KR102034492B1 - Pet feed composition having enhanced immunity effect comprising extract mixture of edible insect, Acer tegmentosum, jujube and Hovenia dulcis as effective component - Google Patents

Abstract

The present invention relates to a feed composition for companion animals having an enhanced immunity effect containing a mixed extract of edible insects, Acer tegmentosum, jujube, and Hovenia dulcis as an active component. The mixed extract of edible insects, Acer tegmentosum, jujube, and Hovenia dulcis manufactured at a specific mixing ratio has an excellent effect of enhancing immunity of companion animals, thereby being able to be very usefully used in related industrial fields.

Description

Pet feed composition having enhanced immunity effect comprising extract mixture of edible insect, Acer tegmentosum, jujube and Hovenia dulcis as effective component}

The present invention relates to a feed composition for pets having an immunity enhancing effect containing a mixed extract of edible insects, bees, jujube and bark as an active ingredient.

While pets grow up as part of a family, they are frequently exposed to contaminated natural environments, processed foods, and stress, such as air and water pollution that humans experience. For this reason, various diseases such as skin diseases, respiratory diseases, and digestive disorders, which are common in humans, are also developed in pets. In addition, since dogs live in indoor spaces, they are less likely to be obese due to lack of exercise, and the possibility of secondary disease is high. Therefore, medicines and feeds using natural products for pets can increase their immunity and lead a healthy life. Material excavation is a very important task. According to the Korea Rural Economic Institute in October 2018, the domestic pet food market is estimated at 890 billion won, and the industry is estimated to reach 1 trillion won this year.

Edible insects are foods that contain high amounts of protein and unsaturated fatty acids, which have high nutritional value, high essential amino acids, high mineral content such as iron and phosphorus, and high amounts of vitamins. Edible insects include brown larva larvae, twin crickets, rice locusts, white silkworm silkworms, silkworm pupa, white spotted larvae, and beetle larvae. Edible insects are produced as a circular dry product, but most of them are produced in powder form due to visual aversion. Recently, new products have been released for consumers to consume in various forms. Extracts can be used to eat beneficial ingredients of edible insects without disgust and maintain their unique taste and texture. In Korea, insects are not yet widely used as food ingredients, but due to problems such as lack of food in the future, efforts to utilize insects as food ingredients are expected to increase gradually. In fact, insects contain many useful nutrients and are expected to be widely used when developed as feed ingredients.

Acer tegmentosum Maxim. ) Is a plant belonging to the Maple family, also called mountain cheongsam or mountain elm. The leaves are broad and the young stems are light green, the stems are very soft and broken well, the bark is thick and the material is white and light. Since bee is not toxic, it is a medicine that has almost no side effects in any constitution. It is also used for the purpose of alcohol detoxification by restoring the liver temperature to normal and allowing water to be excreted well. In addition, detoxification, blue blood, lipolysis, diuretic, neurostable action, antidiabetic action is known.

Jujube ( Zizyphus jujuba ) is a deciduous deciduous tree belonging to the sea buckthorn family, and there are two species with different ecotypes, such as Chinese jujube and Indian jujube. It is widely cultivated. Jujube is an alkaline food rich in vitamin C and contains a large amount of minerals such as calcium, phosphorus, and iron, which are known to reduce heat, relieve constipation, and stop coughing. It is also effective in stiffening, anti-aging, and nerve relieving effects. Recently, intestinal harmful enzyme inhibitory effect and antioxidant effect have been revealed.

Hovenia dulcis is a broad-leaved large tree belonging to the buckthorn family, called sesame or sesame. It is known to improve the function of the liver and to release the poison accumulated in the liver. It is known to have a function of relieving hangover symptoms such as headache, dizziness, bad breath, and exhaustion.

Meanwhile, Korean Patent No. 1728777 discloses "Pet feed powder containing insect powder and a method of preparing the feed using the same", and Korean Patent No. 1623744 discloses "Feed composition of white spotted flower radish" Is disclosed. However, it has not been disclosed yet for a pet animal feed composition having an immunity enhancing effect containing the mixed extract of the edible insects, bee, jujube and bark of the present invention as an active ingredient.

The present invention is derived from the above requirements, in the present invention, when the mixed insects of edible insects, bees, jujube and hawthorn trees prepared at a specific mixing ratio and mixed with the general feed to edible insects, The present invention was completed by confirming that immunity enhancement effect was remarkable as compared with the case where the single extract of bee, jujube and bark tree and a mixed extract of two or more thereof were mixed with a general feed.

In order to solve the above problems, the present invention provides a feed composition for pets having an immunity-improving effect containing a mixed extract of edible insects, bees, jujube and bark as an active ingredient.

The pet food composition comprising a mixed extract of edible insects, bees, jujube and barn tree as an active ingredient prepared at a specific mixing ratio according to the present invention is excellent in improving the immunity of pets, pet food related industries It can be very useful in the field.

In order to achieve the object of the present invention, the present invention provides a feed composition for pets having an immunity-improving effect containing a mixed extract of edible insects, bees, jujube and bark as an active ingredient.

In the pet food composition of the present invention, the mixed extract is to extract by mixing each powder of the edible insects, jujube, bee and liana in a weight ratio of 1 to 10: 1 to 10: 1 to 10: 1 to 10 It may be, preferably to be extracted by mixing in a weight ratio of 1-7: 1-7: 1-7: 1-7, and more preferably 2.5-3.5: 0.5-1.5: 1.5-2.5: 0.5 ~ The extraction may be performed by mixing at a weight ratio of 1.5, and most preferably, the extraction may be performed by mixing at a weight ratio of 3: 1: 2: 1, but is not limited thereto.

In addition, the powder may be prepared using lyophilization or hot air drying, but is not limited thereto.

In addition, the extraction may be to use water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof as the extraction solvent, preferably may be a hot water extraction using water, but is not limited thereto.

In addition, the edible insect may be any one selected from the group consisting of brown goose, cricket, grasshopper, silkworm, white spotted radish and beetle, but is not limited thereto.

In addition, the pet may be a dog or a cat, but is not limited thereto.

On the other hand, the feed composition according to the present invention can improve the nutritional status by supplying various external natural nutrients to the companion animal, build up the initial immune system by strengthening the basic stamina, can improve the immunity by improving the immunity. Here, immunity enhancement means the ability to stimulate certain immune functions important to the health of a pet or to modulate other immune functions that may potentially be involved in immune disorders such as inflammation, allergies, and stabilization of the intestinal flora , Reduction of mortality, and both avoidance and inhibition of diseases and inflammation, such as bacterial and viral infections.

According to one embodiment of the present invention, as a result of feeding a companion animal containing a composition extract of the edible insects, bee, jujube and bark tree as an active ingredient, there is no side effect and to feed a general feed without any addition ; Or sole extracts of edible insects, bees, jujube and bark; Mixed extract of edible insects and jujube; Mixed extracts of edible insects, bee and holly; And it was confirmed that the immunity is strengthened compared to the pets fed the normal feed to which the mixed extract of jujube, bee and holly tree is added.

In addition, it can be mixed and fed with the conventional pet food for general companion pets are easy to eat and wide range of application.

The feed composition of the present invention can be produced in various forms such as dry feed, semi-wet (semimoist) feed, wet feed, etc. according to methods known in the art, for example, powders, granules, pills, pellets, jelly , Canned feed, biscuits, croquettes, nuggets, flakes, snacks and the like.

In addition, the feed composition of the present invention may include one or more carriers, excipients or diluents, examples of the carriers, excipients and diluents include, lactose, dextrose, sucrose, sorbitol, mannitol, xylitol, erythritol, maltitol Starch, acacia rubber, alginate, gelatin, calcium phosphate, calcium silicate, cellulose, methyl cellulose, polyvinylpyrrolidone, water, methylhydroxybenzoate, propylhydroxybenzoate, talc, magnesium stearate and mineral oil Can be.

In addition, fillers, anti-coagulants, lubricants, wetting agents, fragrances, emulsifiers and preservatives may be further included.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for explaining the present invention more specifically, it is obvious to those skilled in the art that the scope of the present invention is not limited by them.

Production Example  1 to 3. White spotted flower , Bee , Jujube and Barn  Mixed extract manufacturer

Three-year-old white spotted radish was obtained by feeding a mixture of 15% by weight jujube powder and 85% by weight of sawdust, and fasted for 3 days to remove fecal matter from the body. After removing the foreign matter on the epidermis by washing, hot air drying or lyophilization to prepare a white spotted flower radish powder. Jujube, bee and holly were also washed, dried and ground to powder. The prepared white spotted radish, jujube, bee and hawthorn powder were mixed at the mixing ratios disclosed in Table 1 below, and 50 parts by weight of the sample was added to 100 parts by weight of water, followed by hot water extraction at 90 ° C. for 24 hours. To prepare a mixed extract of edible insects, bees, jujube and bark of the present invention (Preparation Example 1, Preparation Example 2 and Preparation Example 3), which was hot-air dried or lyophilized to powder and then used in the following examples .

Mixing ratio of white spotted flower lumber, jujube, bee and liana (weight ratio) White spotted flower Jujube Bee Hut Preparation Example 1 One One One One Preparation Example 2 2 2 2 One Preparation Example 3 3 One 2 One Comparative Example 1 4 One - - Comparative Example 2 3 - One One Comparative Example 3 - 3 One One Comparative Example 4 One - - - Comparative Example 5 - One - - Comparative Example 6 - - One - Comparative Example 7 - - - One

Comparative example  One. White spotted flower  And extract preparation of jujube

Three-year-old white spotted radish was obtained by feeding a mixture of 15% by weight jujube powder and 85% by weight of sawdust, and fasted for 3 days to remove fecal matter from the body. After removing the foreign matter on the epidermis by washing, hot air drying or lyophilization to prepare a powder, the jujube was washed and then dried and pulverized to powder. The white spotted radish and jujube powder prepared above were mixed in a weight ratio of 4: 1, and added to water, followed by hot water extraction at 90 ° C. for 24 hours to prepare a white spotted radish and jujube mixed extract (Table 1). After hot powder drying or lyophilization to powder, it was used in the following examples.

Comparative example  2. White spotted flower , Bee  And Barn  Mixed extract manufacturer

Three-year-old white spotted radish was obtained by feeding a mixture of 15% by weight jujube powder and 85% by weight of sawdust, and fasted for 3 days to remove fecal matter from the body. After removing the foreign matter on the epidermis by washing, hot-air drying or lyophilization to prepare a powder, and after washing the bee and hut trees, dried and pulverized and powdered, white spotted flower radish, bee and hawthorn powder 3 After mixing in a weight ratio of 1: 1, added to water, and extracted with hot water at 90 ℃ for 24 hours to prepare a mixed extract of white spotted radish, bee and liana (Table 1), which is hot air drying or freeze-drying Powdered and used in the following examples.

Comparative example  3. Jujube, Bee  And Barn  Mixed extract manufacturer

After washing the jujube, bee and hawthorn powder, drying and pulverizing, powdering the jujube, bee and hawthorn powder in a weight ratio of 3: 1: 1, adding water to water, and then hot water at 90 ° C. for 24 hours. Extracted to prepare a mixed extract of jujube, bee and hawthorn (Table 1), which was hot-air dried or lyophilized to powder and then used in the following examples.

Comparative example  4. White spotted flower  Sole extract manufacturer

Three-year-old white spotted radish was obtained by feeding a mixture of 15% by weight jujube powder and 85% by weight of sawdust, and fasted for 3 days to remove fecal matter from the body. After removing the foreign matter on the epidermis by washing, hot air drying or lyophilization, the powder was put in water, and hot water was extracted at 90 ° C. for 24 hours to prepare white spotted flower radish alone extract (Table 1). Or lyophilized and powdered and used in the examples below.

Comparative example  5. Jujube Sole Extract Manufacturer

After washing the jujube, the powder prepared by drying and pulverizing was put into water, followed by hot water extraction at 90 ° C. for 24 hours to prepare a bee sole extract (Table 1), which was powdered by hot air drying or lyophilization. Used in the examples below.

Comparative example  6. Bee  Sole extract manufacturer

After washing the bee wood, the powder prepared by drying and pulverizing was put into water, followed by hot water extraction at 90 ° C. for 24 hours to prepare a bee wood alone extract (Table 1), which was powdered by hot air drying or lyophilization. Used in the examples below.

Comparative example  7. Hut  Sole extract manufacturer

After washing the walnut tree, dried and pulverized powder was added to the water, and then extracted with hot water for 24 hours at 90 ℃ to prepare a hut alone extract (Table 1), it was powdered by hot air drying or lyophilization Then used in the following examples.

Example  1. Edible insects, Bee , Jujube and Barn  Immunity Enhancement Effect of Mixed Extract

0.1 kg of the above-mentioned single extract powder and two or more mixed extract powders (see Table 1) were added and mixed with 1 kg of general dog food (home family 10 kg, Korea Feed Co., Ltd.) sold on the market and mixed to prepare a mixed feed. Its immunity enhancing effect was confirmed. Specifically, 10 dogs (species: Maltese) of 5 months of age (average weight 0.5-1Kg) were each set to 5 experimental groups (preparation examples 1 to 3) and comparative control (comparative examples 1 to 7), and the salary for 30 days. The water was allowed to drink freely. Negative control group was fed the dog food without addition. 30 days after feeding, blood was collected from the dogs of the experimental group, the control group and the negative control group, and ELASA was performed to determine the effect of enhancing immunity by measuring the concentration of IgG (immunoglobulin G), one of immunoglobulins. .

As a result, as shown in Table 2, in the case of the experimental group fed a feed containing the mixed extract powder of the edible insects, bee, jujube and hut of the present invention (Preparation Examples 1 to 3), edible insects, bee trees It was confirmed that the IgG concentration in the blood was significantly increased compared to the control group fed a feed containing a single extract powder of jujube and hawthorn and two or more mixed extract powder, in particular, compared to Preparation Examples 1 and 2 It was found that the mixed extract powders of edible insects, bees, jujube and larvae prepared at the mixing ratio of Preparation Example 3 have an excellent immune enhancing effect. Therefore, through the above results, it can be seen that the feed composition comprising the mixed extract powder of the edible insects, bee, jujube and bark of the present invention has an effect of enhancing immunity since it increases antibodies, especially IgG, in blood. there was.

Evaluation of the Immunostimulating Efficacy of the Mixed Extract of Edible Insects, Beetles, Jujube and Raspberries group extract IgG (mg / dl) Experimental group Preparation Example 1 1027 ± 141 Preparation Example 2 1096 ± 335 Preparation Example 3 1319 ± 711 Comparative control Comparative Example 1 895 ± 368 Comparative Example 2 841 ± 556 Comparative Example 3 815 ± 023 Comparative Example 4 802 ± 117 Comparative Example 5 732 ± 421 Comparative Example 6 716 ± 779 Comparative Example 7 694 ± 782 Negative control Does nothing 659 ± 498

Claims (6)

It is for pets that have immunity-improving effect by mixing white spotted radish, jujube, bee and liana in a weight ratio of 2.5-3.5: 0.5-1.5: 1.5-2.5: 0.5-1.5 as an active ingredient. Feed composition. delete delete delete The pet food composition of claim 1, wherein the pet is a dog or a cat. delete