KR102381695B1 - 자기 혼합 장치 및 방법 - Google Patents

자기 혼합 장치 및 방법 Download PDF

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Publication number
KR102381695B1
KR102381695B1 KR1020177001571A KR20177001571A KR102381695B1 KR 102381695 B1 KR102381695 B1 KR 102381695B1 KR 1020177001571 A KR1020177001571 A KR 1020177001571A KR 20177001571 A KR20177001571 A KR 20177001571A KR 102381695 B1 KR102381695 B1 KR 102381695B1
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South Korea
Prior art keywords
delete delete
shaft
chamber
magnetically responsive
magnet
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Expired - Fee Related
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KR1020177001571A
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English (en)
Korean (ko)
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KR20170018957A (ko
Inventor
더그 휘트먼
제임스 하이슬러
콜린 보자르
저메인 씨유
찰스 콜린스
에릭 스미스
Original Assignee
루미넥스 코포레이션
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Priority to KR1020227010091A priority Critical patent/KR102513883B1/ko
Publication of KR20170018957A publication Critical patent/KR20170018957A/ko
Application granted granted Critical
Publication of KR102381695B1 publication Critical patent/KR102381695B1/ko
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/25Mixers with loose mixing elements, e.g. loose balls in a receptacle
    • B01F33/251Mixers with loose mixing elements, e.g. loose balls in a receptacle using balls as loose mixing element
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/81Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/813Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles mixing simultaneously in two or more mixing receptacles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F7/00Magnets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • B01F2035/99Heating
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Power Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
KR1020177001571A 2014-06-18 2015-06-05 자기 혼합 장치 및 방법 Expired - Fee Related KR102381695B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227010091A KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462013648P 2014-06-18 2014-06-18
US62/013,648 2014-06-18
PCT/US2015/034332 WO2015195357A1 (en) 2014-06-18 2015-06-05 Apparatus and methods for magnetic mixing

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020227010091A Division KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Publications (2)

Publication Number Publication Date
KR20170018957A KR20170018957A (ko) 2017-02-20
KR102381695B1 true KR102381695B1 (ko) 2022-04-01

Family

ID=54869086

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020177001571A Expired - Fee Related KR102381695B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법
KR1020227010091A Active KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020227010091A Active KR102513883B1 (ko) 2014-06-18 2015-06-05 자기 혼합 장치 및 방법

Country Status (8)

Country Link
US (2) US10179899B2 (enExample)
EP (2) EP3892366A1 (enExample)
JP (2) JP6491240B2 (enExample)
KR (2) KR102381695B1 (enExample)
CN (2) CN110575781B (enExample)
AU (1) AU2015277637B2 (enExample)
CA (1) CA2951649C (enExample)
WO (1) WO2015195357A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102381695B1 (ko) 2014-06-18 2022-04-01 루미넥스 코포레이션 자기 혼합 장치 및 방법
FR3038526A1 (fr) * 2015-07-06 2017-01-13 Provaine Systeme de fabrication d'une formulation
US10953376B2 (en) * 2015-09-03 2021-03-23 Tetracore, Inc. Device and method for mixing and bubble removal
CN113015910A (zh) * 2019-04-22 2021-06-22 深圳迈瑞生物医疗电子股份有限公司 一种磁珠试剂的混匀装置、混匀方法以及样本分析设备
KR102092003B1 (ko) * 2019-12-05 2020-05-15 한창기전 주식회사 산화 및 전처리 장치 일체형 유체이동 시스템을 탑재한 총인 및 총질소 측정시스템

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911555A (en) 1989-05-04 1990-03-27 The Jackson Laboratory Magnetic stirrer for multiple samples
US20020154570A1 (en) 2001-04-24 2002-10-24 Dade Behring Inc. Method and apparatus for mixing liquid samples in a container using rotating magnetic fields
JP2004521739A (ja) 2000-11-01 2004-07-22 デイド・ベーリング・インコーポレイテッド 渦作用を使用して液体サンプルを混合する方法および装置

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2774803A (en) 1952-09-20 1956-12-18 Asea Ab Inductive stirring device for metallurgical furnace
FR2109370A5 (enExample) * 1970-10-14 1972-05-26 Bernard Du Grail Alain
US4040605A (en) * 1976-07-14 1977-08-09 Marvin Stanley Towsend Magnetic stirring apparatus
US5306510A (en) 1988-01-14 1994-04-26 Cyberlab, Inc. Automated pipetting system
US5352036A (en) 1992-09-23 1994-10-04 Habley Medical Technology Corporation Method for mixing and dispensing a liquid pharmaceutical with a miscible component
US5599660A (en) 1993-01-19 1997-02-04 Pharmacia Biotech Inc. Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
DK0711193T3 (da) 1993-07-30 1998-05-11 Du Pont Apparat til modstrøms flerfase væske adskillelse
DE19644302A1 (de) 1995-11-28 1997-06-05 Boehringer Mannheim Gmbh Verfahren zum Nachweis von Telomerase-Aktivität
DE69839294T2 (de) * 1997-09-29 2009-04-09 F. Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen
US6086831A (en) * 1998-06-10 2000-07-11 Mettler-Toledo Bohdan, Inc. Modular reaction block assembly with thermoelectric cooling and heating
US6176609B1 (en) * 1998-10-13 2001-01-23 V & P Scientific, Inc. Magnetic tumble stirring method, devices and machines for mixing in vessels
US6793167B2 (en) * 1999-01-12 2004-09-21 Island Oasis Cocktail Company, Inc. Food processing apparatus including magnetic drive
US6357907B1 (en) 1999-06-15 2002-03-19 V & P Scientific, Inc. Magnetic levitation stirring devices and machines for mixing in vessels
AU5776400A (en) 1999-06-30 2001-01-31 Quidel Corporation Method and kit for measuring total pyridinium crosslinks
WO2001011336A1 (en) 1999-08-05 2001-02-15 Harrison, Bruce Trading As Sxy Tech Direct aspiration-reaction and injection device and methods of use
JP2002152308A (ja) * 2000-11-09 2002-05-24 Nec Corp データ通信システム、その通信方法及びその通信プログラムを記録した記録媒体
EP1243315A1 (en) * 2001-03-22 2002-09-25 Avantium International B.V. Stirring device and method for measuring a parameter of the substance to be stirred
US20030017620A1 (en) * 2001-06-21 2003-01-23 Carron Keith T. Lyophilization of colloidal metals for surface enhanced Raman scattering
US6461034B1 (en) 2001-11-14 2002-10-08 V & P Scientific, Inc. Use of a bubble paddle tumble stirrer to mix the contents of a vessel while the contents are being removed
WO2004027024A2 (en) * 2002-09-17 2004-04-01 Pharmacia Corporation Isolation of genetic molecules from a complex biological construct for use in genetic expression analysis
US7351337B1 (en) 2003-11-07 2008-04-01 Chester Milo Magnetic fuel conditioning apparatus
US7484880B2 (en) 2005-06-24 2009-02-03 V & P Scientific, Inc. Vortex stirring of vessels in a two-dimensional array
JP4981295B2 (ja) * 2005-10-04 2012-07-18 キヤノン株式会社 Dna処理方法およびdna処理装置
EP2992951A1 (en) * 2006-06-21 2016-03-09 Spinomix S.A. A method for manipulating and mixing magnetic particles in a liquid medium
WO2008008965A2 (en) * 2006-07-14 2008-01-17 Sigma-Aldrich Co. Magnetic stirrer
CA2691197C (en) 2007-06-21 2013-03-12 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
US7791441B1 (en) * 2008-04-15 2010-09-07 Jefferson George F Magnetically powered spinning magnet
WO2010033599A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
WO2010089138A1 (en) * 2009-02-09 2010-08-12 Caprotec Bioanalytics Gmbh Devices, systems and methods for separating magnetic particles
FR2972646B1 (fr) * 2011-03-14 2015-02-27 Total Sa Melange d'un fluide multiphase
US9340417B2 (en) * 2011-06-29 2016-05-17 The Regents Of The University Of California Magnetic recovery method of magnetically responsive high-aspect ratio photoresist microstructures
US8657484B1 (en) * 2012-01-18 2014-02-25 The United States Of America As Represented By The Secretary Of The Army Apparatus for mixing contents enclosed within a container
DE102012201475B4 (de) * 2012-02-01 2014-12-18 Gna Biosolutions Gmbh Verfahren zum Vervielfältigen von Nukleinsäuren
EP2864495A4 (en) * 2012-06-20 2016-06-08 Bio Rad Laboratories STABILIZED DROPLETS FOR CALIBRATING AND TESTING
KR102381695B1 (ko) 2014-06-18 2022-04-01 루미넥스 코포레이션 자기 혼합 장치 및 방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911555A (en) 1989-05-04 1990-03-27 The Jackson Laboratory Magnetic stirrer for multiple samples
JP2004521739A (ja) 2000-11-01 2004-07-22 デイド・ベーリング・インコーポレイテッド 渦作用を使用して液体サンプルを混合する方法および装置
US20020154570A1 (en) 2001-04-24 2002-10-24 Dade Behring Inc. Method and apparatus for mixing liquid samples in a container using rotating magnetic fields

Also Published As

Publication number Publication date
JP2019110913A (ja) 2019-07-11
WO2015195357A1 (en) 2015-12-23
EP3892366A1 (en) 2021-10-13
CN110575781A (zh) 2019-12-17
JP2017524352A (ja) 2017-08-31
CN106488799B (zh) 2019-10-08
AU2015277637A1 (en) 2017-01-05
US10851336B2 (en) 2020-12-01
US20150368601A1 (en) 2015-12-24
JP6754458B2 (ja) 2020-09-09
US10179899B2 (en) 2019-01-15
CN106488799A (zh) 2017-03-08
CN110575781B (zh) 2022-07-29
JP6491240B2 (ja) 2019-03-27
AU2015277637B2 (en) 2019-03-28
KR20170018957A (ko) 2017-02-20
CA2951649A1 (en) 2015-12-23
US20190093061A1 (en) 2019-03-28
EP3157658A1 (en) 2017-04-26
CA2951649C (en) 2023-10-03
EP3157658A4 (en) 2018-02-21
KR102513883B1 (ko) 2023-03-24
KR20220044381A (ko) 2022-04-07
EP3157658B1 (en) 2021-10-13

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