KR102119466B1 - 미세먼지에 의한 피부각질 형성 세포의 분화 억제를 회복할 수 있는 물질의 스크리닝 방법 및 미세먼지에 의한 피부각질 형성 세포 분화 억제의 회복용 조성물 - Google Patents

미세먼지에 의한 피부각질 형성 세포의 분화 억제를 회복할 수 있는 물질의 스크리닝 방법 및 미세먼지에 의한 피부각질 형성 세포 분화 억제의 회복용 조성물 Download PDF

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KR102119466B1
KR102119466B1 KR1020180042941A KR20180042941A KR102119466B1 KR 102119466 B1 KR102119466 B1 KR 102119466B1 KR 1020180042941 A KR1020180042941 A KR 1020180042941A KR 20180042941 A KR20180042941 A KR 20180042941A KR 102119466 B1 KR102119466 B1 KR 102119466B1
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South Korea
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keratinocytes
differentiation
composition
fine dust
skin
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KR1020180042941A
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English (en)
Korean (ko)
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KR20190119463A (ko
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최현정
김형준
이태룡
조동형
조두신
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(주)아모레퍼시픽
경희대학교 산학협력단
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Priority to KR1020180042941A priority Critical patent/KR102119466B1/ko
Priority to CN201980039628.3A priority patent/CN112334772B/zh
Priority to PCT/KR2019/004382 priority patent/WO2019199089A1/ko
Publication of KR20190119463A publication Critical patent/KR20190119463A/ko
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/318Foods, ingredients or supplements having a functional effect on health having an effect on skin health and hair or coat
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4742Keratin; Cytokeratin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
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  • Hematology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Pathology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020180042941A 2018-04-12 2018-04-12 미세먼지에 의한 피부각질 형성 세포의 분화 억제를 회복할 수 있는 물질의 스크리닝 방법 및 미세먼지에 의한 피부각질 형성 세포 분화 억제의 회복용 조성물 KR102119466B1 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020180042941A KR102119466B1 (ko) 2018-04-12 2018-04-12 미세먼지에 의한 피부각질 형성 세포의 분화 억제를 회복할 수 있는 물질의 스크리닝 방법 및 미세먼지에 의한 피부각질 형성 세포 분화 억제의 회복용 조성물
CN201980039628.3A CN112334772B (zh) 2018-04-12 2019-04-11 能够恢复由微尘引起的皮肤角质形成细胞分化抑制的物质的筛选方法及组合物
PCT/KR2019/004382 WO2019199089A1 (ko) 2018-04-12 2019-04-11 미세먼지에 의한 피부각질 형성 세포의 분화 억제를 회복할 수 있는 물질의 스크리닝 방법 및 미세먼지에 의한 피부각질 형성 세포 분화 억제의 회복용 조성물

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Application Number Priority Date Filing Date Title
KR1020180042941A KR102119466B1 (ko) 2018-04-12 2018-04-12 미세먼지에 의한 피부각질 형성 세포의 분화 억제를 회복할 수 있는 물질의 스크리닝 방법 및 미세먼지에 의한 피부각질 형성 세포 분화 억제의 회복용 조성물

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KR20190119463A KR20190119463A (ko) 2019-10-22
KR102119466B1 true KR102119466B1 (ko) 2020-06-08

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JP7295683B2 (ja) * 2019-03-29 2023-06-21 株式会社マンダム 皮膚疾患の指標の検出方法、物質の評価方法、並びに、ロリクリン量及び/又はフィラグリン量の増加剤

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CN106491509A (zh) * 2007-04-27 2017-03-15 欧莱雅 美容皮肤处理方法和皮肤护理美容产品
US20110008273A1 (en) * 2008-03-11 2011-01-13 Shiseido Company, Ltd. Methods of skin whitening and of screening skin-spot-formation inhibiting and/or skin-spot removing factor
KR101785347B1 (ko) * 2010-11-19 2017-10-17 (주)아모레퍼시픽 피부 세포 분화 촉진 물질의 스크리닝 방법
KR102635189B1 (ko) * 2015-04-06 2024-02-13 (주)아모레퍼시픽 미세먼지에 의한 피부 손상 진단용 조성물 및 갈랑긴을 유효성분으로 포함하는 조성물
KR102394639B1 (ko) * 2015-11-19 2022-05-09 (주)아모레퍼시픽 각질세포 분화 촉진 물질의 스크리닝 방법
KR102600091B1 (ko) * 2016-08-24 2023-11-09 (주)아모레퍼시픽 사이토칼라신 d를 포함하는 피부 미백용 조성물
KR102541259B1 (ko) * 2016-08-25 2023-06-12 (주)아모레퍼시픽 일차 섬모를 조절하는 피부 미백 물질 스크리닝 방법
KR102610932B1 (ko) * 2016-09-23 2023-12-08 (주)아모레퍼시픽 Card18 발현 촉진 물질을 포함하는 피부 장벽기능 강화용 조성물 및 card18 촉진 물질의 스크리닝 방법

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Ezratty et al., Cell, Vol. 145, 2011, pp. 1129-1141.*
H. J. Kim et al., Toxicology Letters, Vol. 273, 2017, pp. 26-35.*

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CN112334772A (zh) 2021-02-05
CN112334772B (zh) 2023-12-15
KR20190119463A (ko) 2019-10-22
WO2019199089A1 (ko) 2019-10-17

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