KR101942197B9 - 세균 메타게놈 분석을 통한 전립선질환 진단 방법 - Google Patents

세균 메타게놈 분석을 통한 전립선질환 진단 방법

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Publication number
KR101942197B9
KR101942197B9 KR1020170180014A KR20170180014A KR101942197B9 KR 101942197 B9 KR101942197 B9 KR 101942197B9 KR 1020170180014 A KR1020170180014 A KR 1020170180014A KR 20170180014 A KR20170180014 A KR 20170180014A KR 101942197 B9 KR101942197 B9 KR 101942197B9
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KR
South Korea
Prior art keywords
diagnosis
analysis
prostate disease
metagenome
bacteria
Prior art date
Application number
KR1020170180014A
Other languages
English (en)
Other versions
KR101942197B1 (ko
KR20180077067A (ko
Inventor
김윤근
Original Assignee
주식회사 엠디헬스케어
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 주식회사 엠디헬스케어 filed Critical 주식회사 엠디헬스케어
Priority to PCT/KR2017/015576 priority Critical patent/WO2018124742A1/ko
Priority to US16/474,543 priority patent/US11708611B2/en
Priority to JP2019535312A priority patent/JP7084637B2/ja
Priority to CN201780081402.0A priority patent/CN110418848A/zh
Priority to EP17886869.1A priority patent/EP3564388B1/en
Publication of KR20180077067A publication Critical patent/KR20180077067A/ko
Application granted granted Critical
Publication of KR101942197B1 publication Critical patent/KR101942197B1/ko
Publication of KR101942197B9 publication Critical patent/KR101942197B9/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020170180014A 2016-12-28 2017-12-26 세균 메타게놈 분석을 통한 전립선질환 진단 방법 KR101942197B1 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PCT/KR2017/015576 WO2018124742A1 (ko) 2016-12-28 2017-12-27 세균 메타게놈 분석을 통한 전립선질환 진단 방법
US16/474,543 US11708611B2 (en) 2016-12-28 2017-12-27 Method for diagnosing prostatic disease via bacterial metagenomic analysis
JP2019535312A JP7084637B2 (ja) 2016-12-28 2017-12-27 細菌メタゲノム分析を通した前立腺疾患の診断方法
CN201780081402.0A CN110418848A (zh) 2016-12-28 2017-12-27 通过细菌宏基因组分析来诊断前列腺疾病的方法
EP17886869.1A EP3564388B1 (en) 2016-12-28 2017-12-27 Method for diagnosing prostatic disease via bacterial metagenomic analysis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020160181570 2016-12-28
KR20160181570 2016-12-28

Publications (3)

Publication Number Publication Date
KR20180077067A KR20180077067A (ko) 2018-07-06
KR101942197B1 KR101942197B1 (ko) 2019-01-24
KR101942197B9 true KR101942197B9 (ko) 2023-06-09

Family

ID=62921281

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020170180014A KR101942197B1 (ko) 2016-12-28 2017-12-26 세균 메타게놈 분석을 통한 전립선질환 진단 방법

Country Status (5)

Country Link
US (1) US11708611B2 (ko)
EP (1) EP3564388B1 (ko)
JP (1) JP7084637B2 (ko)
KR (1) KR101942197B1 (ko)
CN (1) CN110418848A (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019139279A1 (ko) * 2018-01-12 2019-07-18 주식회사 엠디헬스케어 모르가넬라 속 세균 유래 나노소포 및 이의 용도
KR102095355B1 (ko) * 2018-01-12 2020-03-31 주식회사 엠디헬스케어 모르가넬라 속 세균 유래 나노소포 및 이의 용도
WO2023021353A1 (en) * 2021-08-17 2023-02-23 Fondazione Per L’Istituto Oncologico Di Ricerca (Ior) Commensal bacteria promote endocrine-resistance in prostate cancer via androgen biosynthesis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2713909C (en) * 2008-02-01 2023-12-12 The General Hospital Corporation Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions
KR101128080B1 (ko) 2009-12-23 2012-03-29 한국생명공학연구원 메타게놈 라이브러리 유래 효소활성의 탐색 방법
EP2494865A4 (en) 2009-09-01 2014-05-14 Aeon Medix Inc EXTRACELLULAR VESICLES OBTAINED FROM THE DARMFLORA, AND METHOD FOR SEARCHING FOR A DISEASE MODEL, VACCINE AND CANDIDATE AND DIAGNOSTIC METHOD THEREFOR
WO2011027956A2 (ko) 2009-09-04 2011-03-10 주식회사이언메딕스 그람 양성 박테리아에서 유래한 세포밖 소포체 및 이를 이용한 질병 모델
GB201412834D0 (en) * 2014-07-18 2014-09-03 Cancer Rec Tech Ltd A method for detecting a genetic variant
BR112017011078B1 (pt) * 2014-11-28 2021-05-11 Anagenix Ip Limited usos de uma composição preparada a partir de kiwi ouro seco
KR101798176B1 (ko) 2014-12-16 2017-11-15 주식회사 엠디헬스케어 세균 유래의 나노소포체를 이용한 세균성 감염질환 원인균 동정방법
PL235777B1 (pl) * 2015-07-10 2020-10-19 Univ Jagiellonski Startery, sposób i zestaw diagnostyczny do diagnozowania sepsy
JPWO2017094805A1 (ja) * 2015-11-30 2018-09-13 株式会社Ｄｎａチップ研究所 ｃｔＤＮＡ量の測定による悪性新生物に対する治療の効果を評価する方法
KR102011375B1 (ko) * 2017-06-30 2019-08-16 주식회사 엠디헬스케어 프로테우스 속 세균 유래 나노소포 및 이의 용도
WO2019004668A1 (ko) 2017-06-30 2019-01-03 주식회사 엠디헬스케어 프로테우스 속 세균 유래 나노소포 및 이의 용도

Also Published As

Publication number Publication date
KR101942197B1 (ko) 2019-01-24
EP3564388A1 (en) 2019-11-06
KR20180077067A (ko) 2018-07-06
EP3564388A4 (en) 2020-09-02
JP2020503863A (ja) 2020-02-06
JP7084637B2 (ja) 2022-06-15
US20220259663A1 (en) 2022-08-18
CN110418848A (zh) 2019-11-05
US11708611B2 (en) 2023-07-25
EP3564388B1 (en) 2022-02-16

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