KR102069395B1 - 제i형 및 제ii형 당뇨병의 치료 - Google Patents

제i형 및 제ii형 당뇨병의 치료 Download PDF

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KR102069395B1
KR102069395B1 KR1020147019062A KR20147019062A KR102069395B1 KR 102069395 B1 KR102069395 B1 KR 102069395B1 KR 1020147019062 A KR1020147019062 A KR 1020147019062A KR 20147019062 A KR20147019062 A KR 20147019062A KR 102069395 B1 KR102069395 B1 KR 102069395B1
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insulin
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compounds
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Korean (ko)
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KR20140107416A (ko
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앤드류 지. 레움
마이클 에스. 사포리토
알렉산더 알. 오치만
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멜리어 파마슈티칼스 아이, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020147019062A 2011-12-12 2012-12-12 제i형 및 제ii형 당뇨병의 치료 Active KR102069395B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161569496P 2011-12-12 2011-12-12
US61/569,496 2011-12-12
PCT/US2012/069072 WO2013090319A2 (en) 2011-12-12 2012-12-12 Treatment of type i and type ii diabetes

Publications (2)

Publication Number Publication Date
KR20140107416A KR20140107416A (ko) 2014-09-04
KR102069395B1 true KR102069395B1 (ko) 2020-01-22

Family

ID=48613352

Family Applications (1)

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KR1020147019062A Active KR102069395B1 (ko) 2011-12-12 2012-12-12 제i형 및 제ii형 당뇨병의 치료

Country Status (14)

Country Link
US (2) US20150190396A1 (cg-RX-API-DMAC7.html)
EP (1) EP2790704B1 (cg-RX-API-DMAC7.html)
JP (1) JP6152387B2 (cg-RX-API-DMAC7.html)
KR (1) KR102069395B1 (cg-RX-API-DMAC7.html)
CN (2) CN107007608B (cg-RX-API-DMAC7.html)
AU (2) AU2012352480A1 (cg-RX-API-DMAC7.html)
BR (1) BR112014014289A2 (cg-RX-API-DMAC7.html)
CA (1) CA2859156C (cg-RX-API-DMAC7.html)
IL (1) IL233004B (cg-RX-API-DMAC7.html)
MX (1) MX359171B (cg-RX-API-DMAC7.html)
RU (1) RU2646475C2 (cg-RX-API-DMAC7.html)
SG (2) SG11201403207WA (cg-RX-API-DMAC7.html)
WO (1) WO2013090319A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201404738B (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10863264B2 (en) 2017-01-23 2020-12-08 David Sampson Vibration inducing tactile apparatus
WO2019139185A1 (en) * 2018-01-11 2019-07-18 Bukwang Pharmaceutical Co., Ltd. Method for preparing tolimidone on large scale

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070093516A1 (en) 2005-08-22 2007-04-26 Andrew Reaume Methods and formulations for modulating lyn kinase activity and treating related disorders
WO2011150300A1 (en) * 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3922345A (en) 1971-10-29 1975-11-25 Pfizer Pyrimidinones and hydroxy pyrimidines
SE9203753D0 (sv) 1992-12-11 1992-12-11 Kabi Pharmacia Ab Expression system for producing apolipoprotein ai-m
SE9500778D0 (sv) 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
US6004925A (en) 1997-09-29 1999-12-21 J. L. Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6037323A (en) 1997-09-29 2000-03-14 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
US7985422B2 (en) * 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
US20070025953A1 (en) * 2005-07-27 2007-02-01 Jones Michael R Co-therapy for diabetic conditions
RU2316339C1 (ru) * 2006-09-13 2008-02-10 Общество С Ограниченной Ответственностью "Концерн О3" Способ получения препарата инсулина для перорального применения
EP2120581A4 (en) * 2007-02-20 2011-03-16 Melior Pharmaceuticals I Inc METHODS OF IDENTIFYING LYN KINASE ACTIVATORS
EP2180894A4 (en) * 2007-07-23 2012-08-29 Melior Pharmaceuticals I Inc METHOD OF ACTIVATING IRS-1 AND ACT
ES2530223T3 (es) * 2008-12-12 2015-02-27 Poxel S.A.S. Combinación de insulina con derivados de triazina y su uso para tratar la diabetes
EP3609500B1 (en) * 2017-04-10 2024-11-13 Melior Pharmaceuticals I, Inc. Treatment of adipocytes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070093516A1 (en) 2005-08-22 2007-04-26 Andrew Reaume Methods and formulations for modulating lyn kinase activity and treating related disorders
US20100278804A1 (en) 2005-08-22 2010-11-04 Melior Pharmaceuticals I, Inc. Methods And Formulations For Modulating Lyn Kinase Activity And Treating Related Disorders
WO2011150300A1 (en) * 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration

Also Published As

Publication number Publication date
AU2012352480A1 (en) 2014-07-17
RU2014128528A (ru) 2016-02-10
IL233004B (en) 2020-01-30
MX2014006990A (es) 2015-02-05
ZA201404738B (en) 2016-10-26
HK1202819A1 (en) 2015-10-09
WO2013090319A2 (en) 2013-06-20
CN104271140B (zh) 2016-11-23
CN107007608B (zh) 2021-04-23
CN107007608A (zh) 2017-08-04
EP2790704B1 (en) 2019-04-03
BR112014014289A8 (pt) 2017-06-13
EP2790704A2 (en) 2014-10-22
AU2017204652B2 (en) 2018-08-16
BR112014014289A2 (pt) 2017-06-13
IL233004A0 (en) 2014-07-31
RU2646475C2 (ru) 2018-03-05
NZ626495A (en) 2016-03-31
US20200215068A1 (en) 2020-07-09
WO2013090319A3 (en) 2014-12-04
JP6152387B2 (ja) 2017-06-21
CN104271140A (zh) 2015-01-07
JP2015513310A (ja) 2015-05-07
SG10201604828QA (en) 2016-07-28
CA2859156C (en) 2020-10-06
AU2017204652A1 (en) 2017-07-27
EP2790704A4 (en) 2015-09-02
SG11201403207WA (en) 2014-09-26
CA2859156A1 (en) 2013-06-20
US20150190396A1 (en) 2015-07-09
KR20140107416A (ko) 2014-09-04
MX359171B (es) 2018-09-18

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