KR101854252B1 - Cosmetic composition for preventing skin aging and improving skin elasticity comprising extract of orange peel as effective component - Google Patents

Abstract

The present invention relates to a cosmetic composition for preventing skin aging and improving elasticity containing an orange peel extract as an active ingredient. More specifically, 500 to 2000 parts by weight of water is added to 100 parts by weight of crushed orange peel, The present invention relates to a cosmetic composition for preventing skin aging and improving elasticity.
The cosmetic composition of the present invention exhibits excellent antioxidative activity and effectively inhibits fat accumulation of adipocytes, thereby providing excellent skin aging-preventing effect and skin elasticity-improving effect. In addition, the cosmetic composition of the present invention utilizes the orange peel to be disposed of, thereby further reducing the environmental pollution, and it is possible to contribute to the maintenance and development of the farm household by providing incidental income to the orange farming farm .

Description

TECHNICAL FIELD The present invention relates to a cosmetic composition for preventing skin aging and improving elasticity, comprising an orange peel extract as an active ingredient,

The present invention relates to a cosmetic composition for preventing skin aging and improving elasticity containing an orange peel extract as an active ingredient. More specifically, 500 to 2000 parts by weight of water is added to 100 parts by weight of crushed orange peel, The present invention relates to a cosmetic composition for preventing skin aging and improving elasticity.

Consumers are increasingly interested in beauty regardless of whether they are young or old, and cosmetics-related products are increasingly being sold. In the past, expensive imported brands and expensive cosmetics accounted for a large portion of the cosmetics market. Recently, however, the market has been segmented by focusing on safety and naturalism brands such as Skin Food, Innisfree and Nature Republic. In addition, DIY cosmetic products using natural products such as vegetables and fruits centered on individuals and small-scale groups are receiving favorable responses from consumers.

This is due to the increase in the number of people who want to enjoy a healthier life by improving the quality of life, and also because of the harmfulness problems of the products containing synthetic compounds recently emerging, they are interested in using natural substances in nature It is thought that it is because it increased. There are numerous natural substances in the natural world, and many of them have specific physiological activities. Therefore, if these natural substances can be used effectively, the possibility of harmfulness to the human body and the possibility of environmental pollution can be lowered have.

In this regard, the development of cosmetics using natural materials has been much attempted. For example, Korean Patent No. 10-1617152 discloses a cosmetic composition containing an extract obtained by processing the Rhus javanica undiladaceus extract in cosmetics to produce active oxygen scavenging effect, skin wrinkle improving effect, skin elasticity improving effect, photoaging prevention effect, Korean Patent No. 10-1550917 discloses a cosmetic composition for protecting skin, anti-aging, anti-wrinkle, elasticity improvement, whitening, moisturizing, and the like which contain ginseng seed oil or a phosphorus seed extract. And the like.

On the other hand, orange is used to produce food such as juice, jelly, jam, candy, etc. However, the orange peel produced as a byproduct after processing these foods is mostly disposed of as garbage. This orange peel has low bioavailability, despite the presence of a variety of physiologically active ingredients.

Therefore, the present inventor has tried to develop more useful product by utilizing the orange peel which has been disposed of mostly, and especially, in the production of beauty products, and tried to develop cosmetics which can satisfy the needs of modern consumers and can be used with confidence .

Korean Patent No. 10-1617152 Korean Patent No. 10-1550917

Accordingly, it is a main object of the present invention to provide a cosmetic composition which can be safely used by utilizing orange peel, which is a natural substance to be disposed of, and exhibits an excellent effect on cosmetics.

According to one aspect of the present invention, there is provided a method for producing an extract, which comprises adding 500 to 2000 parts by weight of water to 100 parts by weight of crushed orange peel, extracting the mixture at 110 to 130 캜 for 15 to 30 minutes, And a cosmetic composition for improving elasticity.

The cosmetic composition of the present invention has antioxidant activity and inhibits fat accumulation of adipocytes, thereby preventing skin aging and improving skin elasticity.

In the cosmetic composition of the present invention, the extract is preferably contained in an amount of 0.8 to 1.2% by weight based on the dry weight of the extract.

In the cosmetic composition according to the present invention, the extract is contained in an amount of 0.8 to 1.2% by weight based on the dry weight of the extract, 45 to 55% by weight of aloe gel, 5 to 8% by weight of tamarind oil, 2 to 5% % Of rosemary water and 2 to 5% by weight of rosemary water, and formulated into a mask pack filling formulation.

In the cosmetic composition of the present invention, the extract is contained in an amount of 0.8 to 1.2% by weight based on the dry weight of the extract, 70 to 75% by weight of aloe gel, 3 to 5% by weight of jojoba oil, , 7 to 9% by weight of hyaluronic acid, 3 to 5% by weight of palmitoyl oligopeptide and 1 to 3% by weight of napreotide, and is formulated into a water cream.

The cosmetic composition of the present invention exhibits excellent antioxidative activity and effectively inhibits fat accumulation of adipocytes, thereby providing excellent skin aging-preventing effect and skin elasticity-improving effect. In addition, the cosmetic composition of the present invention utilizes the orange peel to be disposed of, thereby further reducing the environmental pollution, and it is possible to contribute to the maintenance and development of the farm household by providing incidental income to the orange farming farm .

1 shows a process for preparing orange peel extract according to an embodiment of the present invention.
2 is a graph showing the DPPH radical scavenging activity of orange peel extract of the present invention.
FIG. 3 shows the results of analysis of the inhibitory activity on the adipocyte fat accumulation of the orange peel extract of the present invention, showing the results of oil red O staining.
FIG. 4 is a graph showing the results of analysis of the inhibitory activity on the adipocyte fat accumulation of orange peel extract of the present invention, which shows the fat accumulation rate measured by Oil Red O staining.
FIG. 5 shows the results of analysis of the inhibitory activity of the orange peel extract of the present invention on the adipocyte fat accumulation, which is a microscopic photograph of the fat accumulation of 3T3-L1 adipocytes.
6 shows a process of manufacturing a mask pack using orange peel extract according to an embodiment of the present invention.
FIG. 7 shows a process for producing a water cream using an orange peel extract according to an embodiment of the present invention.
8 is a graph showing a result of evaluating the satisfaction of the mask pack of the present invention through a survey.
9 is a graph showing a result of evaluating the satisfaction of the water cream of the present invention through a questionnaire.

The cosmetic composition of the present invention is characterized by containing an orange peel extract extracted under specific conditions as an active ingredient.

Even if it is a bark of the fruit belonging to the same citrus, it is necessary to distinguish it from the orange peel because it is different from the contained ingredient in the production of the extract. In addition, there is also a need to prepare an extract selectively using a skin for the effect expected in the present invention, in terms of utilizing a site that is not used in the production of food, .

In the present invention, 500-2000 parts by weight of water is added to 100 parts by weight of crushed orange peel using the orange peel as described above, followed by extraction at 110 to 130 ° C for 15 to 30 minutes. If the extraction conditions are such that the effects expected in the present invention can be sufficiently exhibited, the effect of improving the anti-aging and elasticity of the skin of the present invention may be significantly lowered.

The above extraction conditions can be easily achieved by using an autoclave.

Although the extract obtained through the extraction process can be used as it is in the cosmetic composition of the present invention, it is preferable to concentrate the active ingredient without losing or deteriorating the active ingredient after lyophilization, in order to more effectively prevent aging of skin and improve elasticity Do.

The cosmetic composition of the present invention may contain 0.1 to 90% by weight of the extract on the basis of the weight of the whole composition, but it is preferably 0.8 to 1.2% by weight for compatibility of the cosmetic composition and user preference. According to this, it can be stably dissolved or mixed with a solvent or excipient commonly used in cosmetics.

The cosmetic composition of the present invention can be used in cosmetics such as toners, lotions, creams, essences, lotions, milky lotions, packs, bags, foundation oils, lipsticks, And may be prepared into any of the formulations conventionally produced in the art.

For example, it can be formulated with solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansers, powder foundations, emulsion foundations, wax foundations, packs, massage creams and sprays But it is not limited thereto and can be manufactured in the form of a soft lotion, a nutritional lotion, a nutritional cream, a massage cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a spray or a powder have.

In particular, it is preferable that the orange peel extract of the present invention is formulated into a mask pack or a water cream to more effectively provide an effect of preventing skin aging and improving elasticity.

In the case of a mask pack formulation, for the stability of the formulation and for the effect on the skin, an orange peel extract is mixed with 0.8 to 1.2% by weight of an aloe gel 45 to 55% by weight, tamarind oil 5 to 8% by weight, jojoba oil 2 to 5% It is preferred that it is further prepared to contain 2 to 5% by weight of rosemary water.

The aloe gel is generally added to cosmetics as a skin conditioning agent, and the juice of the 'arboresscens' leaf is known to have an antibacterial action. The present invention neutralizes dry and oily skin and functions as a skin moisturizer. This material is mucilage obtained by squeezing the leaves of Aloe Barbadensis Miller or Aloe arborescens Miller and its variant (Liliaceae). It is a colorless, viscous, clear liquid with no odor.

The above-mentioned tamanu oil is a green oil component obtained by squeezing seeds of Calophylium inophyllum tree, which grows mainly in southwestern Asia, and contains a large amount of fatty acids such as oleic acid, linoleic acid, stearic acid and palmitic acid. In the present invention, tamanu oil can be added for the function of the skin moisturizing agent and the stable dissolution of the fat soluble component.

The jojoba oil is a colorless and odorless oil which is refined and the main ingredient is an unsaturated wax ester and rich in vitamin E. When used on skin, it does not shine, has good moisture retention, and has excellent absorbency. In the present invention, the jojoba oil can be added to improve the function of the skin moisturizing agent, the reduction of the shine of the skin and the absorption power.

The rosemary water is obtained by adding water to rosemary. Generally, the rosemary water is added to 500 g of rosemary at a ratio of 1 liter of water, and the mixture is steam distilled. Rosemary is a perennial herb that originates from the Mediterranean coast and has green leaves and distinctive scent. Rosemary is rich in rosmarinic acid, vitamin A, and vitamin C, so it has excellent antioxidant, antibacterial and bactericidal action. When used in cosmetics instead of distilled water, it prevents deterioration of cosmetics and removes odor and skin soothing effect of cosmetics.

In the case of a water cream formulation, it is preferable that, for the stability of the formulation and the effect on the skin, from 70 to 75% by weight of aloe gel, from 3 to 5% by weight of jojoba oil, from 1 to 3% by weight of propolis, It is preferable that it is prepared so as to further contain 7 to 9% by weight of lactic acid, 3 to 5% by weight of palmitoyl oligopeptide and 1 to 3% by weight of napreotide.

The propolis is generally added to cosmetics as a skin conditioning agent. It is a glue-like substance made by mixing bees with their saliva from components such as poplar, eucalyptus, pine, and buds and bark. It contains a mixture of yeast, wax, and bee's saliva, which are the active ingredients of many plants. Particularly, the flavonoid component contained in this raw material has anti-inflammatory and antimicrobial properties.

The hyaluronic acid is a biosynthetic natural substance which is present in a lot of skin, joints, tendons, ligaments, eyes, etc. in an animal such as an animal, and is involved in the moisturization of the skin and the lubrication of the joints. Also, because of its high viscosity, it acts to prevent damage to the skin from invasion of bacteria or physical and stimulation of the skin. Especially in the skin, it exists as a gel between collagen and elastin, which is a constituent of skin, to maintain skin moisture, prevent wrinkles and maintain skin elasticity.

The palmitoyl oligopeptide is preferably a palmitoyl tripeptide in the form of binding an oligopeptide to palmitic acid, more preferably a palmitoyl tripeptide, and more preferably palmitoyl tripeptide is a tripeptide of Gly-His-Lys (Pal-Gly-His-Lys) linked to the amino acid sequence of SEQ ID NO. Amino acids are mainly extracted from sugarcane and induce binding through chemical reaction. Since it was developed for the purpose of burn treatment, the effect of skin regeneration is excellent. It also has the effects of improving skin elasticity, reducing pores, improving pigmentation, and helping the skin's epidermal cell kinetics and the regeneration of the dermis. It can therefore be used for the recovery and elasticity of damaged or less elastic skin.

The naprei is a natural antimicrobial agent having a wide range of antimicrobial activity, and is widely used as natural functional cosmetics and natural preservative for foods. It is excellent in antimicrobial action against Gram bacteria due to amenonin component and tannin in root of Baekduhong. In the present invention, the free form can be used for the purpose of a natural preservative.

Hereinafter, the present invention will be described in more detail with reference to Examples. These embodiments are only for illustrating the present invention, and thus the scope of the present invention is not construed as being limited by these embodiments.

Example 1. Preparation of Orange Peel Extract

Orange, the main ingredient, was purchased at Lotte Mart Masan.

The oranges were washed and the shells were removed, cut, and dried in a dry oven. The dried orange peel was pulverized with a pulverizer, and then 800 ml of water was added to 80 g of the pulverized product. The pulverized product was put into an autoclave and heated at 121 ° C for 20 minutes for extraction.

The obtained extract was placed in a conical tube (50 ml) and centrifuged at 25 ° C and 2,500 rpm for 5 minutes to obtain an extract, which was filtered to obtain a filtrate. The filtrate was put into a freezer at -20 ° C and stored.

The filtrate stored in the freezer was thawed, transferred to a tray, placed in a -70 ° C deep freezer, frozen for 3 days, and lyophilized under reduced pressure for 4 days to obtain a lyophilized product (see FIG. The lyophilized product was used in the experiment while being stored in a -20 ° C freezer.

Experimental Example 1. Antioxidant activity measurement of orange peel extract

The antioxidant activity of the orange peel extract (lyophilized product) prepared in Example 1 was confirmed by a conventional DPPH assay to confirm the availability of the orange peel extract as a skin-beauty product.

DPPH radical scavenging is an antioxidant assay that measures the electron and hydrogen donating ability of antioxidants. 50 μl of orange peel extract was added to 1.95 ml of 200 μM DPPH solution in ethanol, and the mixture was reacted at room temperature for 30 minutes. The mixture was reacted at 490 ° C using a microplate reader (VersaMax; Molecular devices, Sunnyvale, Nm absorbance was measured. In the control group, 50 μl of dimethyl sulfoxide (DMSO) was added instead of the orange peel extract, and DPPH radical scavenging activity was calculated by the following method.

DPPH radical scavenging ability (%) = (1-A / B) x 100

A: Absorbance of orange peel extract treated group

B: Absorbance of the control group

As a result, as shown in FIG. 2, the orange peel extract showed a concentration-dependent inhibition of oxygen radicals. This means that the orange peel extract of the present invention has an excellent antioxidative activity and is effective in preventing aging of the skin due to such antioxidant activity.

Experimental Example 2. Measurement of inhibitory effect of orange peel extract on lipid accumulation

2-1. 3T3-L1 cell culture and adipocyte differentiation

3T3-L1 preadipocytes were used to determine lipid accumulation inhibitory activity of orange peel extracts. These cells are fibroblasts that differentiate into adipocytes by the treatment of adipocytes differentiation hormonal cocktail.

3T3-L1 preadipocytes were cultured in DMEM medium at 37 ° C, 5% CO ₂ until they were 100% confluent by adding 10% BCS and 1% penicillin-streptomycin. When 3T3-L1 preadipocytes were grown 100% in the cell culture dish, they were labeled Day -2. The day of induction of adipocyte differentiation using differentiation medium (DM) was denoted as Day 0, and the differentiation induction medium was DMEM medium supplemented with 10% FBS and 1% penicillin-streptomycin at a concentration of 500 μM IBMX, 5.2 (FBS) and 1% penicillin-streptomycin were added to the medium after post-differentiation medium (Post-DM) for 48 hours from Day 0 to Day 2, DMEM medium supplemented with only 167 nM insulin was used from Day 2 to Day 4. After addition of 10% FBS and 1% penicillin-streptomycin to DMEM medium, Day 4 to Day 7 were used, and adipocyte differentiation was terminated on Day 7.

2-2. Lipid accumulation inhibitory activity

To investigate the effect of orange peel extract on the adipogenesis process of 3T3-L1 cells, ORO (oil red O) staining method was used.

The orange peel extract (lyophilized product) prepared in Example 1 was treated for 3 days at Day 50, 100, 200, and 400 μg / Dyeing was performed on Day 7. The differentiated 3T3-L1 adipocytes were fixed with 3.7% (v / v) formaldehyde for 30 minutes at room temperature. Immobilized 3T3-L1 adipocytes were stained with 3 mg / ml ORO for 15 minutes at room temperature. OROs bound to lipids in adipocytes were dissolved in DMSO and transferred to a 96-well plate at a rate of 100 μl / well, and the absorbance was measured at 510 nm using a microplate reader. The percentage of fat accumulation (% of control) was calculated using Day 7's 3T3-L1 adipocytes not treated with the sample as a control. The effects of orange peel extract treatment on lipid fraction and size of 3T3-L1 adipocytes were also analyzed. The orange peel extract was treated in the same manner as above, and the lipid fraction and size of 3T3-L1 cells were observed on Day 7 through a microscope.

As a result, as shown in Figs. 3 to 5, the orange peel extract inhibited concentration constriction in 3T3-L1 adipocytes in a concentration-dependent manner.

The subcutaneous fat layer of human skin consists mainly of adipocytes. This subcutaneous fat layer protects the body by preventing heat damage and absorbing the impact. However, when excessive fat accumulates and the subcutaneous tissue thickens, the subcutaneous fat layer presses the blood vessel or the lymphatic vessel and circulation of blood and lymph is smooth And the cellulite phenomenon that causes the surface of the skin to become rugged like a mandarin orange peel is created.

Thus, the above results indicate that the orange peel extract of the present invention has an excellent effect of inhibiting fat accumulation of adipocytes, and can reduce the accumulation of subcutaneous fat such as cellulite on the basis of this effect. It is known that excessive formation of cellulite not only makes skin surface rugged but also presses blood vessels moving to dermis and epidermis to darken skin tone and promote the generation of black spot and freckle. Thus, prevention of excessive accumulation of subcutaneous fat means that it is effective in improving skin health.

Example 2 Preparation of mask pack using orange peel extract

A mask pack was prepared using the orange peel extract of Example 1 above.

Each material was mixed according to the contents of Table 1 to prepare a mask packed emulsion, and 35 ml of the emulsion prepared in a sealed packaging container containing one mask pack sheet was charged to prepare a mask pack (see FIG. 6).

Mask Pack Sample No. Sample 1 Sample 2 Sample 3 Aloe Soothing Gel 15 15 15 Aquatamanu oil 2 2 2 Jojoba oil One One One Rosemary water One One One Water (distilled water) 10.85 10.7 10.55 Orange peel extract 0.15 (0.5%) 0.3 (1%) 0.45 (1.5%) Sum 30 30 30

* Unit: g

Example 3. Preparation of water cream using orange peel extract

A water cream was prepared using the orange peel extract of Example 1 above.

Each material was mixed according to the contents of Table 2 to prepare a water cream, and 25 ml of the cream was prepared in a closed container to prepare a sample (see FIG. 7).

Moisture Cream Sample No. Sample 1 Sample 2 Sample 3 Aloe Soothing Gel 18 18 18 Jojoba oil One One One Propolis 0.5 0.5 0.5 Hyaluronic acid 2 2 2 Pal-GHK One One One Water (distilled water) 1.875 1.75 1.625 Free 0.5 0.5 0.5 Orange peel extract 0.125 (0.5%) 0.25 (1%) 0.375 (1.5%) Sum 25 25 25

* Unit: g

Experimental Example 3. Satisfaction Survey of Mask Pack and Moisture Cream

Each of the mask packs and moisture cream samples prepared in Examples 2 and 3 were subjected to 20-year college students (aged 19-24 years) for a total of 3 weeks. The subjects were selected as students who voluntarily agreed to explain the purpose, method, and contents of this study. Infectious diseases, atopic dermatitis, dermatitis within the last 3 months, and those currently undergoing skin treatment were excluded. A total of 20 subjects (10 mask packs, 10 cream creams) participated in the study. We instructed the researcher to report the abnormal skin symptoms that occurred during the use of the test product to the researcher immediately, informed the contact, and checked whether there was any abnormality every week. The mask pack was applied to the face part of the face once a week and to the subjects of the moisture cream twice a day in the morning and the evening both inside, outside and inside of the elbow. A questionnaire survey was conducted on satisfaction after the experiment compared with before the experiment. The questionnaires used in the questionnaire were as follows: (1), (2), (3), (4), and (5) .

As a result, as shown in FIGS. 8 and 9, the sample containing 1% of orange peel extract in both mask pack and water cream showed the best overall satisfaction in items such as moisturizing, sensitivity, palatability, and repurchase intention.

<Before the experiment>

1. Do you know your skin type well?

2. Do you usually think your skin is sensitive?

3. Do you usually think your skin is dry?

4. Do you often have trouble with your skin?

5. Does your skin have a high elasticity?

6. Do you often get horny on your skin?

7. Do you purchase according to cosmetic ingredients?

8. Do you buy according to the fragrance of cosmetics?

9. Do you purchase according to cosmetic container and design?

10. Have you ever felt a sense of warmth when using cosmetics?

11. Have you ever had trouble using cosmetics?

12. Have you ever felt any sense of emotion when using cosmetics?

13. Have you ever felt a pull when using cosmetics?

14. Are you interested in natural cosmetics?

15. Are you interested in cosmetics made from fruits?

16. Do you use mask packs often?

17. Do you often use water cream?

<Contents of questionnaire after experiment (mask pack)>

1. Are you satisfied with the product's fragrance?

2. Are you satisfied with the color of the product?

3. Are you satisfied with the size of the sheet?

4. Is the shape of the sheet suitable?

5. Are you satisfied with the material of the seat?

6. Do you have allergies to cosmetics made from fruits?

7. Do you have allergies to oranges?

8. Do you have an objection to the product made of orange peel?

9. Was the amount of sample mixture adequate?

10. Was the viscosity of the mixture in the sample proper?

11. Are you satisfied with the adhesion of the product?

12. Does the essence flow when using the product?

13. Are there any burns when using the product?

14. Do you think it was moisturizing after using the product?

15. Do you think there was oil after using the product?

16. After using the product, is the oil well mixed?

17. Did you feel warm after using the product?

18. Did you experience an allergic reaction after using the product?

19. Do you think the elasticity of the product has increased after use?

20. Do you think it is irritating after using the product?

21. Did you have excessive hairiness the next day?

22. Have you had skin soothing the following day?

23. Use of the product Do you think the make-up was good the next day?

24. Do you think that the recommended optimal pack time is appropriate?

25. Are you satisfied with the product used as a whole?

26. Are you willing to re-use the product?

27. Are you willing to recommend the product to others?

28. Other comments

<After the experiment Questionnaire contents (moisture cream)>

1. Are you satisfied with the product's fragrance?

2. Are you satisfied with the color of the product?

3. Are you satisfied with the design of the product?

4. Was the amount of mixture in the sample proper?

5. Was the viscosity of the mixture in the sample proper?

6. Do you have allergies to cosmetics made from fruits?

7. Do you have allergies to oranges?

8. Do you have an objection to the product made of orange peel?

9. Are you satisfied with the absorption of the product?

10. Are there any burns when using the product?

11. Do you think it was moisturizing after using the product?

12. Do you think there was oil after using the product?

13. After using the product, is the water well harmonized?

14. Did you feel warm after using the product?

15. Did you experience an allergic reaction after using the product?

16. Do you think the elasticity of the product has increased?

17. Do you think it is irritating after using the product?

18. Did you have excessive oiliness the next day?

19. Have you had skin soothing the following day?

20. Using the product Do you think the makeup was good the next day?

21. Do you think that the recommended optimal pack time is appropriate?

22. Are you satisfied with the product used as a whole?

23. Are you willing to reuse the product?

24. Are you willing to recommend the product to others?

25. Other comments

Claims (5)

500-2000 parts by weight of water is added to 100 parts by weight of crushed orange peel, and the mixture is extracted at 110 to 130 ° C for 15 to 30 minutes. The obtained extract is centrifuged to obtain an extract, which is then filtered and freeze- Extract as an active ingredient, 0.8 to 1.2% by weight, based on the dry weight of the orange peel extract;
45 to 55% by weight of an aloe gel;
5 to 8% by weight of tamarind oil;
2 to 5% by weight of jojoba oil; And
2 to 5% by weight of rosemary water;
The cosmetic composition for inhibiting fat accumulation and improving elasticity of adipocytes of the skin, which is formulated into a liquid for filling a mask pack. delete delete delete 500-2000 parts by weight of water is added to 100 parts by weight of crushed orange peel, and the mixture is extracted at 110 to 130 ° C for 15 to 30 minutes. The obtained extract is centrifuged to obtain an extract, which is then filtered and freeze- Extract as an active ingredient, 0.8 to 1.2% by weight, based on the dry weight of the orange peel extract;
70 to 75% by weight of an aloe gel;
3 to 5% by weight of jojoba oil;
1 to 3% by weight propolis;
7 to 9% by weight of hyaluronic acid;
3-5% by weight of a palmitoyl oligopeptide; And
1 to 3% by weight of nepheline,
Wherein the composition is formulated with a water cream.

Images