KR101898220B1 - 공초점 현미경 및 이를 이용한 영상 처리 방법 - Google Patents

공초점 현미경 및 이를 이용한 영상 처리 방법 Download PDF

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Publication number
KR101898220B1
KR101898220B1 KR1020150179848A KR20150179848A KR101898220B1 KR 101898220 B1 KR101898220 B1 KR 101898220B1 KR 1020150179848 A KR1020150179848 A KR 1020150179848A KR 20150179848 A KR20150179848 A KR 20150179848A KR 101898220 B1 KR101898220 B1 KR 101898220B1
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KR
South Korea
Prior art keywords
lens
unit
photographing
optical probe
image
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KR1020150179848A
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English (en)
Korean (ko)
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KR20170016773A (ko
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김필한
안진효
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한국과학기술원
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Priority to PCT/KR2016/010818 priority Critical patent/WO2017104949A1/fr
Publication of KR20170016773A publication Critical patent/KR20170016773A/ko
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Publication of KR101898220B1 publication Critical patent/KR101898220B1/ko

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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036Scanning details, e.g. scanning stages
    • G02B21/0048Scanning details, e.g. scanning stages scanning mirrors, e.g. rotating or galvanomirrors, MEMS mirrors
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008Details of detection or image processing, including general computer control

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Microscoopes, Condenser (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
KR1020150179848A 2015-08-04 2015-12-16 공초점 현미경 및 이를 이용한 영상 처리 방법 KR101898220B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/KR2016/010818 WO2017104949A1 (fr) 2015-08-04 2016-09-27 Microscope confocal et procédé de traitement d'images utilisant un tel microscope

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20150109841 2015-08-04
KR1020150109841 2015-08-04

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Publication Number Publication Date
KR20170016773A KR20170016773A (ko) 2017-02-14
KR101898220B1 true KR101898220B1 (ko) 2018-09-12

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KR1020150179848A KR101898220B1 (ko) 2015-08-04 2015-12-16 공초점 현미경 및 이를 이용한 영상 처리 방법

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KR (1) KR101898220B1 (fr)
WO (1) WO2017104949A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11300768B2 (en) 2020-02-05 2022-04-12 Samsung Display Co., Ltd. Optical inspection apparatus
KR20230059228A (ko) 2021-10-26 2023-05-03 포항공과대학교 산학협력단 목시플록사신을 이용한 생체조직표면 세포 영상검사장치 및 목시플록사신을 이용한 생체조직표면 세포 영상검사방법
KR102579826B1 (ko) * 2022-12-09 2023-09-18 (주) 브이픽스메디칼 인공지능 기반 진단 보조 정보 제공 방법, 장치 및 시스템
KR102643066B1 (ko) * 2022-12-09 2024-03-04 (주) 브이픽스메디칼 인공지능 기반 의사 컬러링을 활용한 진단 보조 정보 제공 방법, 장치 및 시스템

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102355866B1 (ko) * 2018-08-30 2022-01-25 성균관대학교산학협력단 초소형 내시경 프로브 및 이를 포함하는 다광자 내시경
KR102186327B1 (ko) * 2018-10-17 2020-12-03 한국과학기술원 생체 심부 조직의 미세 영상 획득 시스템 및 이의 미세 영상 제공 방법
CN109965987A (zh) * 2019-02-20 2019-07-05 广州乔铁医疗科技有限公司 一种具有共聚焦激光扫描功能的机器人外视镜
KR102258893B1 (ko) * 2019-11-28 2021-05-31 재단법인대구경북과학기술원 내시현미경의 수직 분해능 최적화 장치, 최적화 광학 시스템 및 최적화 방법

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004317437A (ja) * 2003-04-18 2004-11-11 Olympus Corp 光イメージング装置
JP2010503884A (ja) 2006-09-14 2010-02-04 パーキンエルマー・シンガポール・プライベート・リミテッド 走査型共焦点顕微鏡検査の改善、およびその関連技術
US20120184842A1 (en) 2009-09-17 2012-07-19 Mauna Kea Technologies Method, an optical probe and a confocal microscopy system for inspecting a solid organ
US20120268578A1 (en) 2009-08-26 2012-10-25 Tomophase Corporation Optical tissue imaging based on optical frequency domain imaging
JP5275804B2 (ja) * 2005-09-29 2013-08-28 ザ ジェネラル ホスピタル コーポレイション 1以上の生物学的構造体のマルチモダリティ顕微鏡画像生成を実行する装置及び方法
JP2014202550A (ja) * 2013-04-03 2014-10-27 オリンパス株式会社 複数の波長帯域に於ける単一発光粒子検出を用いた光分析装置及び光分析方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5552050B2 (ja) * 2008-06-27 2014-07-16 テルモ株式会社 留置針

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004317437A (ja) * 2003-04-18 2004-11-11 Olympus Corp 光イメージング装置
JP5275804B2 (ja) * 2005-09-29 2013-08-28 ザ ジェネラル ホスピタル コーポレイション 1以上の生物学的構造体のマルチモダリティ顕微鏡画像生成を実行する装置及び方法
JP2010503884A (ja) 2006-09-14 2010-02-04 パーキンエルマー・シンガポール・プライベート・リミテッド 走査型共焦点顕微鏡検査の改善、およびその関連技術
US20120268578A1 (en) 2009-08-26 2012-10-25 Tomophase Corporation Optical tissue imaging based on optical frequency domain imaging
US20120184842A1 (en) 2009-09-17 2012-07-19 Mauna Kea Technologies Method, an optical probe and a confocal microscopy system for inspecting a solid organ
JP2014202550A (ja) * 2013-04-03 2014-10-27 オリンパス株式会社 複数の波長帯域に於ける単一発光粒子検出を用いた光分析装置及び光分析方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11300768B2 (en) 2020-02-05 2022-04-12 Samsung Display Co., Ltd. Optical inspection apparatus
KR20230059228A (ko) 2021-10-26 2023-05-03 포항공과대학교 산학협력단 목시플록사신을 이용한 생체조직표면 세포 영상검사장치 및 목시플록사신을 이용한 생체조직표면 세포 영상검사방법
KR102579826B1 (ko) * 2022-12-09 2023-09-18 (주) 브이픽스메디칼 인공지능 기반 진단 보조 정보 제공 방법, 장치 및 시스템
KR102643066B1 (ko) * 2022-12-09 2024-03-04 (주) 브이픽스메디칼 인공지능 기반 의사 컬러링을 활용한 진단 보조 정보 제공 방법, 장치 및 시스템

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Publication number Publication date
KR20170016773A (ko) 2017-02-14
WO2017104949A1 (fr) 2017-06-22

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