KR101998029B1 - Mic-1 단백질에 특이적으로 결합하는 항체 및 이의 용도 - Google Patents

Mic-1 단백질에 특이적으로 결합하는 항체 및 이의 용도 Download PDF

Info

Publication number
KR101998029B1
KR101998029B1 KR1020180071654A KR20180071654A KR101998029B1 KR 101998029 B1 KR101998029 B1 KR 101998029B1 KR 1020180071654 A KR1020180071654 A KR 1020180071654A KR 20180071654 A KR20180071654 A KR 20180071654A KR 101998029 B1 KR101998029 B1 KR 101998029B1
Authority
KR
South Korea
Prior art keywords
cancer
antibody
mic
seq
light chain
Prior art date
Application number
KR1020180071654A
Other languages
English (en)
Korean (ko)
Other versions
KR20190001538A (ko
Inventor
이한수
이재섭
성하영
손원준
에프테 카룰 알람 수몬 엠디
Original Assignee
강원대학교산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 강원대학교산학협력단 filed Critical 강원대학교산학협력단
Publication of KR20190001538A publication Critical patent/KR20190001538A/ko
Application granted granted Critical
Publication of KR101998029B1 publication Critical patent/KR101998029B1/ko

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
KR1020180071654A 2017-06-26 2018-06-21 Mic-1 단백질에 특이적으로 결합하는 항체 및 이의 용도 KR101998029B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170080653 2017-06-26
KR20170080653 2017-06-26

Publications (2)

Publication Number Publication Date
KR20190001538A KR20190001538A (ko) 2019-01-04
KR101998029B1 true KR101998029B1 (ko) 2019-07-08

Family

ID=64741654

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020180071654A KR101998029B1 (ko) 2017-06-26 2018-06-21 Mic-1 단백질에 특이적으로 결합하는 항체 및 이의 용도

Country Status (2)

Country Link
KR (1) KR101998029B1 (fr)
WO (1) WO2019004550A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100679666B1 (ko) 2004-01-20 2007-02-07 한국생명공학연구원 인간 대식세포 억제 사이토카인-1 특이적 단일클론항체,이를 분비하는 하이브리도마 및 이를 포함하는 위암 진단키트
KR101346132B1 (ko) 2013-02-18 2013-12-31 강원대학교산학협력단 Mic-1의 혈관신생유도 기능을 억제하는 항 mic-1 단일클론항체 mbm-14
KR101346181B1 (ko) 2013-02-18 2014-01-03 강원대학교산학협력단 Mic-1의 혈관신생유도 기능을 억제하는 항 mic-1 단일클론항체 mbm-12

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5448338B2 (ja) * 2004-04-13 2014-03-19 セントビンセンツ ホスピタル シドニー リミテッド 食欲を調節する方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100679666B1 (ko) 2004-01-20 2007-02-07 한국생명공학연구원 인간 대식세포 억제 사이토카인-1 특이적 단일클론항체,이를 분비하는 하이브리도마 및 이를 포함하는 위암 진단키트
KR101346132B1 (ko) 2013-02-18 2013-12-31 강원대학교산학협력단 Mic-1의 혈관신생유도 기능을 억제하는 항 mic-1 단일클론항체 mbm-14
KR101346181B1 (ko) 2013-02-18 2014-01-03 강원대학교산학협력단 Mic-1의 혈관신생유도 기능을 억제하는 항 mic-1 단일클론항체 mbm-12

Also Published As

Publication number Publication date
KR20190001538A (ko) 2019-01-04
WO2019004550A1 (fr) 2019-01-03

Similar Documents

Publication Publication Date Title
KR102472087B1 (ko) 인간화된, 마우스 또는 키메라 항-cd47 단클론 항체
JP4620591B2 (ja) ヒトインスリン様成長因子に対する遺伝子組換え抗体
JP2022071071A (ja) ＥｒｂＢ－２およびＥｒｂＢ－３に結合する抗体
JP5788384B2 (ja) 形質転換増殖因子アルファに結合し、Ｒａｓ遺伝子変異癌に対して増殖抑制活性を有する抗体
IL232726B2 (en) Her3-specific binding molecules and their uses
KR102360967B1 (ko) 신규 항-네트린-1 항체
AU2016292980B2 (en) Antibodies that bind to Sortilin and inhibit the binding of progranulin
US20160237162A1 (en) Binding molecules specific for her3 and uses thereof
US20230235047A1 (en) Anti-claudin18.2 antibody and use thereof
US11912777B2 (en) Antibodies binding TNFR2 and uses thereof
EP3239177B1 (fr) Nouvel anticorps anti-egfrviii et composition le comprenant
KR101998029B1 (ko) Mic-1 단백질에 특이적으로 결합하는 항체 및 이의 용도
WO2014175160A1 (fr) Anticorps monoclonal fonctionnel dirigé contre le facteur de croissance de type facteur de croissance épidermique se liant à l'héparine
KR20200143297A (ko) 신규 cthrc1에 특이적 항체 및 이의 용도
KR101856904B1 (ko) Pauf 단백질에 특이적으로 결합하는 항체 및 이의 용도
JP5838427B2 (ja) ヘパリン結合上皮増殖因子様増殖因子に対する機能性モノクローナル抗体
KR20230112544A (ko) Tm4sf5 특이적 인간화 항체 및 그의 용도
KR20130135869A (ko) 항 단쇄 제4형 콜라겐 폴리펩타이드 항체 및 이를 포함하는 종양의 진단, 예방 또는 치료용 약제
CN116284394A (zh) 分离的抗原结合蛋白及其应用

Legal Events

Date Code Title Description
A201 Request for examination
A302 Request for accelerated examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant