KR102346313B1 - Modular micro-fluidic chip - Google Patents

Abstract

Disclosed is a modular fluid chip capable of quantifying liquids of various capacities using a single fluid chip, thereby reducing costs.
The modular fluid chip includes a core including a plurality of chambers, and a cover coupled to the core and comprising at least one flow path configured to be connected to at least one of the plurality of chambers or to connect at least two or more of the plurality of chambers. include

Description

Modular Fluid Chip {MODULAR MICRO-FLUIDIC CHIP}

The present invention relates to a modular fluid chip, and more particularly, to a modular fluid chip capable of quantifying a fluid and connectable to other modular fluid chips.

Lab-on-a-chip (LOC) technology is in the spotlight to overcome the shortcomings of existing diagnostic techniques. Lab-on-a-chip technology is a representative example of convergence technology of NT, IT, and BT. Using technologies such as MEMS or NEMS, all pre-processing and analysis steps of the sample, such as dilution, mixing, reaction, separation, and quantification, are performed on a single chip. skills that make it happen.

Such microfluidic devices to which the lab-on-a-chip technology is applied analyze and diagnose the flow of a fluid sample flowing through a reaction channel or a reaction between a fluid sample and a reagent supplied to the reaction channel, as well as control and control the fluid sample. It is manufactured in a form in which a plurality of units necessary for analysis are provided on a small chip of several cm2 in size made of glass, silicon, or plastic so that various related steps of processing and manipulation can be performed on a single chip.

Specifically, the microfluidic device includes a chamber capable of confinement of a small amount of fluid, a reaction channel through which the fluid can flow, a valve capable of regulating the flow of the fluid, and various functional units capable of receiving the fluid and performing predetermined functions. and so on.

However, since the conventional microfluidic device is manufactured to have functions related to a plurality of microfluidic devices according to the purpose of the experiment, even if there is a problem or change in one function, the entire device must be newly manufactured, and thus the manufacturing cost As well as this increase, there was a problem that management was not easy.

In addition, as the conventional microfluidic device is manufactured so that the liquid can be quantified with only one predetermined quantitative value, there is a problem in that it is impossible to quantify the liquid of various capacities through one microfluidic device.

In addition, as a plurality of microfluidic devices to which different quantitative values are applied must be separately provided in order to quantify liquids of various capacities, there is a problem in that the cost increases.

Registered Patent Publication No. 10-1780429

The present invention has been devised to solve the above problems, and an object of the present invention is to provide a modular fluid chip capable of quantifying liquids of various capacities using a single fluid chip, thereby reducing costs. will do

Another object of the present invention is to provide a modular fluid chip capable of independently performing preset functions and selectively connected to other modular fluid chips to implement one fluid system.

The problems of the present invention are not limited to the problems mentioned above, and other problems not mentioned will be clearly understood by those skilled in the art from the following description.

A modular fluid chip according to an embodiment of the present invention for solving the above problems includes a core including a plurality of chambers; and a cover coupled to the core and connected to at least one of the plurality of chambers or including at least one flow path configured to connect at least two or more of the plurality of chambers.

The core may include: a first channel provided at a location spaced apart from the plurality of chambers and connectable to the at least one flow path; and a second channel connected to at least one of the plurality of chambers and connectable to the at least one flow path.

The storage capacity of each chamber may represent a value reflecting the storage capacity of a channel connected to each chamber.

The first channel and the second channel may have a smaller volume than that of the plurality of chambers.

The core may be manufactured integrally through 3D printing or may be manufactured in the form of a plurality of modules that can be combined and separated through injection molding.

The at least one flow path may connect the plurality of chambers to each other so that the fluid may be filled in an order of increasing storage capacity.

The cover may be provided in the form of a detachable film on the outer surface of the core.

The cover may include: a first cover member detachable from the outer surface of the core and having the at least one flow path provided therein; and a second cover member attached to the outer surface of the first cover member and configured to prevent the fluid filled in the at least one flow path from flowing out to an external space.

The cover may include: a fluid inlet connected to a first chamber to be filled with a fluid first among a plurality of chambers connected to the at least one flow path, and into which a fluid is injected; and an air outlet connected to a second chamber to be filled with a fluid last among a plurality of chambers connected to the at least one flow path, and through which air in the plurality of chambers is discharged when the plurality of chambers are filled with a fluid; can do.

It may further include an air filter installed at the air outlet and capable of removing air bubbles from the fluid.

The air filter may be made of a hydrophobic material capable of removing air bubbles from a hydrophilic fluid.

The air filter may be made of one or more hydrophobic materials selected from the group consisting of polytetrafluore ethylene (PTFE), polyethylene terephtalate (PET), and polyvinyl chloride.

The air filter may be made of a hydrophilic material capable of removing air bubbles from the hydrophobic fluid.

The air filter may be provided with a hydrophobic material on one surface and a hydrophilic material on the other surface to remove air bubbles from the mixed fluid in which the hydrophilic fluid and the hydrophobic fluid are mixed.

a fluid sensor for detecting a fluid and generating it as an electrical signal; and an opening/closing valve configured to open and close the fluid inlet according to the presence or absence of the electrical signal.

The cover may include: a first connection channel connecting the fluid inlet and the first chamber to each other and guiding the fluid injected through the fluid inlet to the first chamber; a second connection channel branched from the first connection channel to connect the external space and the first chamber to each other, and to guide the fluid flowing inward through the first chamber to the external space; a third connection channel connecting the air outlet and the second chamber to each other and guiding the fluid filled in the second chamber to the air outlet; and a fourth connection channel branched from the third connection channel to connect the external space and the second chamber to each other, and guide air injected from the outside to the second chamber.

A modular fluid chip according to another embodiment of the present invention includes a core having at least one chamber; and a base coupled to the core and having at least one flow path configured to be connected to the at least one chamber.

A modular fluid chip according to another embodiment of the present invention includes a core including a core cell having at least one chamber and a dummy cell provided in a solid form; and a cover coupled to the core cell and including at least one flow path configured to be connected to the at least one chamber.

According to an embodiment of the present invention, by connecting at least one or two or more of a plurality of chambers provided in the core according to a set quantitative value using a removable cover on the outer surface of the core, various storage spaces can be created, and through this Liquid quantification of various volumes may be possible through a single fluid chip.

In addition, as liquid quantification of various capacities is possible through a single fluid chip, cost can be reduced.

In addition, by forming the fluid chip in the form of a module, it is possible to independently perform a preset function or to be connected to another modular fluid chip to implement a single fluid system to which various functions are complexly applied.

In addition, when applied to a fluid system, even when a specific part is deformed or damaged, only the modular fluid chip of the corresponding part can be replaced, so that management is easy and cost can be reduced.

1 is a perspective view showing a modular fluid chip according to a first embodiment of the present invention.
2 is an exploded perspective view showing a modular fluid chip according to a first embodiment of the present invention.
3 is a diagram schematically illustrating a process in which a fluid is filled in a modular fluid chip according to a first embodiment of the present invention.
4A and 4B are perspective views illustrating a modular fluid chip according to a second embodiment of the present invention.
5 is a perspective view illustrating a modular fluid chip according to a third embodiment of the present invention.
6 is a diagram schematically illustrating an end structure of a chamber connected to a flow path.
7 is a plan view illustrating a modular fluid chip according to a fourth embodiment of the present invention.
8 is a cross-sectional view taken along line VIII - VIII of FIG.
9 is a plan view illustrating a modular fluid chip according to a fifth embodiment of the present invention.
FIG. 10 is a cross-sectional view taken along line X - X of FIG. 9 .
11 is a perspective view illustrating a modular fluid chip according to a sixth embodiment of the present invention.
12 is an exploded perspective view of FIG. 11 ;

Hereinafter, various embodiments will be described in more detail with reference to the accompanying drawings. The embodiments described herein may be variously modified. Certain embodiments may be depicted in the drawings and described in detail in the detailed description. However, the specific embodiments disclosed in the accompanying drawings are only provided to facilitate understanding of the various embodiments. Accordingly, the technical spirit is not limited by the specific embodiments disclosed in the accompanying drawings, and it should be understood to include all equivalents or substitutes included in the spirit and scope of the invention.

Terms including an ordinal number such as 1st, 2nd, etc. may be used to describe various components, but these components are not limited by the above-mentioned terms. The above terminology is used only for the purpose of distinguishing one component from another component.

In this specification, terms such as "comprises" or "have" are intended to designate that the features, numbers, steps, operations, components, parts, or combinations thereof described in the specification exist, but one or more other features It should be understood that this does not preclude the existence or addition of numbers, steps, operations, components, parts, or combinations thereof. When an element is referred to as being “connected” or “connected” to another element, it is understood that it may be directly connected or connected to the other element, but other elements may exist in between. it should be On the other hand, when it is said that a certain element is "directly connected" or "directly connected" to another element, it should be understood that the other element does not exist in the middle.

Meanwhile, as used herein, a “module” or “unit” for a component performs at least one function or operation. In addition, a “module” or “unit” may perform a function or operation by hardware, software, or a combination of hardware and software. In addition, a plurality of “modules” or a plurality of “units” other than a “module” or “unit” to be performed in specific hardware or to be executed in at least one processor may be integrated into at least one module. The singular expression includes the plural expression unless the context clearly dictates otherwise.

In addition, in describing the present invention, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the gist of the present invention, the detailed description thereof will be abbreviated or omitted.

1 is a perspective view showing a modular fluid chip according to a first embodiment of the present invention, FIG. 2 is an exploded perspective view showing a modular fluid chip according to a first embodiment of the present invention, and FIG. 3 is a first embodiment of the present invention. A diagram schematically illustrating a process in which a fluid is filled in a modular fluid chip according to an embodiment.

1 and 2 , the modular fluid chip 100 (hereinafter referred to as 'modular fluid chip 100') according to the first embodiment of the present invention can quantify fluid, and other modular types It is provided in the form of a module selectively connectable to a fluid chip (not shown).

The modular fluid chip 100 is connected to a modular fluid chip (not shown) that performs other functions to implement a fluid flow system (not shown) of various structures. For example, the modular fluid chip 100 may be connected to other modular fluid chips in horizontal and vertical directions to implement one fluid flow system.

The fluid flow system implemented through the modular fluid chip 100 and other modular fluid chips may include sample collection, sample disruption, gene or Extraction of substances such as protein, filtering, mixing, storage, valve, amplification using polymerase chain reaction including RT-PCR, antigen-antibody reaction, affinity chromatography and electrical sensing, electrochemical sensing, capacitor An analysis/detection process such as type electrical sensing and optical sensing with or without a fluorescent material may be performed. However, the fluid flow system implemented through the modular fluid chip 100 is not necessarily limited to the above-described functions, and may perform various functions for fluid analysis and diagnosis. For example, the fluid flow system may be configured to enable a series of treatments such that a fluid enters, cells in the fluid are disrupted, filtered, a gene is amplified, and a fluorescent material is attached to the amplified gene to be observed.

In addition, the fluid flow system may implement a factory-on-a-chip technology through connection with another fluid flow system (not shown). Through this, analysis and diagnosis of different fluids can be simultaneously performed through a plurality of fluid flow systems, and all fluid-related experiments (eg, chemical reaction and material synthesis) can be simultaneously performed.

The modular fluid chip 100 includes a core 110 and a cover 120 .

The core 110 may be manufactured integrally through 3D printing or may be provided in the form of a plurality of modules that can be combined and separated through injection molding. However, the core 110 is not necessarily limited thereto, and may be manufactured using various techniques such as MEMS, CNC machining, imprinting, polymer casting, and the like.

The core 110 may be formed so that the entirety has transparency or a part has transparency so that the flow of the fluid flowing from the outside to the inside can be visually confirmed. Illustratively, the core 110 may be formed of at least one of an amorphous material such as glass, wood, a polymer resin, a metal, and an elastomer, or a combination thereof. However, the core 110 is not necessarily limited thereto, and may be formed of various materials.

The core 110 includes a plurality of chambers 111 each having a preset storage capacity.

The plurality of chambers 111 may be formed in the form of holes having a length in the vertical direction greater than an inner diameter to guide the fluid filled therein in the vertical direction.

The plurality of chambers 111 include a first chamber 111a having the largest storage capacity, a second chamber 111b having the smallest storage capacity, and a storage capacity of the first chamber 111a and a storage capacity of the second chamber 111c. It may include a third chamber 111c having a storage capacity value between the storage capacities.

Exemplarily, the first chamber 111a may have a storage capacity of 10 μL (microliter), the second chamber 111b may have a storage capacity of 2 μL, and the third chamber 111c may have a storage capacity of 5 μL. have. However, the storage capacities of the first chamber 111a , the second chamber 111b , and the third chamber 111c are not necessarily limited thereto, and various values may be changed and applied.

The first chamber 111a, the second chamber 111b, and the third chamber 111c may be provided in plurality in the core 110, respectively.

In the present embodiment, all of the plurality of chambers 111 are composed of six, but the plurality of chambers 111 is not necessarily limited thereto, and may be composed of a smaller number or a larger number of chambers.

The first chamber 111a, the second chamber 111b, and the third chamber 111c may have the same inner diameter. In addition, the first chamber 111a has the longest vertical length compared to the second chamber 111b and the third chamber 111c, and the third chamber 111c is longer than the second chamber 111b. It may have a length in the vertical direction.

The core 110 may further include a plurality of channels 112 connected to the plurality of chambers 111 .

The plurality of channels 112 may be formed in the form of holes having a length in the vertical direction greater than the inner diameter to guide the fluid filled therein in the vertical direction.

The plurality of channels 112 includes a first channel 112a that is indirectly connected to any one of the plurality of chambers 111 and a second channel 112b that is directly connected to any one of the plurality of chambers 111 . may include

The first channel 112a is provided in a position spaced apart from the plurality of chambers 111 in the core 110 , and is connected to at least one flow path 120a provided in a cover 120 to be described later, thereby providing a plurality of chambers 111 . ) can be connected to any one of the

For example, the first channel 112a may have the same length as the first chamber 111a and may be indirectly connected to the first chamber 111a through the flow path 120a provided in the cover 120 .

The second channel 112b may be directly connected to at least one of the plurality of chambers 111 .

For example, the second channel 112b may have a shorter length than the first channel 112a and may be directly connected to the second chamber 111b or directly connected to the third chamber 111c. The second channel 112b connected to the second chamber 111b may have a length equal to the difference between the length of the first chamber 111a and the length of the second chamber 111b. In addition, the second channel 112b connected to the third chamber 111c may have a length equal to the difference between the length of the first chamber 111a and the length of the third chamber 111c.

The storage capacity of each chamber (the first chamber 111a, the second chamber 111b, and the third chamber 111c) is the storage capacity of each chamber (the first chamber 111a, the second chamber 111b, the third chamber 111c). )) and the connected channels (the first channel 112a and the second channel 112b) may represent a value in which the storage capacity is reflected.

For example, in the case of FIG. 1 , the storage capacity of the first chamber 111a may represent a value reflecting the storage capacity of the first chamber 111a and the first channel 112a connected to the first chamber 111a. . And, the storage capacity of the second chamber 111b represents a value reflecting the storage capacity of the second chamber 111b and the first channel 112a and the second channel 112b connected to the second chamber 111b, The storage capacity of the three chamber 111c may represent a value in which the storage capacity of the third chamber 111c and the first channel 112a and the second channel 112b connected to the third chamber 111c is reflected.

Accordingly, when the fluid is injected into the modular fluid chip 100 , a quantitative error due to the fluid filled in the plurality of channels 112 may be eliminated.

In addition, the plurality of channels 112 and the at least one flow path 120a may have a smaller volume than that of the plurality of chambers 111 . Through this, it is possible to minimize the quantitative error.

The plurality of channels 112 and the at least one flow path 120a may have the same inner diameter.

Through this, it is possible to prevent a phenomenon in which the pressure of the fluid is increased between the core 110 and the cover 120 or the fluid flow is unstable when the fluid flows.

That is, when the plurality of channels 112 and the at least one flow path 120a have a shape and size corresponding to each other and form a movement path of the fluid, a predictable flow velocity when the fluid is moved from one module to another module to be able to have In some conventional microfluidic flow devices, a fluid is transferred through a tube. In the case of a microfluidic device using a tube, there may be a difference in the width of the channel at the part where the tube and the device are connected, or a space may be created in the channel to cause vortexing in the fluid. Such a vortex may not only cause a sudden change in the flow rate, but also change the shape of the droplet. Alternatively, it may give a physical impact to substances in the fluid or impede the movement of substances. Accordingly, the plurality of channels 112 and the at least one flow path 120a have a shape and size corresponding to each other and form a movement path of the fluid, in addition to simply ensuring the connection between modules, a stable flow rate of the fluid and material to enable stable movement of

For example, the plurality of channels 112 and the at least one flow path 120a may have a circular cross-section or a polygonal or elliptical shape. However, the shape of the inner diameter is not limited thereto, and may be changed and applied to various sizes and shapes.

Referring to FIG. 6 , the end p1 of the chamber 111 connected to the flow path 120a may have a structure in which the size of the inner diameter gradually decreases toward the flow path 120a. For example, the opening of the chamber 111 in contact with the passage 120a may have the same inner diameter as that of the passage 120a.

Through this, it is possible to prevent air from remaining in the core 110 when the fluid flows.

1 and 2 , the cover 120 is coupled to the core 110 and includes at least one flow path 120a.

The at least one flow path 120a is connected to the at least one chamber 111 according to a preset quantitative value, and guides the fluid flowing therein in the horizontal direction.

In more detail, the at least one flow path 120a provided in the cover 120 is connected to at least one of the plurality of chambers 111 or connected to the plurality of chambers 111 so that the storage capacity of the chamber coincides with a preset quantitative value. ) is configured to connect at least two or more of

For example, when the quantitative value is set to 10 μL, at least one flow path 120a provided in the cover 120 may be connected to the first chamber 111a having a storage capacity of 10 μL. More specifically, when the quantitative value is set to 10 μL, at least one flow path 120a has a first chamber 111a having a storage capacity of 10 μL and a first channel 112a provided at one side of the first chamber 111a. ) can be connected to each other.

As another example, when the quantitative value is set to 19 μL, at least one flow path 120a provided in the cover 120 has a first chamber 111a having a storage capacity of 10 μL, a storage capacity of 5 μL as shown in FIG. 1 . A third chamber 111c having a , and a plurality of second chambers 111b each having a storage capacity of 2 μL may be connected to each other. More specifically, when the quantitative value is set to 19 μL, the at least one flow path 120a includes a first channel 112a provided on one side of the first chamber 111a, a first chamber 111a, and a first chamber. The first channel 112a provided at one side of the 111a and the third chamber 111c, the first channel 112a and the third chamber 111c provided at one side of the third chamber 111c, and the third chamber A second channel 112b directly connected to the 111c, a first channel 112a provided on one side of the second chamber 111b, a first channel 112a provided on one side of the second chamber 111b, and A second chamber 111b, a second channel 112b directly connected to the second chamber 111b, and a first channel 112a provided on one side of another second chamber 111b, and another second chamber A first channel 112a provided on one side of the 111b and another second chamber 111b may be connected to each other.

That is, in the modular fluid chip 100 , the cover 120 attached to the core 110 can be replaced, and the flow path 120a provided in the cover 120 includes at least one of the plurality of chambers 111 and the As it is connected or configured to connect at least two or more of the plurality of chambers 111 , it is possible to quantify the fluid with various capacities.

The at least one flow path 120a connects at least two or more of the plurality of chambers 111 to each other so that the sum of the storage capacities of the chambers corresponds to a preset quantitative value, and the chambers are filled in the order of the storage capacities of the chambers. can be connected to each other.

For example, referring to FIG. 3 , the at least one flow path 120a is a first chamber 111a having the largest storage capacity in which the fluid injected into the modular fluid chip 100 has the largest storage capacity, and a second flow path 120a having the next largest storage capacity. The first chamber 111a, the second chamber 111b, and the third chamber 111c can be connected to each other so that the three chambers 111c and the second chamber 111b having the smallest storage capacity can be filled in this order. have. Through this, the chamber 111 in which the fluid is filled can be minimized.

1 and 2 , the cover 120 is coupled to the upper and lower surfaces of the core 110 , respectively, and may be provided in the form of a detachable film on the outer surface of the core 110 .

The cover 120 may include a first cover member 121 and a second cover member 122 .

The first cover member 121 may be detachable from the outer surface of the core 110 . In addition, at least one flow path 120a may be provided inside the first cover member 121 .

For example, an adhesive layer (not shown) may be provided on one surface and the other surface of the first cover member 121 . Through this, one surface of the first cover member 121 may be detachably attached to the outer surface of the core 110 , and the other surface of the first cover member 121 may be coupled to a second cover member 122 to be described later. In addition, the first cover member 121 may be formed of a transparent or opaque material.

The second cover member 122 is formed in a shape corresponding to the outer shape of the first cover member 121 and may be attached to the outer surface of the first cover member 121 provided with an adhesive layer (not shown). Through this, the second cover member 122 may be configured to prevent the fluid filled in the at least one flow path 120a from flowing out to the external space.

For example, the second cover member 122 may be formed of a transparent material.

In addition, the cover 120 may further include a fluid inlet 123 and an air outlet 124 .

1 and 2 , the fluid inlet 123 may be formed through the first cover member 121 and the second cover member 122 . In addition, the fluid inlet 123 may be connected to the first chamber 111a to be filled with the fluid first among the plurality of chambers 111 connected to the at least one flow path 120a. In addition, the fluid inlet 123 may be connected to another modular fluid chip (not shown) or a separate fluid injection device (not shown). Through this, the fluid discharged from another modular fluid chip (not shown) or a separate fluid injection device (not shown) may be injected into the fluid inlet 123 .

The air outlet 124 may be formed through the first cover member 121 and the second cover member 122 . And, the air outlet 124 is connected to the second chamber 111b to be filled with the last fluid among the plurality of chambers 111 connected to the at least one flow path 120a to enable the flow of the fluid flowing in the chamber. . In addition, when the plurality of chambers 111 are filled with a fluid, the air outlet 124 may discharge the air inside the chamber moving in one direction to the outside.

Hereinafter, the modular fluid chip 200 according to the second embodiment of the present invention will be described.

For reference, each configuration for describing the modular fluid chip 200 according to the second embodiment of the present invention is used while describing the modular fluid chip 100 according to the first embodiment of the present invention for convenience of description. The same reference numerals are used, and the same or overlapping descriptions will be omitted.

4A and 4B are perspective views illustrating a modular fluid chip according to a second embodiment of the present invention.

4A, the modular fluid chip 200 (hereinafter referred to as 'modular fluid chip 200') according to the second embodiment of the present invention is configured to remove air bubbles from the fluid filled therein.

The modular fluid chip 200 may further include an air filter 150 installed at the air outlet 124 and capable of removing air bubbles from the fluid.

The air filter 150 is formed in the form of a film attachable to the outer surface of the cover 120 , and may be attached to the outer surface of the cover 120 to cover the air outlet 124 .

The air filter 150 may be configured to pass only air bubbles from the fluid filled in the plurality of chambers 111 . Accordingly, the fluid injected into the core 110 moves in one direction, fills the plurality of chambers 111 sequentially, and then is blocked by the air filter 150 installed in the air outlet 124 to automatically restrict the flow. can be

In one embodiment, the air filter 150 may be provided in the form of a hydrophobic material capable of removing air bubbles from a hydrophilic fluid, or in the form of a fibrous tissue coated with a hydrophobic material on the surface. Illustratively, the air filter 150 is made of one or more hydrophobic materials selected from the group consisting of polytetrafluore ethylene (PTFE), polyethylene terephtalate (PET), and polyvinyl chloride. can be provided.

In another embodiment, the air filter 150 may be provided in the form of a hydrophilic material capable of removing air bubbles from the hydrophobic fluid, or in the form of a fibrous tissue coated with a hydrophilic material on the surface.

In another embodiment, the air filter 150 is a double filter in which a hydrophobic material is provided on one surface and a hydrophilic material is provided on the other surface so as to remove air bubbles from a mixed fluid in which a hydrophilic fluid and a hydrophobic fluid are mixed. can be provided with

In addition, the modular fluid chip 200 detects the fluid filled in the chamber 111 at a specific location, and when the fluid is detected, blocks the inflow of the fluid to limit the flow of the fluid injected into the core 110 . do.

Referring to FIG. 4B , the modular fluid chip 200 detects the fluid and generates the fluid as an electrical signal, the fluid sensor 160, and the fluid inlet 123 depending on whether or not a signal is generated from the fluid sensor 160. It may further include an opening/closing valve 170 configured to open and close the .

In FIG. 4B , a plurality of fluid detection sensors 160 are provided and illustrated as being installed in each chamber 111a, 111b, and 111c, but the fluid detection sensor 160 is not limited thereto, and provided in the core 110. At least one may be provided according to the number of chambers or a preset flow path of the fluid.

In addition, the fluid sensor 160 installed in the chamber 111 may be disposed at a position where the fluid is finally filled.

That is, the fluid sensor 160 may be disposed at a position where the fluid is last filled in the selected chamber so as to detect a state in which the fluid is quantitatively filled in the selected chamber.

Exemplarily, the first fluid detection sensor 160a for detecting the fluid filled in the first chamber 111a is disposed at the upper end of the first chamber 111a connected to the flow path 120a, and the second chamber 111b ), the second fluid detection sensor 160b for detecting the fluid filled in the second chamber 111b is disposed at the upper end of the second channel 112b connected to the flow path 120a, and the third chamber 111c) The third fluid detection sensor 160c for sensing the fluid filled in the ventilator may be provided in the third chamber 111c and disposed at the upper end of the second channel 112b connected to the flow path 120a.

Meanwhile, the plurality of fluid detection sensors 160a, 160b, and 160c may be electrically connected to a separate control device (not shown) and selectively controlled through the control device (not shown). Therefore, when the plurality of fluid detection sensors 160a, 160b, and 160c come into contact with a fluid, all of them generate an electrical signal and transmit it to the control device (not shown), or generate only a selected part of the electrical signal to the control device (not shown) can be sent to

In addition, each fluid detection sensor (160a, 160b, 160c) may be provided as a flexible film-type electrode to be attached to the inner surface of the core 110, but is not necessarily limited thereto and may be changed in various forms. can

The opening/closing valve 170 may be electrically connected to a control device (not shown), and may open/close the fluid inlet 123 according to a control signal transmitted from the control device (not shown).

Specifically, the on/off valve 170 opens the fluid inlet 123 to allow the inflow of fluid when a control signal is not transmitted from the control device (not shown), and the fluid detection sensor 160 to the control device (not shown). ), the fluid inlet 123 may be closed so that the inflow of the fluid is blocked when an electrical signal notifying the detection of the fluid is transmitted and a control signal is transmitted from the control device (not shown).

Illustratively, the on/off valve 170 is installed at the upper end of the first channel 112a connected to the fluid inlet 123, and is a microvalve so that it can be installed inside the first channel 112a having a diameter of 1 mm or less. can be applied

As described above, in this modular fluid chip 200, the fluid detection sensor 160 detects a state in which the fluid is filled in a quantitative amount in the chamber, and the on/off valve 170 detects the presence or absence of a signal from the fluid detection sensor 160. By opening and closing the fluid inlet 123 through which the fluid is injected, the flow of the fluid can be restricted by automatically blocking the inflow of the fluid when the fluid is filled by a set amount. Hereinafter, the third embodiment of the present invention It will be described with respect to the modular fluid chip 300 according to the.

For reference, for each configuration for describing the modular fluid chip 300 according to the third embodiment of the present invention, for convenience of description, the modular fluid chip 100 according to the first and second embodiments of the present invention. , 200), the same reference numerals are used, and the same or overlapping descriptions will be omitted.

5 is a perspective view illustrating a modular fluid chip according to a third embodiment of the present invention.

Referring to FIG. 5 , the modular fluid chip 300 (hereinafter referred to as 'modular fluid chip 300') according to the third embodiment of the present invention is filled in a plurality of chambers 111 to receive a quantified fluid. configured to recover.

The modular fluid chip 200 may further include a plurality of connection channels 125 provided on the cover 120 and capable of injecting and discharging fluid, and allowing injection and discharging of air.

The plurality of connection channels 125 may include a first connection channel 125a, a second connection channel 125b, a third connection channel 125c, and a fourth connection channel 125d.

The first connection channel 125a may connect the fluid inlet 123 and the first chamber 111a to each other, and guide the fluid injected through the fluid inlet 123 to the first chamber 111a.

The second connection channel 125b is branched from the first connection channel 125a to connect the external space and the first chamber 111a to each other, and due to the air injected through the fourth connection channel 125d, the first chamber ( 111a), the fluid introduced inside can be guided to the external space.

Exemplarily, the first connection channel 125a and the second connection channel 125b connected to the first chamber 111a are directly connected to the first chamber 111a or through the flow path 120a to the first chamber ( It may be indirectly connected to the first chamber 111a through the first channel 112a connected to the 111a.

The third connection channel 125c connects the air outlet 124 and the second chamber 111b to each other, and guides the fluid filled in the second chamber 111b toward the air outlet 124 where the air filter 150 is installed. can do.

The fourth connection channel 125d may branch from the third connection channel 125c to connect the external space and the second chamber 111b to each other, and guide air injected from the outside to the second chamber 111b.

Exemplarily, the third connection channel 125c and the fourth connection channel 125d connected to the second chamber 111b are directly connected to the second chamber 111b or a second connection channel provided in the second chamber 111b. It may be indirectly connected to the second chamber 111b through the channel 112b.

Accordingly, after the fluid injected through the fluid inlet 123 is introduced into the first chamber 111a through the first connection channel 125a, the first chamber 111a, the third chamber 111c, and the third chamber 111c are sequentially introduced. It can be quantified by filling the second chamber (111b). At this time, the second connection channel 125b and the fourth connection channel 125d are maintained in a closed state through a separate member attached to an end of each channel. Then, the air in the chamber 111 moving in one direction together with the fluid flows into the third connection channel 125c and then into the external space through the air filter 150 disposed at the end of the third connection channel 125c. The fluid discharged and introduced into the third connection channel 125c may be supported by the air filter 150 disposed at the end after filling the third connection channel 125c to limit the flow.

In addition, when air is injected into the fourth connection channel 125d, the quantified fluid stored in the plurality of chambers 111 flows in a direction opposite to the direction in which the fluid is injected. Through this, the fluid stored in each chamber (111a, 111b, 111c) is discharged to the external space through the second connection channel (125b) in the order opposite to the order in which it was filled, and thus the quantified fluid can be completely recovered from the outside. have. At this time, the first connection channel (125a) is maintained in a closed state through a separate member attached to the end. And, the third connection channel 125c is continuously closed until the injection of air is stopped through the fluid remaining in the third connection channel 125c by being pressurized by the air injected into the fourth connection channel 125d. will maintain the status quo.

Hereinafter, the modular fluid chip 400 according to the fourth embodiment of the present invention will be described.

For reference, for each configuration for describing the modular fluid chip 400 according to the fourth embodiment of the present invention, for convenience of description, the modular fluid chip 100 according to the first to third embodiments of the present invention. , 200, and 300) are used the same reference numerals, and the same or overlapping descriptions will be omitted.

7 is a plan view showing a modular fluid chip according to a fourth embodiment of the present invention, and FIG. 8 is a cross-sectional view taken along line VIII-VIII of FIG. 7 .

7 and 8 , the modular fluid chip 400 includes a core 110 , a cover 120 , a housing 130 , and a connector 140 .

The core 110 includes a plurality of chambers 111 each having a preset storage capacity.

The plurality of chambers 111 may be formed in the form of holes having a length in the vertical direction greater than an inner diameter to guide the fluid filled therein in the vertical direction.

The plurality of chambers 111 include a first chamber 111a having the largest storage capacity, a second chamber 111b having the smallest storage capacity, and a storage capacity of the first chamber 111a and a storage capacity of the second chamber 111c. It may include a third chamber 111c having a storage capacity value between the storage capacities.

The core 110 may further include a plurality of channels 112 connected to the plurality of chambers 111 and guiding the fluid in a vertical direction.

The plurality of channels 112 includes a first channel 112a that is indirectly connected to any one of the plurality of chambers 111 and a second channel 112b that is directly connected to any one of the plurality of chambers 111 . may include

The first channel 112a is provided at a position spaced apart from the plurality of chambers 111 in the core 110 and passes through at least one flow path 120a provided in the cover 120 to be described later to the plurality of chambers 111 . can be connected to any one of them.

The second channel 112b may be directly connected to at least one of the plurality of chambers 111 and may be connected to any one of the plurality of chambers 111 through at least one flow path 120a provided in the cover 120 . have.

The storage capacity of each chamber (the first chamber 111a, the second chamber 111b, and the third chamber 111c) is the storage capacity of each chamber (the first chamber 111a, the second chamber 111b, the third chamber 111c). )) and the connected channels (the first channel 112a and the second channel 112b) may represent a value in which the storage capacity is reflected.

In addition, the core 110 may further include a third channel 112c capable of communicating with the flow path of the connector 140 coupled to the housing 130 .

When the core 110 is coupled to the housing 130 , the third channel 112c communicates with the flow path of the connector 140 , and horizontally guides the fluid introduced therein through the connector 140 . And, extending from the portion for guiding the fluid in the horizontal direction may include a portion for guiding the fluid in the vertical direction.

A plurality of third channels 112c may be provided in the core 110 .

The cover 120 is detachably coupled to the core 110 and includes at least one flow path 120a for guiding the fluid in a horizontal direction.

The at least one flow path 120a is configured to be connected to at least one of the plurality of chambers 111 or to connect at least two or more of the plurality of chambers 111 so that the storage capacity of the chamber coincides with a preset quantitative value. .

The cover 120 may be detachably coupled to the upper and lower surfaces of the core 110 , respectively.

Each cover 120 detachably coupled to the upper and lower surfaces of the core 110 is detachably coupled to the outer surface of the core 110, and a first cover member 121 including at least one flow path 120a. and a second cover member 122 detachably coupled to the outer surface of the first cover member 121 .

In addition, the cover 120 may further include an air outlet 124 .

The air outlet 124 may be formed through the first cover member 121 and the second cover member 122 so as to communicate with any one of the plurality of chambers 111 or any one of the plurality of channels 112 . have.

The housing 130 is formed in a frame structure having an accommodating space therein, and is configured to accommodate the core 110 therein.

The housing 130 includes a first part 131 supporting the lower surface of the core 110 and a second part 132 coupled to the upper side of the first part 131 to support the outer surface of the core 110 . can be

The first part 131 and the second part 132 may include a plurality of support grooves 130a for supporting the outer surface of the connector 140 .

The plurality of support grooves 130a may be provided in the first part 131 and the second part 132, respectively, and may be disposed to face each other. Accordingly, when the first part 131 and the second part 132 are coupled, the connecting body 140 accommodated between the first part 131 and the second part 132 is provided with a plurality of support grooves ( 130a) and may be stably fixed.

The first part 131 and the second part 132 may be coupled to each other through magnetism.

For example, when the first part 131 and the second part 132 are coupled, a magnetic material (not shown) may be provided at a portion where the first part 131 and the second part 132 come into contact with each other. However, the first part 131 and the second part 132 are not necessarily coupled only through a magnetic material, and may be coupled to each other through various methods.

The housing 130 may further include a coupling part (not shown) for connecting the present modular fluid chip 400 to other modular fluid chips (not shown) in various directions and at various angles.

Illustratively, the coupling portion may include at least one protrusion provided on the outer surface of the housing 130 and at least one receiving groove.

The at least one protrusion and the at least one accommodating groove may be formed in a shape corresponding to each other, and may be alternately arranged along the circumference of the housing 130 .

The connector 140 may be accommodated and supported in the housing 130 , and may be formed in the form of a tube having a flow path therein to be connected to the third channel 112c of the core 110 .

Therefore, when the present modular fluid chip 400 is connected to another modular fluid chip (not shown), the connector 140 is the core 110 of the present modular fluid chip 400 and another modular fluid chip. Cores (not shown) may communicate with each other.

The connector 140 may be formed of an elastic material, and may form an interface at the contact portion when in contact with another object. For example, the connector 140 may be formed of an elastomer material.

Hereinafter, a modular fluid chip 500 according to a fifth embodiment of the present invention will be described.

For reference, for each configuration for describing the modular fluid chip 500 according to the fifth embodiment of the present invention, for convenience of description, the modular fluid chip 100 according to the first to fourth embodiments of the present invention. , 200, 300, and 400), the same reference numerals are used, and the same or overlapping descriptions will be omitted.

9 is a plan view showing a modular fluid chip according to a fifth embodiment of the present invention, and FIG. 10 is a cross-sectional view taken along line X - X of FIG. 9 .

9 and 10 , the modular fluid chip 500 includes a core 110 , a cover 120 , a housing 130 , and a connector 140 .

The core 110 includes at least one core cell 110a and at least one dummy cell 110b.

At least one core cell 110a and at least one dummy cell 110b may be formed to have the same size. In addition, each of the core cell 110a and the dummy cell 110b may be formed to have a size of 1/n of the entire size of the core 110 . Illustratively, in this embodiment, the core cell 110a and the dummy cell 110b are each formed to have a size of 1/6 of the total size of the core 110 , and the four core cells 110a and Although the two dummy cells 110b are shown in a coupled state, the size and quantity of the core cell 110a and the dummy cell 110b are not necessarily limited thereto, and may be changed to various sizes and quantities.

Accordingly, one core 110 may be formed through a combination of at least one core cell 110a and at least one dummy cell 110b or may be formed through a combination of a plurality of core cells 110a.

At least one core cell 110a is provided on one side of the chamber 111 and the chamber 111 having a preset storage capacity, and a channel ( 112) may be included.

At least one dummy cell 110b is provided in a solid shape in which a fluid cannot be stored therein, and when coupled to the housing 130, supports the plurality of core cells 110a to align the plurality of core cells 110a. can do it

Through this, the core 110 is not newly manufactured according to the quantitative value of the set fluid, but the core cell 110a including the chamber 111 and the channel 112 and the solid dummy cell 110b are combined. By installing in the housing 130, it is possible to remove a dead volume (dead volume) and reduce the manufacturing cost.

The channel 112 provided in each core cell 110a may be connected to another chamber 111 through at least one flow path 120a provided in a cover 120 to be described later, and a chamber ( The storage capacity of 111 may represent a value in which the storage capacity of the channel 112 connected to the chamber 111 is reflected.

The channel 112 may include a first channel 112a that is indirectly connected to the chamber 111 and a second channel 112b that is directly connected to the chamber 111 .

The first channel 112a may be provided at a position spaced apart from the plurality of chambers 111 in the core cell 110a and may be connected to the chamber 111 through the flow path 120a provided in the cover 120 .

The second channel 112b may be directly connected to the chamber 111 and may be connected to the chamber 111 provided in another core cell 110a through at least one flow path 120a provided in the cover 120 .

In addition, the core cell 110a may further include a third channel 112c capable of communicating with the flow path of the connector 140 coupled to the housing 130 .

The third channel 112c communicates with the flow path of the connector 140 when the core cell 110a is coupled to the housing 130 to horizontally guide the fluid introduced therein through the connector 140 . It may include a portion and a portion extending from the portion for guiding the fluid in the horizontal direction to guide the fluid in the vertical direction.

The cover 120 is detachably coupled to the core cell 110a and includes at least one flow path 120a for guiding the fluid in vertical and horizontal directions.

At least one flow path 120a is configured to connect the plurality of core cells 110a to each other.

The cover 120 may be detachably coupled to the upper and lower surfaces of the core cell 110a, respectively.

Each cover 120 detachably coupled to the upper and lower surfaces of the core cell 110a is detachably coupled to the outer surface of the core cell 110a, and is connected to the chamber 111 and the channel 112 to provide fluids. A third cover member 126 including at least one first flow path 120a1 for guiding in the vertical direction, is detachably coupled to the outer surface of the third cover member 126, and at least one first flow path 120a1 The first cover member 121 including at least one second flow path 120a2 connected to and guiding the fluid in the horizontal direction, and a second cover member detachably coupled to the outer surface of the first cover member 121 ( 122). In addition, the cover 120 may further include an air outlet 124.

The housing 130 is configured to have a frame structure having an accommodating space therein, and to accommodate at least one core cell 110a and at least one dummy cell 110b inside.

The housing 130 includes a first part 131 supporting the lower surface of the core 110 and a second part 132 coupled to the upper side of the first part 131 to support the outer surface of the core 110 . can be The first part 131 and the second part 132 may include a plurality of support grooves 130a for supporting the outer surface of the connector 140 .

The housing 130 may further include a coupling part (not shown) for connecting the present modular fluid chip 500 to other modular fluid chips (not shown) in various directions and at various angles.

The coupling part may include at least one protrusion provided on the outer surface of the housing 130 and at least one receiving groove.

The at least one protrusion and the at least one accommodating groove may be formed in a shape corresponding to each other, and may be alternately arranged along the circumference of the housing 130 .

The connector 140 may be accommodated and supported in the housing 130 , and may be formed in the form of a tube having a flow path therein to be connected to the third channel 112c of the core 110 .

Accordingly, when the present modular fluid chip 500 is connected to another modular fluid chip (not shown), the connector 140 is the core 110 of the present modular fluid chip 500 and another modular fluid chip. Cores (not shown) may communicate with each other.

The connector 140 may be formed of an elastic material, and may form an interface at the contact portion when in contact with another object. For example, the connector 140 may be formed of an elastomer material.

Hereinafter, a modular fluid chip 600 according to a sixth embodiment of the present invention will be described.

For reference, for each configuration for describing the modular fluid chip 600 according to the sixth embodiment of the present invention, for convenience of description, the modular fluid chip 100 according to the first to fifth embodiments of the present invention. , 200, 300, 400, 500), the same reference numerals are used to describe them, and the same or overlapping descriptions will be omitted.

11 is a perspective view illustrating a modular fluid chip according to a sixth embodiment of the present invention, and FIG. 12 is an exploded perspective view of FIG. 11 .

11 and 12 , the modular fluid chip 600 includes at least one core 110 and a base 120 to which the at least one core 110 is coupled.

The core 110 has at least one chamber 111 having an individually preset storage capacity and at least one channel 112 connected to the at least one chamber 111 .

The core 110 is formed in the form of a module detachable from the base 120 .

Accordingly, at least one core 110 may be coupled to the base 120 according to a set quantitative value, and through this, the core 110 is not newly manufactured, thereby reducing manufacturing cost.

Although not shown in the drawings, an air outlet (not shown) may be further provided in the core 110 .

The base 120 is coupled to the core 110 and has at least one flow path 120a configured to be connected to the at least one chamber 111 . At least one flow path 120a may guide the fluid introduced therein in a horizontal direction.

For example, a coupling groove 120b into which an end of the core 110 is inserted may be provided on the upper surface of the base 120 . Through this, the core 110 coupled to the coupling groove 120b may be more stably maintained on the upper surface of the base 120 . In addition, the base 120 may be provided in the form of a substrate accommodated inside the housing 130 to be described later.

In addition, the modular fluid chip 600 may further include a housing 130 and a connector 140 .

The housing 130 is formed in a frame structure in which an accommodating space is formed to accommodate the base 120 inside.

The housing 130 may include a first part 131 supporting a lower surface of the base 120 and a second part 132 coupled to an upper side of the first part 131 .

The first part 131 and the second part 132 may include a plurality of support grooves 130a for supporting the outer surface of the connector 140 .

The first part 131 and the second part 132 may be coupled to each other through magnetism.

The housing 130 may further include a coupling part (not shown) for connecting the present modular fluid chip 600 to other modular fluid chips (not shown) in various directions and at various angles.

The coupling part may include at least one protrusion provided on the outer surface of the housing 130 and at least one receiving groove.

The at least one protrusion and the at least one accommodating groove may be formed in a shape corresponding to each other, and may be alternately arranged along the circumference of the housing 130 .

The connector 140 may be accommodated and supported in the housing 130 , and may be formed in the form of a tube having a flow path therein to be connected to the flow path 120a of the base 120 .

Accordingly, when the present modular fluid chip 600 is connected to another modular fluid chip (not shown), the connector 140 may communicate the present modular fluid chip 600 and another modular fluid chip with each other. .

The connector 140 may be formed of an elastic material, and may form an interface at the contact portion when in contact with another object. For example, the connector 140 may be formed of an elastomer material. As such, according to the embodiment of the present invention, at least one or two or more of the plurality of chambers 111 provided in the core 110 are connected according to the set quantitative value using the detachable cover 120 on the outer surface of the core 110 . By doing so, it is possible to create various storage spaces, and through this, it is possible to quantify liquids of various capacities through one fluid chip.

In addition, as liquid quantification of various capacities is possible through a single fluid chip, cost can be reduced.

In addition, by forming the fluid chip in the form of a module, it is possible to independently perform a preset function or to be connected to another modular fluid chip to implement a single fluid system to which various functions are complexly applied.

In addition, when applied to a fluid system, even when a specific part is deformed or damaged, only the modular fluid chip of the corresponding part can be replaced, so that management is easy and cost can be reduced.

In the above, preferred embodiments of the present invention have been illustrated and described, but the present invention is not limited to the specific embodiments described above, and it is common in the technical field to which the present invention pertains without departing from the gist of the present invention as claimed in the claims. Various modifications are possible by those having the knowledge of, of course, and these modifications should not be individually understood from the technical spirit or prospect of the present invention.

100, 200, 300, 400, 500, 600. Modular Fluid Chip
110. Core
110a. core cell
110b. dummy cell
111. Chamber
111a. first chamber
111b. second chamber
111c. third chamber
112. Channel
112a. 1st channel
112b. second channel
112c. 3rd channel
120. Cover, base
120a. Euro
120a1. 1st Euro
120a2. 2nd Euro
120b. mating groove
121. First cover member
122. Second cover member
123. Fluid inlet
124. Air outlet
125. Connection channel
125a. 1st connection channel
125b. 2nd connection channel
125c. 3rd connection channel
125d. 4th connection channel
126. Third cover member
130. Housing
130a. support groove
131. Part 1
132. Part 2
140. Linkage
150. Air filter
160. Fluid detection sensor
170. On-off valve

Claims (18)

A modular fluid chip comprising:
a core including a plurality of chambers and a plurality of channels connected to the plurality of chambers and guiding a fluid filled therein in a first direction; and
a cover coupled to the core and connected to at least one of the plurality of chambers or including at least one flow path configured to connect at least two or more of the plurality of chambers; including,
The cover is
coupled to the upper surface of the core, connecting an upper portion of any one of the plurality of chambers and any one of the plurality of channels, or connecting between the plurality of channels, and discharging the fluid introduced from the upper side of the core an upper cover configured to guide in a second direction different from the first direction; Wow,
a lower cover coupled to a lower surface of the core, connecting a lower portion of any one of the plurality of chambers and any one of the plurality of channels, and configured to guide the fluid introduced from the lower side of the core in the second direction;
A modular fluid chip comprising a. According to claim 1,
The plurality of channels,
a first channel provided at a location spaced apart from the plurality of chambers and connectable to the at least one flow path; and
a second channel connected to at least one of the plurality of chambers and connectable to the at least one flow path;
A modular fluid chip further comprising a. The modular fluid chip of claim 2 , wherein the storage capacity of each chamber represents a value reflecting the storage capacity of a channel connected to each chamber. 3. The method of claim 2,
The first channel and the second channel are provided in a smaller volume compared to the plurality of chambers modular fluid chip. According to claim 1,
The core is a modular fluid chip manufactured integrally through 3D printing or in the form of a plurality of modules that can be combined and separated through injection molding. According to claim 1,
The at least one flow path is a modular fluid chip for connecting the plurality of chambers to each other so that the fluid can be filled in order of increasing storage capacity. According to claim 1,
The cover is a modular fluid chip provided in the form of a detachable film on the outer surface of the core. 8. The method of claim 7,
The cover is
a first cover member detachable from the outer surface of the core and having the at least one flow path provided therein; and
a second cover member attached to the outer surface of the first cover member and configured to prevent the fluid filled in the at least one flow path from flowing out to an external space;
A modular fluid chip comprising a. According to claim 1,
The cover is
a fluid inlet connected to a first chamber to be filled with a fluid first among the plurality of chambers connected to the at least one flow path and into which the fluid is injected; and
an air outlet connected to a second chamber to be filled with a fluid last among the plurality of chambers connected to the at least one flow path, and through which air in the plurality of chambers is discharged when the fluid is filled in the plurality of chambers;
A modular fluid chip comprising a. 10. The method of claim 9,
An air filter installed at the air outlet and capable of removing air bubbles from the fluid;
A modular fluid chip further comprising: 11. The method of claim 10,
The air filter is a modular fluid chip provided with a hydrophobic material capable of removing air bubbles from a hydrophilic fluid. 12. The method of claim 11,
The air filter is a modular fluid provided with one or more hydrophobic materials selected from the group consisting of polytetrafluore ethylene (PTFE), polyethylene terephtalate (PET), and polyvinyl chloride (Polyvinyl Chloride). chip. 11. The method of claim 10,
The air filter is a modular fluid chip provided with a hydrophilic material capable of removing the air bubbles from the hydrophobic fluid. 11. The method of claim 10,
The air filter is a modular fluid chip in which a hydrophobic material is provided on one surface and a hydrophilic material is provided on the other surface to remove air bubbles from a mixed fluid in which a hydrophilic fluid and a hydrophobic fluid are mixed. 10. The method of claim 9,
a fluid sensor for detecting the fluid and generating it as an electrical signal; and
an opening/closing valve configured to open and close the fluid inlet according to the presence or absence of the electrical signal;
A modular fluid chip further comprising a. 11. The method of claim 10,
The cover is
a first connection channel connecting the fluid inlet and the first chamber to each other and guiding the fluid injected through the fluid inlet to the first chamber;
a second connection channel branched from the first connection channel to connect the external space and the first chamber to each other, and to guide the fluid flowing inward through the first chamber to the external space;
a third connection channel connecting the air outlet and the second chamber to each other and guiding the fluid filled in the second chamber to the air outlet; and
a fourth connection channel branched from the third connection channel to connect the external space and the second chamber, and guide air injected from the outside to the second chamber;
A modular fluid chip comprising a. A modular fluid chip comprising:
a plurality of chambers, a core connected to the plurality of chambers and including a plurality of channels for guiding a fluid filled therein; and
a cover coupled to the upper and lower surfaces of the core, respectively, and connected to at least one of the plurality of chambers, or including at least one flow path configured to connect at least two or more of the plurality of chambers;
includes,
The plurality of chambers,
a first chamber, a second chamber having a storage capacity smaller than the first chamber, and a third chamber having a storage capacity smaller than the first chamber and larger than the second chamber,
The cover is
It further comprises a fluid inlet connected to the first chamber to be filled with the fluid for the first time among the plurality of chambers connected to the at least one flow path and into which the fluid is injected,
The fluid injected through the fluid inlet may be sequentially filled in the plurality of chambers through the at least one flow path and a plurality of channels. A modular fluid chip comprising:
a core including a core cell having at least one chamber and a dummy cell provided in a solid shape; and
A first cover member coupled to the upper and lower surfaces of the core cell, respectively, and including at least one first flow path for guiding a fluid;
a second cover member detachably coupled to the outer surface of the first cover member and including at least one second flow path connected to the at least one first flow path; and
a cover including a third cover member detachably coupled to an outer surface of the second cover member;
A modular fluid chip comprising a.

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