KR101651186B1 - Cosmetic Composition - Google Patents

Abstract

The present invention relates to a cosmetic composition comprising at least one oil selected from the group consisting of Cinnamon Bark Oil and Black Pepper Oil. The cosmetic composition according to the present invention can effectively control germs of the skin and promote blood circulation of the skin.

Cinnamon bark oil, pepper oil

Description

[0001] Cosmetic Composition [

The present invention relates to a cosmetic composition comprising at least one oil selected from the group consisting of Cinnamon Bark Oil and Black Pepper Oil.

Microorganisms are living organisms that always exist around us, and there are beneficial microorganisms that help human beings, but harmful microorganisms exist which cause problems such as illness, odor, and aesthetics. In particular, microorganisms exist in the body such as hair, body, hand, and foot due to the external environment, and a large amount of microorganisms exist in pet hair. In addition, microorganisms exist in foods such as vegetables, fruits, fishes, food cooking utensils, tableware or cooking places, and microorganisms exist in toilet rooms and the like. Due to these microorganisms, human life is threatened, and there is a need for an antimicrobial agent to sterilize and clean microorganisms for a safe and hygienic life, and various antibacterial agents have been developed accordingly.

Women's skin is easily aged and experiences blood circulation problems as they age or experience childbirth. As a result, the metabolism ability is lowered, the elasticity of the skin is reduced, and the skin type is changed as well as being easily roughened. In addition, the ozone layer is destroyed externally to increase the content of ultraviolet ray reaching the surface and the environmental pollution is intensified, thereby increasing free radicals and harmful free radicals, thereby decreasing skin thickness, increasing wrinkles and reducing elasticity As well as increased spots, freckles and black blotch will also cause a variety of changes. Therefore, studies on the improvement of skin blood circulation are expected to be continuously carried out, and there is an increasing demand for cosmetics therefor.

The present invention aims at solving the technical problem that has been requested from the past. Specifically, one object of the present invention is to provide a cosmetic composition that exhibits skin antibacterial and skin blood circulation promoting effects.

To this end, one embodiment of the present invention relates to a cosmetic composition comprising at least one oil selected from the group consisting of Cinnamon Bark Oil and Black Pepper Oil.

The cosmetic composition according to the present invention has antibacterial effect through at least one oil selected from the group consisting of cinnamon bark oil and pepper oil, and can promote blood circulation in the skin.

In one embodiment, the composition may comprise both cinnamon bark oil and pepper oil.

The inventors of the present application have found that a cosmetic composition comprising both cinnamon bark oil and pepper oil has a better skin antimicrobial effect than the use of cinnamon bark oil and pepper oil, Skin diseases such as various eczema that are infected can be alleviated and improved.

In addition, it has been confirmed that the cosmetic composition containing both cinnamon bark oil and pepper oil can promote blood circulation in the skin to increase blood flow, compared with using cinnamon bark oil and pepper oil, This can be expected to improve skin temperature and skin elasticity. This can ultimately delay skin aging and prevent or ameliorate all the symptoms of aging to provide anti-aging efficacy.

At this time, the ratio of the cinnamon bark oil and the pepper oil may be any ratio as long as it can achieve the desired skin antibacterial effect and skin blood circulation promoting effect. For example, the ratio may be 1 to 3: 1 to 3, preferably 1 : 1, but is not limited thereto.

The content of the oil in the composition may be, for example, 0.06 to 0.5% by weight based on the total weight of the composition. If the content of the oil is out of the defined range, the anti-inflammation and blood circulation improvement Can not be obtained.

According to the present invention, a cosmetic composition comprising at least one oil selected from the group consisting of cinnamon bark oil and pepper oil can control bacteria in the skin.

In one embodiment, the cosmetic compositions comprising both cinnamon bark oil and pepper oil exhibited particularly excellent skin bacterial control, i.e., antimicrobial effect, when compared to cosmetic compositions comprising the respective oils separately.

The bacterium is not particularly limited as long as it is a microorganism causing a problem in skin function. For example, it may be Staphyococcus aureus (ATCC 6538) and Escherichia coli (ATCC 8739) Bacteria to which the effect can be applied are not limited thereto.

Also, according to the present invention, a cosmetic composition comprising at least one oil selected from the group consisting of cinnamon bark oil and pepper oil can promote blood circulation.

In one embodiment, the cosmetic composition containing both cinnamon bark oil and pepper oil showed excellent blood circulation promoting effect and improved blood circulation when compared with the cosmetic composition containing each oil separately .

The cosmetic composition according to the present invention may be formulated containing a cosmetically or dermatologically acceptable medium or base. It may be any form suitable for the skin, for example, as a solution, a gel, a solid, a paste anhydrous product, an emulsion obtained by dispersing an oil phase in a water phase, a suspension, a microemulsion, a microcapsule, a microgranule, May be provided in the form of an ionic follicle dispersing agent or in the form of a skin, lotion, cream, pack, gel, makeup base, foundation, powder, ointment, spray or conceal stick. These compositions may be prepared according to conventional methods in the art. The composition according to the invention may also be used in the form of a foam or in the form of an aerosol composition further containing a compressed propellant.

The cosmetic composition according to the present invention can be used as a cosmetic composition in the form of a cosmetic composition containing a lipid, an organic solvent, a solubilizer, a thickening agent, a gelling agent, a softening agent, an antioxidant, a suspending agent, a stabilizer, a foaming agent, a fragrance, Such as fillers, emulsifiers, emulsifiers, fillers, sequestering agents, chelating agents, preservatives, vitamins, blocking agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents, lipid vesicles or any other ingredient commonly used in cosmetics May contain adjuvants commonly used in the field of cosmetics or dermatology. Such adjuvants are introduced in amounts commonly used in the cosmetics or dermatological fields.

Hereinafter, the present invention will be described in further detail with reference to the following examples. However, the following examples are for illustrative purposes only and are not intended to limit the scope of the present invention.

[Example 1 and Comparative Examples 1 to 4]

The cosmetic composition was prepared as shown in Table 1 below, and cinnamon bark oil and pepper oil were purchased from Albert Vieille and Charabot, respectively.

[Table 1]

[Experimental Example 1] MIC (Minimal Inhibitory Concentration) measurement of cinnamon bark oil and pepper oil

 <Test Method>

Aspergillus Niger (Aspergillus niger: ATCC 96421), Candida albicans (candida albicans: ATCC 10231), acne bacteria (Propionibacterium acnes: ATCC 6919), Pseudomonas aeruginosa (Pseudomonas Aeruginosa: ATCC 9027), bideumgyun (Pityrosporum ovale: ATCC 12087), Staphylococcus aureus (Staphyococcus aureus: ATCC 6538) and Escherichia coli: The minimum growth inhibitory concentration (Minimal In order to compare the antibacterial activity of the (Escherichia coli ATCC 8739) Inhibitory Concentration (MIC) test "Broth dilution". Cinnamon bark oil and pepper oil were purchased from Charabot and Albert Vieille, respectively.

<MIC test> liquid medium dilution method>

1) Each test strain was used for the test after incubation at 32 ° C for 24 hours using casein soybean digest broth.

2) The test substance was dissolved in the casein soybean digestion liquid medium by concentration.

3) 100 μl of the medium in which the test substance was dissolved was placed in a 96-well plate.

4) Each test strain was inoculated so that the initial number of bacteria was 10 ⁵ to 10 ⁶ / ml.

5) The inoculated plates were incubated in a 32 ° C incubator for 48 hours.

6) Minimal inhibitory concentration (MIC) was measured by turbidity and microscopic observation after incubation. The results are shown in Table 2.

 [Table 2] MIC Result after Treatment of Example 1 (%)

Experimental Example 2: Antimicrobial effect test of a composition containing cinnamon bark oil and pepper oil: Comparison of bactericidal kill rate

The mortality rates of Staphylococcus aureus (ATCC 6538) and Escherichia coli (ATCC 8739) before and after the treatment of Example 1 and Comparative Example 3 were compared for each strain.

1) Each test strain was used for the test after shaking culture at 32 ° C for 24 hours in TSB.

2) The culture (Escherichia coli) was diluted to 10 ^{-4 with} sterilized ionized water so that the inoculum amount was ~ 10 ^-5 .

3) After inoculation of 1 ml of the inoculum with 20 g of sterile ionized water, the number of bacteria was measured (LA) or the number of initial bacteria was measured.

4) The number of bacteria was measured (LA) after 5 minutes and 10 to 120 minutes after inoculation of 10 ml of diluted samples.

The number of bacteria was measured by dilution with 10 ^-2 dilution water. The results are shown in Tables 3 and 4.

[Table 3] Example 1, Comparative Example 3 After treatment, E. coli death rate

[Table 4] After Example 1 and Comparative Example 3 treatment, the staphylococcal killing rate

[Experimental Example 3] Antibacterial effect test of a composition containing cinnamon bark oil and pepper oil: Comparison using a hand plate

Hand hands before and after the treatment of Example 1 and Comparative Examples 1 to 3 were compared on hand plates.

1) The same condition was made as possible by rubbing both hands uncleaned without washing.

2) The cream of Example 1 and Comparative Examples 1 to 3 was applied three times (the amount of coating once was 300 l) and then taken on a hand plate medium.

3) After 1-2 minutes, the dried hands were absorbed and taken on the hand plate medium.

4) After incubation for 2 ~ 3 days in a 32 ℃ incubator, it was observed. The results are shown in Fig.

As shown in FIG. 1, when the cinnamon bark oil and the pepper oil of the present invention are combined, it is possible to obtain an excellent antimicrobial effect on the skin topical bacterium even in a small amount due to their synergistic effect.

[Experimental Example 4] Evaluation of blood circulation promoting effect using LDPI

In order to evaluate the skin circulation promotion effect of the composition containing the cinnamon bark oil and pepper oil of the present invention, the degree of blood circulation in the skin was measured using LDPI (Laser Doppler Perfusion Imager). LDPI is a widely used and widely used device for measuring circulation in the skin. It is a highly sensitive device that can measure not only the velocity and quantity of blood in the capillaries of the skin but also the flow in the small arteries and the parenchyma. to be.

In the temperature and humidity chamber where LDPI was placed, the hands were cleaned with soap, washed, and adjusted for 30 minutes. Initial values were measured in both hands using LDPI. A total of 10 participants (5 males and 5 females) participated in the experiment, and the blood changes were measured at 4 sites per hand and expressed as a mean value.

The cream of Example 1 was applied to the left hand of the subject, and the cream of Comparative Example 2 was applied to the right hand of the subject. After 30 minutes, the cream of Example 1 was applied to the blood of the subject by using LDPI The degree of circulation was measured. The results are shown in Fig.

As shown in FIG. 3, when the cinnamon bark oil and pepper oil of the present invention are used in combination, blood circulation is promoted even with a low aroma due to their synergistic effect.

[Experimental Example 5] Evaluation of blood circulation improving effect in the hand

The hands were soaked with soap in a constant temperature and humidity chamber, and then adjusted for 30 minutes. Initial values were measured using an LDPI and an IR (Infrad) camera for skin temperature measurement. The subjects were 11 women who had cold hands and feet. LDPI was used to measure the initial blood flow of both hands, and before the cold stress was applied (leftmost of FIGS. 4 and 5) and immediately after (0 min; 4 and 5), Example 1 was applied to the left hand of the subject, and cream of Comparative Example 2 was applied to the right hand of the subject for 40 minutes (rightmost in FIGS. 4 and 5) The degree of circulation was measured. The results are shown in FIG. 4 (the right hand of the right examinee of Comparative Example 2) and FIG. 5 (the left hand of the right examinee of Example 1), and the recovery rate against cold stress was calculated according to the following Formula 1, .

[Equation 1] Recovery rate = (after-before) / before * 100 (number of subjects (n) = 4)

(After: temperature after giving cold stress, Before: temperature before cold stress cycle)

As shown in FIG. 4 to FIG. 6, when the cream containing the cinnamon bark oil and pepper oil of the present invention is applied in the case of using only pepper oil, which has been previously shown to have a blood circulation promoting effect, .

Although the present invention has been described in connection with the above-mentioned embodiments, it is possible to make various modifications and variations without departing from the spirit and scope of the present invention. Accordingly, the appended claims are intended to cover such modifications or changes as fall within the scope of the invention.

1 is a photograph showing a result of measuring antibacterial effect using a hand plate of a cosmetic composition according to an embodiment of the present invention;

2 is a photograph showing a result of giving a cold stress to the hand;

FIG. 3 is a photograph showing the result of measuring the blood circulation promoting effect of the cosmetic composition according to one embodiment of the present invention through LDPI (Laser Doppler Perfusion Imager); FIG.

FIG. 4 and FIG. 5 are photographs showing the results of evaluating blood circulation improvement effect of a cosmetic composition according to an embodiment of the present invention through an infrared (IR) camera; FIG.

FIG. 6 is a graph showing the blood circulation improving effect of the cosmetic composition according to an embodiment of the present invention.

Claims (7)

Cinnamon bark oil and black pepper oil, and the weight ratio of the cinnamon bark oil and the pepper oil is 1 to 3: 1 to 3. delete delete The method according to claim 1, Wherein the oil is contained in an amount of 0.06 to 0.5% by weight based on the total weight of the composition. The method according to claim 1, Wherein the composition is a skin antimicrobial composition. 6. The method of claim 5, Wherein the composition exhibits an antibacterial action against Staphylococcus aureus (ATCC 6538) or Escherichia coli (ATCC 8739). The method according to claim 1, Wherein the composition promotes blood circulation.

Images