KR102119568B1 - A compound for preventing hair loss and promoting hair growth - Google Patents

Abstract

Disclosed is a composition for preventing hair loss and promoting hair growth and a method for manufacturing the same. The composition for preventing hair loss and promoting hair growth is prepared through a hot water extraction method, and promotes hair growth in the scalp, and exhibits excellent hair loss prevention and hair growth promotion efficacy in an actual human application test for alopecia patients.

Description

Composition for preventing hair loss and promoting hair growth{A COMPOUND FOR PREVENTING HAIR LOSS AND PROMOTING HAIR GROWTH}

The present invention relates to a composition for preventing hair loss and promoting hair growth and a method for preparing the composition.

Human heads usually have an average of around 100,000 hairs, which repeat their production and disappearance with periodic changes in anagen, catagen, telogen, and hair loss. Hair is composed of 90% keratin composed of 18 amino acids and 10% moisture as a basic component, and the constituent elements consist of carbon, oxygen, nitrogen, hydrogen, and sulfur.

Human hair is formed in hair follicles. The hair follicle has a papilla, where small blood vessels are distributed to supply nutrients necessary for hair growth, and the sebaceous glands secreting sebum to protect the hair are distributed on the upper side of the hair nipple. The breast nipple is a place that controls the growth of hair, and is also the site where male hormones act in male pattern hair loss. The area where cell division occurs according to the regulation in the papilla is the site where the hair is generated and the hair is produced.

The most well-known hair loss factor for men is the effect of abnormal hormones. In puberty, sex hormones are actively secreted and secondary sexual characteristics appear. These changes are caused by the sex hormones androgens (male hormones) and estrogens (female hormones). Androgen develops hair from the eyebrows down, and estrogen primarily promotes hair growth. In men, baldness is because androgens are over-secreted, and over-secreted androgens inhibit the action of estrogen.

Looking more closely at the mechanism of male hair loss caused by testosterone, testosterone, one of the testosterone, is an active testosterone dihydrotestosterone by an enzyme called 5 alpha-reductase (5a-reductase). The converted and thus activated hormone binds to the androgen receptor and delays the protein synthesis of hair follicle cells, resulting in a shortening of the hair growth period.

Relatively, the frequency of hair loss in the same mechanism is considerably lower than that of men, because women have only half of 5-alpha-reductase compared to men. In addition, women have a lot of enzymes called aromatase. This aromatase is particularly distributed near the hairline of the bangs and inhibits the production of dihydrotestosterone. For this reason, female hair loss appears differently from men. In general, women have little androgen hormone levels, so they rarely develop into bald, bald, foreheads like men. Female hair loss is generally known to have a stronger genetic predisposition, but the presence or absence of expression is influenced by male hormones.

In modern society, various oxidative stress is particularly caused by various pollutants, physical stimulating factors, excessive smoking, drinking, and stress. According to a recent study report, when chemically induced oxidative stress is applied to the scalp, excessive oxidative stress may convert growth hair into a resting period, and variously worsen the hair condition, which may cause hair loss. In addition, it is known that oxidative stress is a mechanism for activating the type 2 beta-corticocortin secreting hormone receptor around the hair follicle and may cause alopecia areata. In addition, as one of the major causes of damaged hair, oxidative stress caused by contaminants such as air pollution and dandruff caused by the transition of abnormal dandruff bacteria may include unclean scalp conditions.

As attempted in recent patents, in the case of a composition using herbal herbal medicine, it is necessary to precede safety testing in order to safely use it when applied to the human body with systematic and scientific efficacy evaluation for hair loss prevention and hair growth.

In this regard, Republic of Korea Patent Registration No. 10-1835973 discloses a composition for preventing hair loss and promoting hair growth using herbal medicines and a method for manufacturing the same.

The present invention has been devised to solve the aforementioned problems, and an embodiment of the present invention provides a composition for preventing hair loss and promoting hair growth.

In addition, an embodiment of the present invention provides a method for preparing the composition for preventing hair loss and promoting hair growth.

The technical problems to be achieved by the present invention are not limited to the technical problems mentioned above, and other technical problems not mentioned can be clearly understood by those having ordinary knowledge in the technical field to which the present invention belongs from the following description. There will be.

As a technical means for achieving the above-described technical problem, one aspect of the present invention,

A first extract of hot water extracted by mixing red pepper and yangje root; A second extract of hot water extracted by mixing purslane and grafted alley; And a third extract extracted by mixing hot water by mixing pumpkin, cucumber, and pineapple; and the content of the first extract compared to 100 parts by weight is 40 parts by weight to 80 parts by weight, and the content of the second extract is 10 parts by weight to 30 parts by weight, the content of the third extract is 10 parts by weight to 30 parts by weight, which provides a composition for preventing hair loss and promoting hair growth.

The first extract may further include an extract of a substance selected from the group consisting of Eoseongcho, snail, coffee, Hannyeoncho and combinations thereof.

The first extract may further include an extract of a substance selected from the group consisting of jujube, jujube, bone crush, Angelica, Baekbokryeong, safflower, health, geonjihwang, hyanggak, red peony, and a combination of these.

The second extract may further include an extract of a substance selected from the group consisting of Baegamjam, dandelion, and combinations thereof.

The second extract may further include an extract of a substance selected from the group consisting of Woogak, Gosam, Burdock, Peppermint, Dansam, Countess, Creation, Changja, Rhubarb, Pine Needle and combinations thereof.

The third extract may further include an extract of a substance selected from the group consisting of dandelion, eggplant, uiin, dansam, lotus, licorice, celestial, mung bean, shiitake, and combinations thereof.

The content of the dripping sewage or Yangje root relative to 100 parts by weight of the first extract may be 10 parts by weight to 30 parts by weight.

The content of the purslane or grafted tree compared to 100 parts by weight of the second extract may be 15 parts by weight to 40 parts by weight.

The content of the pumpkin, cucumber, or pickle compared to 100 parts by weight of the third extract may be 10 parts by weight to 30 parts by weight.

In addition, another aspect of the present invention,

Crushing the first natural product group including dripping sorghum and yangjaegeun, the second natural product group including purslane and graft, and the third natural product group including pumpkin, cucumber, and gall; Preparing a first extract, a second extract, and a third extract by hot-water extraction of the pulverized first natural product group, second natural product group, and third natural product group, respectively; And mixing the prepared first extract, second extract, and third extract; the content of the first extract compared to 100 parts by weight in total is 40 parts by weight to 80 parts by weight, and the content of the second extract Silver 10 parts by weight to 30 parts by weight, the content of the third extract is mixed with 10 parts by weight to 30 parts by weight, provides a method for preparing a composition for preventing hair loss and promoting hair growth.

The hot water extraction may be performed at 50 ℃ to 100 ℃.

The hot water extraction may be performed for 15 hours to 45 hours.

According to an embodiment of the present invention, the composition for preventing hair loss and promoting hair growth is prepared through a hot water extraction method, promotes hair growth in the scalp, prevents excellent hair loss in a real human application test for alopecia patients, and It shows the effect of promoting hair growth.

According to an embodiment of the present invention, the composition for preventing hair loss and promoting hair growth exhibits a high rate of dandruff reduction in addition to promoting hair growth, and also has an excellent effect of removing scalp itchiness and efficacy of moisturizing hair.

It should be understood that the effects of the present invention are not limited to the above-described effects, and include all effects that can be deduced from the configuration of the invention described in the detailed description or claims of the present invention.

1 is a schematic view showing a method of manufacturing a composition for preventing hair loss and promoting hair growth according to an embodiment of the present invention.

Hereinafter, the present invention will be described in more detail. However, the present invention may be implemented in various different forms, and the present invention is not limited by the examples described herein, and the present invention is only defined by the claims below.

In addition, the terms used in the present invention are only used to describe specific embodiments, and are not intended to limit the present invention. Singular expressions include plural expressions unless the context clearly indicates otherwise. 'Including' a component throughout the specification of the present invention means that other components may be further included instead of excluding other components, unless otherwise stated.

The first aspect of the present application,

A first extract of hot water extracted by mixing red pepper and yangje root; A second extract of hot water extracted by mixing purslane and grafted alley; And a third extract extracted by mixing hot water by mixing pumpkin, cucumber, and pineapple; and the content of the first extract compared to 100 parts by weight is 40 parts by weight to 80 parts by weight, and the content of the second extract is 10 parts by weight to 30 parts by weight, the content of the third extract is 10 parts by weight to 30 parts by weight, which provides a composition for preventing hair loss and promoting hair growth.

Hereinafter, the compound represented by Formula 1 according to the first aspect of the present application or a pharmaceutically acceptable salt thereof will be described in detail.

In one embodiment of the present application, the first extract may include an extract of a substance that is effective in preventing hair loss and promoting hair growth.

In one embodiment of the present application, the content of the first extract compared to 100 parts by weight of the composition for preventing hair loss and promoting hair growth may be from about 40 parts by weight to about 80 parts by weight, preferably from about 50 parts by weight to about 70 parts by weight It may be parts, more preferably about 60 parts by weight, but is not limited thereto. When the content of the first extract is less than 40 parts by weight or more than 80 parts by weight, the efficacy of preventing hair loss and promoting hair growth of the composition may be reduced, but is not limited thereto.

In one embodiment of the present application, the dripping sewage (Polygonum multiflorum Thunb) is included to improve hair loss and gray hair, and can be used by drying the root portion of dripping sewage. The dropping water is a vine perennial plant belonging to the Polygonaceae family, and contains oxymethylanthraquinone derivatives such as Chrysophanol, Emodin, and Lecithin. Contains.

In one embodiment of the present application, the yangjegeun (Rumecis Radix (KHP)) is a vegetable having the nickname of the poison, which means the vegetable of the bald, particularly in the form of a disease, serves to improve alopecia due to dermatitis of the scalp.

In one embodiment of the present application, the litter means ivy growing in pine trees (Parthenocissus tricuspidata (Siebold & Zucc.) Planch.), neuralgia, diabetes, cough sputum, paralyzed by paralysis, migraine, etc. There is this.

In one embodiment of the present application, the content of the dripping sorghum or Yangje root relative to 100 parts by weight of the first extract may be from about 10 parts by weight to about 30 parts by weight, but is not limited thereto. For example, preferably, the content of the dripping sorghum or yangje root relative to 100 parts by weight of the first extract may be about 10 parts by weight to about 20 parts by weight, more preferably about 14 parts by weight to about 17 parts by weight, , But is not limited thereto.

In one embodiment of the present application, the first extract may further include an extract of a substance selected from the group consisting of eoseongcho, slobung, coffee, hannyeoncho and combinations thereof.

In one embodiment of the present application, the content of the material selected from the group consisting of Eoseongcho, snail, coffee, Hannyeoncho and combinations thereof may be from about 5 parts by weight to about 15 parts by weight compared to 100 parts by weight of the first extract However, it is not limited thereto, and may be preferably about 10 parts by weight, but is not limited thereto.

In one embodiment of the present application, the first extract is an extract of a material selected from the group consisting of jujube, jujube, golchibo, Angelica, Baekbokryeong, safflower, health, geonji, right angle, red peony, celestial, and combinations thereof. It may be further included.

In one embodiment of the present application, the content of the material selected from the group consisting of the jujube, lateral juniper leaf, golchebo, Angelica, Baekbokryeong, safflower, health, geonjihwang, right angle, peony, celestial, and combinations thereof is the first extract It may be from about 1 part by weight to about 5 parts by weight relative to 100 parts by weight, but is not limited thereto, preferably from about 2 parts by weight to about 3 parts by weight, but is not limited thereto.

In one embodiment of the present application, the baekryeop refers to the young branches and leaves of the white cypress (Thuja orientalis L.) of the Cypress family, and is effective in bleeding nosebleeds, hematopoiesis, bleeding, urine bleeding, and uterine bleeding. , Asthma, sputum, hair loss, seborrheic dermatitis, bleeding, etc. are also effective.

In one embodiment of the present application, the baekryeop refers to the rhizome of the golanchoe (Drynaria fortunei Smith: 蕨), low back pain, swaying teeth, tinnitus, molar, chronic diarrhea, vision loss, bruises, renal weakness It is effective for fracture, stagnation of blood, hair loss, and aphrodisiac.

In one embodiment of the present application, the Baekbokryeong means drying the bacterial nuclei of the Bokryeong (Poria cocas Wolf.), menopause, parenteral (심), cardiac (心經), nerve (腎經), bladder (膀胱經) acts to protect the spleen, cut sputum and stabilize the mind.

In one embodiment of the present application, the health means dried rhizome of ginger (Zingiber officinale Roscoe), and is effective for vomiting, diarrhea, and the like.

In one embodiment of the present application, the dried geonji refers to dried rhizomes of the rhizome (Rehmannia glutinosa Libosch. var. purpurea Mak.), which is the ginseng family, anemia, cow dung, hemorrhage, non-bleeding, uterine bleeding , Menstrual disorders, constipation, general weakness is effective.

In one embodiment of the present application, the red peony means the root of Paeonia genus lactiflora (= Paeonia albiflora), veitchii, etc., discharges clogged blood, stops pain, removes heat from blood, and swells the swelling effect. have.

In one embodiment of the present application, the second extract may include an extract of a substance effective for whitening.

In one embodiment of the present application, the content of the second extract compared to 100 parts by weight of the composition for preventing hair loss and promoting hair growth may be about 10 parts by weight to about 30 parts by weight, and preferably about 15 parts by weight to about 25 parts by weight It may be parts, more preferably about 20 parts by weight, but is not limited thereto. When the content of the second extract is less than 10 parts by weight or more than 30 parts by weight, the efficacy of preventing hair loss and promoting hair growth of the composition may be reduced, but is not limited thereto.

In one embodiment of the present application, the purslane (Portulaca oleracea L.) is also called marchi, rich in components of cancer such as lignin and molybdenum, acts to separate carcinogens, remove inflammation, remove itching, remove atopy It removes sexual inflammation and relieves various dermatitis, and can exhibit sebum control action and anti-allergic effect. In particular, the purslane is an herb that is surprisingly effective in treating various swelling and boils, and may also have a cleansing effect.

In one embodiment of the present application, the grafted tree (Sambucus) is a Chinese name named as a medicinal tree that is well heard when the bone is broken or sprained, as the name suggests. There are runku trees and elder trees, and all of them are characterized by ripening in red. The grafted neck strengthens the muscles and bones to prevent arthritis, discs, etc., removes blemishes and freckles, and is effective in skin whitening. In addition, washing the body with water decoction of the allograft has the effect of sinking various skin diseases such as itching, athlete's foot, eczema, and burns.

In one embodiment of the present application, the content of the purslane or grafted tree relative to 100 parts by weight of the second extract may be from about 15 parts by weight to about 40 parts by weight, but is not limited thereto. For example, preferably, the content of the purslane or grafted tree relative to 100 parts by weight of the second extract may be about 20 parts by weight to about 30 parts by weight, more preferably about 25 parts by weight to about 30 parts by weight, , But is not limited thereto.

In one embodiment of the present application, the second extract may further include an extract of a substance selected from the group consisting of white nap, dandelion and combinations thereof.

In one embodiment of the present application, the content of the material selected from the group consisting of white nap, dandelion and combinations thereof may be from about 5 parts by weight to about 15 parts by weight compared to 100 parts by weight of the second extract, but is not limited thereto. It is not, and may be preferably about 10 parts by weight, but is not limited thereto.

In one embodiment of the present application, the second extract further comprises an extract of a substance selected from the group consisting of woogak, gosam, burdock, peppermint, ginseng, county medicinal, creation, changja, rhubarb, pine needles, and combinations thereof. May be

In one embodiment of the present application, the content of the material selected from the group consisting of the right angle, gosam, burdock, peppermint, sweet ginseng, county medicinal, creation, changja, rhubarb, pine needles and combinations thereof is 100 parts by weight of the second extract It may be from about 1 part by weight to about 5 parts by weight, but is not limited thereto.

In one embodiment of the present application, the count is a root of peony (Paeonia lactiflora Pallas (Peonia and Paeoniaceae)), which means boiled and dried after removing the main skin, and is caused by hememia, abdominal pain due to blood clot, stomach pain due to gastrointestinal spasm, neuralgia, It is effective for rheumatoid arthritis, menstrual pain, chest pain, and nervous breakdown.

In one embodiment of the present application, the creation refers to the root stem of Atractylodes lancea de Candolle or Achangylodes chinensis Koidsumi (Asteraceae Compositae), which strengthens the stomach and spleen. , Warms the kidneys, eliminates fatigue and thirst, makes sweat and urine better, and has the effect of removing poison and pain in the body.

In one embodiment of the present application, the intestine refers to the fruit of the asteraceae (Xanthium strumarium L.), and is effective for sinusitis, rhinitis, headache, fever, cough, limb pain, skin itching, and otitis media.

In one embodiment of the present application, the third extract may include an extract of a substance effective for skin diseases such as atopy.

In one embodiment of the present application, the content of the third extract compared to 100 parts by weight of the composition for preventing hair loss and promoting hair growth may be about 10 parts by weight to about 30 parts by weight, preferably about 15 parts by weight to about 25 parts by weight It may be parts, more preferably about 20 parts by weight, but is not limited thereto. When the content of the third extract is less than 10 parts by weight or more than 30 parts by weight, the efficacy of preventing hair loss and promoting hair growth of the composition may be reduced, but is not limited thereto.

In one embodiment of the present application, the content of the pumpkin, cucumber, or pickle compared to 100 parts by weight of the third extract may be about 10 parts by weight to about 30 parts by weight, but is not limited thereto. For example, preferably, the content of the pumpkin, cucumber, or pickle compared to 100 parts by weight of the third extract may be about 15 parts by weight to about 25 parts by weight, more preferably about 20 parts by weight, but is not limited thereto. It is not.

In one embodiment of the present application, the third extract is to further include an extract of a substance selected from the group consisting of dandelion, eggplant, uiin, dansam, lotus, licorice, celestial, mung bean, shiitake mushrooms and combinations thereof. Can be.

In one embodiment of the present application, the content of a material selected from the group consisting of the dandelion, eggplant, uiin, dansam, lotus, licorice, celestial, mung bean, shiitake and combinations thereof is 100 parts by weight of the third extract It may be from about 1 part by weight to about 10 parts by weight, but is not limited thereto, preferably from about 4 parts by weight to about 5 parts by weight, but is not limited thereto.

e var. ma-yuen Stapf(벼과 Gramineae))의 잘 익은 씨로서 씨껍질을 제거한 것을 뜻하며, 부종, 배뇨 장애, 각기, 비허에 의한 설사, 폐농양, 급성 충수염, 대하증 등에 효능이 있다.In one embodiment of the present application, the right person is Yulmu (Coix lacryma-jobi Linn)

e var. It is a ripe seed of ma-yuen Stapf (Rice and Gramineae), which means that the peel has been removed, and it is effective in edema, urination disorders, each, diarrhea caused by unlicensed, lung abscess, acute appendicitis, hypothalamus, etc.

In one embodiment of the present application, the bridge refers to the dried fruit of the Forsythia viridissima Lindley or Forsythia suspensa Vahl of the Ash family, and lowers the heat in the early stage of the fever so that high fever and spirit confuse It is effective in calming down, boils, lymphadenitis, and sore throat.

The second aspect of the present application,

Crushing the first natural product group including dripping sorghum and yangjaegeun, the second natural product group including purslane and graft, and the third natural product group including pumpkin, cucumber, and gall; Preparing a first extract, a second extract, and a third extract by hot-water extraction of the pulverized first natural product group, second natural product group, and third natural product group, respectively; And mixing the prepared first extract, second extract, and third extract; the content of the first extract compared to 100 parts by weight in total is 40 parts by weight to 80 parts by weight, and the content of the second extract Silver 10 parts by weight to 30 parts by weight, the content of the third extract is mixed with 10 parts by weight to 30 parts by weight, provides a method for preparing a composition for preventing hair loss and promoting hair growth.

The detailed description of parts overlapping with the first aspect of the present application is omitted, but the description of the first aspect of the present application may be equally applied even if the description is omitted in the second aspect.

Hereinafter, a method for preparing a composition for preventing hair loss and promoting hair growth according to the second aspect of the present application will be described in detail step by step with reference to FIG. 1.

First, in one embodiment of the present application, the method for preparing the composition for preventing hair loss and promoting hair growth includes a first natural product group including dripping sewage and yangseogeun, a second natural product group including purslane and grafted bone, pumpkin, cucumber, and It may include a step (S100) of crushing each of the third group of natural products containing litter.

In one embodiment of the present application, the pulverization method is not particularly limited, and a method capable of pulverizing to a size as small as possible so that a large amount of the hair growth active ingredient contained in the natural product can be eluted by hot water extraction may include all. .

In one embodiment of the present application, the first group of natural products is Eoseongcho, snail, coffee, Hannyeoncho, jujube, jujube, ginsengbo, Angelica, Baekbokryeong, safflower, health, geonji, woogak, red peony, celestial, and combinations thereof It may further include a material selected from the group consisting of.

In one embodiment of the present application, the second group of natural products is a material selected from the group consisting of Baegamjam, Dandelion, Woogak, Gosam, Burdock, Peppermint, Dansam, Peony, Creation, Changja, Rhubarb, Pine Needle, and combinations thereof. It may be further included.

In one embodiment of the present application, the third natural product group may further include a material selected from the group consisting of dandelion, eggplant, ui-in, dansam, lotus, licorice, celestial, mung bean, shiitake, and combinations thereof. have.

Next, in one embodiment of the present application, the method for preparing the composition for preventing hair loss and promoting hair growth is obtained by first extracting hot water from the pulverized first natural product group, the second natural product group, and the third natural product group, respectively, to extract the first extract, It may include a step (S200) for preparing a second extract and a third extract.

In one embodiment of the present application, the hot water extraction method uses distilled water as a solvent, and there is no particular limitation when the extraction rate of the bioactive substance contained in the natural product is high, and increases the concentration of the hair growth active ingredient obtained by the hot water extraction. In order to reduce the amount of distilled water as a solvent or to increase the amount of the natural product, it may be extracted, but is not limited thereto.

In one embodiment of the present application, the hot water extraction method may use a heating high pressure extraction method or a heating reflux extraction method, and the hot water extraction is used for extraction because the physiologically active substance is extracted with pure hot distilled water as a solvent. It may have the advantage that the problem caused by the toxicity of the solvent does not occur, but is not limited thereto.

In one embodiment of the present application, the hot water extraction method may preferably use a heated reflux extraction method, wherein the heated reflux extraction method puts hot distilled water in a container, puts a natural product on top of the container, and then regenerates the natural product through reflux. It may be carried out so that the active ingredient is dissolved in distilled water in the container.

In one embodiment of the present application, the content of the distilled water may be about 1 L to about 3 L per 100 g, respectively, of the first natural product group, the second natural product group, and the third natural product group, but is not limited thereto. It may be about 2 L, but is not limited thereto.

In one embodiment of the present application, the hot water extraction may be performed at about 50 °C to about 100 °C, but is not limited thereto, and may preferably be performed at about 70 °C to about 100 °C, more preferably It may be carried out at about 90 ℃, but is not limited thereto. When the hot water extraction is performed at less than 50°C, the temperature of the water is too low to facilitate the hot water extraction, and when it is performed at more than 100°C, the boiled water may contain less active hair growth, but is not limited thereto.

In one embodiment of the present application, the hot water extraction may be performed for about 15 hours to about 45 hours, but is not limited thereto, and may be preferably performed for about 25 hours to about 35 hours, more preferably It may be performed for about 30 hours, but is not limited thereto. When the hot water extraction is performed for less than 15 hours, the concentration of the hair growth active ingredient contained in the extract may be significantly lower, and when it is performed for more than 45 hours, the hair growth active ingredient is already included in all of the extract, so it may not be time-efficient. However, it is not limited thereto.

In one embodiment of the present application, the content of the dripping sorghum or Yangje root relative to 100 parts by weight of the first extract may be from about 10 parts by weight to about 30 parts by weight, but is not limited thereto. For example, preferably, the content of the dripping sorghum or yangje root relative to 100 parts by weight of the first extract may be about 10 parts by weight to about 20 parts by weight, more preferably about 14 parts by weight to about 17 parts by weight, , But is not limited thereto. In addition, the content of the material selected from the group consisting of Eoseongcho, snail, coffee, Hannyeoncho and combinations thereof may be from about 5 parts by weight to about 15 parts by weight compared to 100 parts by weight of the first extract, but is not limited thereto No, it may preferably be about 10 parts by weight, but is not limited thereto. In addition, the content of the material selected from the group consisting of the jujube, side baekryeop, bone shredding, Angelica, Baekbokryeong, safflower, health, geonjihwang, woogak, red peony, and a combination of these is about 1 to 100 parts by weight of the first extract It may be from about 5 parts by weight to about 5 parts by weight, but is not limited thereto, preferably from about 2 parts by weight to about 3 parts by weight, but is not limited thereto.

In one embodiment of the present application, the content of the purslane or grafted tree relative to 100 parts by weight of the second extract may be from about 15 parts by weight to about 40 parts by weight, but is not limited thereto. For example, preferably, the content of the purslane or grafted tree relative to 100 parts by weight of the second extract may be about 20 parts by weight to about 30 parts by weight, more preferably about 25 parts by weight to about 30 parts by weight, , But is not limited thereto. In addition, the content of the material selected from the group consisting of Baekgangjam, dandelion and combinations thereof may be from about 5 parts by weight to about 15 parts by weight compared to 100 parts by weight of the second extract, but is not limited thereto, preferably It may be about 10 parts by weight, but is not limited thereto. In addition, the content of the material selected from the group consisting of the right angle, gosam, burdock, peppermint, sweet ginseng, count, changja, rhubarb, pine needles and combinations thereof is about 1 part by weight to 100 parts by weight of the second extract It may be about 5 parts by weight, but is not limited thereto.

In one embodiment of the present application, the content of the pumpkin, cucumber, or pickle compared to 100 parts by weight of the third extract may be about 10 parts by weight to about 30 parts by weight, but is not limited thereto. For example, preferably, the content of the pumpkin, cucumber, or pickle compared to 100 parts by weight of the third extract may be about 15 parts by weight to about 25 parts by weight, more preferably about 20 parts by weight, but is not limited thereto. It is not. In addition, the content of the material selected from the group consisting of the dandelion, eggplant, uiyiin, dansam, lotus, licorice, cheongung, mung bean, shiitake mushrooms and combinations thereof is about 1 part by weight to about 100 parts by weight of the third extract It may be 10 parts by weight, but is not limited thereto, preferably from about 4 parts by weight to about 5 parts by weight, but is not limited thereto.

Next, in one embodiment of the present application, the method for preparing the composition for preventing hair loss and promoting hair growth may include mixing the prepared first extract, second extract, and third extract (S300).

In one embodiment of the present application, the content of the first extract is 40 parts by weight to 80 parts by weight, and the content of the second extract is 10 parts by weight to 30 parts by weight, and the third extract compared to 100 parts by weight in total. The content of may be mixed by 10 parts by weight to 30 parts by weight, but is not limited thereto. At this time, when it exceeds the mixing ratio, the hair loss prevention and hair growth promotion efficacy of the prepared composition for preventing hair loss and hair growth may be reduced, but is not limited thereto.

In one embodiment of the present application, the composition for preventing hair loss and promoting hair growth may be mixed with natural soap and used as a soap for preventing hair loss and promoting hair growth. At this time, the natural soap is not limited to a general natural soap, and the preparation of the soap for preventing hair loss and promoting hair growth may be produced by heating the natural soap and changing it into a liquid, mixing the composition with the composition, and cooling the mixture. However, it is not limited thereto.

In one embodiment of the present application, the mixing of the liquid of the natural soap and the composition for preventing hair loss and promoting hair growth may be a mixture of about 400 L to about 800 L of the natural soap 1 kg liquid, but is not limited thereto. However, the composition is preferably about 500 L to about 600 L may be mixed, more preferably about 580 L may be mixed, but is not limited thereto.

In one embodiment of the present application, the prepared composition for preventing hair loss and promoting hair growth is not limited to the use as the soap, and there is no limitation in the useable surface for washing hair, for example, as a use for shampoo, etc. It can be used, but is not limited thereto.

Hereinafter, embodiments of the present invention will be described in detail so that those skilled in the art to which the present invention pertains can easily practice. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein.

Preparation Example 1. Preparation of composition for preventing hair loss and promoting hair growth

All natural products for the hair growth experiment of the present invention were purchased from an establishment selling medicinal herbs, or collected by the inventors themselves or purchased at a mart, and the experiment was carried out, and then crushed to about 3 to 4 cm using peanuts, and then powdered using a grinder. Secondary grinding was performed in the form, and natural products included in the first natural product group, the second natural product group, and the third natural product group were mixed with each other. The mass of the mixed first natural product group, second natural product group, and third natural product group was 100 g, respectively. Table 1 below shows the types and content ratios of the first natural product group, the second natural product group, and the third natural product group.

[Table 1]

Next, the mixed first natural product group, second natural product group, and third natural product group were respectively hot-water extracted. The hot water extraction is covered with a cloth on top of each of three containers containing distilled water (2 L) of about 90° C., and each of the first natural product group, the second natural product group and the third natural product group is placed on the cloth and sealed. Was performed for about 30 hours. About 1.8 L to about 1.9 L of the first natural product group (first extract), the second natural product group (second extract), and the third natural product group (third extract), respectively, having completed hot water extraction were obtained. Thereafter, the obtained first extract, second extract, and third extract were mixed at a ratio of 6:2:2 to prepare a composition for preventing hair loss and promoting hair growth.

Production Example 2. Preparation of soap for preventing hair loss and promoting hair growth

The composition for preventing hair loss and promoting hair growth prepared in Preparation Example 1 was mixed with natural soap to prepare a soap for preventing hair loss and promoting hair growth. For the preparation, after purchasing a general natural soap, 100 g of the natural soap was liquefied by heating. 58 L of the composition prepared in Preparation Example 1 was mixed with the liquefied natural soap, and then cooled in a mold to prepare a soap for preventing hair loss and promoting hair growth.

Experimental Example 1. Dandruff reduction rate measurement

In order to confirm the anti-dandruff efficacy of the soap for preventing hair loss and promoting hair growth (hereinafter referred to as an example soap) prepared in Preparation Example 2, 20 persons with relatively high dandruff were selected to use the Example Soap for 1 month. Did. Before proceeding with this experiment, 20 people were asked to use a normal shampoo (hereinafter referred to as a comparative example shampoo) and collected the dandruff accumulated for 3 days, and the weight of the collected dandruff (A) and the example soap 1 The weight (B) of dandruff accumulated for 3 days after the end of the test after allowing for use for months was compared. The dandruff reduction rate was calculated according to Equation 1 below.

[Equation 1]

Dandruff reduction rate (%) = [(Weight of dandruff before test commencement (A)(mg)-Weight of dandruff accumulated (B)(mg)) for 3 days after the end of test) / Weight of dandruff before test commencement (A)(mg)] x 100

The dandruff reduction rate (%) shown in Table 2 shows the average value of the dandruff reduction rate for 20 test subjects, and as shown in Table 2, when the example soap was used, the dandruff reduction rate was compared to the case of using the comparative example shampoo. It was confirmed that it was as high as 2.41 times.

Experimental Example 2. Measurement of change in hair thickness and density of hair

For 30 male experimenters who are undergoing hair loss, the above example soap and comparative example shampoo are used once daily in the morning and once in the evening, and after 1 month, the thickness of the hair using a phototrichogram (phototrichogram) Diameter) and the density of the hair were measured. The amount of change in hair thickness was calculated by calculating the difference between the thickness measured before using the example soap and the comparative example shampoo and the thickness measured after using the example soap and the comparative example shampoo for one month, and the hair density was 1 cm. ^The number of hairs per ² is calculated. The amount of hair thickness and the density of hair shown in Table 2 are the average values of the results for 30 subjects, and as shown in Table 2 below, when using the example soap, the hair compared to the case of using the comparative example shampoo It was confirmed that it exhibits very good efficacy in terms of thickness and hair density.

[Table 2]

Experimental Example 3. Removal of itching of scalp and measurement of hair moisturizing effect

50 males and females aged 20 to 60 living in the Busan area (randomized screening), especially those who are thought to have hair and scalp problems, can use the soap and the comparative example shampoo in each of the above examples to determine the degree of scalp itching or hair moisturization. Experimented.

Example After using the soap and the comparative example shampoo once daily in the morning and once in the evening for 1 month, evaluation was performed for each test item according to the 5-point scoring method below.

<5 point scoring method>

5: very good, 4: good, 3: normal, 2: don't know, 1: worse

The evaluation result for each item was verified by Duncan's multiple test method using SAS package. Table 3 below shows the evaluation results.

[Table 3]

As shown in Table 3, it was confirmed that the case of using the example soap had a very good evaluation in the degree of scalp itching removal and hair moisturizing ability compared to the case of using the comparative example shampoo. Accordingly, it was confirmed that the embodiment soap of the present invention has a superior effect of improving the hair and scalp troubles, such as anti-hair loss and hair growth effects, as well as antibacterial and hair moisturizing against dandruff bacteria.

Claims (12)

The first extract extracted by mixing red, red, blue, red, red, green, red, green, red, green, red, red, green, red, green, red, green, red, green, red, green, yellow, red, green, yellow, red, green, yellow, red, green, yellow, red, yellow, blue, green, yellow, red, yellow, red, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, yellow, blue, yellow, blue, yellow, blue, blue, blue, and blue.
Purslane, grafted alley, baekgangjam, dandelion, right angle, high ginseng, burdock, peppermint, sweet ginseng, county medicinal, creation, changja, rhubarb, and pine needles; And
A third extract of hot water extracted by mixing zucchini, cucumber, damsong, dandelion, eggplant, uiin, dansam, lotus, licorice, celestial, mung bean and shiitake mushrooms;
Including,
The content of the first extract compared to the total 100 parts by weight is 40 parts by weight to 80 parts by weight, the content of the second extract is 10 parts by weight to 30 parts by weight, and the content of the third extract is mixed by 10 parts by weight to 30 parts by weight The composition for preventing hair loss and promoting hair growth.
delete delete delete delete delete According to claim 1,
The first extract 100 parts by weight compared to the content of the dripping water or Yangje root is 10 parts by weight to 30 parts by weight, a composition for preventing hair loss and promoting hair growth.
According to claim 1,
The second extract 100 parts by weight compared to the purslane or grafted content is 15 parts by weight to 40 parts by weight, hair loss prevention and hair growth promoting composition.
According to claim 1,
The third extract 100 parts by weight of the pumpkin, cucumber or pineapple content is 10 parts by weight to 30 parts by weight of the composition for preventing hair loss and promoting hair growth.
The first natural product group including red sorghum, yangjaegeun, eoseongcho, snail, coffee, hannyeoncho, jujube, side lobster, golchibo, dongbok, baekbokryeong, safflower, health, geonjihwang, hyanggak, red peony, and archery Dandelion, Wootang, Gossam, Burdock, Mint, Dansam, Countess, Creation, Changja, Rhubarb and Pine needles, 2nd natural product group and pumpkin, Cucumber, Dandelion, Dandelion, Eggplant, Euiin, Dansam, Briquette, Licorice, Cnidium, Green Bean And crushing each of the third natural product groups including shiitake mushrooms;
Preparing a first extract, a second extract, and a third extract by hot-water extracting the pulverized first natural product group, second natural product group, and third natural product group, respectively; And
Mixing the prepared first extract, second extract and third extract;
It includes,
The content of the first extract compared to the total 100 parts by weight is 40 parts by weight to 80 parts by weight, the content of the second extract is 10 parts by weight to 30 parts by weight, and the content of the third extract is mixed by 10 parts by weight to 30 parts by weight That is, a method for preparing a composition for preventing hair loss and promoting hair growth.
The method of claim 10,
The hot water extraction is to be carried out at 50 ℃ to 100 ℃, a method for producing a composition for preventing hair loss and promoting hair growth.
The method of claim 10,
The hot water extraction is performed for 15 hours to 45 hours, the method for preparing a composition for preventing hair loss and promoting hair growth.

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