KR101822784B9 - 신경혈관단위-온-칩 및 그 칩의 제조방법 - Google Patents

신경혈관단위-온-칩 및 그 칩의 제조방법

Info

Publication number
KR101822784B9
KR101822784B9 KR20170012464A KR20170012464A KR101822784B9 KR 101822784 B9 KR101822784 B9 KR 101822784B9 KR 20170012464 A KR20170012464 A KR 20170012464A KR 20170012464 A KR20170012464 A KR 20170012464A KR 101822784 B9 KR101822784 B9 KR 101822784B9
Authority
KR
South Korea
Prior art keywords
unitnvu
neurovascular
fabricating
chip
same
Prior art date
Application number
KR20170012464A
Other languages
English (en)
Other versions
KR101822784B1 (ko
KR20170087837A (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to KR1020170012464A priority Critical patent/KR101822784B1/ko
Publication of KR20170087837A publication Critical patent/KR20170087837A/ko
Application granted granted Critical
Publication of KR101822784B1 publication Critical patent/KR101822784B1/ko
Publication of KR101822784B9 publication Critical patent/KR101822784B9/ko

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5058—Neurological cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
KR1020170012464A 2016-01-21 2017-01-26 신경혈관단위-온-칩 및 그 칩의 제조방법 KR101822784B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020170012464A KR101822784B1 (ko) 2016-01-21 2017-01-26 신경혈관단위-온-칩 및 그 칩의 제조방법

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020160007354 2016-01-21
KR1020170012464A KR101822784B1 (ko) 2016-01-21 2017-01-26 신경혈관단위-온-칩 및 그 칩의 제조방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020160007354 Division 2016-01-21 2016-01-21

Publications (3)

Publication Number Publication Date
KR20170087837A KR20170087837A (ko) 2017-07-31
KR101822784B1 KR101822784B1 (ko) 2018-01-30
KR101822784B9 true KR101822784B9 (ko) 2021-10-27

Family

ID=59419012

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020170012464A KR101822784B1 (ko) 2016-01-21 2017-01-26 신경혈관단위-온-칩 및 그 칩의 제조방법

Country Status (1)

Country Link
KR (1) KR101822784B1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230407220A1 (en) * 2020-11-20 2023-12-21 The Regents Of The University Of California Novel tissue culture systems and reduced gravity culture method for the production of vascularized tissue
KR102527639B1 (ko) * 2020-12-29 2023-05-03 (주) 마이크로핏 역방향 액체 급속 프린팅을 이용한 뇌혈관장벽 오간온어칩의 3차원 뇌혈관장벽 구조체 제조방법 및 이를 포함하는 뇌혈관장벽 오간온어칩
WO2022145743A1 (ko) * 2020-12-29 2022-07-07 (주) 마이크로핏 역방향 액체 급속 프린팅을 이용한 뇌혈관장벽 오간온어칩의 3차원 뇌혈관장벽 구조체 제조방법 및 이를 포함하는 뇌혈관장벽 오간온어칩
CN114480122A (zh) * 2022-01-24 2022-05-13 中国人民解放军海军军医大学 一种基于微流控芯片的血脑屏障与脑胶质瘤共培养模型的建立方法及应用
CN116478819B (zh) * 2023-06-20 2023-09-26 清华大学 一种用于构建三维器官微环境模型的微流控系统及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015116149A (ja) * 2013-12-18 2015-06-25 国立大学法人 東京大学 微小血管−組織間相互作用観察のための三次元ゲルチップ

Also Published As

Publication number Publication date
KR101822784B1 (ko) 2018-01-30
KR20170087837A (ko) 2017-07-31

Similar Documents

Publication Publication Date Title
GB2552264B (en) Integrated structure and manufacturing method thereof
IL255801A (en) Liposomal nanoconstructs and methods of making and using the same
GB2560247B (en) Microneedle and method of manufacturing the same
EP3345215A4 (en) SEMICONDUCTOR COMPONENT AND METHOD FOR THE PRODUCTION THEREOF
PL3036748T3 (pl) Induktor oraz sposób jego wytwarzania
ZA201808411B (en) Container and method of manufacturing the same
PL3322588T3 (pl) Rura wielowarstwowa i sposób jej wytwarzania
GB201900329D0 (en) Assembly and method
GB201519128D0 (en) Solid forms and methods of preparing the same
SG11202104949WA (en) Meta-lens structure and method of fabricating the same
EP3516127A4 (en) STRUCTURE AND MANUFACTURING METHOD THEREOF
KR101822784B9 (ko) 신경혈관단위-온-칩 및 그 칩의 제조방법
PL3112023T3 (pl) Materiał adsorpcyjny i sposób jego wytwarzania
PL3093358T3 (pl) Stal i sposób jej wytwarzania
EP3233124A4 (en) Nanowire-coated microdevice and method of making and using the same
GB201609584D0 (en) A de-oiler and a method of using the same
GB201502267D0 (en) Cosmetic palette assembly and method of making the same
SG10201912982VA (en) Optical structure and method of forming the same
EP3294763C0 (en) PRODUCTION OF GLUCANASE AND METHODS OF USE THEREOF
EP3209262A4 (en) Memorial object and method of making the same
SG10201503455UA (en) Interposer substrate and method of fabricating the same
GB2564196B (en) Cover and method of manufacturing the same
GB201410385D0 (en) A composite structure and a method of fabricating the same
PL3199370T3 (pl) Sposób wytwarzania i urządzenie do zastosowania sposobu wytwarzania
KR102309004B9 (ko) 폴리아크릴로니트릴계 탄소섬유 및 그의 제조방법

Legal Events

Date Code Title Description
AMND Amendment
E601 Decision to refuse application
AMND Amendment
X701 Decision to grant (after re-examination)
GRNT Written decision to grant
G170 Publication of correction