KR102259589B9 - 미소구체 제조 시스템 및 미소구체 제조 방법 - Google Patents
미소구체 제조 시스템 및 미소구체 제조 방법Info
- Publication number
- KR102259589B9 KR102259589B9 KR20200164614A KR20200164614A KR102259589B9 KR 102259589 B9 KR102259589 B9 KR 102259589B9 KR 20200164614 A KR20200164614 A KR 20200164614A KR 20200164614 A KR20200164614 A KR 20200164614A KR 102259589 B9 KR102259589 B9 KR 102259589B9
- Authority
- KR
- South Korea
- Prior art keywords
- microsphere
- manufacturing
- manufacturing system
- microsphere manufacturing
- manufacturing microsphere
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 2
- 239000004005 microsphere Substances 0.000 title 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
- B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
- B01F33/812—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more alternative mixing receptacles, e.g. mixing in one receptacle and dispensing from another receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Colloid Chemistry (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020200164614A KR102259589B1 (ko) | 2020-11-30 | 2020-11-30 | 미소구체 제조 시스템 및 미소구체 제조 방법 |
KR1020210067548A KR102484787B1 (ko) | 2020-11-30 | 2021-05-26 | 미소구체 제조 시스템 |
CN202180079270.4A CN117202892A (zh) | 2020-11-30 | 2021-08-02 | 微球体制造系统和微球体制造方法 |
PCT/KR2021/010078 WO2022114450A1 (ko) | 2020-11-30 | 2021-08-02 | 미소구체 제조 시스템 및 미소구체 제조 방법 |
US18/038,535 US20240016742A1 (en) | 2020-11-30 | 2021-08-02 | Microsphere producing system and microsphere producing method |
JP2023532784A JP2023551321A (ja) | 2020-11-30 | 2021-08-02 | 微小球体の製造システムおよび微小球体の製造方法 |
EP21898279.1A EP4252900A4 (en) | 2020-11-30 | 2021-08-02 | SYSTEM FOR PRODUCING MICROBEADS AND METHOD FOR PRODUCING MICROBEADS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020200164614A KR102259589B1 (ko) | 2020-11-30 | 2020-11-30 | 미소구체 제조 시스템 및 미소구체 제조 방법 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020210067548A Division KR102484787B1 (ko) | 2020-11-30 | 2021-05-26 | 미소구체 제조 시스템 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR102259589B1 KR102259589B1 (ko) | 2021-06-02 |
KR102259589B9 true KR102259589B9 (ko) | 2021-08-23 |
Family
ID=76372804
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020200164614A KR102259589B1 (ko) | 2020-11-30 | 2020-11-30 | 미소구체 제조 시스템 및 미소구체 제조 방법 |
KR1020210067548A KR102484787B1 (ko) | 2020-11-30 | 2021-05-26 | 미소구체 제조 시스템 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020210067548A KR102484787B1 (ko) | 2020-11-30 | 2021-05-26 | 미소구체 제조 시스템 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20240016742A1 (ko) |
EP (1) | EP4252900A4 (ko) |
JP (1) | JP2023551321A (ko) |
KR (2) | KR102259589B1 (ko) |
CN (1) | CN117202892A (ko) |
WO (1) | WO2022114450A1 (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102259589B1 (ko) * | 2020-11-30 | 2021-06-02 | (주)인벤티지랩 | 미소구체 제조 시스템 및 미소구체 제조 방법 |
KR102386163B1 (ko) * | 2021-12-03 | 2022-04-14 | (주)인벤티지랩 | 류프로라이드를 포함하는 마이크로 입자 및 이의 제조 방법 |
KR102431191B1 (ko) * | 2021-12-22 | 2022-08-11 | (주)인벤티지랩 | 미소구체 제조 장치 및 미소구체 제조 방법 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1688275B (zh) | 2002-09-11 | 2012-05-30 | 田边三菱制药株式会社 | 微球的制备方法 |
JP5377862B2 (ja) * | 2007-01-26 | 2013-12-25 | 三洋化成工業株式会社 | 単分散微粒子の製造法 |
KR20130047232A (ko) * | 2011-10-31 | 2013-05-08 | 재단법인 전라남도생물산업진흥재단 | 초임계유체를 이용한 서방형 약물 함유 미립자의 제조방법 및 이를 이용한 의료용 스텐트의 제조방법 |
US9439864B2 (en) * | 2014-07-07 | 2016-09-13 | Antriabio, Inc. | Solvent extraction from biodegradable microparticles |
GB201622024D0 (en) * | 2016-11-14 | 2017-02-08 | Inventage Lab Inc | Apparatus and method for large scale production of monodisperse, microsheric and biodegradable polymer-based drug delivery |
KR102142026B1 (ko) * | 2017-05-31 | 2020-08-06 | 주식회사 대웅제약 | 방출제어가 용이한 서방성 약물 미립자의 제조방법 |
KR102259589B1 (ko) * | 2020-11-30 | 2021-06-02 | (주)인벤티지랩 | 미소구체 제조 시스템 및 미소구체 제조 방법 |
-
2020
- 2020-11-30 KR KR1020200164614A patent/KR102259589B1/ko active IP Right Grant
-
2021
- 2021-05-26 KR KR1020210067548A patent/KR102484787B1/ko active IP Right Review Request
- 2021-08-02 EP EP21898279.1A patent/EP4252900A4/en active Pending
- 2021-08-02 WO PCT/KR2021/010078 patent/WO2022114450A1/ko active Application Filing
- 2021-08-02 JP JP2023532784A patent/JP2023551321A/ja active Pending
- 2021-08-02 US US18/038,535 patent/US20240016742A1/en active Pending
- 2021-08-02 CN CN202180079270.4A patent/CN117202892A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CN117202892A (zh) | 2023-12-08 |
WO2022114450A1 (ko) | 2022-06-02 |
EP4252900A1 (en) | 2023-10-04 |
EP4252900A4 (en) | 2024-06-05 |
KR102484787B9 (ko) | 2024-04-08 |
KR20220076269A (ko) | 2022-06-08 |
KR102259589B1 (ko) | 2021-06-02 |
US20240016742A1 (en) | 2024-01-18 |
JP2023551321A (ja) | 2023-12-07 |
KR102484787B1 (ko) | 2023-01-05 |
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Legal Events
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AMND | Amendment | ||
X091 | Application refused [patent] | ||
AMND | Amendment | ||
X701 | Decision to grant (after re-examination) | ||
A107 | Divisional application of patent | ||
GRNT | Written decision to grant | ||
G170 | Re-publication after modification of scope of protection [patent] |