KR101770006B1 - 체외 혈액 처리 중에 대용제의 공급을 조절하는 방법 및 대용제의 공급을 조절하기 위한 부재를 포함하는 체외 혈액 처리 장치 - Google Patents

체외 혈액 처리 중에 대용제의 공급을 조절하는 방법 및 대용제의 공급을 조절하기 위한 부재를 포함하는 체외 혈액 처리 장치 Download PDF

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KR101770006B1
KR101770006B1 KR1020127011574A KR20127011574A KR101770006B1 KR 101770006 B1 KR101770006 B1 KR 101770006B1 KR 1020127011574 A KR1020127011574 A KR 1020127011574A KR 20127011574 A KR20127011574 A KR 20127011574A KR 101770006 B1 KR101770006 B1 KR 101770006B1
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dialyzer
flow resistance
inter
extracorporeal blood
dependent
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KR20120117737A (ko
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파스칼 코퍼스취미트
알프레드 가겔
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프레제니우스 메디칼 케어 도이치란드 게엠베하
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424Substitution fluid path
    • A61M1/3437Substitution fluid path downstream of the filter, e.g. post-dilution with filtrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
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    • AHUMAN NECESSITIES
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    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • A61M1/1613Profiling or modelling of patient or predicted treatment evolution or outcome
    • AHUMAN NECESSITIES
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    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • A61M1/1617Control or regulation using measurements made during a temporary variation of a characteristic of the fresh dialysis fluid
    • AHUMAN NECESSITIES
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    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • A61M1/1635Constructional aspects thereof with volume chamber balancing devices between used and fresh dialysis fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403Regulation parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403Regulation parameters
    • A61M1/341Regulation parameters by measuring the filtrate rate or volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3413Diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424Substitution fluid path
    • A61M1/3431Substitution fluid path upstream of the filter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424Substitution fluid path
    • A61M1/3431Substitution fluid path upstream of the filter
    • A61M1/3434Substitution fluid path upstream of the filter with pre-dilution and post-dilution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3627Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633Blood component filters, e.g. leukocyte filters
    • A61M1/3635Constructional details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24Dialysis ; Membrane extraction
    • B01D61/243Dialysis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24Dialysis ; Membrane extraction
    • B01D61/28Apparatus therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24Dialysis ; Membrane extraction
    • B01D61/32Controlling or regulating
    • AHUMAN NECESSITIES
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    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3327Measuring
    • AHUMAN NECESSITIES
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    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2311/00Details relating to membrane separation process operations and control
    • B01D2311/14Pressure control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
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    • B01D2311/16Flow or flux control

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
KR1020127011574A 2009-11-26 2010-11-16 체외 혈액 처리 중에 대용제의 공급을 조절하는 방법 및 대용제의 공급을 조절하기 위한 부재를 포함하는 체외 혈액 처리 장치 Active KR101770006B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009055995.7 2009-11-26
DE102009055995 2009-11-26
PCT/EP2010/006981 WO2011063906A1 (de) 2009-11-26 2010-11-16 Verfahren zum regeln der zufuhr von substituat bei einer extrakorporalen blutbehandlung und extrakorporale blutbehandlungsvorrichtung mit einer einrichtung zum regeln der zufuhr von substituat

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KR20120117737A KR20120117737A (ko) 2012-10-24
KR101770006B1 true KR101770006B1 (ko) 2017-08-21

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KR1020127011574A Active KR101770006B1 (ko) 2009-11-26 2010-11-16 체외 혈액 처리 중에 대용제의 공급을 조절하는 방법 및 대용제의 공급을 조절하기 위한 부재를 포함하는 체외 혈액 처리 장치

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US (2) US11376353B2 (https=)
EP (1) EP2504044B2 (https=)
JP (1) JP5753538B2 (https=)
KR (1) KR101770006B1 (https=)
CN (1) CN102665791B (https=)
AU (1) AU2010324153B2 (https=)
CA (1) CA2778204C (https=)
ES (1) ES2564104T5 (https=)
PL (1) PL2504044T5 (https=)
WO (1) WO2011063906A1 (https=)

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WO2011063906A1 (de) 2009-11-26 2011-06-03 Fresenius Medical Care Deutschland Gmbh Verfahren zum regeln der zufuhr von substituat bei einer extrakorporalen blutbehandlung und extrakorporale blutbehandlungsvorrichtung mit einer einrichtung zum regeln der zufuhr von substituat
DE102011112221B4 (de) * 2011-09-02 2017-05-24 Fresenius Medical Care Deutschland Gmbh Blutbehandlungsvorrichtung
DE102012004970A1 (de) * 2012-03-14 2013-09-19 Fresenius Medical Care Deutschland Gmbh Verfahren zum Dosieren eines mittels einer Blutbehandlungsvorrichtung erzeugten Substituats sowie Vorrichtungen
DE102014008546B4 (de) * 2014-06-16 2021-12-16 Günter Heeke Haemofiltrationsgerät, Schlauchset und dessen Verwendung und Verfahren zum Betrieb eines Haemofiltationsgeräts
EP3646336B1 (en) 2017-06-28 2023-06-28 Gambro Lundia AB A system and a method for renal replacement therapy
CN113474019A (zh) 2018-07-20 2021-10-01 费森尤斯医疗护理德国有限责任公司 中央控制式多患者透析治疗系统及其用途
US11491267B2 (en) 2018-07-27 2022-11-08 Fresenius Medical Care Holdings, Inc. Method for tailoring dialysis treatment based on sensed potassium concentration in blood serum or dialysate
DE102019124990A1 (de) 2019-09-17 2021-03-18 B.Braun Avitum Ag Blutbehandlungsvorrichtung mit automatischer Verringerung einer Substitutionslösungsflussrate
US20230211057A1 (en) * 2020-05-20 2023-07-06 Nipro Corporation Method of monitoring blood circulation, dialysis device, and non-transitory computer-readable storage medium

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US20120318739A1 (en) 2012-12-20
US11376353B2 (en) 2022-07-05
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PL2504044T3 (pl) 2016-09-30
CN102665791B (zh) 2015-08-19
CA2778204A1 (en) 2011-06-03
ES2564104T5 (es) 2024-05-08
ES2564104T3 (es) 2016-03-17
AU2010324153A1 (en) 2012-07-12
WO2011063906A1 (de) 2011-06-03
PL2504044T5 (pl) 2024-11-18
JP5753538B2 (ja) 2015-07-22
EP2504044B1 (de) 2016-01-27
US20220280707A1 (en) 2022-09-08
CA2778204C (en) 2019-10-15
AU2010324153B2 (en) 2015-05-14
JP2013512012A (ja) 2013-04-11
US12337093B2 (en) 2025-06-24
EP2504044B2 (de) 2023-10-04
CN102665791A (zh) 2012-09-12

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