KR101711860B1 - 발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템 - Google Patents

발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템 Download PDF

Info

Publication number
KR101711860B1
KR101711860B1 KR1020157030263A KR20157030263A KR101711860B1 KR 101711860 B1 KR101711860 B1 KR 101711860B1 KR 1020157030263 A KR1020157030263 A KR 1020157030263A KR 20157030263 A KR20157030263 A KR 20157030263A KR 101711860 B1 KR101711860 B1 KR 101711860B1
Authority
KR
South Korea
Prior art keywords
protein
tissue sample
cancer
kit
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020157030263A
Other languages
English (en)
Korean (ko)
Other versions
KR20150123344A (ko
Inventor
니븐 라진 나레인
인더세카르 퍼사우드
Original Assignee
베르그 엘엘씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 베르그 엘엘씨 filed Critical 베르그 엘엘씨
Publication of KR20150123344A publication Critical patent/KR20150123344A/ko
Application granted granted Critical
Publication of KR101711860B1 publication Critical patent/KR101711860B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G01N33/574—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/50—Fibroblast growth factors [FGF]
    • G01N2333/503—Fibroblast growth factors [FGF] basic FGF [bFGF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
KR1020157030263A 2008-01-25 2009-01-26 발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템 Expired - Fee Related KR101711860B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2357008P 2008-01-25 2008-01-25
US61/023,570 2008-01-25
PCT/US2009/031957 WO2009094619A1 (en) 2008-01-25 2009-01-26 Assay system for the assessment of oncogenicity, tumor progression, and treatment efficacy

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020107018492A Division KR101714359B1 (ko) 2008-01-25 2009-01-26 발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템

Publications (2)

Publication Number Publication Date
KR20150123344A KR20150123344A (ko) 2015-11-03
KR101711860B1 true KR101711860B1 (ko) 2017-03-03

Family

ID=40901454

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020157030263A Expired - Fee Related KR101711860B1 (ko) 2008-01-25 2009-01-26 발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템
KR1020107018492A Expired - Fee Related KR101714359B1 (ko) 2008-01-25 2009-01-26 발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020107018492A Expired - Fee Related KR101714359B1 (ko) 2008-01-25 2009-01-26 발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템

Country Status (7)

Country Link
US (1) US10365279B2 (enExample)
EP (2) EP2245460B1 (enExample)
JP (3) JP2011511271A (enExample)
KR (2) KR101711860B1 (enExample)
AU (1) AU2009206289A1 (enExample)
ES (2) ES2453161T3 (enExample)
WO (1) WO2009094619A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
KR101765999B1 (ko) 2015-01-21 2017-08-08 서울대학교산학협력단 암 바이오마커의 성능 평가 장치 및 방법
CA3126432A1 (en) * 2019-02-01 2020-08-06 Health Research, Inc. Methods and compositions for treating resistant and recurrent forms of cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040133352A1 (en) 1999-06-28 2004-07-08 Michael Bevilacqua Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
WO2005103281A2 (en) * 2004-04-26 2005-11-03 Children's Medical Center Corporation Platelet biomarkers for the detection of disease

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19736691A1 (de) 1997-08-22 1999-02-25 Michael Prof Dr Med Giesing Verfahren zur Charakterisierung und Identifizierung disseminierter und metastasierter Krebszellen
AU2002216009A1 (en) 2000-11-03 2002-05-15 Michael Giesing Clinical and functional validation of targets from disseminated cancer cells
US20030138792A1 (en) * 2001-05-31 2003-07-24 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention and therapy of cervical cancer
CN102402650A (zh) 2001-11-09 2012-04-04 生命技术公司 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态
US20030235816A1 (en) 2002-03-14 2003-12-25 Baylor College Of Medicine (By Slawin And Shariat) Method to determine outcome for patients with prostatic disease
FR2840923B1 (fr) 2002-06-17 2007-07-06 Centre Nat Rech Scient Agent anti-resistance a l'oxaliplatine
WO2003106974A2 (en) 2002-06-18 2003-12-24 Irm Llc Diagnosis and treatment of chemoresistant tumors
EP1507148B1 (en) 2003-08-25 2005-02-23 MTM Laboratories AG Method for detecting carcinomas in a solubilized cervical body sample
CA2561513C (en) 2004-03-29 2019-02-26 University Of South Florida Effective treatment of tumors and cancer with triciribine and related compounds
WO2006022895A2 (en) 2004-08-02 2006-03-02 Children's Medical Center Corporation Platelet biomarkers for cancer
EP2302388A1 (en) * 2004-10-14 2011-03-30 Genentech, Inc. COP1 molecules and uses thereof
WO2007137187A2 (en) * 2006-05-18 2007-11-29 Molecular Profiling Institute, Inc. System and method for determining individualized medical intervention for a disease state

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040133352A1 (en) 1999-06-28 2004-07-08 Michael Bevilacqua Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
WO2005103281A2 (en) * 2004-04-26 2005-11-03 Children's Medical Center Corporation Platelet biomarkers for the detection of disease

Also Published As

Publication number Publication date
JP2011511271A (ja) 2011-04-07
JP2015052605A (ja) 2015-03-19
JP2017102125A (ja) 2017-06-08
EP2245460A1 (en) 2010-11-03
EP2708894A3 (en) 2014-04-02
EP2708894B1 (en) 2016-07-06
AU2009206289A1 (en) 2009-07-30
WO2009094619A1 (en) 2009-07-30
EP2245460A4 (en) 2011-05-25
EP2245460B1 (en) 2013-12-25
US20110027811A1 (en) 2011-02-03
EP2708894A2 (en) 2014-03-19
KR20100131435A (ko) 2010-12-15
ES2589506T3 (es) 2016-11-14
US10365279B2 (en) 2019-07-30
ES2453161T3 (es) 2014-04-04
KR101714359B1 (ko) 2017-03-09
HK1150401A1 (en) 2011-12-23
KR20150123344A (ko) 2015-11-03
JP6087888B2 (ja) 2017-03-01

Similar Documents

Publication Publication Date Title
Williams et al. Prognostic significance and predictors of the neutrophil-to-lymphocyte ratio in ovarian cancer
KR101714359B1 (ko) 발암성, 종양 진행 및 치료 효능을 평가하는 분석 시스템
Boegemann et al. The percentage of prostate‐specific antigen (PSA) isoform [–2] pro PSA and the Prostate Health Index improve the diagnostic accuracy for clinically relevant prostate cancer at initial and repeat biopsy compared with total PSA and percentage free PSA in men aged≤ 65 years
Yang et al. Prognostic value of Ki-67 in solid pseudopapillary tumor of the pancreas: Huashan experience and systematic review of the literature
Saab et al. Utility of genomic analysis in differentiating synchronous and metachronous lung adenocarcinomas from primary adenocarcinomas with intrapulmonary metastasis
Brück et al. Spatial immunoprofiling of the intratumoral and peritumoral tissue of renal cell carcinoma patients
Jaafari-Ashkavandi et al. MCM3 and Ki67 proliferation markers in odontogenic cysts and ameloblastoma
Fritz-Rdzanek et al. HE4 protein and SMRP: Potential novel biomarkers in ovarian cancer detection
Porter et al. Novel biomarkers for risk stratification of Barrett’s oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype
Naik Role of biomarkers in the integrated management of melanoma
Wang et al. The significance of preoperative neutrophil-to-lymphocyte ratio in predicting short-term complications and survival benefits of pancreaticoduodenectomy: A systematic review and meta-analysis
Liu et al. Immune and inflammation: related factor alterations as biomarkers for predicting prognosis and responsiveness to PD-1 monoclonal antibodies in cervical cancer
Levine et al. Current status of diagnostic and prognostic markers in melanoma
Karaburun et al. Investigation of atypical cell parameter in the surveillance of patients with NMIBC; initial outcomes of a single center prospective study
Serra et al. Cyclooxygenase-2 (COX2) and p53 protein expression are interdependent in breast cancer but not associated with clinico-pathological surrogate subtypes, tumor aggressiveness and patient survival.
Nassir et al. HE4 tissue expression in borderline ovarian tumors: a pilot study by the tumorbank ovarian cancer network
AU2015203304B2 (en) Assay system for the assessment of oncogenicity, tumor progression, and treatment efficacy
Udiyanto et al. A cohort study: caspase-3 as prognostic factor of radiation therapy in the advanced stage of cervical cancer (IIB-IIIB) patients
Ponti et al. Value and prognostic significance of mitotic rate in a retrospective series of pT1 cutaneous malignant melanoma patients
Yang et al. Prognostic value of lymphocyte-to-monocyte ratio in patients with small cell lung cancer: a meta-analysis
Tirić et al. Immunohistochemical expression and predictive value of PAX3 and FOXO1 proteins in high-grade serous ovarian carcinoma.
HK1195623A (en) Assay system for the assessment of oncogenicity, tumor progression, and treatment efficacy
HK1195623B (en) Assay system for the assessment of oncogenicity, tumor progression, and treatment efficacy
HK1150401B (en) Assay system for the assessment of oncogenicity, tumor progression, and treatment efficacy
Dai et al. Matrix metalloproteinase 9 for evaluating invasiveness and recurrence in pituitary adenoma patients: A Meta-analysis

Legal Events

Date Code Title Description
A107 Divisional application of patent
PA0104 Divisional application for international application

St.27 status event code: A-0-1-A10-A16-div-PA0104

St.27 status event code: A-0-1-A10-A18-div-PA0104

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

Fee payment year number: 1

St.27 status event code: A-2-2-U10-U12-oth-PR1002

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000

PC1903 Unpaid annual fee

Not in force date: 20200225

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

St.27 status event code: A-4-4-U10-U13-oth-PC1903

PC1903 Unpaid annual fee

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20200225

St.27 status event code: N-4-6-H10-H13-oth-PC1903

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000