KR101952078B1 - Food composition for controlling body weight - Google Patents

Abstract

The present invention relates to a food composition for weight gain, wherein the food composition comprising isolated soy protein, fructose fructose powder, casein sodium and multivitamins has the effect of increasing body weight and muscle mass without side effects, Can be useful for weight gain applications for adolescents and adults.

Description

FOOD COMPOSITION FOR CONTROLLING BODY WEIGHT [0002]

The present invention relates to a food composition for weight control comprising isolated soy protein, crystalline fructose powder, sodium caseinate and multivitamins.

Many modern people are threatened by obesity due to industrialization and changes in eating habits, but there are also many people who worry about underweight. People who are underweight have a weakened immune system and are susceptible to infectious diseases such as tuberculosis, hepatitis and cold, and increase the risk of anemia, osteoporosis, reproductive problems and malnutrition. Especially, low birth weight in childhood can cause growth disturbance, affects secondary puberty, and causes problems in bone maturity, which adversely affects key growth. In addition, since the mortality rate increases as the age increases, maintaining a normal weight corresponding to the physique is as important as the obesity problem.

To increase your weight, you should choose foods that contain calories and nutrients rather than high-calorie foods filled with sugar and saturated fats, and include foods that are full of protein such as lean meat, fish, egg whites, beans, tofu, and dairy products . Proteins are needed for bone health, immune system enhancement, and recovery from disease. However, since it takes a lot of time and effort for the general public to take these foods, and it is difficult to implement them, weight control foods are widely used.

Weight control foods are foods that contain nutrients such as vitamins or minerals and are used to control calories to replace some or all of the diet for those who need weight control. These weight control foods include weight loss foods and food supplements to help with weight gain. Weight gain supplements include protein supplements to increase muscle, protein and carbohydrate supplements to increase body weight and muscle together, and carbohydrate supplements to increase body weight.

However, these supplements may cause kidney disease in protein supplements due to the high percentage of specific nutrients, and side effects such as diarrhea, indigestion and abdominal distension may occur in carbohydrate supplements. Therefore, there is a need for a food for weight gain which is safe and easy to use while having few side effects.

The inventors of the present invention completed the present invention by confirming that a food composition containing isolated soybean protein has a weight gain effect while having few side effects.

One aspect of the present invention is to provide a food composition for weight gain comprising isolated soy protein, fructose fructose powder, casein sodium and multivitamins.

One aspect of the present invention provides a food composition for weight gain comprising isolated soy protein, crystalline fructose powder, sodium caseinate and multivitamins.

The term "soy protein isolate (ISP)" in the present invention refers to a protein obtained by extracting defatted soybean with water or a weakly alkaline solution and isoelectric precipitation of the protein in the extract at pH 4 to 5, and fat, carbohydrate and other Only about 90% of the protein is removed by removing impurities. Because soybean is the only complete source of protein for plants, it has a quality similar to that of animal protein sources such as meat, eggs, and milk. In the present invention, the isolated soybean protein serves as a protein source, which helps increase muscle mass and weight.

According to one embodiment of the present invention, the isolated soy protein is preferably contained in an amount of 20 to 70% by weight, and most preferably 30 to 60% by weight based on the total weight of the food composition.

The term 'crystalline fructose' in the present invention refers to crystallized fructose powder excluding glucose in the disaccharide sugar. Fructose fructose can feel a sweet taste even in a small amount compared with sugar and has a glycemic index (GI ) Is about 19 degrees, which is lower than 65 of sugar.

According to one embodiment of the present invention, the fructose is preferably contained in an amount of 5 to 30% by weight, and more preferably 10 to 20% by weight based on the total weight of the food composition.

The term " sodium caseinate " in the present invention refers to sodium bonded to enhance the water-solubility of casein which is insoluble in water when purified with purified milk protein. It is a substance that is generally classified as a chemical compound but has proven to be stable enough not to allow an acceptable daily intake.

According to one embodiment of the present invention, sodium casein is preferably contained in an amount of 5 to 20% by weight, and most preferably 7 to 15% by weight based on the total weight of the food composition.

The term " multivitamin " in the present invention means a vitamin and a minerals such as vitamin A and B which can be taken simultaneously for convenience of taking. Vitamins and minerals are used for health and growth of the body and normal metabolism Is a nutrient needed for.

According to one embodiment of the present invention, the multi-vitamin is preferably contained in an amount of 0.5 to 10% by weight, and more preferably 1 to 7% by weight, based on the total weight of the food composition.

According to one embodiment of the present invention, the food composition for weight gain may further comprise a cookie-flavored powder and a honey powder.

'Cookie fragrance powder' is a kind of synthetic flavoring substances. Since the original flavor and odor are almost eliminated during the manufacturing process, the fragrance is separately added. Since the natural flavor is expensive, the artificial synthetic flavoring agent . The cookie-flavored powder may be a mixture of dextrin, cookie flavor base, and gum arabic.

According to one embodiment of the present invention, the cookie-flavored powder is preferably contained in an amount of 1 to 10% by weight, and more preferably 2 to 7% by weight based on the total weight of the food composition.

In the present invention, the term 'honey powder' is a natural sweetener in which honey is lyophilized in the form of granules, which is convenient to carry and store. Honey contains a large amount of vitamin P, enhances the function of vitamin C to make collagen, strengthens capillaries, and has antibacterial action.

According to one embodiment of the present invention, the honey powder is preferably contained in an amount of 1 to 10% by weight, and more preferably 2 to 7% by weight, based on the total weight of the food composition.

According to one embodiment of the present invention, the food composition for weight gain may further comprise a cream-flavored powder or a cocoa powder.

Since the creamy flavor powder is a kind of synthetic flavoring agent, the synthetic flavoring agent containing the above-mentioned cookie flavor powder is a chemical compound, and therefore, the substances notified in the 'Standards and Specifications of Food Additives' notified by the Food and Drug Administration shall be used.

According to one embodiment of the present invention, the cream-flavored powder is preferably contained in an amount of 1 to 10% by weight, and more preferably 2 to 7% by weight, based on the total weight of the food composition.

Cocoa powder refers to powdered cocoa powder that has been peeled off the skin after frying the cocoa beans. The cocoa powder is rich in polyphenols, polyvonols and dietary fiber, which have excellent antioxidant activity.

According to one embodiment of the present invention, the cream-flavored powder is preferably contained in an amount of 5 to 20% by weight, and more preferably 7 to 15% by weight, based on the total weight of the food composition.

Another aspect of the present invention provides a functional food for weight gain or a special nutrition food comprising the food composition of the present invention.

The term " special nutritional food " in the present invention means a nutritional supplement for the purpose of providing a specific purpose requiring special nutrition management such as infant, sick person, elderly person or pregnant woman, Or food prepared by mixing food and nutrients for the purpose of supplementing nutrients that may be lacking in daily diet. Infant formulas, growth formulas, nutritional supplement foods, and food substitutes.

The food composition according to the present invention can be added directly to the functional food or can be used together with other food or food ingredients and suitably used according to a conventional method. The amount of the active ingredient to be mixed can be suitably determined according to its use purpose (for prevention or improvement). There is no particular limitation on the kind of the functional food. Examples of the food include dairy products including beverages, meat, sausage, bread, biscuits, rice cakes, chocolates, candies, snacks, confectionery, pizza, ramen noodles, gums, ice cream, soups, And a combination thereof, all of which contain functional foods in a conventional sense.

Among the functional foods of the present invention, the beverage is not particularly limited to the other components other than those containing the above-mentioned composition as an essential ingredient in the indicated ratio, and may contain various flavors or natural carbohydrates as additional ingredients such as ordinary beverages. Examples of the above-mentioned natural carbohydrates include monosaccharides such as glucose, fructose and the like; Disaccharides such as maltose, sucrose and the like; And polysaccharides, for example, conventional sugars such as dextrin, cyclodextrin and the like, and sugar alcohols such as xylitol, sorbitol and erythritol. Natural flavors (tau martin, stevia extracts (e.g., rebaudioside A, glycyrrhizin, etc.) and synthetic flavors (saccharin, aspartame, etc.) can be advantageously used as flavors other than those described above .

In addition to the above, the functional food and the special nutrition food of the present invention can be used as a nutritive, a vitamin, a mineral (electrolyte), a flavoring agent such as a synthetic flavor agent and a natural flavor agent, a colorant and an aggravating agent (cheese, chocolate etc.) Salts of alginic acid and its salts, organic acids, protective colloid thickening agents, pH adjusting agents, stabilizers, preservatives, glycerin, alcohols, carbonating agents used in carbonated drinks and the like. These ingredients may be used independently or in combination, and the proportion of such additives is not so critical, but is generally selected in the range of 0 to about 20 weight percent per 100 weight percent of the food composition of the present invention.

The food composition for weight gain comprising the isolated soybean protein, fructose fructose powder, casein sodium and multivitamins according to the present invention has the effect of preventing and improving low birth weight caused by nutritional imbalance without side effects, Can be useful for weight gain applications for adolescents and adults.

Fig. 1 is a graph showing the results of measurement of body weight of a mouse fed with cocoa or cookie nutrient shake.
FIG. 2 is a graph showing the results of comparing weight gain (%) in mice fed with cocoa or cookie nutrient shakes.
3 is a graph showing the results of comparing average daily gain (g) in mice fed with cocoa or cookie nutrient shakes.
FIG. 4 is a graph showing the results of comparing average daily intake (g) in mice fed with cocoa or cookie nutrient shakes.
FIG. 5 is a graph showing the results of a comparison of dietary efficiency in mice fed with cocoa or cookie nutrient shakes.
FIG. 6 is a graph showing the results of comparing the backfat thickness (%) in breeding mice fed with cocoa or cookie nutrient shakes.

Hereinafter, one or more embodiments will be described in more detail by way of examples. However, these embodiments are intended to illustrate one or more embodiments, and the scope of the present invention is not limited to these embodiments.

Manufacturing example  1: Food for weight gain (cocoa and cookies Nutritional shake )

Cocoa nutritional shake and cookie nutritional shake were prepared as follows.

160 g of crystalline fructose powder, 4 g of multi-vitamin, 4 g of honey powder, 4 g of cookie-flavored powder, 1 g of potassium chloride and 1 g of silicon dioxide were well mixed and homogenized by filtration through a 100-mesh sieve. Next, 46 g of isolated soybean protein, 12 g of casein sodium and 12 g of cocoa powder were added to the homogenized mixture, and the mixture was mixed for 60 minutes using a double cone mixer (JITECH, Korea) to prepare a cocoa nutritional shake.

A cook nourishing shake was prepared using the same method as the above cocoa nutritional shake.

The raw ingredients contained in the cocoa and cookie nutritional shake are listed in Tables 1 and 2, and each ingredient was purchased through AA Korea FPS (Seoul, Korea).

Experimental Example  1: Cocoa and Cookies Nutritional shake  Confirm ingestion efficacy

In order to confirm the effect of weight gain and biochemical change due to ingestion of cocoa or cookie nutritional shake, the following experiment was conducted.

2-1: Cocoa or cookies Nutritional shake  administration

A 6-week-old male ICR mouse (Orient Bio, Korea) was purchased and used for the experiment after one week in the laboratory. The breeding grounds were maintained at 12 hours light intensity, room temperature 22 degrees and humidity 60%. Feed water was used in general water supply, and feed and water supply were not restricted.

The control group was divided into three groups: control group (physiological saline group), experimental group 1 (cocoa nutritional shake group), and experimental group 2 (cookie nutritional shake group) The experimental group was orally administered powdered cocoa nutrition shake or cookie nutrition shake together with the solid feed at a concentration of 200 mg / kg / day daily for 15 days together with physiological saline. On the 15th day, solid feed was not supplied for fasting blood. The total length and body weight of the control and experimental mice were measured once a day and the amount of feed consumed by the animals was measured once a day for 15 days.

2-2: Confirmation of weight gain effect

The mice were weighed for a total of 16 times (0 and 7 to 21 days) during the 15-day sample administration period including the adaptation period (0 to 7 days).

As a result, as shown in the following Table 3 and FIG. 1, it was confirmed that the control group and the two experimental groups showed an increase in congestion, and the weight of the experimental group 2 to which the cookie nutritious shake was administered showed the greatest change.

As shown in FIG. 2, the body weight change was converted into weight increase rate according to the following equation (1). As a result, it was confirmed that weight gain was 6.17% in experimental group 1 and 8.64% in experimental group 2.

As shown in FIG. 3, the average daily gain (ADG) was 0.11 g, 0.14 g and 0.2 g in the control group, the experimental group 1 and the experimental group 2, respectively, 1 showed a 25% higher average daily gain and 75% higher in the experimental group 2.

As a result of confirming the average daily feed intake (ADFI) of the mice, it was confirmed that the control group was 5.42 ± 0.21 g, the experimental group 1 was 5.48 ± 0.11 g, and the experimental group 2 was 4.76 ± 0.23 g as shown in FIG. 4 .

As a result, the average daily intake was similar in the control group and the experimental group 1, and the average daily intake was lower in the experimental group 2 than in the control group and the experimental group 1.

Further, the dietary efficiency was calculated according to the following equation (2) using the daily average weight gain and average daily intake.

As a result, as shown in FIG. 5, the dietary efficiencies of the control group, the experimental group 1 and the experimental group 2 were 0.021, 0.026 and 0.042, respectively, which showed that the dietary efficiency was the highest in the experimental group 2. In the control group, Was 23.8% higher than that of the control group, and that of the experimental group 2 was about 100% higher than that of the experimental group 1, which was 61.9% higher than that of the experimental group 1.

1-2: Field measurement and electric field Growth rate  analysis

The overall length of the mouse was measured at the beginning and the end of the experiment to analyze the growth of the field.

As a result, as shown in Table 4, it was found that the maximum growth was observed in the experimental group 2 and 17.4% higher than that of the control group.

1-3: Fat and protein content analysis

After the end of the experiment, the mice were washed with distilled water and the thickness was measured to calculate the average value.

As a result, as shown in Fig. 6, the mean isthmus thickness of control group was 1.2 ± 0.19 ㎜, 1.32 ± 0.16 ㎜ in experimental group 1, and 1.32 ± 0.16 ㎜ in experimental group 2. As a result, it was confirmed that about 10% of the experimental group was thicker than that of the control group.

In addition, the concentration of muscle protein was measured and analyzed at the end of the experiment in mouse fusiform muscles. Specifically, after the blood collection, the thighs were removed from the mouse to disrupt the muscle tissue, and the tissues were dissolved by adding a buffer solution. Then, the proteins were quantified using BCA kit according to the manufacturer's instructions.

As a result, as shown in Table 5, it was confirmed that the muscle protein concentration of the fuzzy muscle of the experimental group 2 was about 3.68% higher than that of the control group.

1-4: Mouse serum biochemical analysis

The mice were fasted for 12 hours from the time point when the nutrition shake was completed, and then the mouse was inserted into the fixed frame without anesthesia, and then the fasting blood was collected from the tail. The collected blood was centrifuged at 4 ° C and 3,000 rpm for 15 minutes to separate the serum and stored at -70 ° C until the biochemical analysis. The concentrations of total cholesterol, high density lipoprotein (HDL), triglyceride, glucose and total protein in mouse serum were measured using a blood analyzer. The content of low density lipoprotein (LDL) and very low density lipoprotein (VLDL) was calculated by the Friedewald formula of the following equation (3).

The results of serum analysis are shown in Table 6 below.

Total cholesterol levels were slightly increased in the two experimental groups compared to the control group, but not significantly different. In the case of triglycerides, which were triglycerides, the total cholesterol level was increased in the two experimental groups as well as in the total cholesterol, .

In addition, high density lipoprotein-cholesterol (HDL-C) and low density lipoprotein-cholesterol (LDL-C) were found to increase the levels of high density lipoprotein-cholesterol in both groups compared with the control group. The values of the ultra-low density lipoprotein cholesterol (VLDL-C) also showed similar trends to the above results.

 In addition, glucose was reduced by 26.2% in the experimental group 1 and by 24.5% in the experimental group 2, compared with the control group.

The results of the above experiment show that when the cocoa nutrition shake or cookie nutrition shake is consumed, the weight of the experimental animal is increased, the electric field is grown, the level of high density lipoprotein cholesterol is increased and the normal range of blood glucose is maintained, .

The present invention has been described with reference to the preferred embodiments. It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims. Therefore, the disclosed embodiments should be considered in an illustrative rather than a restrictive sense. The scope of the present invention is defined by the appended claims rather than by the foregoing description, and all differences within the scope of equivalents thereof should be construed as being included in the present invention.

Claims (2)

In a food composition for weight gain,
The composition comprises 50% by weight of isolated soy protein, 18% by weight of crystalline fructose powder, 13% by weight of sodium caseinate, 4% by weight of multivitamin, 5% by weight of cookie flavor powder, 4% by weight of honey powder, 4% 1% by weight of silicon dioxide and 1% by weight of silicon dioxide,
Wherein the composition is a powder formulation for shaking,
The composition may comprise,
Preparing a homogenized mixture by mixing the fructose powder, the multivitamin, the honey powder, the cookie fragrance powder, the potassium chloride and the silicon dioxide, and then filtering and homogenizing the mixture with a 100 mesh mesh; And
Adding the separated soybean protein, sodium caseinate and cream fragrance powder to the homogenization mixture and mixing for 60 minutes
Lt; / RTI >
The composition is orally administered at a total dose of 200 mg / kg per day
Food composition for weight gain.
A functional food for weight gain comprising the food composition of claim 1.

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