296344A (zh) 核酸扩增反应装置
HK1234001A1 (en) Apparatus and methods for magnetic mixing
HK1234001B (zh) 用於磁混合的设备和方法
CN104877988A (zh) 核酸扩增方法
JP5910304B2 (ja) 熱サイクル装置
Shikida et al. Droplet introduction into a pen-shaped portable reaction system by gravity and interfacial forces
EP2923763A1 (en) Biochip
JP2017112937A (ja) 熱サイクル装置及びその制御方法
CN105273995A (zh) 核酸扩增反应装置以及其控制方法

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20170118

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20200311

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20210702

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20220117

PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20220325

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20220329

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20220330

End annual number: 3

Start annual number: 1

PG1601 Publication of registration