KR101683643B1 - 시아이에스-단일불포화 지방산의 알파-유도체 및 이의 의약으로서의 용도 - Google Patents
시아이에스-단일불포화 지방산의 알파-유도체 및 이의 의약으로서의 용도 Download PDFInfo
- Publication number
- KR101683643B1 KR101683643B1 KR1020117014462A KR20117014462A KR101683643B1 KR 101683643 B1 KR101683643 B1 KR 101683643B1 KR 1020117014462 A KR1020117014462 A KR 1020117014462A KR 20117014462 A KR20117014462 A KR 20117014462A KR 101683643 B1 KR101683643 B1 KR 101683643B1
- Authority
- KR
- South Korea
- Prior art keywords
- cis
- octadecenoic acid
- hydroxy
- ohod
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200803480A ES2342997B1 (es) | 2008-12-09 | 2008-12-09 | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
| ESP200803480 | 2008-12-09 | ||
| PCT/ES2009/070561 WO2010066931A1 (es) | 2008-12-09 | 2009-12-04 | Alfa-derivados de ácidos grasos cis-monoinsaturados para ser usados como medicamento |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20110126100A KR20110126100A (ko) | 2011-11-22 |
| KR101683643B1 true KR101683643B1 (ko) | 2016-12-07 |
Family
ID=42242375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020117014462A Expired - Fee Related KR101683643B1 (ko) | 2008-12-09 | 2009-12-04 | 시아이에스-단일불포화 지방산의 알파-유도체 및 이의 의약으로서의 용도 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9000042B2 (https=) |
| EP (4) | EP2842555B1 (https=) |
| JP (2) | JP5711140B2 (https=) |
| KR (1) | KR101683643B1 (https=) |
| CN (1) | CN102355897B (https=) |
| AU (6) | AU2009326993B2 (https=) |
| BR (1) | BRPI0922870A8 (https=) |
| CA (1) | CA2745052C (https=) |
| DK (3) | DK2842556T3 (https=) |
| ES (5) | ES2342997B1 (https=) |
| HU (2) | HUE056170T2 (https=) |
| IL (1) | IL213354A (https=) |
| MX (1) | MX2011005978A (https=) |
| PL (3) | PL3366285T3 (https=) |
| PT (4) | PT2374453E (https=) |
| RU (1) | RU2531353C2 (https=) |
| SI (1) | SI3366285T1 (https=) |
| WO (1) | WO2010066931A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2342997B1 (es) | 2008-12-09 | 2011-06-06 | Universitat De Les Illes Balears | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
| WO2011089265A1 (en) * | 2010-01-25 | 2011-07-28 | Bridge Bioresearch Plc | Use of fatty acid compounds for lowering blood glucose levels |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
| WO2013132092A1 (en) * | 2012-03-09 | 2013-09-12 | Pensieve International Plc | Use of monounsaturated fatty acid compounds for controlling the body weight of a dog or a cat |
| WO2016062746A1 (en) * | 2014-10-21 | 2016-04-28 | Universitat De Les Illes Balears | Method for the synthesis of hydroxy-triglycerides and uses thereof for the prevention and treatment of diseases |
| WO2019099664A1 (en) * | 2017-11-16 | 2019-05-23 | The Research Foundation For The State University Of New York | Use of 2-hydroxyoleic acid for the treatment of systemic lupus erythematosus and other immune pathologies |
| CN115052852A (zh) * | 2020-01-29 | 2022-09-13 | 巴利阿里群岛大学 | α-羟基化脂肪酸代谢产物、其医学用途以及作为生物标志物的用途 |
| ES2911474B2 (es) * | 2020-11-17 | 2023-02-06 | Univ Illes Balears | Profarmacos de acidos grasos monoinsaturados y sus metabolitos: usos medicos y como biomarcadores |
| US12440467B2 (en) * | 2021-12-09 | 2025-10-14 | The Florida International University Board Of Trustees | Treatment and prevention of infections using vegetable oil-derived polyols |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4928172B1 (https=) * | 1969-10-27 | 1974-07-24 | ||
| CH558321A (de) * | 1971-08-03 | 1975-01-31 | Ciba Geigy Ag | Verfahren zur herstellung von carbonsaeuren bezw. carbonsaeuresalzen. |
| US3931306A (en) * | 1973-10-23 | 1976-01-06 | International Flavors & Fragrances Inc. | Process for producing isomer mixtures containing high proportions of cis-2-methyl-3-pentenoic acid |
| DE2448339A1 (de) * | 1974-10-10 | 1976-04-22 | Basf Ag | Verfahren zur herstellung von olefinisch ungesaettigten carbonsaeureestern |
| DE2559201B2 (de) * | 1975-12-30 | 1978-06-15 | Hoechst Ag, 6000 Frankfurt | Organozinnverbindungen und ihre Verwendung als Stabilisatoren |
| US4241097A (en) * | 1979-09-13 | 1980-12-23 | International Flavors & Fragrances Inc. | Use of benzodionones in augmenting or enhancing the aroma and taste of a foodstuff |
| US4391757A (en) * | 1981-11-27 | 1983-07-05 | Carstab Corporation | Organic antimony containing stabilizer compositions for halogenated polymers |
| JPS5899432A (ja) * | 1981-12-09 | 1983-06-13 | Maruzen Sekiyu Kagaku Kk | 不飽和脂肪酸またはその塩およびそれからなる抗菌剤 |
| US4551279A (en) * | 1984-01-09 | 1985-11-05 | G. D. Searle & Co. | Protease inhibitors |
| FR2609032B1 (fr) * | 1986-12-30 | 1990-01-05 | Centre Nat Rech Scient | Epoxydes fonctionnels enantiomeriquement purs, leur procede de preparation et leur application comme synthons chiraux |
| US4808403A (en) * | 1987-03-17 | 1989-02-28 | International Flavors & Fragrances Inc. | Use of N,N-diethyl-m-toluamide and/or the ethyl ester of 2-methyl-3-pentenoic acid as insect attractants |
| US5504107A (en) | 1990-01-12 | 1996-04-02 | The Ohio State University Research Foundation | Optically pure 4-alkenyl- or 4-alkanyl-2-hydroxytetronic acids and pharmaceutical use thereof |
| GB9003201D0 (en) * | 1990-02-13 | 1990-04-11 | Unilever Plc | Cosmetic composition |
| US5208260A (en) * | 1990-03-29 | 1993-05-04 | G. D. Searle & Co. | Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder |
| US5198250A (en) * | 1990-07-16 | 1993-03-30 | Lipotech Partners Limited Partnership | Food and pharmaceutical compositions containing short chain monounsaturated fatty acids and methods of using |
| ES2039336T3 (es) * | 1991-04-10 | 1999-08-01 | Yu Ruey J | Uso de composiciones cosmeticas que contienen acidos 2-hidroxicarboxilicos y compuestos afines para aliviar los indicios de cambios de las uñas. |
| US6300373B1 (en) | 1993-09-10 | 2001-10-09 | American Biogenetic Sciences, Inc. | Antiproliferative and neurotrophic molecules |
| JP3489703B2 (ja) * | 1995-10-23 | 2004-01-26 | 株式会社ノエビア | 微細エマルション組成物 |
| US5856537A (en) * | 1996-06-26 | 1999-01-05 | The Scripps Research Institute | Inhibitors of oleamide hydrolase |
| JPH10182338A (ja) * | 1996-12-20 | 1998-07-07 | Noevir Co Ltd | 水中油型乳化組成物 |
| JP2001523695A (ja) * | 1997-11-24 | 2001-11-27 | ザ スクリップス リサーチ インスティテュート | ギャップ結合連絡の阻害剤 |
| GB9926833D0 (en) * | 1999-11-15 | 2000-01-12 | Univ Sunderland | Compositions |
| GB2385589A (en) * | 2000-08-07 | 2003-08-27 | Sofitech Nv | Surfactant |
| ES2186576B1 (es) | 2001-10-11 | 2004-09-16 | Universitat De Les Illes Balears | Acido 2-hidroxioleico para utilizar como medicamento. |
| US6702756B2 (en) * | 2001-12-11 | 2004-03-09 | University Technologies International Inc. | Method and apparatus for diagnosing neurological impairment |
| BR0306957A (pt) | 2002-01-22 | 2004-12-14 | Syngenta Participations Ag | Herbicidas |
| US7462349B2 (en) * | 2002-10-24 | 2008-12-09 | Nurit Kalderon | Beta interferon for the treatment of chronic spinal cord injury |
| US20040214215A1 (en) * | 2003-03-07 | 2004-10-28 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
| EP1622633B1 (en) * | 2003-05-15 | 2016-02-24 | Ampio Pharmaceuticals, Inc. | Treatment of t-cell mediated diseases |
| ES2229935B1 (es) * | 2003-10-10 | 2006-10-01 | Universitat De Les Illes Balears | Utilizacion del acido hidroxioleico y compuestos analagos del mismo como aditivos alimentarios funcionales. |
| KR100756890B1 (ko) * | 2005-08-19 | 2007-09-07 | 경희대학교 산학협력단 | 신경세포 보호활성을 갖는 올레산을 함유하는 조성물 |
| JP2009051732A (ja) * | 2005-12-13 | 2009-03-12 | Meiji Seika Kaisha Ltd | Pparリガンド活性を有する組成物 |
| WO2009127009A1 (en) | 2008-04-18 | 2009-10-22 | Commonwealth Scientific And Industrial Research Organisation | Condensation polymers |
| JP2011516697A (ja) | 2008-04-18 | 2011-05-26 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション | ポリウレタン |
| ES2342997B1 (es) | 2008-12-09 | 2011-06-06 | Universitat De Les Illes Balears | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
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2008
- 2008-12-09 ES ES200803480A patent/ES2342997B1/es active Active
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2009
- 2009-12-04 ES ES14195394.3T patent/ES2673406T3/es active Active
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- 2009-12-04 US US13/132,231 patent/US9000042B2/en active Active
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- 2009-12-04 DK DK14195436.2T patent/DK2842556T3/en active
- 2009-12-04 ES ES18164265T patent/ES2899274T3/es active Active
- 2009-12-04 MX MX2011005978A patent/MX2011005978A/es active IP Right Grant
- 2009-12-04 PT PT98315047T patent/PT2374453E/pt unknown
- 2009-12-04 PL PL18164265T patent/PL3366285T3/pl unknown
- 2009-12-04 PL PL09831504T patent/PL2374453T3/pl unknown
- 2009-12-04 ES ES09831504.7T patent/ES2535498T3/es active Active
- 2009-12-04 EP EP14195394.3A patent/EP2842555B1/en active Active
- 2009-12-04 HU HUE18164265A patent/HUE056170T2/hu unknown
- 2009-12-04 DK DK18164265.3T patent/DK3366285T3/da active
- 2009-12-04 EP EP14195436.2A patent/EP2842556B1/en active Active
- 2009-12-04 JP JP2011539060A patent/JP5711140B2/ja active Active
- 2009-12-04 PT PT141953943T patent/PT2842555T/pt unknown
- 2009-12-04 DK DK09831504.7T patent/DK2374453T3/en active
- 2009-12-04 WO PCT/ES2009/070561 patent/WO2010066931A1/es not_active Ceased
- 2009-12-04 RU RU2011128335/04A patent/RU2531353C2/ru active
- 2009-12-04 KR KR1020117014462A patent/KR101683643B1/ko not_active Expired - Fee Related
- 2009-12-04 HU HUE14195436A patent/HUE037396T2/hu unknown
- 2009-12-04 PT PT141954362T patent/PT2842556T/pt unknown
- 2009-12-04 PT PT18164265T patent/PT3366285T/pt unknown
- 2009-12-04 CA CA2745052A patent/CA2745052C/en not_active Expired - Fee Related
- 2009-12-04 EP EP09831504.7A patent/EP2374453B1/en active Active
- 2009-12-04 EP EP18164265.3A patent/EP3366285B1/en active Active
- 2009-12-04 CN CN200980156029.6A patent/CN102355897B/zh active Active
- 2009-12-04 PL PL14195436T patent/PL2842556T3/pl unknown
- 2009-12-04 BR BRPI0922870A patent/BRPI0922870A8/pt not_active Application Discontinuation
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2011
- 2011-06-05 IL IL213354A patent/IL213354A/en active IP Right Grant
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2014
- 2014-11-14 JP JP2014232196A patent/JP2015061856A/ja active Pending
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2015
- 2015-03-20 US US14/664,351 patent/US9730906B2/en active Active
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2016
- 2016-09-13 AU AU2016228171A patent/AU2016228171A1/en not_active Abandoned
- 2016-09-13 AU AU2016228167A patent/AU2016228167A1/en not_active Abandoned
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2017
- 2017-07-10 US US15/645,524 patent/US10588883B2/en active Active
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2018
- 2018-09-12 AU AU2018229474A patent/AU2018229474B2/en active Active
- 2018-09-12 AU AU2018229472A patent/AU2018229472B2/en active Active
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2019
- 2019-08-30 AU AU2019222955A patent/AU2019222955B2/en active Active
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