KR101555636B1 - Multiple division type cosmetics providing method using gene analysis test - Google Patents

Abstract

The present invention relates to a multiple division-type cosmetics providing method using a gene analysis test, which divides the face of an examinee into multiple areas, analyzes skin conditions and characteristics of the divided areas using a gene test and the like, and provides cosmetics customized for each area based on a result of the analysis to improve the skin conditions, thereby facilitating more detailed skin care. The multiple division-type cosmetics providing method using a gene analysis test includes the steps of: generating a digital image by photographing the face of an examinee using a photographing unit; setting multiple areas divided into a forehead area, an area around eyes, a nose area, a left check area, a right check area, an area around mouth, and a jaw area by analyzing the digital image using an image analyzing unit; determining whether the skin type of each of the multiple areas is a moisturizing-type, a wrinkle-type, a sensitive-type, or a whitening-type by carrying out a gene test on the skin of each of the multiple areas using a gene testing unit; making, by a cosmetics making unit, cosmetics for skin improvement of each of the multiple areas based on skin types determined by the gene testing unit; providing, by a container providing unit, a cosmetics container having multiple divided storage spaces corresponding to each of the multiple areas; and providing, by a dispenser, the made cosmetics into each of the storage spaces of the cosmetics container.

Description

TECHNICAL FIELD [0001] The present invention relates to a method for providing cosmetics using multi-

The present invention relates to a method of providing cosmetics, and more particularly, to a method of providing cosmetics, in which the face of a subject is divided into multiple regions, and skin conditions and characteristics are analyzed using genetic tests or the like for each divided region, The present invention relates to a method of providing a multi-segmented cosmetic product using a genetic test that enables more detailed skin care by supplying customized cosmetics for each area.

Generally, human skin has different skin condition for each individual. In particular, even skin types of the same age and the same skin type can vary greatly depending on the internal and external environment of each individual. As the scientific civilization develops, there are more and more cases in which the skin is severely affected by exposure to various polluted environments, exposure to ultraviolet rays due to destruction of the ozone layer, various stresses, and the like, resulting in deterioration of skin function and even skin troubles . Therefore, there is an increasing tendency for users to have a desire for functional cosmetics that can improve or maintain skin condition.

However, at present, it is difficult to obtain complete trust in the skin condition information because the recognition of the skin condition mainly for each user is a degree of understanding the skin condition of the user through simple skin test and simple skin test. In addition, functional cosmetics currently on the market are not aimed at individuals, but are universal. Therefore, there are many limitations in finding suitable cosmetics for users.

Conventionally, a method of providing customized cosmetics by measuring the skin condition includes a method of analyzing the state of skin wrinkles by using an image analyzer system using a simulating plate in the case of wrinkles in order to check the current skin condition of a user, In the case of whitening, a change in erythema or skin color is measured using a mexameter and a colorimeter. In the case of skin moisturizing, a moisturizing amount is measured mainly by using a corneometer, In the case of skin elasticity, a cutometer is used to measure skin elasticity.

These measurements show the physical condition of the skin surface as a simple numerical value and may vary depending on the program to be measured, so that there is a risk of errors in evaluating the degree of improvement of the inspectors. In addition, in the case of the visual evaluation of the tester and the evaluation of the questionnaire of the inspected person, the subjective aspect plays a major role, which makes it difficult to objectively and precisely evaluate the skin condition of the subject. Therefore, providing customized cosmetics to users through these measurement methods has many limitations.

Furthermore, since the system measures and measures the state of the entire face of the user's face, there is a limitation in that it is possible to uniformly prescribe the entire face area of the user and to perform detailed management.

Korean Patent Publication No. 2007-0100158 (Oct. 10, 2007)

Accordingly, the present invention has been made to solve the above-mentioned conventional problems, and an object of the present invention is to provide a method and apparatus for dividing a face of a subject into multiple regions, The present invention provides a method of providing a multi-segmented cosmetic using a genetic test that enables more detailed skin care by supplying customized cosmetics to each region so as to improve the skin condition based on the result of analysis.

According to an aspect of the present invention, there is provided a method for providing cosmetics, the method comprising: generating a digital image by photographing a face of a subject to be examined with a photographing unit; Analyzing the digital image to divide the digital image into multiple regions divided into a forehead, an eye, a nose, a left ball, a right ball, a mouth, and a jaw region; Providing a cosmetic container having a plurality of accommodating spaces divided so that a container supply portion corresponds to each of the regions of the multiple regions; And the cosmetics dispenser supplies cosmetics differentiated according to the respective receptacle spaces of the cosmetics container.

Here, the genetic test of the skin of each region of the multiple regions may be examined to determine whether the skin type of each region of the multiple regions is moisturizing, wrinkling, sensitive or non-moisturizing. And selecting a functional cosmetic for each region of the multi-region based on the skin type determined by the gene analysis unit, thereby manufacturing a cosmetic product to be supplied by the dispenser.

Further, the cosmetic container may have a peripheral contour of a shape corresponding to a human face shape, and the plurality of accommodating spaces may be divided into a shape isolated by a partition wall.

The image analyzer may analyze the digital image to calculate the area of each area of the multi-area, and the dispenser may vary the amount of cosmetics according to the area ratio of each area of the multi- And is separately supplied to each containing space of the cosmetic container.

The method may further include analyzing a digital image obtained by the photographing of the photographing unit and evaluating a skin trouble level for each face region of the member, wherein the step of evaluating the skin trouble level includes: 1) Separating the image into three colors of red, green, and blue and evaluating the level; 2) a step of calculating the surface area area in which the pigmentation is expressed in the image analysis unit and evaluating the level thereof.

When the photographing unit photographs the face of the examinee, the brain wave of the inspected person is measured by the brain wave measuring unit. When the measured brain wave belongs to the alpha wave state in the frequency band of 8 to 13 Hz indicating the relaxed state, And a digital image is generated.

When the brain wave of the inspector is not in the? Wave state, the EEG stabilizer induces the brain wave of the inspector to the? Wave by the light and the sound, and when the inspector's brain wave is converted into the? Wave state, And a digital image is generated.

The method of providing a multi-divisional cosmetic product according to the present invention divides the face of the inspector into multiple regions, analyzes the skin condition and characteristics for each region, and improves the skin condition based on the result, It is possible.

In addition, the present invention uses an intuitive form of cosmetic container having a human face contour and a plurality of accommodating spaces divided in correspondence to the divided regions inside, Can be applied.

1 is a conceptual diagram of a method of providing cosmetics according to an embodiment of the present invention;
2 is a view showing a state in which a face of a person to be inspected is divided into multiple regions through image analysis in a method of providing cosmetics according to an embodiment of the present invention;
3 is a flowchart for explaining a configuration of a cosmetic product providing method according to an embodiment of the present invention.
4 is a block diagram of a system for implementing a method of providing cosmetics according to an embodiment of the present invention
5 is a view for explaining an EEG measuring unit and an EEG unit in a method of providing cosmetics according to an embodiment of the present invention;
6 is a view for explaining the state of the brain waves of the examinee in the method of providing cosmetics according to the embodiment of the present invention.
7 is a view for explaining a digital image of the inspector in the method of providing cosmetics according to the embodiment of the present invention.
8 is a view for explaining multi-region division and skin trouble level evaluation by image analysis in the method of providing cosmetics according to the embodiment of the present invention
FIG. 9 is a perspective view of a cosmetic container designed to contain customized cosmetics in different areas according to the method of providing cosmetics according to an embodiment of the present invention.
FIG. 10 is a side view of the dispenser and the container supply unit used in the method of providing cosmetics according to the embodiment of the present invention
11 is a bottom view of the dispenser used in the method of providing cosmetics according to the embodiment of the present invention
FIG. 12 is a perspective view showing a state in which customized cosmetics according to regions are provided for each space accommodated in the cosmetics container in the method for providing cosmetics according to the embodiment of the present invention. FIG.

A method of providing a multi-divisional cosmetic product according to embodiments of the present invention will be described in detail with reference to the accompanying drawings. The present invention is capable of various modifications and various forms, and specific embodiments are illustrated in the drawings and described in detail in the text. It is to be understood, however, that the invention is not intended to be limited to the particular forms disclosed, but on the contrary, is intended to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the invention. Like reference numerals are used for like elements in describing each drawing. In the accompanying drawings, the dimensions of the structures are enlarged to illustrate the present invention, and are actually shown in a smaller scale than the actual dimensions in order to understand the schematic configuration.

Also, the terms first and second, etc. may be used to describe various components, but the components should not be limited by the terms. The terms are used only for the purpose of distinguishing one component from another. For example, without departing from the scope of the present invention, the first component may be referred to as a second component, and similarly, the second component may also be referred to as a first component. On the other hand, unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries are to be interpreted as having a meaning consistent with the contextual meaning of the related art and are to be interpreted as either ideal or overly formal in the sense of the present application Do not.

FIG. 1 is a conceptual diagram of a method of providing cosmetics according to an embodiment of the present invention. FIG. 2 is a view showing a state in which a face of a subject is divided into multiple regions through image analysis in the method of providing cosmetics according to an embodiment of the present invention to be.

As shown in FIG. 2, the method of providing cosmetics according to an embodiment of the present invention is not limited to uniformly managing the entire face of the inspector, The present invention provides a cosmetic product differentiated according to the skin characteristics of each region by using the divided cosmetic container designed to correspond to the divided multiple regions after divided into multiple regions of the right ball, So as to manage and improve the skin condition.

Hereinafter, a method of providing cosmetics according to an embodiment of the present invention will be described in detail.

FIG. 3 is a flow chart for explaining a configuration of a cosmetic product providing method according to an embodiment of the present invention, and FIG. 4 is a configuration diagram of a system for implementing a cosmetic product providing method according to an embodiment of the present invention.

As shown in the figure, the method of providing cosmetics according to an embodiment of the present invention includes steps of measuring EEG waves S101, generating digital images S102, dividing multi-regions 103, A trouble type evaluation step S104, a skin type determination step 106 using a genetic test, a cosmetic manufacturing step S107, a cosmetic container supply step S108, and a cosmetic supply step S109. The method of providing cosmetics according to the embodiment of the present invention is not to uniformly manage the entire face of the examinee through such progressive steps but may divide the face of the examinee into subdivisions and then divide the face of the examinee into sub- By providing differentiated cosmetics, the skin condition can be more finely managed and improved. To this end, as shown in FIG. 4, a system including a photographing unit, an EEG measuring unit, an image analyzing unit, a genetic testing unit, an EEG unit, a controller, a database, a cosmetic manufacturing unit, a container supplying unit, and a dispenser is used.

Hereinafter, a method of providing cosmetics according to an embodiment of the present invention will be described in detail with reference to the above steps.

The EEG measurement step S101 can be regarded as a preparatory step for obtaining a more consistent result through the digital image generation step S102 and enables a digital image to be generated only in a comfortable state in which the inspector is stable . In the EEG measurement step, the brain wave of the examinee is measured by the EEG measuring unit 140 as shown in FIG. As is known, human brain wave states can be classified into delta (δ), theta (θ), alpha (α), and β (β) states. As shown in FIG. 6, when a person is comfortable, the frequency band is relatively low in an? -Wave state having a frequency band of 8 to 13 Hz as in (B). However, when a person is excited, a? -Wave state having a frequency band of 13 to 50 Hz is changed to a higher-level frequency band as compared with the? -Wave state. In such a? -Phase state, the face skin color becomes redder than usual. Therefore, in order to obtain a more accurate digital image and image analysis result, it should be avoided when the inspector's EEG state is in the excited state and photographed in the stable state. Further, when the subject's brain wave is not in the? -Wave state, the brain wave stabilizer 130 can induce the brain wave of the subject to be inspected by light and sound into the? Wave and quickly convert it into the? Wave state. The EEG stabilizer 130 may be used by connecting the EEG devices currently in use for learning and therapy with the EEG detector 140.

5, the EEG measuring unit 140 includes an EEG detector 141 that directly contacts the head and senses an EEG signal and converts it into an electrical EEG signal, And an A / D converter 143 for converting an analog type EEG signal input from the amplifier 142 into a digital EEG signal and outputting the EEG signal. Here, the EEG detector 141, the amplifier 142, and the A / D converter 143 constituting the EEG measuring unit 140 can be easily obtained in the market, and the EEG measuring unit 140 may be constructed by combining them Since it is a known technology, a further explanation will be omitted.

Thereafter, the digital image generation step (S102) proceeds. In the digital image generation step (S102), the face of the examinee is photographed by the photographing unit, and the face of the examinee is generated as a digital image as shown in FIG. As the digital color video camera, the photographing unit may be a TRI-CCD type color camera, in particular, a digital still camera commercially available from SONY, or a D70S type digital still camera sold by NIKON. At this time, in order to acquire a digital image, a skin region to be analyzed is illuminated by an illumination device, which is illuminated with white light or ultraviolet light. And, as described above, the subject's EEG should be photographed as belonging to the α-wave state in the frequency band of 8 to 13 Hz, which indicates relaxed state. If the subject's EEG is not in the α-wave state, The brain wave of the inspector is guided to the alpha wave, and when the brain wave of the inspector is converted into the alpha wave state, the photographer shoots the face of the inspector. However, the photographing of the face of the examinee is preferably performed on the side rather than the front, which is desirable for accurate image analysis in the future.

Thereafter, the multi-region dividing step 103 proceeds. In the multi-region dividing step 103, the image analyzing unit analyzes the digital image generated through the previous step and obtains seven digital images divided into forehead, eyes, nose, left ball, right ball, mouth, It is divided into multiple areas. Such an area may be divided into eight multi-areas including a tree area.

Thereafter, an area-by-area calculation step (S103) is performed through image analysis. In the area-by-area calculation step (S103), images classified into seven or eight multi-areas divided into forehead, eye, nose, left ball, right ball, mouth, . When the area of each area is calculated in this manner, it is possible to differentiate and supply the amount of cosmetics to be used for each area according to the area ratio.

Thereafter, the skin trouble level evaluation step (S104) proceeds. In the skin trouble level evaluation step (S104), the image analysis unit analyzes the digital image and evaluates the skin trouble level for each divided region. First, digital images are separated into three colors, red, green, and blue, and their levels are evaluated. Second, the surface area of wrinkles, wrinkles, stains, dark circles, and pigmentation is calculated and evaluated. By evaluating the skin trickle level, it is possible to grasp the trouble and the trouble area T existing in the forehead area, for example, as shown in FIG. For reference, a specific method for evaluating such a skin trouble level may be performed using known techniques such as Korean Patent Laid-Open Publication No. 2008-0060260 (2008.07.01). For example, according to the embodiment disclosed in Korean Patent Laid-Open Publication No. 2008-0060260, a digital image can be converted into three color levels, namely, R, Green, and blue levels, referred to as G, B, and based on the color level, the average gradation of the image, the defect in the skin, such as wrinkles, wrinkles, stains, dark circles, pigmentation, It is possible to calculate the deviations of the gradation for the pixel set of the image as a parameter representing the surface area of the skin and the homogeneity of the skin, It also tells you that you can use mathematical filters included in image analysis software to remove specific colors or remove spurious noise such as reflections from digital images.

Thereafter, the skin type determination step 106 using the genetic test proceeds. In the skin type determination step (106), a genetic checker gene test is performed on the skin of each of the multiple regions to determine whether the skin type is moisturizing, wrinkling, sensitive, . To this end, the genetic testing unit may include one or more single nucleotide polymorphism markers selected from single nucleotide polymorphism (SNP) markers for determining whether the skin type is moisturizing, and single nucleotide polymorphism markers for determining whether the skin type is wrinkles. At least one single nucleotide polymorphism marker selected from among single nucleotide polymorphism markers determining whether the skin type is sensitive and at least one single nucleotide polymorphism marker selected from among single nucleotide polymorphism markers determining whether the skin type is whitening, Diagnostic kits having a diagnostic composition comprising a probe capable of detecting markers for these skin type diagnoses or agents capable of amplifying using a single nucleotide polymorphic marker can be used. The diagnostic kit may be provided with an RT-PCR kit or a DNA chip kit.

The method of collecting the skin cells of the examinee is not particularly limited, but it is preferable to use a tape stripping method in which a cellophane tape is stuck to the forehead, eyes, cheeks, Skin cells can be harvested. In addition, the process of extracting the gene from the skin cells includes extracting the total RNA or DNA of the skin cells from the collected skin cells. (See Rita Wong, Vynga Tran, Vera Morhenn, She-pin Hung, Bogi Andersen, Elaine Ito, G. Wesley Hatfield, and Nicholas R. Benson. Use of RT-PCR and DNA Microarrys to Characterize RNA Recovered by Non-Invasive Tape Harvesting of Normal and Inflamed Skin., J Invest Dermatol 123: 159-167, 2004.)

On the other hand, when such a marker and a diagnostic kit are provided, (a) obtaining DNA from skin cells collected from the skin of each area of the examinee's face, (b) extracting DNA from the DNA obtained in step Amplifying the polymorphic site of the polymorphic marker or hybridizing it with the probe, and (c) identifying the base of the amplified or hybridized polymorphic site of step (b) You will be able to grasp the different skin types.

However, the method of collecting the skin cells of the examinee is not particularly limited, but preferably, the skin cells can be collected through a tape stripping method in which a cellophane tape is attached to the skin of the area and the skin is peeled off . In addition, the process of extracting the gene from the skin cells includes extracting the DNA of the skin cells from the collected skin cells. (See Rita Wong, Vynga Tran, Vera Morhenn, She-pin Hung, Bogi Andersen, Elaine Ito, G. Wesley Hatfield, and Nicholas R. Benson. Use of RT-PCR and DNA Microarrys to Characterize RNA Recovered by Non-Invasive Tape Harvesting of Normal and Inflamed Skin., J Invest Dermatol 123: 159-167, 2004.)

In the case of techniques for determining whether the skin type is moisturizing, wrinkling, sensitive or non-skinning using the genetic test, the technique for determining the state is disclosed in Korean Patent Laid-Open Publication No. 2013-0016009 (2013.02 .14) can be explained in more detail.

Korean Patent Laid-Open Publication No. 2013-0016009 discloses single base polymorphic markers which can judge whether the skin type is moisturizing, wrinkle-sensitive, sensitive or non-skin-sensitive. In other words, the single nucleotide polymorphism (SNP) markers for determining whether the skin type is moisturizing include 5 to 100 consecutive sequences including 129412726 base of human chromosome 3 (rs28459381) A polynucleotide consisting of a DNA sequence that is complementary to the DNA sequence; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29663843th base of human chromosome 6, C or T (rs1233387), the 29663843th base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29820388 base of the human chromosome 7, C or T (rs174922), and the 29820388 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29820850 base of the human chromosome 7, T or C (rs174923), and the 29820850 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 141425903 base of human 7 or C14 or base 15142903 base (rs12666982); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29105682 base of human chromosome 3 is G or A (rs9818278), and the 29105682 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 125175173 base of the human chromosome 5, T or C (rs12109492), including the 125175173 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 59132422 bases of human chromosome 12 (rs12228176), which is C or T, and 59132422 bases; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 52868639 base of the human chromosome 2, C or T (rs7581434), and the 52868639 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 5285619595 base of human human chromosome 2, G or T (rs7573204), and the 52856195 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 59106853 base of human chromosome 12, T or C (rs3923917), and the 59106853 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 4600440 base of the human chromosome 20 (A rs28702443) and the 4600440 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29914639 base of the human tenth chromosome is G or A (rs4572039), and the 29914639 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 95705228 base of the human eighth chromosome (rs2890805), the 95705228 base being C or T; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 25590529 base of the human 15th chromosome (rs25590529), which is A or G, and the 25590529 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 107093501 base of the human 6 th chromosome, G or A (rs783400), the 107093501 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 25586993 base of the human 15th chromosome (rs3098582) with C or T, the 25586993 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 25585078 base of the human 15th chromosome (rs12591822) with T or C; And complementary polynucleotides thereof. The term " polynucleotide "

In addition, the single nucleotide polymorphism markers for judging whether or not the skin type is wrinkle include 5 to 100 consecutive DNAs including the 24551208 base (rs2711118) in which human 24551208 base is A or G (rs2711118) A polynucleotide consisting of a sequence; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 76839279 base of the human chromosome 5 (A) or G (rs4273585), and the 76839279 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 208672298 base of C on human chromosome 1 (rs11119496) and the 208672298 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 52738724 base of the 52738724 base of human human chromosome 20 (rs6127255), which is T or C; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 27346024 base of human chromosome 7 (rs2158769) with C or T, and 27346024 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 47954398 base of human chromosome 15 is A or C (rs16963008), said base 47954398 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 101951190 base of the human chromosome 3, T or C (rs1048364), the base 101951190 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 101936968 base of human chromosome 3 is G or A (rs931206), and 101936968 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 106740691 base of human chromosome 13 (Ts or C) (rs9555341), and the 106740691 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 122472521 base of human chromosome 10, C or T (rs10886747), and the 122472521 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 17733099th base of human chromosome 4, G or T (rs4538426), said 177330499 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 177322010 base of human chromosome 4 (c) or C (rs2170576), said base 177322010 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 51222720 base of the human chromosome 12, G or A (rs11170170), and the 51222720 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 107123424 base of the human chromosome 6, T or C (rs3747790), and the 107123424 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 68751073th base of human chromosome 11 (rs7931342) with T or G, and the 68751073th base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 199554152 base of human chromosome 1 is C or T (rs916398), said 199554152 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 72820331 base of human chromosome 10, G or A (rs10999801), and the 72820331 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 72805925 base of the human chromosome 10 (rs1417210), which is A or G, and the 72805925 base; And complementary polynucleotides thereof. The term " polynucleotide "

In addition, the single nucleotide polymorphism markers for determining whether the skin type is sensitive include 5-100 consecutive DNA sequences containing the 153923073 base of human chromosome 6 (rs576496) with C or T (rs576496) A polynucleotide consisting of: A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 111003744 base of the human chromosome 9, C or T (rs7021903), and the 111003744 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 108135402 base of the human chromosome 6, which is T or C (rs6921267), and the 108135402 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 113245651 base of human chromosome 3 is G or A (rs7650263), and 113245651 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134456647 base of human human chromosome 2, G or A (rs16829881), and the 134456647 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134467821 base of human chromosome 2 (A rs2321546) with A or G, and the 134467821 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 63359260 base of the human chromosome 18, G or C (rs9957826), and the 63359260 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 4268219 base of human human chromosome 2, G or A (rs17018897), and the 4268219 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 46170608 base of human human chromosome 2, A or T (rs1868273), the 46170608 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 153943264 base of human chromosome 6, C or T (rs6920377), said 153943264 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 46175944 base of the human chromosome 2, G or C (rs4953307), and the 46175944 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 7547691616 base of human human chromosome 4 (Cs or T) (rs6446995), and the 75476916 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 79763138 base of the human chromosome 9, C or T (rs11145633), the 79763138 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 20125657th base of human chromosome 13, G or A (rs9506530), the 20125657th base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 111001210 base, wherein the 111001210 base of human chromosome 9 is C or T (rs7875754); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 36732263 th base of human human chromosome 2, G or T (rs11883493), and the 36732263 th base; And complementary polynucleotides thereof. The term " polynucleotide "

In addition, the single nucleotide polymorphic markers for judging whether the skin type is whitening include 5-100 consecutive DNAs (rs1100311) in which the 54189156 base of human chromosome 10 is T or C (rs1100311), the 54189156 base A polynucleotide consisting of a sequence; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 82834514 base sequence of the human chromosome 5 (G) or G (A) (rs1833890), and the 82834514 base sequence; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 55831811 base of the human chromosome 1, T or C (rs7526426), and the 55831811 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 191042669 base of human human chromosome 2, G or A (rs1019321), said 191042669 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54169046 base of C on human chromosome 10 (rs1238575) and the base 54169046 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 8282972792 nucleotide of human chromosome 5 (rs2652106) with G or T; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 43428336 base of human chromosome 13, G or A (rs7322264), and 43428336 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54196212 base of the human chromosome 10 (rs1082479), which is T or C, and the 54196212 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 191009613 base, wherein the 191009613 base of human chromosome 2 is A or G (rs9646748); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 55855971 base of human chromosome 1 (T) or T (C) rs1118219, including the 55855971 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134657139 base of human chromosome 3 is C or T (rs9865003), the 134657139 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 54182014 base of human chromosome 10 (Tg or G) (rs1100311), including 54182014 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54191096 base of human human chromosome 10, C or T (rs 1693307), and the 54191096 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 4860027 base (489005785) of human chromosome 6 with A or G (rs9405785); A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 79431934 base of human chromosome 4, G or T (rs1484344), and the 79431934 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 32866528 base of the human chromosome 14, G or A (rs8011225), and the 32866528 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 8396938686 base of human chromosome 1 (A rs3470503) and the 83969386 base; A polynucleotide consisting of 5-100 consecutive DNA sequences containing the 22067299 base of the human chromosome 16 (rs1164222) with T or G, and the 22067299 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 134656869 base of human chromosome 3 is C or T (rs2370246), the 134656869 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 191098371st base of human chromosome 2 (A rs1093145), which is A or G, and the 191098371st base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 188206372 base of the human chromosome 1 (rs1711758), which is G or A; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 191041973 base of human human chromosome 2, T or C (rs4340549), and the 191041973 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 96368401 base of the human chromosome 15, T or C (rs2845633), the 96368401 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54203366 base of human chromosome 10 (A) or G (rs1031101), and the 54203366 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 29970271 base of human human chromosome 8, G or A (rs6987138), and the 29970271 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 900218 base of C on human chromosome 20 (rs2223962), the 900218 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 3765524040 base of human 6 or G (A rs804846) comprising the 37655240 base; A polynucleotide consisting of 5-100 contiguous DNA sequences comprising the 235675961 base of human chromosome 2 (rs4277473) with A or G, and the 235675961 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 43418348 base of the human chromosome 13, T or C (rs9525880), and the 43418348 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 58468246 bases of human chromosome 5 (rs1006239), which is C or T, and 58468246 bases; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 54173326 base of human chromosome 10, G or A (rs996232), and the 54173326 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 244670509 base of human chromosome 1 (rs2340778), which is C or T, and the 244670509 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 158512290 base of the human chromosome 5 (A) or G (rs6556401), and the 158512290 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 17963006 base of human chromosome 8 (rs1763609) which is A or G, and 17963006 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 67559320 base of the human chromosome 17, T or C (rs9911193), and the 67559320 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 65093758 base of the human chromosome 16, T or C (rs1428106), and the 65093758 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 20186505 base of the human chromosome 9 (rs1456958) with T or G, and 20186505 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 20186466 base of human chromosome 9 with T or C (rs1456959), 20186466 base; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising the 20218652 base of the human chromosome 9 (rs321218), which is C or T; A polynucleotide consisting of 5-100 consecutive DNA sequences comprising 19969813 base of the human chromosome 9 (A rs1892011), said 19969813 base; And complementary polynucleotides thereof. The term " polynucleotide "

On the other hand, Korean Patent Laid-Open Publication No. 2007-0100158 (Oct. 10, 2007) discloses another method for determining whether the skin type is moisturizing, wrinkling, sensitive, or immovable through genetic testing. In particular, Korean Patent Laid-Open Publication No. 2007-0100158 discloses that the genes relating to moisturizing and elasticity are AQP3, HAS3, PIGA, FLG, DSP, DSC1, PPL, DSG1, LOR, CESN, IVS, TGM1, KRT14, KRT5, KRT6A, KRT1, MMP8, MMP13, NFκB, MMP10, MMP3, MMP2, MMP9, and the genes involved in whitening are TYR, TRP1, TRP2, MITF, MLANA, SILV, PAX3, SOX10 and TFAP2A, which are performed according to the conventional real-time PCR method known as the Taqman method with the highest reliability.

In order to determine the skin type, the degree of gene expression can also be measured using a DNA chip. The DNA chip is a device capable of simultaneous analysis of a large number of genes even with a very small amount of specimens and capable of analyzing genetic expression information very rapidly. The DNA Chip is prepared by putting hundreds to hundreds of thousands of DNAs in a very small space. The method of producing the DNA Chip and the method of measuring the DNA Chip are known in the art. According to the known method, Can be measured.

Thereafter, the cosmetic production step S107 proceeds. In the cosmetic manufacturing step (S107), the cosmetic manufacturing part selects cosmetic functional cosmetics which need to be supplemented so as to improve the skin of each area of the multi-areas based on the skin type determined through the previous step, Customized cosmetics are manufactured for each area. Here, the method of manufacturing cosmetics according to the skin type is disclosed in detail in Korean Patent Laid-Open Publication No. 2007-0100158 (Oct. 10, 2007).

Herein, the moisturizing and improving component may include 0.1 to 30% by weight of sodium hyaluronate, 0.1 to 20% by weight of phytosterols, 0.1 to 30% by weight of soybean ferment extract, 0.01 to 10 wt% of collagen, 0.1 to 30 wt% of collagen, 0.5 to 20 wt% of polysaccharides, 0.01 to 5.0 wt% of sphingolipids, [alpha] -hydroxy acid ), 0.5 to 20% by weight of urea, 0.5 to 20% by weight of 棺 -hydroxy acid, 1 to 10% by weight of urea and 0.1 to 30% by weight of 棺 -glucan May be used.

The wrinkle-improving component is preferably at least one selected from the group consisting of 0.04 to 1.0 wt% of adenosine, 1 x 10 < 2 > to 10 x 10 3 IU / g of retinol, 1 x 10 3 to 1 x 10 6 IU / g of retinyl palmitate, 0.1 to 20% by weight of vitamin C and derivatives, 0.1 to 20% by weight of vitamin E and its derivatives, 0.01 to 20% by weight of peptides, 0.005 to 0.2% of Coenzyme Q10, A perfluoropolyether of 1.0 to 20 wt%, an epidermal growth factor of 1 ppm or less, a ginseng extract of 0.1 to 10 wt% and a green tea extract of 0.1 to 20 wt% By weight, and the like.

The elasticity improving component added according to the expression amount of the gene related to elasticity is 0.1 to 20% by weight of vitamin C and its derivatives, 0.1 to 20% by weight of tomato extract (Lycopene), isoflavones, 0.5 to 20% by weight of pomegranate extract, 0.5 to 20% by weight of pomegranate extract, 0.1 to 10% by weight of polyphenols, 0.1 to 20% by weight of wild yam extract, sphingolipids, 5.0% by weight, and Peptides of 0.01 to 20% by weight.

The whitening improving ingredient is 0.1 to 20% by weight of vitamin C and its derivatives, 0.5 to 7% by weight of arbutin, 0.1 to 20% by weight of Mulberry extract, , 0.1 to 10% by weight of Ephedra sinica extract, and 0.1 to 20% by weight of Rooibos extract, based on the total weight of the extract of wild ginseng adventitious roots extract, One or more selected from the group consisting of

Thereafter, the cosmetic container supply step (S108) proceeds. In the cosmetic container supplying step (S108), as shown in FIG. 9, a cosmetic container 110 designed in a unique form for the cosmetic providing method of the present invention is used. As shown in FIG. 10, (CV) to the position where the dispenser 120 is installed. Here, the cosmetic container 110 has a circumferential outline of a shape corresponding to a human face shape and has a plurality of accommodating spaces divided into mutually isolated shapes by barrier ribs 9111 so as to correspond to the respective regions of the multiple regions It is a constitutive feature. That is, the cosmetic container includes a forehead area accommodation space 110a, an eye area accommodation space 110b, and an eye area accommodation space 110b corresponding to forehead, eyes, nose, left, right, A left ball area accommodating space 110d, a right ball area accommodating space 110e, a mouth area accommodating space 110f, a jaw area accommodating space 110g, and a neck area accommodating space 110h. .

In addition, the cosmetic container 110 includes a cover 112 covering a body provided with a receiving space. On the upper surface of the cover 112, a name of the inspector and a label 112a ) Are provided so as to have the identifiability. Since the cosmetic container 110 having such a configuration corresponds to the divided multiple regions of the face of the inspector, it is convenient to separate and accommodate cosmetics manufactured for each region of the multiple regions. Further, the staff of the skin care center can more easily apply the cosmetics provided for each face region of the examinee using the intuitive form of the cosmetic container 110. (Of course, the inspector himself may make up his own cremation.)

Thereafter, the cosmetic supply step (S109) proceeds. In the cosmetic supply step (S109), the dispenser (120) is manufactured in the previous step as shown in FIG. 10, and supplies the cosmetic for each area of the supplied multi-zone to the cosmetic container. Under the control of the controller, the dispenser 120, which is used at this time, differentially supplies the cosmetics container 110 to the respective accommodating spaces of the cosmetics container 110 by varying the amount of the cosmetics according to the area ratio of each area of the multi-region calculated by the image analyzing unit. 10 and 11, the dispenser 120 includes a plurality of nozzles 123 at the lower portion of the body 121 so as to match the number and positions of the respective receiving spaces of the cosmetic container. 11, the forehead area 110a, the eye area 110b, the nose area 110c, the left ball area 110d, and the right ball area 110e, The dispenser 120 is also provided with a forehead area nozzle 123a, an eye area nozzle 123b, a nose area nozzle 110b, and a nose area nozzle 110b in correspondence with the mouth area receiving space 110f, the jaw area receiving space 110g, Eight nozzles including a nozzle area 123c, a left ball area nozzle 123d, a right ball area nozzle 123e, a mouth area nozzle 123f, a jaw area nozzle 123g, and a neck area nozzle 123h are arranged Can be confirmed. According to the configuration in which the dispenser 120 includes the plurality of nozzles 123, cosmetics for each face region of the inspector can be quickly supplied to the cosmetic container at once. When the cosmetic supply step (S109) proceeds, customized cosmetics for each area prescribed for each face area are accommodated in each containing space in the cosmetic container 110, and after the inspected person is labeled, the inspector belongs to the member It will be transported to the collection center so that it can be delivered to each management center or the inspector's home.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. It is clear that the present invention can be suitably modified and applied in the same manner. Therefore, the above description does not limit the scope of the present invention, which is defined by the limitations of the following claims.

110: cosmetic container 111: partition wall
112: cover 120: dispenser
123: Nozzle 130: EEG control unit
140: EEG measurement unit

Claims (7)

Capturing a face of the inspector as a photographing part to generate a digital image;
Analyzing the digital image to divide the digital image into multiple regions divided into a forehead, an eye, a nose, a left ball, a right ball, a mouth, and a jaw region;
Providing a cosmetic container having a plurality of accommodation spaces divided by a partition so that the container supply portion corresponds to the respective regions of the multiple regions;
Wherein the cosmetics dispenser supplies cosmetics differentiated according to the respective receptacle spaces of the cosmetics container,
Wherein the image analyzing unit analyzes the digital image to calculate an area of each area of the multi-area, and the dispenser varies the amount of cosmetics according to the area ratio of each area of the multi-area calculated by the image analyzing unit, Wherein the cosmetics are separately supplied to the respective accommodation spaces of the cosmetics. The method according to claim 1,
Determining whether the skin type is moisturizing, wrinkle-sensitive, sensitive or non-skin-sensitive for each region of the multi-region by performing genetic test for the skin of each region of the multi-region;
Further comprising the step of producing a cosmetic product for skin improvement according to the skin type determined by the genetic testing unit, by the cosmetic manufacturing unit, for each region of the multi-region. The method according to claim 1,
Wherein the cosmetic container has a circumferential contour of a shape corresponding to a shape of a human face and the plurality of accommodating spaces are divided into a shape isolated by a partition wall. delete The method according to claim 1,
Further comprising the step of analyzing the digital image obtained by the photographing of the photographing unit to evaluate a skin trouble level for each face region of the inspected person,
The step of evaluating the skin trouble level comprises:
1) separating a digital image into three colors of red, green, and blue in an image analysis unit and evaluating the level;
2) evaluating the level of the surface area in which the pigment is deposited in the image analysis unit. 6. The method of claim 5,
When the photographing unit photographs the face of the inspected person, the EEG wave of the inspected person is measured by the EEG measuring unit, and when the measured EEG belongs to the alpha wave state of the 8 to 13 Hz frequency band indicating the relaxed state, And a digital image is generated by performing photographing. The method according to claim 6,
When the brain waves of the inspector are not in the? -Wave state, the EEG stabilizer induces the brain waves of the examinee by the light and sound, and when the brain waves of the examinees are converted into the? -Wave state, Thereby generating a digital image.

Images