KR101757003B1 - 인지 장애를 치료하기 위한 콜린에스테라아제 저해물질을 포함한 조성물 - Google Patents

인지 장애를 치료하기 위한 콜린에스테라아제 저해물질을 포함한 조성물 Download PDF

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KR101757003B1
KR101757003B1 KR1020127003979A KR20127003979A KR101757003B1 KR 101757003 B1 KR101757003 B1 KR 101757003B1 KR 1020127003979 A KR1020127003979 A KR 1020127003979A KR 20127003979 A KR20127003979 A KR 20127003979A KR 101757003 B1 KR101757003 B1 KR 101757003B1
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cholinesterase inhibitor
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galantamine
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KR20120090029A (ko
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우르술라 브이. 스토브리
존 이. 도넬로
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알러간, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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  • Pain & Pain Management (AREA)
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  • Hospice & Palliative Care (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
KR1020127003979A 2009-07-17 2010-07-16 인지 장애를 치료하기 위한 콜린에스테라아제 저해물질을 포함한 조성물 Active KR101757003B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22642509P 2009-07-17 2009-07-17
US61/226,425 2009-07-17
PCT/US2010/042308 WO2011009061A1 (en) 2009-07-17 2010-07-16 Compositions comprising a cholinesterase inhibitor for treating cognitive disorders

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KR20120090029A KR20120090029A (ko) 2012-08-16
KR101757003B1 true KR101757003B1 (ko) 2017-07-11

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US (2) US20110015179A1 (enExample)
EP (1) EP2453890B1 (enExample)
JP (1) JP2012533566A (enExample)
KR (1) KR101757003B1 (enExample)
CN (1) CN102497861A (enExample)
AU (1) AU2010273977A1 (enExample)
BR (1) BR112012001047A2 (enExample)
CA (1) CA2768356A1 (enExample)
DK (1) DK2453890T3 (enExample)
ES (1) ES2809298T3 (enExample)
IN (1) IN2012DN01209A (enExample)
PT (1) PT2453890T (enExample)
RU (2) RU2016151986A (enExample)
WO (1) WO2011009061A1 (enExample)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008109610A1 (en) * 2007-03-06 2008-09-12 Allergan, Inc. Methods for treating cognitive disorders using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds
WO2008109287A1 (en) 2007-03-06 2008-09-12 Allergan, Inc. Methods for treating cognitive disorders using 1-benzyl-1-hydroxy-2,3-diamino-propyl amines, 3-benzyl-3-hydroxy-2-amino-propionic acid amides and related compounds
WO2008109285A1 (en) 2007-03-06 2008-09-12 Allergan, Inc. Methods for treating cognitive disorders

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US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
US4166452A (en) * 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) * 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US5409948A (en) * 1992-11-23 1995-04-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method for treating cognitive disorders with phenserine
US20050222123A1 (en) * 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
US20070212253A1 (en) * 2004-12-21 2007-09-13 Elrod Scott A Descenting systems and methods
PL383715A1 (pl) 2005-01-26 2008-05-12 Allergan, Inc. Amidy kwasu 3-arylo-3-hydroksy-2-amino-propionowego, amidy kwasu 3-heteroarylo-3-hydroksy-2-amino-propionowego i ich związki pokrewne posiadające aktywność przeciwbólową i/lub pobudzającą odporność
WO2007012154A1 (en) * 2005-07-27 2007-02-01 Carlos Henrique Horta Lima Pharmaceutical preparation containing an acetylcholinesterase ihibitor and an antidepressant with 5-ht and alpha-2-adrenoceptor blocking properties.
EP2275096A3 (en) * 2005-08-26 2011-07-13 Braincells, Inc. Neurogenesis via modulation of the muscarinic receptors
WO2008109286A1 (en) * 2007-03-06 2008-09-12 Allergan, Inc. Methods for treating cognitive disorders using 1-aryl-1-hydroxy-2,3-diamino-propyl amines, 1-heteroaryl-1-hydroxy-2,3-diamino-propyl amines and related compounds
CA2693369A1 (en) * 2007-07-17 2009-01-22 Allergan, Inc. Methods for treating anxiety

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2008109610A1 (en) * 2007-03-06 2008-09-12 Allergan, Inc. Methods for treating cognitive disorders using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds
WO2008109287A1 (en) 2007-03-06 2008-09-12 Allergan, Inc. Methods for treating cognitive disorders using 1-benzyl-1-hydroxy-2,3-diamino-propyl amines, 3-benzyl-3-hydroxy-2-amino-propionic acid amides and related compounds
WO2008109285A1 (en) 2007-03-06 2008-09-12 Allergan, Inc. Methods for treating cognitive disorders

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Publication number Publication date
KR20120090029A (ko) 2012-08-16
US20110015179A1 (en) 2011-01-20
RU2012103401A (ru) 2013-08-27
JP2012533566A (ja) 2012-12-27
CA2768356A1 (en) 2011-01-20
US20130040938A1 (en) 2013-02-14
EP2453890A1 (en) 2012-05-23
PT2453890T (pt) 2020-08-25
AU2010273977A1 (en) 2012-02-02
IN2012DN01209A (enExample) 2015-04-10
RU2607946C2 (ru) 2017-01-11
US9492543B2 (en) 2016-11-15
RU2016151986A (ru) 2018-12-19
ES2809298T3 (es) 2021-03-03
CN102497861A (zh) 2012-06-13
BR112012001047A2 (pt) 2019-09-24
WO2011009061A1 (en) 2011-01-20
DK2453890T3 (da) 2020-08-17
EP2453890B1 (en) 2020-05-27

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