KR102073687B1 - A method and apparatus for providing customized cosmetics - Google Patents

Abstract

The present invention relates to a customized cosmetic recommendation system and method using a genetic test, in particular to analyze the skin condition of the individual through an objective and scientific skin genetic test and to improve the skin condition based on the results, more specifically, Personalized cosmetics using genetic tests with functional ingredients that can improve skin condition more effectively by precisely qualitatively quantifying and quantifying the expression level of specific genes related to skin moisturizing, elasticity, wrinkles, and whitening of each user. Regarding the recommendation system and method,
Acquiring user data by an input method; The user's propensity pattern is analyzed by calculating the input data and genetic information, and when grouping similar groups, the skin is classified into a high risk group, a low risk group, and a good group with a 100-point conversion standard score of each skin index. Steps; Grouping similar groups of skin types by weighting indicators of pigmentation, aging, and elasticity of gene information; Classifying the similar groups by skin type in each similar group; Genetic information is converted into 100 points based on the results of the professional genetic analysis institutes and classified into good / caution / management by score range to identify the current skin care status and suggest directions based on the innate genes. to be.

Description

A method and apparatus for providing customized cosmetics using big data and personal skin information

The present invention relates to a personalized cosmetic recommendation system and method using big data and personal skin information, and in particular, to analyze skin conditions of individuals through objective and scientific skin genetic tests and to improve skin conditions based on the results. , More specifically, by precisely qualitatively quantifying and quantifying the expression level of specific genes related to skin moisturization, elasticity, wrinkles and whitening, and then adding functional ingredients to improve skin condition more effectively based on the results. The present invention relates to a customized cosmetic recommendation system and method using big data and personal skin information.

In general, a person's skin has a different skin condition for each individual. In particular, even at the same age and the same skin type, the skin condition can vary depending on the internal and external environment of the individual. As scientific civilization develops, there are more cases of serious condition affecting the skin due to exposure of various polluted environment, ultraviolet exposure due to destruction of ozone layer, various stresses, deterioration of skin function and even skin trouble. . Therefore, users are increasingly interested in functional cosmetics that can improve or maintain skin condition.

However, at present, the recognition of the skin condition mainly for each user is enough to grasp how the skin condition of one's own skin is through simple skin examination and simple skin test, so it is difficult to obtain full confidence in the skin condition information. In addition, functional cosmetics that are currently on the market are not targeted at individuals, but because of their general purpose, there are many limitations in finding a suitable cosmetic product for the user.

In the conventional method of measuring the skin condition and providing customized cosmetics, in order to check the current skin condition of the user, the wrinkles are mainly detected using an image analyzer system to determine the state of the skin wrinkles, and the skin In the case of whitening, the change of erythema or skin color is measured by using a mexameter and a colorimeter.In the case of skin moisturizing, the amount of moisturizing is mainly measured by using a corneometer. In the case of skin elasticity, a cutometer is used to measure skin elasticity.

These measurement methods represent the physical state of the skin surface as a simple numerical value, and there is a possibility that an error may occur in evaluating the small degree of improvement of the examinee because the numerical value may vary depending on the measuring program. In addition, in the case of the visual evaluation of the examiner and the questionnaire evaluation of the examinee, the subjective side greatly affects the difficulty of objectively and precisely evaluating the skin condition of the examinee. Therefore, there are many limitations in providing customized cosmetics to the user through this measuring method.

In addition, since the state is measured and measured on the entire skin of the user's face, only a uniform prescription for the entire area of the user's face is possible, and detailed management cannot be achieved.

Korean Laid-Open Patent Publication No. 2007-0100158 (October 10, 2007) Korea Patent Publication No. 10-1555636 (2015. 09. 18)

The present invention is to solve the above problems, to obtain the data of the user as an input method; The user's propensity pattern is analyzed by calculating the input data and genetic information.When grouping similar groups, the skin scores are divided into high risk group, low risk group and good group with 100 points of reference scores. ; Gene information is also weighted to indicators of pigmentation, aging and elasticity to bind similar groups of skin types; Each similar group is classified into similar groups by skin type; Genetic information is converted into 100 points out of 100 points based on the results of gene analysis specialists, and classified as good / caution / management by score range so that current skin care status can be confirmed and suggested based on innate genes. There is this.

As a means for achieving the above object,

The present invention includes the steps of acquiring the user's data through the questionnaire data receiving unit; Genetic information is received through the genetic information receiving unit, and the user's propensity pattern is analyzed by calculating the input questionnaire data and the genetic information.In this case, when grouping similar groups, each skin indicator has a 100-point conversion baseline score and a high risk level. Dividing the group into a low risk group and a good group; Grouping similar groups of skin types by weighting indicators of pigmentation, aging, and elasticity of gene information; Classifying the similar groups by skin type in each similar group; Genetic information is converted into 100 points out of 100 points based on the results of gene analysis specialists, and classified into good / caution / management by score range, to check the current state of skin care based on natural genes, and to apply cosmetics as a means of selecting appropriate cosmetics. It is characterized by the step of selecting.

In addition, the selected functional cosmetic information is characterized in that it comprises a cosmetic component and content.

In addition, the skin function gene is characterized in that it is related to one or more skin functions of moisturizing, elasticity, wrinkles and whitening.

In addition, the gene information receiving unit 110 for receiving and outputting the genetic information of the subject; A questionnaire data receiver 120 for receiving and outputting response data of the subject to the questionnaire items; A gene DB 130 for storing expression information of skin function genes; A cosmetic DB 160 for storing information on skin functional cosmetics; A skin function gene grading unit 140 for comparing the gene information received by the gene information receiving unit 110 with the gene DB 130 to determine a skin function gene grade of the subject; A suitable cosmetic selection determining unit 150 for selecting and selecting based on the cosmetic DB 160 to improve the skin corresponding to the skin function gene grade determined by the skin function gene grading unit 140; Measuring and transmitting whether the fine dust in the open air to the suitable cosmetic selection determining unit is greater than the reference, and the dust measuring means (1000) for inducing to include chitosan, alginic acid, beta glucan, gamma-PGA in the suitable cosmetic selection determining unit It is characterized by including the configuration.

In addition, the dust measuring means 1000, the infrared transmitting means (A) for emitting infrared rays, and is located opposite to the infrared transmitting means and receives the light emitted from the infrared transmitting means to the extent of the received amount According to the infrared receiver (B) for determining the dust inflow, and the dust measurement for controlling the input voltage of the infrared transmitting means (A) to increase if the output voltage of the infrared receiving means (B) is less than the set value A control unit C; The infrared transmitting means (A) comprises: a concave lens group mounted with a plurality of concave lenses to limit the output of the infrared; An infrared ray transmitting element proximate to the concave lens group and outputting infrared rays; It is installed on one side of the concave lens group to flow the concave lens group to adjust the infrared output, but if the ambient temperature is high according to the change in temperature, the concave lens group flows to the left to pass infrared light through the lens with a low depression angle A shape memory spring that controls the output to be high and controls the infrared output to be lowered by passing the concave lens group to the right when the ambient temperature is low and allowing infrared light to pass through the lens having a high depression angle; Located at the right end of the shape memory spring is characterized in that it comprises a fixing portion for supporting the movement of the shape memory spring.

In addition, the infrared transmitting means (A), the housing for receiving the shape memory spring and the fixing portion; It is installed inside the housing, but installed on one side of the shape memory spring forcibly expands the shape memory spring through heat to move the concave lens group to the left, thereby allowing infrared light to pass through the lens with a low depression angle to output infrared light Heating means for inducing this force to be raised; It is installed on the inside of the housing, but installed on the other side of the shape memory spring to transfer the cooling heat to force the shape memory spring to contract to move the concave lens group to the right, thereby allowing the lens with high depression angle and infrared light to pass through A thermoelectric element for inducing an infrared output to be forcibly lowered; It is electrically connected to the heat generating means and the thermoelectric element, and if there is a lot of dust to control the operation to increase the infrared output, and if there is little dust including a transmission control unit for controlling to lower the infrared output by operating the thermoelectric element; It is characterized by configuration.

As described above, the present invention acquires data of a user through an input method; The user's propensity pattern is analyzed by calculating the input data and genetic information.When grouping similar groups, the skin scores are divided into high risk group, low risk group and good group with 100 points of reference scores. ; Gene information is also weighted to indicators of pigmentation, aging and elasticity to bind similar groups of skin types; Each similar group is classified into similar groups by skin type; Genetic information is converted into 100 points out of 100 points based on the results of a professional genetic analysis agency, classified as good / careful / management by score range, it has the effect of confirming the current state of skin care and suggest the direction based on the innate gene.

1 is an overall conceptual diagram of the present invention.
2 is a conceptual diagram of skin type determination of the present invention.
Figure 3 is a conceptual diagram of skin type determination of the present invention.
Figure 4 is a conceptual diagram of the skin type score of the present invention.
5 is a conceptual view of cosmetics recommendation of the present invention.
6 is a data flow diagram of the present invention.
7 is a conceptual diagram of mobile application of the present invention.
8 is a skin type survey and determination conceptual diagram of the present invention.
9 is a system configuration diagram of the present invention.
10 is a conceptual diagram of an infrared ray transmitting means and an infrared ray receiving means constituting the dust measuring means of the present invention.
11 is a conceptual diagram for measuring the dust using the infrared transmitting means and infrared receiving means of the present invention.
Figure 12 is a first embodiment of the dust measuring means having a shape memory spring in the present invention.
Figure 13 is a second embodiment having a heat generating means, a thermoelectric element and a shape memory spring in the present invention.
14 is a concave lens configuration applied to the present invention.

Hereinafter, with reference to the accompanying drawings and description will be described in detail the operating principle of the preferred embodiment of the present invention. However, the drawings and the following description shown below are for the preferred method among various methods for effectively explaining the features of the present invention, the present invention is not limited only to the drawings and description below.

In addition, in the following description of the present invention, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. Terms to be described later are terms defined in consideration of functions in the present invention, which may vary according to intentions or customs of users or operators. Therefore, the definition should be made based on the contents throughout the present invention.

In addition, preferred embodiments of the present invention to be carried out below are already provided in each system functional configuration to efficiently describe the technical components constituting the present invention, or system functions that are commonly provided in the art to which the present invention belongs The configuration is omitted as much as possible, and will be described mainly on the functional configuration to be additionally provided for the present invention.

If those skilled in the art to which the present invention pertains, it will be easy to understand the function of the components already used in the prior art among the omitted functional configuration not shown below, and also the configuration omitted as described above The relationship between the elements and the components added for the present invention will also be clearly understood.

In addition, the following examples will be used to appropriately modify the terminology so that those skilled in the art to clearly understand the technical features of the present invention to effectively understand, but the present invention is It is by no means limited.

As a result, the technical spirit of the present invention is determined by the claims, and the following embodiments are one means for efficiently explaining the technical spirit of the present invention to those skilled in the art to which the present invention pertains. It's just

1 is an overall conceptual diagram of the present invention.

2 is a conceptual diagram of skin type determination of the present invention.

Figure 3 is a conceptual diagram of skin type determination of the present invention.

Figure 4 is a conceptual diagram of the skin type score of the present invention.

5 is a conceptual view of cosmetics recommendation of the present invention.

6 is a data flow diagram of the present invention.

7 is a conceptual diagram of mobile application of the present invention.

8 is a skin type survey and determination conceptual diagram of the present invention.

9 is a system configuration diagram of the present invention.

10 is a conceptual diagram of an infrared ray transmitting means and an infrared ray receiving means constituting the dust measuring means of the present invention.

11 is a conceptual diagram for measuring the dust using the infrared transmitting means and infrared receiving means of the present invention.

Figure 12 is a first embodiment of the dust measuring means having a shape memory spring in the present invention.

Figure 13 is a second embodiment having a heat generating means, a thermoelectric element and a shape memory spring in the present invention.

14 is a concave lens configuration diagram applied to the present invention,

The present invention comprises the steps of acquiring data of a user through an input method;

Analyze the user's propensity pattern by calculating the input data and genetic information.When grouping similar groups, 100-point conversion standard score of each skin indicator is divided into high risk group, low risk group and good group. Steps;

Grouping similar groups of skin types by weighting indicators of pigmentation, aging, and elasticity of gene information;

Classifying the similar groups by skin type in each similar group;

Genetic information is converted into 100 points based on the results of the professional genetic analysis institutes are classified into good / careful / management by score range, and consists of the steps to check the current state of skin care and suggest directions based on the innate gene.

Looking at how to receive user data above, beauty data such as reviews on cosmetics-oriented beauty products and brands on social networks and the web, thoughts on design and brand, evaluation, place of purchase, feeling of use Collect and analyze beauty trends on big data platform. In addition, through the self-diagnosis of the skin grouping users based on similar analysis results, we recommend cosmetics that are optimized for personal molding through collaborative filtering based on weight of individual skin type and genetic information.

In addition, group information and final recommendation information collected from social networks and the web are accumulated and combined with existing analysis information to recommend more accurate cosmetics to additional users.

Skin type determination using genetic testing is performed by a genetic testing unit for the skin of each region of the multi-region to determine whether the skin type of each region of the multi-region is moisturizing, wrinkled, sensitive or whitening Done. To this end, the genetic test unit may include one or more single nucleotide polymorphism markers selected from single nucleotide polymorphism (SNP) markers to determine whether the skin type is moisturizing, and one selected from single nucleotide polymorphism markers to determine whether the skin type is wrinkles. One or more single nucleotide polymorphism markers, one or more single nucleotide polymorphism markers selected from among single nucleotide polymorphism markers to determine whether the skin type is sensitive, and one or more selected from single nucleotide polymorphism markers to determine whether the skin type is whitening Diagnostic kits using monobasic polymorphic markers and having a diagnostic composition comprising a probe capable of detecting these skin type diagnostic markers or an amplifying agent can be used. The diagnostic kit may be provided as an RT-PCR kit or a DNA chip kit.

The method of collecting the skin cells of the examinee is not particularly limited, but, preferably, the tape stripping method is performed by attaching a cellophane tape to a part of the examinee's forehead, eyes, cheeks, chin, and the like, and detaching the cellophane tape. Skin cells can be harvested. In addition, the process of extracting the gene from the skin cells includes the step of extracting the total RNA or DNA of the skin cells from the collected skin cells. (See Rita Wong, Vynga Tran, Vera Morhenn, She-pin Hung, Bogi Andersen, Elaine Ito, G. Wesley Hatfield, and Nicholas R. Benson.Use of RT-PCR and DNA Microarrys to Characterize RNA Recovered by Non-Invasive Tape Harvestion of Normal and Inflamed Skin., J Invest Dermatol 123: 159-167, 2004.)

On the other hand, if such a marker and diagnostic kit is prepared, (a) obtaining DNA from the skin cells collected from the skin of each region of the subject's face, (b) the single above-mentioned from the DNA obtained in step (a) Amplifying the polymorphic site of the nucleotide polymorphism marker or hybridizing with the probe, and (c) identifying the base of the amplified or hybridized polymorphic site of step (b), each region of the divided multi-region of the subject. You will be able to understand the skin type of each star.

However, the method of collecting the skin cells of the examinee is not particularly limited, but preferably, the skin cells may be collected by attaching a cellophane tape to the skin of the corresponding area and then peeling it off. .

In addition, the process of extracting the gene from the skin cells includes the step of extracting the DNA of the skin cells from the collected skin cells. (See Rita Wong, Vynga Tran, Vera Morhenn, She-pin Hung, Bogi Andersen, Elaine Ito, G. Wesley Hatfield, and Nicholas R. Benson.Use of RT-PCR and DNA Microarrys to Characterize RNA Recovered by Non-Invasive Tape Harvestion of Normal and Inflamed Skin., J Invest Dermatol 123: 159-167, 2004.)

As such, in the case of techniques for determining whether the skin type is moisturizing, wrinkled, sensitive, or whitening by using a genetic test, Korean Patent Application Publication No. 2013-0016009 (2013.02) See .14 for more details.

Looking at Korean Patent Laid-Open Publication No. 2013-0016009 includes the following information on the single nucleotide polymorphism markers that can determine whether the skin type is moisturizing, wrinkled, sensitive or whitening. In other words, the single nucleotide polymorphism (SNP) markers for determining whether the skin type is moisturizing include 5-100 consecutive sequences including the 129412726th base, wherein the 129412726th base of the human chromosome 12 is C or T (rs28459381). Polynucleotide consisting of a DNA sequence; A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 29663843 th base, wherein the 29663843 th base of human chromosome 6 is C or T (rs1233387); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising said 29820388 base, wherein the 29820388th base of human chromosome 7 is C or T (rs174922); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29820850 base, wherein the 29820850th base of human chromosome 7 is T or C (rs174923); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 141425903 base, wherein the 141425903 base of the chromosome 7 of human is C or T (rs12666982); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 29105682 base, wherein the 29105682 base of human chromosome 3 is G or A (rs9818278); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising said 125175173 base, wherein the 125175173rd base of human chromosome 5 is T or C (rs12109492); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 59132422 base, wherein the 59132422 base of human chromosome 12 is C or T (rs12228176); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 52868639 th base, wherein the 52868639 th base of human chromosome 2 is C or T (rs7581434); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 52856195 th base, wherein the 52856195 th base of human chromosome 2 is G or T (rs7573204); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 59106853th base, wherein the 59106853th base of human chromosome 12 is T or C (rs3923917); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 4600440th base, wherein the 4600440th base of human chromosome 20 is A or G (rs28702443); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29914639 th base, wherein the 29914639 th base of the human 10th chromosome is G or A (rs4572039); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 95705228 base, wherein the 95705228 base of the eighth chromosome of human is C or T (rs2890805); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 25590529 base, wherein the 25590529 base of the 15th chromosome of human is A or G (rs25590529); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 107093501 base, wherein the 107093501 base of the human 6th chromosome is G or A (rs783400); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 25586993 base, wherein the 25586993 base of the human 15th chromosome is C or T (rs3098582); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 25585078 base, wherein the 25585078 base of the human 15th chromosome is T or C (rs12591822); And one or more polynucleotides selected from the group consisting of complementary polynucleotides thereof.

In addition, the single nucleotide polymorphism markers for determining whether the skin type is wrinkles include 5-100 consecutive DNAs containing the 24551208 base, wherein the 24551208th base of human chromosome 7 is A or G (rs2711118). Polynucleotides consisting of sequences; A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 76839279 base, wherein the 76839279 base of the chromosome 5 is A or G (rs4273585); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 208672298 base, wherein the 208672298 base of the chromosome 1 of human is C or T (rs11119496); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 52738724 base, wherein the 52738724 base of the chromosome 20 of human is T or C (rs6127255); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising said 27346024 base, wherein the 27346024 base of human chromosome 7 is C or T (rs2158769); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 47954398 base, wherein the 47954398 base of the chromosome 15 of human is A or C (rs16963008); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 101951190th base, wherein the 101951190th base of human chromosome 3 is T or C (rs1048364); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 101936968 base, wherein the 101936968 base of human chromosome 3 is G or A (rs931206); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 106740691th base, wherein the 106740691th base of human chromosome 13 is T or C (rs9555341); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 122472521 base, wherein the 122472521 base of the chromosome 10 is C or T (rs10886747); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 177330499th base, wherein the 177330499th base of human chromosome 4 is G or T (rs4538426); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 177322010 base, wherein the 177322010 base of the human chromosome 4 is C or T (rs2170576); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 51222720 base, wherein the 51222720 base of human chromosome 12 is G or A (rs11170170); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 107123424 base, wherein the 107123424 base of the human chromosome 6 is T or C (rs3747790); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 68751073th base, wherein the 68751073th base of human chromosome 11 is T or G (rs7931342); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 199554152 base, wherein the 199554152 base of human chromosome 1 is C or T (rs916398); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 72820331th base, wherein the 72820331th base of human chromosome 10 is G or A (rs10999801); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 72805925th base, wherein the 72805925th base of human chromosome 10 is A or G (rs1417210); And one or more polynucleotides selected from the group consisting of complementary polynucleotides thereof.

In addition, the monobasic polymorphic markers that determine whether the skin type is sensitive include 5-100 consecutive DNA sequences comprising the 153923073 base, wherein the 153923073 base of the human chromosome 6 is C or T (rs576496). Polynucleotide consisting of; A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 111003744th base, wherein the 111003744th base of human chromosome 9 is C or T (rs7021903); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 108135402 th base, wherein the 108135402 th base of human chromosome 6 is T or C (rs6921267); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 113245651th base, wherein the 113245651th base of human chromosome 3 is G or A (rs7650263); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134456647 base, wherein the 134456647 base of the human chromosome 2 is G or A (rs16829881); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134467821st base, wherein the 134467821st base of human chromosome 2 is A or G (rs2321546); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 63359260 base, wherein the 63359260th base of human chromosome 18 is G or C (rs9957826); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 4268219 base, wherein the 4268219 base of the human chromosome 2 is G or A (rs17018897); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising said 46170608 base, wherein the 46170608th base of human chromosome 2 is A or T (rs1868273); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 153943264 base, wherein the 153943264 base of the chromosome 6 is C or T (rs6920377); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 46175944 base, wherein the 46175944 base of human chromosome 2 is G or C (rs4953307); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 75476916 base, wherein the 75476916 base of the human chromosome 4 is C or T (rs6446995); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 79763138 th base wherein the 79763138 th base of human chromosome 9 is C or T (rs11145633); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 20125657 base, wherein the 20125657th base of human chromosome 13 is G or A (rs9506530); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 111001210th base, wherein the 111001210th base of human chromosome 9 is C or T (rs7875754); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 36732263 base, wherein the 36732263 base of the human chromosome 2 is G or T (rs11883493); And one or more polynucleotides selected from the group consisting of complementary polynucleotides thereof.

In addition, the single nucleotide polymorphism markers for determining whether the skin type is whitening include 5-100 consecutive DNAs containing the 54189156 base, wherein the 54189156 base of the human chromosome 10 is T or C (rs1100311). Polynucleotides consisting of sequences; A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 82834514 base, wherein the 82834514th base of human chromosome 5 is G or A (rs1833890); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 55831811 base, wherein the 55831811 base of the chromosome 1 of human is T or C (rs7526426); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 191042669 base, wherein the 191042669 base of human chromosome 2 is G or A (rs1019321); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising said 54169046 base, wherein said 54169046 base of human chromosome 10 is C or T (rs1238575); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 82829792 base, wherein the 82829792 base of the human chromosome 5 is G or T (rs2652106); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 43428336 base, wherein the 43428336 base of human chromosome 13 is G or A (rs7322264); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54196212 base, wherein the 54196212th base of human chromosome 10 is T or C (rs1082479); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 191009613 th base, wherein the 191009613 th base of human chromosome 2 is A or G (rs9646748); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 55855971 base, wherein the 55855971 base of human chromosome 1 is T or C (rs1118219); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134657139 base, wherein the 134657139th base of human chromosome 3 is C or T (rs9865003); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54182014 base, wherein the 54182014 base of human chromosome 10 is T or G (rs1100311); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54191096th base, wherein the 54191096th base of human chromosome 10 is C or T (rs1693307); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 4860027th base, wherein the 4860027th base of human chromosome 6 is A or G (rs9405785); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 79431934 base, wherein the 79431934 base of the human chromosome 4 is G or T (rs1484344); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 32866528th base, wherein the 32866528th base of human chromosome 14 is G or A (rs8011225); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 83969386th base, wherein the 83969386th base of human chromosome 1 is A (rs3470503); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 22067299 base, wherein the 22067299 base of human chromosome 16 is T or G (rs1164222); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134656869 th base, wherein the 134656869 th base of human chromosome 3 is C or T (rs2370246); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 191098371 base, wherein the 191098371 th base of human chromosome 2 is A or G (rs1093145); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 188206372 base, wherein the 188206372 base of human chromosome 1 is G or A (rs1711758); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 191041973 base, wherein the 191041973 base of human chromosome 2 is T or C (rs4340549); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 96368401 base, wherein the 96368401 th base of human chromosome 15 is T or C (rs2845633); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54203366 base, wherein the 54203366th base of human chromosome 10 is A or G (rs1031101); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29970271 th base, wherein the 29970271 th base of human chromosome 8 is G or A (rs6987138); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 900218th base, wherein the 900218th base of human chromosome 20 is C or T (rs2223962); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 37655240th base, wherein the 37655240th base of human chromosome 6 is G or A (rs804846); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 235675961 th base, wherein the 235675961 th base of human chromosome 2 is A or G (rs4277473); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 43418348 base, wherein the 43418348 base of human chromosome 13 is T or C (rs9525880); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 58468246 base, wherein the 58468246 base of the chromosome 5 of human is C or T (rs1006239); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54173326 base, wherein the 54173326th base of human chromosome 10 is G or A (rs996232); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 244670509th base, wherein the 244670509th base of human chromosome 1 is C or T (rs2340778); A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 158512290 base, wherein the 158512290th base of human chromosome 5 is A or G (rs6556401); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 17963006 base, wherein the 17963006 base of the chromosome 8 of human is A or G (rs1763609); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 67559320 base, wherein the 67559320 base of human chromosome 17 is T or C (rs9911193); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 65093758 base, wherein the 65093758 base of human chromosome 16 is T or C (rs1428106); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 20186505 base, wherein the 20186505 base of human chromosome 9 is T or G (rs1456958); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 20186466 base, wherein the 20186466th base of human chromosome 9 is T or C (rs1456959); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 20218652 base, wherein the 20218652 base of the chromosome 9 of human is C or T (rs321218); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising said 19969813 base, wherein the 19969813th base of human chromosome 9 is A or C (rs1892011); And one or more polynucleotides selected from the group consisting of complementary polynucleotides thereof.

Meanwhile, another method of determining whether the skin type is moisturizing, wrinkled, sensitive, or whitening through genetic testing has been disclosed in Korean Patent Publication No. 2007-0100158 (2007.10.10). In particular, Korean Patent Publication No. 2007-0100158 includes genes related to moisturizing and elasticity such as AQP3, HAS3, PIGA, FLG, DSP, DSC1, PPL, DSG1, LOR, CESN, IVS, TGM1, KRT14, KRT5, KRT6A, KRT1, KRT2A, KRT15, COL17A1, KLK7, C-myc, MC5R, CAP1 / Press8 and the genes related to wrinkles are MMP1, MMP8, MMP13, NFκB, MMP10, MMP3, MMP2, MMP9, and the genes related to whitening are TYR, TRP1, It reveals that it is TRP2, MITF, MLANA, SILV, PAX3, SOX10, TFAP2A, and includes contents carried out according to a conventional real-time PCR method known as the most reliable Taqman method.

In addition, to determine the expression level of the gene to determine the skin type can be performed using a DNA chip. The DNA chip is a device capable of simultaneously analyzing a large number of genes with only a very small amount of sample and analyzing genetic expression information very quickly. The DNA chip is made of hundreds to hundreds of thousands of DNA in a very small space, the production method of this DNA chip and a measuring method using the same are known in the art, the gene using the DNA chip according to this known method The expression level of can be measured.

Thereafter, the cosmetic manufacturing step (S107) is carried out. In the cosmetic manufacturing step (S107) by selecting the cosmetic functional cosmetics that need to be supplemented to improve the skin of each of the multiple areas based on the skin type determined in the previous step by adding to the basic ingredients each Customized cosmetics are produced by area. Here, the cosmetic manufacturing method according to the skin type is disclosed in detail in Korean Patent Publication No. 2007-0100158 (2007.10.10) can be referred to.

Here, the moisturizing improvement component, sodium hyaluronate 0.1-30% by weight, phytosterols 0.1-20% by weight, soybean ferment extract 0.1-30% by weight, amino acids 0.01-10 wt%, Collagen 0.1-30 wt%, Polysaccharides 0.5-20 wt%, Sphingolipids 0.01-5.0 wt%, α-hydroxy acid ) From 0.5 to 20% by weight, from 0.5 to 20% by weight of β-hydroxyacid, from 1 to 10% by weight of urea, and from 0.1 to 30% by weight of β-glucan. One or more kinds selected may be used.

Wrinkle improvement ingredients include Adenosine 0.04-1.0 wt%, Retinol 1 x 102-5 X 103 IU / g, Retinyl palmitate 1X103-1X106 IU / g, Vitamin C and its derivatives (Vitamin C and derivatives) 0.1-20 wt%, Vitamin E and derivatives 0.1-100 wt%, Peptides 0.01-20 wt%, Coenzyme Q 10 (Coenzyme Q10) 0.005 ~ 0.2 % By weight, 1.0-20% by weight of perfluoropolyether, 1 ppm or less of epidermal growth factor, 0.1-10% by weight of Ginseng extract, and 0.1-20% of Green tea extract One or more types selected from the group consisting of% by weight can be used.

The elasticity-improving component added according to the expression of genes related to elasticity is 0.1-20% by weight of vitamin C and its derivatives (Vitamin C and derivatives), 0.1-20% by weight of tomato extract (Lycopene), isoflavons 0.5-20 wt%, Pomegranate extract 0.5-20 wt%, Polyphenols 0.1-10 wt%, Wild yam extract 0.1-20 wt%, Sphingolipids 0.01 ~ One or more selected from the group consisting of 5.0% by weight and 0.01 to 20% by weight of peptides can be used.

The whitening improvement ingredients include vitamin C and derivatives of 0.1-20% by weight, arbutin 0.5-7% by weight, berry extract 0.1-20% by weight, oil-soluble licorice extract ) 0.01-5% by weight, Wild mountain ginseng adventitious roots extract 1.0-20%, Ephedra sinica extract 0.1-10% by weight, Rooibos extract 0.1-20% by weight One or more types selected from the group can be used.

9 is a configuration example of a customized cosmetics information providing system according to the present invention, according to the gene information receiving unit 110 for receiving and outputting the genetic information of the subject; Questionnaire data receiving unit 120 for receiving and outputting the response data of the subject to the questionnaire item; Gene DB 130 for storing the expression information of the skin function gene; Cosmetic DB 160 for storing information of the skin functional cosmetics; A skin function gene grading unit 140 for comparing the gene information received by the gene information receiving unit 110 with the gene DB 130 to determine a skin function gene grade of the subject; In order to improve the skin corresponding to the skin function gene grade determined in 140, a suitable cosmetic selection determination unit 150 to determine the selection based on the cosmetic DB (160); includes.

On the other hand, the present invention is further provided with a dust measuring means 1000 for measuring the outdoor fine dust and electrically connected to the appropriate cosmetic selection determining unit, it is determined that there is dust above the measurement result of the dust measuring means 1000 When the appropriate cosmetics selection decision unit is notified, the fine dust is higher than the standard.At the same time, the suitable cosmetics selection decision unit will convert chitosan, alginic acid, beta glucan, and gamma-PGA that have adsorption or removal performance of ultra-fine dust to the appropriate cosmetics. Induce further inclusion.

The dust measuring means 1000 of the present invention is positioned to face the infrared transmitting means (A) for emitting infrared rays and the infrared transmitting means, and receives the light emitted from the infrared transmitting means and according to the degree of the received amount An infrared receiver (B) for determining dust inflow and a dust measurement controller for controlling the input voltage of the infrared transmitter (A) to increase when the output voltage of the infrared receiver (B) is smaller than a set value (C) is made.

In addition, the infrared ray transmitting means (A) receives an infrared ray transmission control signal from the dust measurement control unit (C) to determine the amount of infrared ray transmission and outputs the changed infrared ray transmission amount.

That is, when the resultant value of the infrared receiver B is transmitted to the dust measurement controller C, the dust measurement controller C predicts the dust generation amount based on the data of the infrared receiver B, and according to the dust generation amount. By outputting a control signal to the infrared transmitting means (A) to adjust the amount of infrared transmission to guide the output.

That is, the dust measurement control unit reads the light quantity data output from the infrared receiving means, and automatically controls the light quantity of the infrared light emitting means based on this, so that the sensitivity control is automatically maintained constant so that dust detection is optimal even in the contamination situation caused by dust. It is to keep the sensitivity and measure.

In other words, the dust measurement control unit C determines that the pollution degree is high when the amount of received light of the infrared receiver B is weak, and outputs a control signal to increase the amount of light of the infrared transmitter A for more accurate dust measurement. If the received light amount of the infrared ray receiving means C is too high, it is a state without contamination or it is difficult to precisely measure the output signal so as to lower the amount of light of the infrared ray transmitting means A. That is, it is necessary to keep the amount of infrared rays transmitting light in an appropriate state. Only then, the amount of infrared radiation measured by the infrared receiver can be accurate, so that dust generation can be predicted more precisely. Therefore, the dust amount data measured by the dust measurement control unit of the present invention can output a dust measurement result of high reliability.

The present invention includes a concave lens group (1) mounted with a plurality of concave lenses to limit the output of the infrared;

An infrared transmitting element (2) which is close to the concave lens group and outputs infrared rays;

It is installed on one side of the concave lens group to flow the concave lens group to adjust the infrared output, but if the ambient temperature is high according to the change in temperature, the concave lens group flows to the left to pass infrared light through the lens with a low depression angle A shape memory spring 3 which controls the output to be high and controls the infrared output to be lowered by passing the concave lens group to the right when the ambient temperature is low and allowing infrared light to pass through the lens having a high depression angle;

Located at the right end of the shape memory spring is configured to include a fixing portion (4) for supporting the movement of the shape memory spring.

And, the housing (5) for receiving the spring and the fixing portion;

It is installed inside the housing, but installed on one side of the shape memory spring forcibly expands the shape memory spring through the heating to move the concave lens group to the left, thereby allowing infrared light to pass through the lens with a low depression angle to output infrared Heat generating means (6) for inducing this force to be raised;

It is installed on the inside of the housing but installed on the other side of the shape memory spring (3) to transfer the cooling heat to force the shape memory spring (3) to shrink to move the concave lens group to the right, accordingly the lens with a high depression angle And a thermoelectric element 7 for inducing infrared rays to pass through to induce the infrared output to be forcibly lowered.

The transmission control unit 8 is electrically connected to the heat generating means and the thermoelectric element, and controls to increase the infrared output by operating the heating means when there is a lot of dust, and to reduce the infrared output by operating the thermoelectric element when there is little dust. Consists of including.

In addition, a plurality of holes 5a and 5b 5c are formed at the edge of the housing in which the fixing part 4 is positioned, and the magnet 9 is inserted into and coupled to the hole to set the position of the fixing part 4. Is done.

That is, the fixing part 4 is made of metal, and the magnet 9 is inserted into the hole to temporarily fix the fixing part. Accordingly, the area with low temperature is set by placing the magnet in the center hole 5b or the left hole 5a, and the area with high temperature is set by placing the magnet 9 in the center hole 5b or the right 5c. do.

Then, the position of the first transmission element 2 is located at the center of the concave lens group 1, and then expands and contracts properly according to the temperature change so that the concentration of dust can be accurately determined.

The present invention is configured to automatically adjust the output of the transmission element 2 according to the change in temperature, the shape memory spring (3) is set to the default temperature, and after the temperature rises, the shape memory spring increases and the The light is reduced and output, and when the temperature decreases, the shape memory spring 3 is reduced and the light of the transmitting element 2 is lowered and output.

That is, since the dust is distributed in the gas, the movement becomes active when the temperature rises, so that it is possible to check the dust concentration more precisely than when the output of the transmitting element 2 is lowered, and when the temperature decreases, the movement becomes dull. You can check the dust concentration more precisely than when you increased the output of 2).

Accordingly, the present invention is to reflect the temperature change to flow the concave lens group 1 to more accurately determine the dust concentration.

Referring to the actual operation, first, light of the transmitting element is output through the third concave lens 1c installed at the center of the concave lens group 1.

When the ambient temperature rises, the shape memory spring expands and is positioned on the right side of the third concave lens 1c, and at the same time, the second concave lens 1b having a recessed angle lower than that of the third concave lens 1c is located at the position of the transmitting element. Accordingly, the light output of the transmitting element 2 is lowered and output. When the ambient temperature decreases, the shape memory spring 3 contracts and is positioned on the left side of the third concave lens 1c, and at the same time, the fourth concave lens 1d having a depression angle higher than that of the third concave lens 1c is transmitted. At the position of the device 2, the light output of the transmission device 2 is increased to output.

As described above, according to the present invention, the shape memory spring 3 automatically expands and contracts in response to the ambient temperature, thereby facilitating a change in the amount of light according to the movement of the dust, and thus determining a more accurate dust concentration, and providing a more accurate output. Is done.

On the other hand, the present invention is configured so that the transmission control unit 8 can determine the most accurate dust concentration by forcibly moving the concave lens group 1 in accordance with the dust concentration, even if there is no temperature change, the amount of light of the transmission element according to the dust concentration By adjusting, it is possible to determine the exact dust concentration.

That is, in the present invention, when the dust measurement control unit C outputs a control signal in order to facilitate the change of the amount of light of the infrared transmission means, the transmission control unit 8 recognizes this and drives the heat generating means 6 and the thermoelectric element 7. The most appropriate infrared transmission was made.

First, the infrared light is output through the third concave lens 1c, which is basically installed at the center of the concave lens group 1, and when the infrared light needs to be reduced a little, the transmission control unit 8 generates the heating means 6. 2) concave lens group 1 is moved but the second concave lens is installed on the right side of the third concave lens 1c because the shape memory spring is expanded and the transmitting element 2 is fixed. As the lens 1b moves to the position of the transmitting element 2, the output light of the transmitting element is output through the second concave lens.

When the infrared light needs to be reduced and outputted more, the transmission control unit 8 operates the heat generating means 6 to generate more heat so that the shape memory spring 3 expands more, and thus the concave lens group 1 ) Moves, but the first concave lens (1a) is heated to move to the position of the transmitting element (2), so that the light of the transmitting element (2) is output through the first concave lens (1a).

When the infrared light needs to be raised and output, the transmission control unit 8 drives the thermoelectric element 7 to generate cooling heat so that the shape memory spring 3 is contracted. Accordingly, the concave lens group 1 is moved. The fourth concave lens 1d, on which the left side of the third concave lens 1c is provided, is located in the transmitting element, so that the light of the transmitting element 2 is output through the fourth concave lens 1d.

In addition, when the infrared light needs to be higher and output, the transmission control unit 8 drives the thermoelectric element 7 to generate more cooling heat, thereby causing the shape memory spring 3 to contract more. ) Is moved but the fifth concave lens 1e is moved to the position of the transmitting element 2, whereby the light of the transmitting element 2 outputs light through the fifth concave lens 1e.

In addition, the concave lens group is designed to vary the degree of output of the infrared light according to the depression angle of the central portion, the third concave lens (1c) is basically installed at the center of the operating rod to form a depression angle of 25 degrees.

The second concave lens 1b is used when the infrared light needs to be slightly reduced and output. The second concave lens 1b is provided on the right side of the third concave lens 1c to form a depression angle of 15 degrees.

In addition, the first concave lens 1a is used when the infrared light is to be reduced and output more. The first concave lens 1a is installed at the right side of the second concave lens 1b and forms a depression angle of 5 degrees.

In addition, the fourth concave lens 1d is used in the case where the infrared light is to be further raised and output, and is installed on the left side of the third concave lens 1c to form a depression angle of 35 degrees.

In addition, the fifth concave lens 1e is used when the infrared light needs to be increased to output more, and is installed on the left side of the fourth concave lens 1d to form a depression angle of 45 degrees.

110: genetic information receiver
120: survey data receiving unit
130: gene DB
140: skin function gene grade determining unit
150: Determination of suitable cosmetics selection
160: cosmetic DB

Claims (6)

delete delete delete Gene information receiving unit 110 for receiving and outputting the genetic information of the subject;
A questionnaire data receiver 120 for receiving and outputting response data of the subject to the questionnaire items;
A gene DB 130 for storing expression information of skin function genes;
A cosmetic DB 160 for storing information on skin functional cosmetics;
A skin function gene grading unit 140 for comparing the gene information received by the gene information receiving unit 110 with the gene DB 130 to determine a skin function gene grade of the subject;
A suitable cosmetic selection determining unit 150 for selecting and selecting based on the cosmetic DB 160 to improve the skin corresponding to the skin function gene grade determined by the skin function gene grading unit 140;
The dust measuring means 1000 for measuring and transmitting whether the fine dust in the open air to the suitable cosmetic selection determining unit is greater than the reference, and to include chitosan, alginic acid, beta glucan, gamma-PGA in the suitable cosmetic selection determining unit Including;

The dust measuring means 1000,
Infrared ray transmitting means (A) for emitting infrared rays, and infrared ray receiving means for facing the infrared ray transmitting means and receiving the light emitted from the infrared ray transmitting means and determining dust inflow according to the amount of the received amount (B) and a dust measuring control unit (C) for controlling the input voltage of the infrared transmitting unit (A) to increase when the output voltage of the infrared receiving unit (B) is smaller than a set value;
The infrared transmitting means (A),
A concave lens group in which a plurality of concave lenses are mounted to limit the output of infrared rays;
An infrared ray transmitting element proximate to the concave lens group and outputting infrared rays;
It is installed on one side of the concave lens group to flow the concave lens group to adjust the infrared output, but if the ambient temperature is high according to the change in temperature, the concave lens group flows to the left to pass infrared light through the lens with a low depression angle A shape memory spring which controls the output to be high and controls the infrared output to be lowered by passing the concave lens group to the right when the ambient temperature is low and allowing infrared light to pass through the lens having a high depression angle;
Located on the right end of the shape memory spring customized cosmetic recommendation system using a big data and personal skin information comprising a fixed portion for supporting the movement of the shape memory spring. delete The method of claim 4, wherein
The infrared transmitting means (A),
A housing accommodating the shape memory spring and the fixing part;
It is installed inside the housing, but installed on one side of the shape memory spring forcibly expands the shape memory spring through heat to move the concave lens group to the left, thereby allowing infrared light to pass through the lens with a low depression angle to output infrared light Heating means for inducing this force to be raised;
It is installed on the inside of the housing but installed on the other side of the shape memory spring to transfer the cooling heat to force the shape memory spring to contract to move the concave lens group to the right, thereby allowing the lens and the infrared rays with high depression angle to pass through A thermoelectric element for inducing an infrared output to be forcibly lowered;
It is electrically connected to the heat generating means and the thermoelectric element, and if there is a lot of dust control to operate to increase the infrared output, and if there is little dust including a transmission control unit for controlling to lower the infrared output by operating the thermoelectric element; Personalized cosmetic recommendation system using big data and personal skin information.

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