KR101667021B1

KR101667021B1 - Method for preparing functional pills with nyoa fruticans and functional pills by the method

Info

Publication number: KR101667021B1
Application number: KR1020160051215A
Authority: KR
Inventors: 김월곤; 김용덕; 최해종; 이영희
Original assignee: 농업회사법인 자연 주식회사
Priority date: 2016-04-27
Filing date: 2016-04-27
Publication date: 2016-10-20

Abstract

The present invention relates to a method for manufacturing functional pills with nipa palm and functional pills manufactured thereby, the method comprising the following steps: preparing a nipa palm sap concentrate; making flower stalks of nipa palm into powder; mixing the prepared sap concentrate and the powder of flower stalks of nipa palm; forming the mixed mixture into pills; coating edible gold powder on the surface for the formed pills; and drying the pills coated with the gold powder. According to the present invention, antioxidative activity and anti-inflammatory effect of a sap concentrate, flower stalks, etc. of nipa palm helps a person taking the functional pills to maintain his/her health.

Description

METHOD FOR PREPARING FUNCTIONALLY ROLLED FUNCTIONAL PILLS WITH NIPAJAZA AND FUNCTIONAL PLANNING THEREOF Technical Field [

The present invention relates to a method for producing a functional ring using nipaya and a functional ring thereof, and more particularly, to a method for producing a functional ring using nipaya as a nutritional supplement, And a functional ring thereof.

In general, it is not surprising that anyone who wants to live a healthy life without disease.

However, modern people are suffering from the immaturity of the human body due to heavy work, excessive drinking, overwork, irregular eating, lack of exercise, stress, pollution and other external environmental factors. Such a decrease in the immune function of the human body is a problem directly related to health.

As described above, according to the decline of the immune function, modern people living in the modern world are taking all kinds of measures to improve the immunity of the human body in preparation for the right of health and the abnormality of health that may occur in the future. In addition to investment, there is also a lot of spending on the economic side.

The most active effort by modern people to improve the body 's immunity is to take exercise and health supplements. These exercises and health supplements are most often used as a means of maintaining health because they are less time and economic burdens than others.

Especially, in the case of health supplements, many kinds of things are around our life, so they can be taken according to their health condition or taste. These health supplements are intended to be used for the purpose of consuming in the physical and physiological aspects of the body, in order to consume the ingredients contained in the food material as they are, or to separate or extract specific components contained therein, concentrate, refine, Which is manufactured and processed.

However, most of these health supplements are distributed in the market as liquid vacuum packs, and many inconveniences are involved in taking and carrying them. In particular, people who do not like liquids have difficulties in taking them, and even when carrying them, liquid-phase vacuum packaging is subject to many restrictions.

Therefore, in order to solve such a problem, circulation type health supplement foods have been released, thereby solving the inconvenience of taking or the inconvenience of carrying.

As the above-mentioned annular health supplement food, there are the following conventional techniques.

First, Korean Patent No. 10-0705740 proposes a method of molding a lactic acid bacterium and a cheonggukjang into a ring using a ventilator and drying to produce a functional ring. Korean Patent No. 10-1083458 proposes a method for producing a ring containing black garlic as an active ingredient and suggests a method for producing a ring by mixing black gum, Respectively. Korean Patent No. 10-1552389 proposes a method of manufacturing a ring using ginger and bamboo salt.

All of the above-mentioned manufacturing methods have solved the inconvenience of taking and carrying.

However, none of the above prior arts have found an example of producing a ring using nipaya.

KR 10-0705740 B1 KR 10-1083458 B1 KR 10-1552389 B1

Accordingly, an object of the present invention is to provide an antioxidative and anti-inflammatory effect by producing a ring using a liquid concentrate and flower bud of NiPhaya.

It is also an object of the present invention to replace the use of steroid drugs.

In order to accomplish the above object, the present invention provides a functional ring using nipaya, comprising the steps of: preparing a nipah yam liquid concentrate; preparing a nipaya flower bud as a powder; and adding the prepared liquid concentrate and nipaya flower powder Mixing the mixture to form a mixture; molding the mixed mixture into a circle; applying edible gold powder to the surface of the formed ring; and drying the ring coated with the gold powder. do.

The step of preparing the nipponia saliva liquid concentrate is characterized in that the sap is obtained from the nipponia palmarium and the resulting sap is heated at 60 to 80 ° C for 2 to 4 hours to be concentrated to have a sugar content of 60 to 80 brix.

The step of making the flower bud of the nepalaya as powder comprises the steps of cutting the flower bud of nifaya, the step of tipping the flower bud of the cut nifaya into boiling water, drying the flower bud of the nepaya flower, And pulverizing the flower bud of the dried nipayanas.

The mixing of the prepared liquid concentrate and the powder is characterized in that the liquid concentrate and the powder are mixed at a weight ratio of 1: 0.5 to 1.5.

And the flower bud is made into a powder together with the flower bud of Nipaya.

The functional ring according to the present invention is characterized by being manufactured by the above-described methods.

According to the present invention, an antioxidative activity and an anti-inflammatory effect of a liquid concentrate, a flower bud, etc. of NiPhaya have an advantage of helping the health of the consumer.

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a process flow diagram for the production of a functional ring using nipahazite according to the present invention. Fig.
2 to 5 are graphs showing the results according to Test Example 2 of the present invention.

Hereinafter, the present invention will be described in detail.

The functional ring of the present invention has antioxidant and anti-inflammatory effects, and has an effect of imparting excellent antioxidative and anti-inflammatory properties to the human body just by ingesting the ring as a health supplement.

Such a functional ring of the present invention is prepared using nipaya.

Here, the Nypa fruticans originate in India, Malaysia, Southeast Asia and Australia, and grow in wetlands such as mangroves. The roots are divided into several pieces in the ground, and the leaves are gathered on the ground and have glossy green. And the flower is one male and one female, and it comes out from the axilla of the ground. Usually, the flower stands rise from October to June of the following year.

The reason for using the flower buds of Nipaya is that it has abundant antioxidant components such as polyphenols in the flower bud than any other part of Nipaya, Selenium and other nutritional components, as well as show excellent anti-inflammatory effect.

The results of the analysis and the results of the components of the above-mentioned Nihonpalaceae are shown in the following Tables 1 and 2. As shown in Table 1 and Table 2, the Niha-Paya's peduncle contains a large amount of effective components such as polyphenol, flavonoid, saponin, as well as aspartic acid, tyrosine and histidine .

The results of analysis of the components of. Inspection items unit test results Inspection items unit test results moisture % 20.54 Selenium Mu g / kg 154.57 Crude protein % 11.65 manganese mg / kg 82.58 Crude fat % 0.73 Goat mg / kg 18344.65 Views min % 7.95 sulfur mg / kg 3221.83 carbohydrate % 59.15 salt mg / kg 6832.66 calorie kcal / 100g 289.77 Crude saponin mg / kg 110161.07 calcium mg / kg 3009.62 Total polyphenol Brix 173443.90 sign mg / kg 2589.65 Total flavonoid mg / kg 616.24 iron mg / kg 119.57 Per capita % 11.84 potassium mg / kg 26211.57 And sugar % 1.57 magnesium mg / kg 4670.47 glucose % 1.11 Copper mg / kg 0.26 saccharose % 1.19 zinc mg / kg 14.13

Test results of the components of the nipponia palm. Inspection items unit test results Aspartic acid mg / kg 269.01 Threonine mg / kg 30.22 Serine mg / kg 30.59 Glutamic acid mg / kg 171.29 Proline mg / kg 0 Glycine mg / kg 7.98 Alanine mg / kg 25.69 Balin mg / kg 49.06 Isoleucine mg / kg 39.30 Leucine mg / kg 49.73 Tyrosine mg / kg 0 Phenylmalanine mg / kg 14.70 Histidine mg / kg 13.44 Lysine mg / kg 16.26 Arginine mg / kg 302.53 Cystine mg / kg 30.19 Methionine mg / kg 32.46 Tryptophan mg / kg 0

Therefore, when a functional ring is manufactured using such a nifa palm phlox, it has an excellent antioxidant ability, and has an anticancer effect through selenium or the like, and gives a beneficial effect to the human body.

The method for producing a functional ring according to the present invention comprises the steps of preparing a nipponia liquor concentrate, preparing a flower bud of nifayja as a powder, mixing the prepared liquid concentrate and a nifana phalaenopsis powder, , Molding the mixed mixture into a circle, applying edible gold powder to the surface of the formed ring, and drying the ring coated with the gold powder.

Hereinafter, the present invention will be described step by step with reference to Fig.

Nipa Preparing a liquid concentrate.

First, prepare a liquid concentrate of NiPhaya. The liquid concentrate is obtained by concentrating the liquid. When a wound is formed on the top of a nipahaya phalaenopsis, and a wounded area is covered with a plastic bag or the like, 500 to 700 g of liquid per one night can be obtained. The liquid is heated at about 60 to 80 ° C for about 2 to 4 hours to be concentrated to have a sugar content of 60 to 80 brix.

This nipah sasa liquid concentrate is dark brown in color and can feel a bitter but strong sweet taste. In addition, as shown in Tables 3 and 4, selenium having various anticancer effects as well as a large amount of polyphenols and various effective ingredients are included, thereby helping the health of the recipient.

Analysis of the components of the nipah palm extract. Inspection items unit test results Inspection items unit test results moisture % 27.91 Goat Mu g / kg 14673.77 Crude protein % 1.25 sulfur mg / kg 469.30 Crude fat % 0.11 manganese mg / kg 4.20 Views min % 5.17 salt mg / kg 4358.02 carbohydrate % 68.56 Total polyphenol mg / kg 1262.67 calorie kcal / 100g 280.23 Crude saponin mg / kg 1407.11 calcium mg / kg 7.89 pH 5.21 sign mg / kg 471.13 Sugar content Brix 76.2 iron mg / kg 46.37 fruit sugar % 8.16 potassium mg / kg 10894.96 glucose % 8.47 magnesium mg / kg 226.85 saccharose % 49.39 Copper mg / kg 1.47 Propionic acid % 0.34 zinc mg / kg 5.48 Acetic acid % 6.33 Selenium Mu g / kg 234.03

The results of composition test of the nipah palm solution concentrate. Inspection items Free amino acid (mg / kg) Phosphoserine 141.68 Taurine 91.67 Phospho ethanol amine 689.59 Aspartic acid 1282.19 Theonine 139.32 Serine 392.93 Glutamic acid 1059.81 Proline 257.69 Glycine 26.45 Alanine 330.94 Citrulline 9.61 alpha -amino-n-butyric acid 1.82 Valine 197.69 Methionine 26.37 Cystathionine 29.66 Isoleucine 99.99 Leucine 68.93 Tyrosine 73.70 Phenylalanine 47.11 β-Alanine 141.26 β-Amino isobutyric acid 57.11 γ-Amino-n-bytyric acid 78.37 Ornithine 23.23 Lysine 156.70 Histidine 34.61 Arginine 210.53

Nipaya The step of preparing the flower bud as a powder.

Separately from the preparation of the above-mentioned liquid concentrate, the flower bud of Nipaya is made into powder. The method comprises the steps of cutting a flower bud of Nipaya, a step of putting the flower bud of the cut Nipaya flower into boiling water, drying the flower bud of the flavored Nipaya flower, pulverizing the dried flower bud of Nipaya flower, .

To describe this in detail, first, a flower bud of a nippi is picked up and cut into a length of 3 to 10 cm and a width of about 1 cm. Then, cut the peduncle into boiling water, that is, water at 100 ° C for 2 to 10 minutes. Then, it is dried so as to have a moisture content of 10% or less, preferably 5 to 10%. At this time, as the drying method, hot air drying, cold air drying, natural drying, or the like can be used. Finally, the dried flower bud is pulverized to about 200 to 300 mesh by a pulverizer.

Here, it is natural that the present invention can be used as it is without removing the buds formed on the flower buds, since the flower buds of Nepalaya are used and the flower buds of Nepalaya contain a large amount of human beneficial ingredients.

Mixing the prepared liquid concentrate and the powder.

Next, the prepared liquid concentrate and powder are mixed at a weight ratio of 1: 0.5 to 1.5, most preferably 1: 1. If the content of the powder is too small, molding into the ring is difficult and the drying time becomes long. If the content of the powder is too large, the formed ring easily collapses due to the lack of adhesiveness. Is most preferable.

And molding the mixed mixture into a circle.

And the mixed mixture is molded into a ring. The method of molding into a ring uses a conventionally known method, that is, a ventilator or the like, and does not limit the size of the ring, that is, the diameter of the ring.

remind Molded Applying the edible gold powder to the surface of the ring.

Next, the edible gold powder is applied to the surface of the formed ring.

The edible gold powder uses commercially available products and does not limit the particle size thereof. In the present invention, the edible gold powder is easily adhered to the surface of the formed ring because of the stickiness of the liquid concentrate. Therefore, it is possible to apply only by spraying the edible gold powder onto the surface of the ring.

The use amount of the edible gold powder is not limited, but it is sufficient that the gold powder is evenly applied on the surface.

The reason for applying the edible gold powder on the surface of the formed ring in the present invention is to enhance the appearance of the edible gold powder to enhance the merchantability and help the heavy metal accumulated in the body to be discharged.

Drying the ring coated with the gold dust.

Finally, the ring coated with the gold dust is dried. At this time, the drying method uses natural drying and cold air drying.

The functional ring of the present invention produced by the above-mentioned method has excellent antioxidant and anti-inflammatory ability, and thus helps the health of the consumer.

The functional ring of the present invention is a health supplement, and its intake amount is not limited, but it is preferable to ingest 1 ring / day of a ring formed with a diameter of 0.7 to 1 cm.

Hereinafter, the present invention will be described in more detail with reference to specific examples.

(Production Example 1)

First, the nipponia palms were picked, cleaned and then cut into 10 cm lengths and 1 cm widths. Then, it was boiled in boiling water at 100 ° C for 3 minutes. Then, the mixture was naturally dried to have a moisture content of 7%, and then pulverized by a pulverizer to prepare a 200-mesh powder.

(Test Example 1)

Evaluation of Antioxidative Capacity of.

The antioxidative capacity of the nifalcaya peduncle prepared in Preparation Example 1 was measured.

(1) Extraction of sample

The ethanol extract of the sample was prepared by adding 95% ethanol of 9 times the amount of the sample (w / v), firstly extracting it with stirring at room temperature for 1 week using an automatic stirrer, and filtering paper (Advantec No. 2, Toyo Roshi Kainshm. , Tokyo, Japan), and concentrated under reduced pressure at 40 ° C in a rotary vacuum evaporator (EYELAA-1000S, Tokyo Rikakikai Co., Tokyo, Japan).

(2) Measurement of DPPH radical scavenging ability

To determine the antioxidant activity, the Biois method was used to examine the radical scavenging effect of DDPH (1,1-diphenyl-2-picryhydrazyl, Sigma-Aldrich Co.). 1 ml of 0.2 mM DPPH was added to 1 ml of the sample solution prepared from 0.625 to 10 mg / ml of each extract, mixed using a vortex mixer, reacted for 30 minutes in a dark room, and absorbance was measured at 517 nm. Then, free radical scavenging activity curves were generated using the following equation, and IC ₅₀ was calculated. As a positive control, ascorbic acid was used.

Radical scavenging activity (%) = {(control Absorbance - Sample Absorbance) / control Absorbance} × 100

(3) Measurement of ABTS radical scavenging ability

ABTS radical scavenging activity was measured by Pellegrin et al. 5 ml of 7 mM ABTS (2,2'-azinobis (3-ethylenbenzothiazoline-6-sulfonate), Sigma-Aldrich Co.) and 88 μl of 140 mM K ₂ S ₂ O ₈ (Sigma-Aldrich Co.) .

The mixture was mixed with absolute ethanol at a ratio of 1:88, and the ABTS solution was prepared so that the absorbance of the control was adjusted to 0.7 ± 0.002 at 734 nm. 1 ml of ABTS solution was added to 50 μl of the sample solution, and the mixture was allowed to stand in a dark room for 2.5 minutes, and the absorbance was measured at 734 nm.

The results are shown in Tables 5 and 6 below.

Results of measurement of DPPH radical scavenging activity according to Test Example 1. Samples Concentration
(mg / ml) Scavenging activity (%) IC ₅₀
(mg.ml) Nipa 0.025
0.125
0.0625
0.03125
0.15625 85.83 + - 0.22
51.52 ± 1.09
26.74 1.51
13.93 ± 2.09
7.82 + - 0.37 0.017 ± 0.00 Blueberries (dried) One
0.5
0.25
0.125
0.0625 60.70 + - 0.47
44.73 + - 0.74
36.62 ± 0.49
30.87 + - 0.41
28.79 + - 0.41 0.627 + - 0.01 Red ginseng (6 years old, dried) One
0.5
0.25
0.125
0.0625 44.89 + - 0.41
37.41 + - 0.41
32.67 + - 0.43
30.27 + - 0.14
28.98 + - 0.43 1.282 + 0.03

The IC ₅₀ value represents the concentration of the extract which reduces the value of the control without the extract by 50%. The smaller the IC ₅₀ value, the higher the antioxidant activity. Therefore, as shown in Table 5, according to DPPH radical scavenging activity measurement results, the antioxidant activity of Nypha palmaxil was about 40 times higher than that of blueberry and about 75 times higher than that of red ginseng.

Results of measurement of ABTS radical scavenging activity according to Test Example 1. Samples Concentration
(mg / ml) Scavenging activity (%) IC ₅₀
(mg.ml) Nipa 0.025
0.125
0.0625
0.03125
0.15625 44.44 + - 0.42
23.28 ± 0.99
11.54 + - 0.94
5.87 ± 0.27
2.50 ± 0.56 0.070 ± 0.00 Blueberries (dried) One
0.5
0.25
0.125
0.0625 17.68 ± 0.51
10.05 + 0.48
5.40 ± 0.17
3.12 ± 0.15
2.08 ± 0.59 2.918 ± 0.13 Red ginseng (6 years old, dried) One
0.5
0.25
0.125
0.0625 11.89 + - 0.54
6.09 ± 0.51
3.02 ± 0.31
1.58 ± 0.56
0.25 0.31 4.131 + 0.24

As shown in Table 6, according to the result of ABTS radical scavenging activity measurement, the antioxidant activity of the Nihonpalaceae was about 42 times higher than that of blueberry and about 59 times higher than that of red ginseng.

(Test Example 2)

Anti - Inflammatory Effects of.

The anti-inflammatory effect of the Nihonpalaceae prepared as in Preparation Example 1 was measured.

IL-1β (interleukin-1beta), IL-6 (interleukin-6, interleukin-6) and TNF-α (tumor necrosis factor-alpha, Or tumor necrosis factor-alpha).

The test method was to investigate whether inflammation was induced by macrophages using LPS (lipopolysaccharide) and the general inflammation index was suppressed when the sample was treated with LPS (lipopolysaccharide). As a positive control, DEX (Dexamethasone) was used as a comparative drug. The sample was prepared by adding a 1: 5 volume ratio of the nifedowana phalaenopsis powder prepared in Preparation Example 1 and water at a temperature of 60 to 80 DEG C for 48 hours to prepare a hot water extract. The extract was freeze- After the preparation, it was diluted to the concentration.

The results are shown in Figs. 2 to 5. Fig.

As can be seen from FIG. 2, Nitrite was significantly increased upon induction of inflammation by LPS, but Nitrite increased due to treatment of NIPHACA.

As can be seen from FIGS. 3, 4 and 5, cytokine was significantly increased upon induction of inflammation induced by LPS, but it was confirmed that the inflammation was alleviated by the treatment of Nephala palmetto.

Therefore, it was judged that the stamen of the nipponeya had an inhibitory effect on inflammatory factors in a concentration-dependent manner and a suppressive effect similar to DEX known as an anti-inflammatory component.

(Example 1)

In the same manner as in Preparation Example 1, a flower bud of NiPhaya was prepared as a powder. Then, the nipahaxa solution concentrate was wounded on the upper part of the phloem of nipaya, which was wrapped in a plastic bag to obtain a solution overnight, followed by concentrating by heating at 70 ° C for 3 hours. At that time, the sugar content was 71brix.

The prepared powder and the liquid concentrate were mixed at a weight ratio of 1: 1, and the mixture was molded into a circle having a diameter of 0.7 cm. Then, the surface of the powder was coated with edible gold powder. And dried in cold air (5 ° C) for 1 hour.

(Test Example 3)

The taste, aroma, appearance, and overall acceptability of the 20 sensory evaluation personnel trained in the rings prepared in Example 1 were evaluated by the 9-point scale method (1: very bad, 9: very good) The average value is shown in Table 1 below. The control was purchased and compared with the commercially available Cheonggukjang.

Results of Test Example 3. flavor Scent Exterior Overall likelihood Example 1 5.8 6.1 6.0 5.9 Control 3.3 3.5 3.3 3.5

As shown in Table 7, it was confirmed that Example 1 of the present invention had higher taste, smell, appearance, and overall acceptability than the control. It was judged that the palatability and flavor of nipaya was felt during ingestion and the degree of preference increased.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the scope of the present invention is not limited to the disclosed exemplary embodiments. It will also be appreciated that many modifications and variations will be apparent to those skilled in the art without departing from the scope of the invention.

Claims

Preparing a nipahi liquid concentrate,
Preparing a flower bud of nifayja as a powder,
Mixing the prepared liquid concentrate and the powder,
Molding the mixed mixture into a circle;
Applying edible gold powder to the surface of the shaped ring,
Drying the ring to which the gold dust is applied,
Wherein the step of preparing the nipahyal liquid concentrate comprises:
Comprising the steps of: obtaining a sap from a palm tree, heating the obtained sap at 60 to 80 DEG C for 2 to 4 hours to obtain a sugar content of 60 to 80 brix,
The step of producing the flower bud of nifayja as a powder comprises:
A step of cutting a flower bud of nipaya,
Placing the cut flower of the nippae in boiling water,
Drying the spikelets of the poached nepalese,
And crushing the dried flower bud of the nippae,
In the step of mixing the prepared liquid concentrate and powder,
The liquid concentrate and the powder are mixed at a weight ratio of 1: 0.5 to 1.5,
A method for producing a functional ring using a nipponja, the method comprising drying the beaked peduncle to a moisture content of 5 to 10%.

delete

The method according to claim 1,
In the step of producing the flower bud of nifayja as a powder,
Wherein the flower bud is produced as a powder together with the flower bud of the nifayja.

7. A functional ring using nipahazatine, which is produced by the method of claim 1 or 6.