KR102073057B1 - Removing reagent for quick peeling tattoo sticker - Google Patents

Abstract

The present invention relates to a composition of a tattoo sticker remover for fast removal without irritation from the skin to which the tattoo sticker is attached. Accordingly, the removal composition has an effect of quickly removing the tattoo sticker without irritation on the skin, anyone of all ages can easily and comfortably enjoy the tattoo sticker.

Description

Removing reagent for quick peeling tattoo sticker}

The present invention relates to a composition for rapid removal without irritation from the skin with a tattoo sticker. More specifically, the present invention relates to a composition for quickly removing a tattoo sticker containing polysorbate-60 as an active ingredient in a mixture of aloe extract, agave extract, and zinnia herb in ethanol and mixed in a constant ratio. .

In general, tattoo stickers are complementary to the disadvantages of tattoos (tattoos, permanent tattoos), henna, etc. Recently, with the development of printing techniques, adhesives that can be applied to the skin without side effects have been developed, and the use of tattoo stickers is increasing.

However, if you don't like the attached area, or if you try to peel your tattoo sticker off your skin quickly for various reasons, it won't be properly removed with a normal detergent or cosmetic remover. In addition, the use of a bath towel may cause rashes on the skin due to excessive irritation.

Recently, natural materials with cactus are widely used as raw materials for cosmetics and beauty products, and these materials have high biocompatibility and affinity, and thus they are widely used for moisturizing, antioxidant, whitening, wrinkle improvement, and exfoliation. It is becoming. Among them, aloe, baeknyeoncho and agave are used as raw materials for exfoliating cosmetics by stimulating the activity of proteolytic enzymes.

The present invention focuses on the removal of the tattoo sticker adhered to the skin easily and quickly while minimizing the irritation due to the friction of the skin by developing a composition that does not irritate the skin to remove the tattoo more universal and widely available To provide.

Patent No. 10-1380902 (Easy Cleansing Tissue for Face Washing) includes a pulp paper for skin tissue and a face wash impregnated with the pulp paper, and the face wash includes a solvent, a surfactant, a humectant, and a perfume. , Preservative, antistatic agent, chelating reagent, menthol, pH adjuster, skin conditioner, and colorant are mixed to remove skin wastes and cosmetics cleanly to prevent trouble and aging of skin caused by wastes and cosmetics. In addition, the tissue can be provided to keep the skin healthy and easy to use.

Patent No. 10-1592242 (multifunctional cleansing tissue for cosmetic removal and skin care containing vegetable collagen and a method for preparing thereof) comprises panthenol, centilla asiatica extract, horseshoe mushroom extract, vitamin C derivatives and hyaluronic acid, The present invention relates to a cosmetic cleansing tissue including a cosmetic comprising a biodegradable porous foam and a cosmetic composition impregnated therein and a liquid cleanser containing pulp paper and vegetable collagen, and a method for preparing the same. Multi-functional cleansing for skin removal and skin care that includes basic cosmetic functions such as skin toner and skin lotion that have skin protection effect such as activating skin collagen formation, minimizing skin irritation, soothing and moisturizing as well as collagen It is about tissue and can maximize portability of toiletries and wash face with water It can effectively protect the skin even in difficult situations and provides the effect of minimizing the skin irritation that occurs during the various stages of washing and applying basic cosmetics after washing.

Korean Patent No. 10-1717496 (Cleansing Cosmetic Composition) includes bamboo water, lipophilic and hydrophilic solvents, scrub beads, moisturizers, surfactants, builders, thickeners and purified water, and enhances skin health while simultaneously removing skin dead skin cells. The present invention relates to a cleansing cosmetic composition capable of expecting effects and the like.

Patent No. 10-1571387 (Cosmetic composition containing agave leaves complex extract) relates to a cosmetic composition containing agave leaves complex extract, desalted lava seawater, cornflower extract, perilla extract, tricolor violet extract, and agave leaf extract It relates to a cosmetic composition having excellent skin moisturizing effect and moisture control effect, including as an active ingredient.

However, since the prior art has no effect of removing tattoo stickers, there is a need for developing a remover capable of removing tattoo stickers.

Patent Registration No. 10-1645662 Patent Registration No. 10-1380902 Patent Registration No. 10-1592242 Patent Registration No. 10-1717496 Patent Registration No. 10-1571387

With the necessity of developing a remover capable of quickly removing tattoo stickers from the skin without irritation, the inventors of the present invention have completed the remover capable of removing tattoo stickers quickly without irritating the skin. It is therefore an object of the present invention to provide a remover for quickly removing tattoo stickers without irritating the skin.

In order to achieve the above object, the present invention includes a cactus and (plant) extract (Aloe, agave, baeknyeoncho) as an active ingredient, the mixture is aloe extract, agave extract, baeknyeoncho extract after dissolving in ethanol, It provides a composition for removing tattoo sticker prepared by adding a predetermined amount of polysorbate-60 (polysorbate-60).

Skin stickiness of tattoo stickers is due to the role of gelatin, which is one of the raw materials for tattoos. Gelatin is usually present as a solid (gel), but when water is present at a certain temperature or more, the gelatin is dissolved into a solution (sol). At this time, the adhesion can be easily made with other materials.

In light of this, the present inventors used a cactus extract having a decomposing effect of gelatin as a means for decomposing and removing dyes and gelatin, which are main components of tattoo stickers.

In the present invention, the cactus and plant extract mixture is characterized in that aloe extract, agave extract, baeknyeoncho extract is dissolved in ethanol.

In the present invention, the cactus plant extract was prepared by dissolving aloe extract, agave extract, and baeknyeoncho extract in ethanol at a weight ratio of 1: 1: 1. After the tattoo sticker was attached to the skin, the effect of removing the tattoo sticker was tested. At this time, when the content of the cactus and the plant extract was less than 0.75% by weight, the sticker was not removed, and the redness of the skin (rash) caused by the irritation generated during the removal was not alleviated. When the cactus and plant extract mixtures exceeded 1.5% by weight, there was no difference in tattoo sticker removal.

In the present invention, ethanol acts as a solvent for diluting the cactus and plant extract mixture in purified water and also dissolves the tattoo sticker dye. In the tattoo sticker dye removal test, when the ethanol content ratio was less than 10% by weight, the dye of the tattoo sticker was not removed well, and there was no difference at more than 30% by weight.

In the present invention, polysorbate-60 is a solvent widely used as a surfactant-emulsifier in cosmetics and removes this substance from the skin, and when dissolved, it is dissolved in water and effectively removes it. Polysorbate-60 less than 0.05% by weight of the tattoo sticker is not easily removed when removed from the skin and irritating the skin, while when exceeding 0.15% by weight it is rather difficult to remove due to slipping.

According to a preferred embodiment of the present invention, the composition of the present invention may include the cactus and plant extract mixture, ethanol and polysorbate-60 in a weight ratio of 0.5 to 1.5: 10.0 to 30.0: 0.05 to 0.15 have. If it exceeds the above range, there is no difference in the removal effect, but rather adverse effects such as slipping upon removal.

Preferably, the cactus and plant extract mixture, ethanol and polysorbate-60 may be included in a weight ratio of 1.0: 20.0: 0.1.

Preferably, the cactus and plant extract mixture, ethanol and polysorbate-60 may be included in a weight ratio of 1.5: 20.0: 0.15.

More preferably, the cactus and plant extract mixture may include aloe extract, agave extract and baeknyeoncho extract in a weight ratio of 1: 1: 1.

According to another embodiment of the present invention, the composition may be formulated into one kind selected from the group consisting of skin, cream and tissue, and preferably, a formulation of cream or tissue.

According to another embodiment of the present invention, in the tattoo sticker removal composition of the present invention, in addition to the active ingredient may further include a pharmacologically acceptable additive. Additives other than the above-mentioned effective ingredient are not particularly limited and can be used without limitation those that are commonly used.

In the composition for tattoo sticker removal of the present invention, additives other than the active ingredient are emulsifiers, soap acids, solvents, binders, diluents, lubricants, stabilizers, flavors, water, thickeners, chelating agents, pigments, preservatives, coloring agents, preservatives. , Antibiotics, antioxidants, antifoams, antimicrobials, antidepressants, enzymes, plant or mineral oils, fats, fluorescents, fungicides, combustibles, moisturizers, fragrances, fragrance carriers, preservatives, proteins, silicones, solubilizers, sugars It may contain one or two or more pharmacologically acceptable excipients selected from the group consisting of derivatives, vitamins, plant extracts and waxes.

In addition, the composition may be formulated into one selected from the group consisting of skin, cream and tissue.

In addition, the composition may further comprise a pharmacologically acceptable excipient in addition to the active ingredient.

The tattoo sticker removal composition of the present invention will be said to have the beneficial effect that the tattoo sticker can be removed quickly without irritating the skin, unlike when not used.

Figure 1 shows the tattoo sticker removal process.

Hereinafter, preferred examples are provided to aid in understanding the present invention. However, the following Examples and Experimental Examples are provided only to more easily understand the present invention, and the contents of the present invention are not limited thereto.

In addition, the aloe extract, agave extract, and baeknyeoncho extract mentioned below are purchased from Coseed Biopharm Co., Ltd., and polysorbate-60 is purchased from ATEC.

<Examples 1 to 7>  Preparation of Cactus and Plant Extract Mixtures According to the Present Invention

Aloe extract, agave extract, baeknyeoncho extract powder in a beaker was mixed in the composition of Table 1, respectively, and the mixed extract powder was prepared by diluting in ethanol to 1% by weight relative to the total weight. Ethanol was 20% by weight based on the total weight, the rest was filled with distilled water.

Composition ratio of cactus and plant extracts according to the present invention Aloe extract Agave Extract Zinnia extract Comparative Example 1 0 0 0 Example 1 1.0 0 0 Example 2 0.5 0.5 0 Example 3 0.5 0 0.5 Example 4 0 1.0 0 Example 5 0 0.5 0.5 Example 6 0 0 1.0 Example 7 0.333 0.333 0.333

Experimental Example 1. Evaluation of tattoo sticker removal effect of cactus and extract mixture

In order to examine the effect of removing the tattoo sticker according to the mixing ratio of the cactus and the plant extract mixture according to the present invention, after the solution of Examples 1 to 7 was soaked in a nonwoven tissue, the tattoo sticker was previously attached. At this time, the time required for complete removal was measured, and the results are shown in Table 2. Comparative Example 1 contained no cactus and plant extracts, ethanol was 20% by weight.

Time required for tattoo sticker removal and skin irritation of cactus Sample name Tattoo sticker removal time (min) Skin irritation degree Comparative Example 1 NR 8.97 ± 0.16 ^F Example 1 25.32 ± 2.53 ^D 9.02 ± 0.35 ^F Example 2 10.37 ± 1.21 ^C 3.24 ± 0.27 ^B Example 3 12.74 ± 0.93 ^C 7.16 ± 0.45 ^DE Example 4 7.54 ± 0.59 ^B 4.08 ± 0.18 ^C Example 5 5.68 ± 0.68 ^AB 5.96 ± 0.66 ^D Example 6 21.69 ± 3.18 ^D 8.05 ± 0.29 ^E Example 7 3.12 ± 0.46 ^A 1.95 ± 0.43 ^A

(N = 20)

NR: The tattoo sticker is not removed and remains on the skin.

A-F: The other letters among the shoulder letters of the results obtained for each concentration indicate statistical significance according to the concentration per evaluation item (p <0.05).

The tattoo sticker removal effect of the composite prepared with aloe extract, agave extract, and baeknyeoncho extract, 20% by weight ethanol solution alone or two or more mixtures are shown in Table 2 above.

When aloe extract and baeknyeoncho extract were used alone, it took 25.32 minutes (Example 1) and 21.69 minutes (Example 6) to completely remove them. However, when agave extract was used alone, It took 7.54 minutes (Example 4).

In the two mixed solutions, the aloe extract and the agave extract were mixed 10.37 minutes (Example 2), the aloe extract and zinnia extract mixture was 12.74 minutes (Example 3), the agave extract and zinnia extract mixture was 5.68 minutes (Example 5) Agave extract and zinnia extract were found to be the most effective.

When the aloe extract, agave extract, baeknyeoncho extract was prepared by mixing the same ratio to measure the removal effect, it was 3.12 minutes (Example 7) showed the best removal effect.

When the degree of skin irritation felt by the subject was measured, the degree of irritation was severely proportional to the time required for tattoo sticker removal. Treatment with aloe extract alone showed the same skin irritation as the control without extract (Comparative Example 1).

<Examples 8 to 10> Preparation of the cactus and plant extracts and alcohol composite composition according to the present invention

Experimental Example 1 Aloe extract, agave extract, baeknyeoncho extract powder prepared in the composition of Example 7 was the best removal effect of the tattoo sticker in a beaker after mixing the type of alcohol as shown in Table 3 below methanol, ethanol, methanol And a mixture of ethanol and 1: 1 mixed alcohol solution to 20% by weight of the total weight, cactus and plant mixed extract to 1% by weight of the total weight, the remainder was filled with distilled water to prepare a mixture solution.

Types of alcohol included in the composition according to the invention Composition ratio of cactus and plant extracts Alcohol types Comparative Example 2 Aloe Vera Extract: Agave Extract: Perennial Extract = 1: 1: 1 - Example 8 Methanol Example 9 ethanol Example 10 Methanol + Ethanol (1: 1)

Experimental Example 2. Evaluation of tattoo sticker removal effect according to alcohol type

7.0 mL of the solution prepared in the configuration of Examples 8 to 10 was soaked in a nonwoven tissue, and then, the previously attached tattoo sticker was removed. At this time, the time required for complete removal was measured, and the results are shown in Table 4. In Comparative Example 2, purified water was used instead of alcohol.

Effects of tattoo sticker removal and skin irritation test by alcohol type Sample name Tattoo sticker removal time (min) Skin irritation degree Comparative Example 2 12.46 ± 1.43 ^C 7.02 ± 0.31 ^C Example 8 5.12 ± 0.76 ^B 2.97 ± 0.43 ^B Example 9 3.09 ± 0.38 ^A 1.87 ± 0.54 ^A Example 10 5.08 ± 0.65 ^B 3.07 ± 0.25 ^B

(N = 20)

A-F: The other letters among the shoulder letters of the results obtained for each concentration indicate statistical significance according to the concentration per evaluation item (p <0.05).

The effect of tattoo sticker removal of the mixture according to 20% by weight of 20% by weight of ethanol, 20% by weight of methanol, and 1: 1 by weight of methanol and ethanol by mixing three kinds of cactus and three plant-derived extracts Indicated. When the solution dissolved in purified water instead of ethanol was used as a control (Comparative Example 2), the control took 12.46 minutes of tattoo sticker removal, while 20 wt% methanol (Example 8) was 5.12 minutes and 20 wt% ethanol (Example 9) took 3.09 minutes and 20 wt% mixed alcohol (Example 10) took 5.08 minutes, showing the fastest removal time when dissolved in 20 wt% ethanol. The skin irritation degree was the least irritated with 20% by weight ethanol treatment was 1.87, 20% by weight methanol and 20% by weight mixed alcohol treatment showed similar skin irritation.

<Example 11-13> A composite composition comprising a cactus and plant extract, an alcohol, and a surfactant according to the present invention

Polysorbate-60, glyceryl stearate, and PIG-100 stearate were used in the composition of Example 9, which had the highest effect of removing tattoo stickers in Experimental Example 2. 0.1 wt% of each was added to prepare as shown in Table 5 to prepare a composite composition.

Type of surfactant included in tattoo sticker remover according to the present invention Cactus and Plant Extract Mixture and Alcohol Composition Surfactants Comparative Example 3
Same as the composition of Example 9 - Example 11 Glyceryl Stearate Example 12 Fiji-100 Stearate Example 13 Polysorbate-60

Experimental Example 3. Evaluation of Tattoo Sticker Removal Effect by Surfactant Type

7.0 mL of the solution prepared in the configuration of Examples 11 to 13 was soaked in a nonwoven tissue and then used for a tatoo sticker removal test attached in advance. At this time, the time required for complete removal and the degree of skin irritation were measured, and the results are shown in Table 6. In Comparative Example 3, no surfactant was added.

Tattoo sticker removal and skin irritation test results according to surfactant type Sample name Tattoo sticker removal time (min) Skin irritation degree Comparative Example 3 3.17 ± 0.23 ^C 3.08 ± 0.33 ^D Example 11 3.06 ± 0.16 ^C 2.24 ± 0.19 ^C Example 12 2.28 ± 0.31 ^B 1.86 ± 0.62 ^B Example 13 1.45 ± 0.38 ^A 0.85 ± 0.64 ^A

(N = 20)

A-D: The other letters among the shoulder letters of the results obtained for each concentration indicate statistical significance according to the concentration per evaluation item (p <0.05).

 Control Example 3 took the tattoo sticker removal time 3.17 minutes, while glyceryl stearate (Example 11) was 3.06 minutes, PIG-100 stearate (Example 12) was 2.28 minutes, polysorbate-60 Silver (Example 13) was found to be 1.45 minutes, the effect of polysorbate-60 was the highest, and the degree of skin irritation also showed a tendency to be lowered proportionally to the time between removals.

Examples 14 to 19 Preparation of Mixed Composition According to the Present Invention

To prepare a mixed composition of Examples 14 to 19 according to the mixing ratio of Table 7. Cactus and plant extract mixture was used in a mixture of aloe extract, agave extract, and baeknyeoncho extract in a ratio of 1: 1: 1, 0.5, 1.0, 1.5% by weight, ethanol 10% by weight or It was prepared to 20% by weight, and polysorbate-60 was added at the time of composition preparation to be 0.05%, 0.1, 0.15% by weight of the final composition.

Composition of tattoo sticker remover mixture according to the present invention ingredient Comparative Example 4 Example 14 Example 15 Example 16 Example 17 Example 18 Example 19 Cactus Extract Mixture - 0.5 0.5 1.0 1.0 1.5 1.5 Ethanol solution - 10.0 20.0 10.0 20.0 10.0 20.0 Polysorbate-60 - 0.05 0.05 0.1 0.1 0.15 0.15 Tertiary distilled water
(Or purified water) 100 89.45 79.45 88.90 78.90 88.35 78.35 Sum 100 100 100 100 100 100 100

Experimental Example 4: Evaluation of tattoo sticker removal effect of the mixed composition according to the present invention

In order to evaluate the effect of tattoo sticker removal of the mixed composition of Comparative Example 4 and Examples 14 to 19, a trial evaluation group consisting of 20 people was subjected to tattoo sticker removal and skin irritation test. 7.0 mL of the solution prepared in the configuration of Examples 14 to 19 was soaked in a nonwoven tissue and used for a tatoo sticker removal test attached in advance. Comparative Example 4 was compared by simple distilled water treatment as a control.

First, the tattoo sticker was adhered to the right arm upper arm according to the conventional method, and then dried for 20 minutes. The mixed tattoo sticker was removed using a nonwoven tissue absorbed by 7.0 mL of the mixed composition of Comparative Example 4 and Example. At this time, the time taken for removal was measured. The skin irritation test was performed by distinguishing the degree of irritation to the attached skin during removal by the subject on a 9-point scale. The stimulus was very high at 1 point that there was no stimulus was made into 9 points. Table 8 shows the results of the time taken for the tattoo sticker removal and the degree of skin irritation.

Tattoo sticker removal and skin irritation test results according to mixed composition Sample name Tattoo sticker removal time (min) Skin irritation degree Comparative Example 4 NR 8.85 ± 0.42 ^C Example 14 5.32 ± 0.35 ^C 2.78 ± 0.33 ^B Example 15 4.67 ± 0.33 ^C 2.54 ± 0.41 ^B Example 16 3.09 ± 0.26 ^B 2.09 ± 0.46 ^A Example 17 1.21 ± 0.36 ^A 1.02 ± 0.31 ^A Example 18 1.47 ± 0.45 ^A 0.92 ± 0.35 ^A Example 19 1.25 ± 0.32 ^A 0.87 ± 0.46 ^A

(N = 20)

NR: The tattoo sticker is not removed and remains on the skin.

A-C: The other letters among the shoulder letters of the results obtained for each concentration indicate statistical significance according to the concentration per evaluation item (p <0.05).

The composite composition for tattoo sticker removal is a mixture of aloe extract, agave extract, and baeknyeoncho extract in the same mixing ratio of 1: 1 1: 1.0% by weight, 20% by weight of ethanol and 0.1% by weight of polysorbate- In Example 17, the treatment containing 60, the removal effect was the highest, and it took less than 1.5 minutes to completely remove it. The degree of skin irritation was also low in these mixed composition treatments, indicating a significant correlation with removal time. However, the effects in Examples 17-19 were not statistically significant.

It is believed that the effect of the composite composition of aloe extract, agave extract, white lotus flower extract, ethanol and polysorbate-60 of the present invention, which can minimize and quickly remove the tattoo sticker from the skin, is excellent.

Claims (7)

A mixture of cactus and plant extracts, including aloe extract, agave extract, baeknyeoncho extract, ethanol and polysorbate-60, a composition for removing tattoo sticker. The composition of claim 1, wherein the cactus and plant extract mixture, ethanol, and polysorbate-60 are included in a weight ratio of 0.5 to 1.5: 10.0 to 30.0: 0.05 to 0.15. The method of claim 1, wherein the cactus and (trophy) plant extract mixture is a tatoo sticker removal composition comprising aloe extract, agave extract, baeknyeoncho extract in a weight ratio of 1: 1. The composition of claim 1, wherein the ethanol is 20% by weight of the total composition. The composition of claim 1, wherein the cactus and plant extract mixture, ethanol, and polysorbate-60 are included in a weight ratio of 1.0 to 1.5: 10.0 to 20.0: 0.1 to 0.15. The composition for removing a tattoo sticker according to any one of claims 1 to 5, wherein the composition is formulated into one selected from the group consisting of skin, cream and tissue. The composition for tattoo sticker removal according to any one of claims 1 to 5, further comprising a pharmacologically acceptable excipient in addition to the active ingredient.

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