KR102307276B1 - Ｔａｔｋ―ｃｄｋｌ５ 융합 단백질, 그의 조성물, 제형 및 용도 - Google Patents
Ｔａｔｋ―ｃｄｋｌ５ 융합 단백질, 그의 조성물, 제형 및 용도 Download PDFInfo
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- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- C12N9/10—Transferases (2.)
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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- C—CHEMISTRY; METALLURGY
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- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
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- C—CHEMISTRY; METALLURGY
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- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/405—Cell cycle regulated proteins, e.g. cyclins, cyclin-dependant kinases
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| PCT/IB2015/000999 WO2015128746A2 (en) | 2014-02-28 | 2015-02-27 | Tatk-cdkl5 fusion proteins, compositions, formulations, and use thereof |
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| KR20170002372A KR20170002372A (ko) | 2017-01-06 |
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| SG10202000537RA (en) * | 2014-02-28 | 2020-03-30 | Univ Bologna Alma Mater Studiorum | Tatk-cdkl5 fusion proteins, compositions, formulations, and use thereof |
| WO2018005617A2 (en) * | 2016-06-28 | 2018-01-04 | Alma Mater Studiorum - Universitá Di Bologna | TATĸ-CDKL5 FUSION PROTEINS, COMPOSITIONS, FORMULATIONS, AND USE THEREOF |
| TW201927825A (zh) * | 2017-11-30 | 2019-07-16 | 美商阿米庫斯醫療股份有限公司 | Cdkl5 表現變體和cdkl5 融合蛋白 |
| EP4028413A1 (en) | 2019-09-10 | 2022-07-20 | Obsidian Therapeutics, Inc. | Ca2-il15 fusion proteins for tunable regulation |
| WO2021087282A1 (en) * | 2019-10-30 | 2021-05-06 | Amicus Therapeutics, Inc. | Recombinant cdkl5 proteins, gene therapy and production methods |
| IT202000025423A1 (it) * | 2020-10-27 | 2022-04-27 | Ulisse Biomed S P A | Uso di proteine per il trattamento di patologie associate a tossine formanti pori o a proteine virali |
| AU2021392642A1 (en) | 2020-12-01 | 2023-06-22 | The Trustees Of The University Of Pennsylvania | Compositions and uses thereof for treatment of angelman syndrome |
| WO2025050032A1 (en) * | 2023-08-31 | 2025-03-06 | Ultragenyx Pharmaceutical Inc. | Methods of producing cdkl5 proteins and uses of the same |
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| SG10202000537RA (en) * | 2014-02-28 | 2020-03-30 | Univ Bologna Alma Mater Studiorum | Tatk-cdkl5 fusion proteins, compositions, formulations, and use thereof |
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| Molecular Therapy, 2008, Vol.17, No.2, pp.334-342 |
| The Journal of Neuroscience, 2010, Vol.30, No.38, pp.12777-12786 |
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