KR101644604B1 - Toxicity testing device for harmful gas - Google Patents
Toxicity testing device for harmful gas Download PDFInfo
- Publication number
- KR101644604B1 KR101644604B1 KR1020150147457A KR20150147457A KR101644604B1 KR 101644604 B1 KR101644604 B1 KR 101644604B1 KR 1020150147457 A KR1020150147457 A KR 1020150147457A KR 20150147457 A KR20150147457 A KR 20150147457A KR 101644604 B1 KR101644604 B1 KR 101644604B1
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- South Korea
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- test case
- noxious gas
- fan
- test
- case
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/02—Breeding vertebrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L5/00—Gas handling apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
Abstract
Description
The present invention relates to a toxicity test apparatus for toxic gases and a control method thereof, and more particularly to a toxicity test apparatus for toxic gases, which can observe changes in laboratory animals or cells while providing a concentration of harmful gases such as carbon monoxide To a toxicity test apparatus for toxic gases capable of easily maintaining the concentration of harmful gas throughout the space and easily replacing parts of a test apparatus and a control method thereof.
2. Description of the Related Art In general, there are known two methods of inhalation experiment for examining the effect of a drug on a living body by administering a drug to a small laboratory animal such as a rat, a mouse or a guinea pig, .
In the whole body exposure method, an experimental animal is housed in an experimental container, sealed, and the test substance is supplied from one side of the container, and the mixed gas of the residual gas of the test substance and the exhalation gas of the test animal is discharged from the other side.
The non-exposure method is a method for exposing the test substance-containing air to an air-permeable inner tube, a non-exposed nozzle mounted on the inner-air tube, and a gas- And an experimental animal holder attached to an outer tube at a position opposite to the bosom exposing nozzle, and the experimental material from the bosom exposed nozzle is injected into the experimental animal by the inspiration of the experimental animal.
Among them, since the test chamber is large and accommodates a large number of cages therein, it is difficult to observe the appearance of each animal from the outside and requires a large amount of facility cost, Is suitable for exposure experiments using expensive test materials or small test materials because they can be tested at smaller exposure volumes than systemic exposure methods.
On the other hand, in the nasal exposure method, the experimental animals are restrained in the cylindrical holder for a long period of time, thereby giving stress to the experimental animals such as suppression of weight gain, thereby affecting the reliability of the test results. And it is not preferable from the viewpoint of animal welfare.
In order to solve the above-mentioned problems, when a whole body exposure test chamber has been developed, the chamber for whole body exposure test according to the related art has a bottom plate, a side plate rising from the peripheral edge of the bottom plate, A net bottom provided with a space between the bottom plate and the bottom plate in the lower part of the breeding box so as to be accommodated with an experimental animal; An air outlet member attached to the bottom of the breeding box so as to pass through the bottom plate of the breeding box and connected to an exhaust pipe for sucking air in the breeding box, a top plate, an inclined side plate extending downward from the periphery of the top plate, And an opening surrounded by the lower edge of the inclined side plate, and the opening is hermetically joined with the opening of the feeding box, And a feed mechanism member attached to the top plate of the hopper so as to penetrate the top plate and connected to a feed pipe for feeding the gas to be tested in the feeding box.
BACKGROUND ART [0002] The background art of the present invention is disclosed in Korean Patent Registration No. 10-1476635 (entitled "Whole Body Exposure Chamber" and "Whole Body Exposure Test Apparatus Using the same", published on Dec. 29, 2014, entitled "
In the test apparatus according to the related art, since the gas supply mechanism for supplying gas is installed at the upper end and the exhaust port is installed at the lower end, when the amount of supply is not raised above the set value, It is difficult to provide a uniform concentration of gas in the space and it is difficult to carry out a precise test.
In addition, in the test apparatus according to the related art, when a separate circulating apparatus for uniformly maintaining the gas concentration in the entirety of the experimental space is installed, if a failure occurs in the circulating apparatus used for a long period of time, There is a problem that it is difficult to reduce the time required to stop the test.
Therefore, there is a need for improvement.
The present invention can observe changes in laboratory animals or cells while keeping the concentration of harmful gas such as carbon monoxide within the set range, maintain the harmful gas concentration uniform throughout the test space, facilitate the replacement of parts of the test apparatus The present invention also provides a toxicity test apparatus for toxic gases and a control method thereof.
The present invention relates to a semiconductor device comprising a base; A test case installed in the base and having a door member and receiving a test object; A supply pipe connected to the test case to supply noxious gas; A valve installed in the supply pipe and regulating a supply amount of the noxious gas; An environmental case installed on the base to prevent harmful gas lost from the test case from spreading into the room; A sensing unit for measuring a concentration of noxious gas to be filled in the test case or the environmental case and transmitting a concentration signal; And a concentration signal input from the sensing unit. When the concentration of the noxious gas filled in the test case or the environmental case exceeds a predetermined value, a shutoff signal is transmitted to the valve, and noxious gas is discharged from the environmental case to the outside And a control unit for transmitting a driving signal for discharging the driving signal.
The environmental case of the present invention may further include a finishing panel installed on the base so as to face one surface of the test case; A main body coupled to the finishing panel, the main body having a plurality of surfaces to provide a closed space and installed on the base; And a mounting portion for detachably connecting the main body or the finishing panel to the base.
The mounting portion of the present invention may further include: a first sliding groove portion formed in the base; A first rail provided on the finishing panel to be inserted into the first sliding groove; A second sliding groove portion formed on the base to intersect with the first sliding groove portion; And a second rail portion provided in the main body portion to be inserted into the second sliding groove portion.
Further, the present invention may further include a circulation unit for uniformly dispersing noxious gas flowing into the test case throughout the test case, wherein the circulation unit includes: a first fan that press-feeds the noxious gas discharged from the supply pipe to one side; And a second fan that press-feeds the noxious gas discharged from the supply pipe to the other side.
Further, in the test case of the present invention, a service door detachably connected to the circulation part is installed, and the service door is provided with a connection part for detachably connecting the supply pipe to the service door or a connection part for detachably attaching the circulation part to the service door And a replaceable part for connecting the two parts.
Further, the connection part of the present invention may include: a coupling panel installed on the supply pipe; And a guide member slidably inserted into the coupling panel and closely fitting the supply pipe to the coupling hole portion of the service door.
The replacement unit may further include: a guide rail provided on the service door; And a mounting panel slidably coupled along the guide rail and having a through hole through which the first fan and the second fan are installed and which is connected to the supply pipe.
In addition, the service door of the present invention is installed on the upper surface of the test case, and the second fan is installed on an extension extending from the installation panel.
Further, the service door of the present invention is installed on one side of the test case, the first fan is positioned at an upper end of the installation panel, and the second fan is positioned at a lower end of the installation panel .
According to another aspect of the present invention, there is provided a method of testing a test object, comprising the steps of: (a) installing an environmental case for accommodating a test object in a test case and surrounding the test case; (b) supplying noxious gas into the test case when the installation of the environmental case is completed; (c) uniformly distributing the noxious gas supplied to the test case to the test case when noxious gas is supplied to the test case; (d) determining whether the concentration of the noxious gas in the test case exceeds an upper limit value when the circulation unit is driven; (e) blocking the supply of noxious gas to the test case when the noxious gas concentration in the test case exceeds an upper limit value; And (f) determining whether the concentration of the noxious gas in the test case is less than a lower limit value when the noxious gas supply is interrupted in the test case.
The toxic test apparatus for toxic gas according to the present invention and the control method thereof include an environmental case for enclosing a test case in which test objects such as laboratory animals or cells are housed and a noxious gas is supplied, It is possible to prevent the inside from being lost and there is an advantage that the safety of the operator can be achieved.
In addition, the toxic gas toxicity testing apparatus and its control method according to the present invention include a mounting portion for detachably mounting an environmental case on a base on which a test case is installed, and a connection portion for detachably connecting the supply case and the test case, It is possible to easily carry out work such as storage of a test object, replacement of parts, and the like.
In addition, since the toxicity testing apparatus for toxic gases according to the present invention and the control method thereof are provided with the circulation section for evenly distributing the noxious gas supplied into the test case throughout the test case, even if the test case is formed long in the lateral direction, It is possible to uniformly distribute the harmful gas to both ends of the test case and to the upper and lower ends of the test case so that harmful gas evenly contacts the test object accommodated in the test case and the concentration of the harmful gas in the test case is low There is an advantage that an erroneous operation caused by the movement of the test object can be prevented.
In addition, the toxicity testing apparatus for toxic gases and the control method thereof according to the present invention include a service door capable of replacing the circulation unit and a replacement unit detachably connecting the circulation unit to the service door, It is possible to separate the environmental case from the base and to reduce the time and cost required for replacement of the circulation part by the action of the service door and the replacement part and to suppress the test interruption due to the occurrence of the failure of the circulation part There is an advantage.
1 is a perspective view showing a toxicity testing apparatus for noxious gas according to a first embodiment of the present invention.
2 is a flowchart showing a control method of the toxicity testing apparatus for toxic gases according to the first embodiment of the present invention.
3 is a perspective view showing a toxicity testing apparatus for toxic gases according to a second embodiment of the present invention.
4 is an exploded perspective view showing a toxicity test apparatus for toxic gases according to a second embodiment of the present invention.
5 is a perspective view showing a toxicity testing apparatus for toxic gases according to a third embodiment of the present invention.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, an embodiment of a toxicity test apparatus for toxic gases according to the present invention and a control method thereof will be described with reference to the accompanying drawings.
In this process, the thicknesses of the lines and the sizes of the components shown in the drawings may be exaggerated for clarity and convenience of explanation.
In addition, the terms described below are terms defined in consideration of the functions of the present invention, which may vary depending on the intention or custom of the user, the operator.
Therefore, definitions of these terms should be made based on the contents throughout this specification.
FIG. 1 is a perspective view showing a toxicity testing apparatus for toxic gases according to a first embodiment of the present invention, FIG. 2 is a flowchart showing a method of controlling a toxicity testing apparatus for toxic gases according to a first embodiment of the present invention .
1 and 2, the toxicity testing apparatus for toxic gases according to the first embodiment of the present invention comprises a
The test apparatus according to the present embodiment is a device for uniformly supplying carbon monoxide to the inside of the
The present embodiment is also provided with a sensing unit 102 for measuring and transmitting the concentration of carbon monoxide filled in the
Therefore, it is possible to prevent an erroneous operation in which carbon monoxide is supplied more than necessary and it becomes difficult to observe the change of the test object, and it is possible to prevent the erroneous operation in which the concentration of carbon monoxide is supplied below the set range, .
The
The present embodiment further includes a
The
The
The
A control method of the toxicity testing apparatus for harmful gas according to the first embodiment of the present invention will be described as follows.
A method of controlling a toxicity test apparatus for toxic gases according to a first embodiment of the present invention includes the steps of installing an
First, the operator opens the
Thereafter, when the operator operates the control box provided with the
When the supply of carbon monoxide is started, the
When the supply of carbon monoxide is started, the concentration of carbon monoxide is detected by the
When the concentration of carbon monoxide in the
When the concentration signal transmitted from the
It is possible to observe a change in the test object accommodated in the
FIG. 3 is a perspective view illustrating a toxicity testing apparatus for toxic gases according to a second embodiment of the present invention, and FIG. 4 is an exploded perspective view illustrating a toxicity testing apparatus for toxic gases according to a second embodiment of the present invention.
3 and 4, the
A
Therefore, when the worker places the test object in the
The mounting
The first sliding
Accordingly, the first sliding
Thereafter, when the finishing
A sealing member is provided between the
A
The connecting
An
Since the
The replacing
A pair of
Therefore, the first fan (92) and the second fan (94) can be replaced within a short time without interrupting the toxic gas toxicity test, thereby restraining the interruption of the toxic gas toxicity test due to failure of the test apparatus .
The
The
In addition, the
5 is a perspective view showing a toxicity testing apparatus for toxic gases according to a third embodiment of the present invention.
Referring to FIG. 5, a
This embodiment is characterized in that the
The present embodiment is characterized in that the
This makes it possible to observe changes in laboratory animals or cells while keeping the concentration of harmful gases such as carbon monoxide within the set range, to keep the concentration of harmful gas uniform throughout the test space, It is possible to provide a toxicity test apparatus for toxic gases and a control method thereof.
While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims. .
In addition, the toxicity testing apparatus for toxic gas and the control method thereof have been described as an example, but this is merely an illustrative example, and the test apparatus of the present invention and the control method thereof are also applicable to the toxicity testing apparatus for toxic gas and other products Can be used.
Accordingly, the true scope of the present invention should be determined by the following claims.
10: Base 30: Test Case
31: door member 32: discharge hole portion
32a: plug member 34: operation block
34a: display portion 36: cable
36a:
50: environmental case 52:
54: Finishing
54b: ventilation fan 56: supply pipe
58:
58b: motor 70:
72: first sliding groove portion 74: first sliding portion
76: second sliding groove portion 77: second rail portion
78: Step 79: Finishing block
80: connection part 82: engagement panel
82a:
84: guide
86: Service door 88:
90: circulation part 92: first fan
94:
96:
96b:
100: control unit 102: sensing unit
102a:
Claims (10)
A test case installed in the base and having a door member and receiving a test object;
A supply pipe connected to the test case to supply noxious gas;
A valve installed in the supply pipe and regulating a supply amount of the noxious gas;
An environmental case installed on the base to prevent harmful gas lost from the test case from spreading into the room;
A sensing unit for measuring a concentration of noxious gas to be filled in the test case or the environmental case and transmitting a concentration signal; And
A concentration signal input from the sensing unit is received and a shutoff signal is transmitted to the valve when the concentration of the noxious gas filled in the test case or the environmental case exceeds a set value, And a control unit for transmitting a driving signal for discharging,
Further comprising a circulation unit for uniformly dispersing noxious gas flowing into the test case throughout the test case,
The circulation unit includes:
A first fan for feeding the noxious gas discharged from the supply pipe to one side; And
And a second fan for feeding the noxious gas discharged from the supply pipe to the other side,
The second fan is installed in an extension extending to the inside of the test case so as to be spaced apart from the first fan,
A plurality of discharge holes are formed in the test case, and the discharge hole portion is provided with a stopper member for closing a part of the plurality of discharge hole portions to reduce a cross-sectional area of the discharge hole portion,
Wherein the test case is provided with a service door detachably connected to the circulation part and installed to be openable and closable,
Wherein the service door is provided with a connection part for detachably connecting the supply pipe or a replacement part for detachably connecting the circulation part to the service door.
A finish panel installed on the base so as to face one surface of the test case;
A main body coupled to the finishing panel, the main body having a plurality of surfaces to provide a closed space and installed on the base; And
And a mounting portion detachably connecting the main body or the finishing panel to the base.
A first sliding groove formed in the base;
A first rail provided on the finishing panel to be inserted into the first sliding groove;
A second sliding groove portion formed on the base to intersect with the first sliding groove portion; And
And a second rail portion provided in the main body portion to be inserted into the second sliding groove portion.
A coupling panel installed on the supply pipe; And
And a guide member slidably inserted into the joint panel and closely fitting the supply pipe to the joint hole portion of the service door.
A guide rail provided on the service door; And
And an installation panel slidably coupled along the guide rail and having a through hole formed therein for connecting the first fan and the second fan and communicating with the supply pipe.
Wherein the service door is installed on an upper surface of the test case, and the second fan is installed on an extension extending from the installation panel.
Wherein the service door is installed on one side of the test case, the first fan is positioned at an upper end of the installation panel, and the second fan is positioned at a lower end of the installation panel. Device.
(b) supplying noxious gas into the test case when the installation of the environmental case is completed;
(c) uniformly distributing the noxious gas supplied to the test case to the test case when noxious gas is supplied to the test case;
(d) determining whether the concentration of the noxious gas in the test case exceeds an upper limit value when the circulation unit is driven;
(e) blocking the supply of noxious gas to the test case when the noxious gas concentration in the test case exceeds an upper limit value; And
(f) determining whether the concentration of the noxious gas in the test case is less than a lower limit value when the noxious gas supply is interrupted in the test case,
Wherein the step (c) comprises: a circulation part for uniformly dispersing noxious gas introduced into the test case throughout the test case,
The circulation unit includes:
A first fan for feeding the noxious gas discharged from the supply pipe to one side; And
And a second fan for feeding the noxious gas discharged from the supply pipe to the other side,
The second fan is installed in an extension extending to the inside of the test case so as to be spaced apart from the first fan,
A plurality of discharge holes are formed in the test case, and the discharge hole portion is provided with a stopper member for closing a part of the plurality of discharge hole portions to reduce a cross-sectional area of the discharge hole portion,
Wherein the test case is provided with a service door detachably connected to the circulation part and installed to be openable and closable,
Wherein the service door is provided with a connection part for detachably connecting the supply pipe or a replacement part for detachably connecting the circulation part to the service door.
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KR1020150147457A KR101644604B1 (en) | 2015-10-22 | 2015-10-22 | Toxicity testing device for harmful gas |
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KR1020150147457A KR101644604B1 (en) | 2015-10-22 | 2015-10-22 | Toxicity testing device for harmful gas |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110411771A (en) * | 2019-08-01 | 2019-11-05 | 山东省计量科学研究院 | Refrigerator product automatic overflow experimental rig |
CN110595992A (en) * | 2019-10-14 | 2019-12-20 | 重庆阿泰可环境可靠性检测技术有限公司 | Salt spray test device |
KR20210040504A (en) * | 2019-10-04 | 2021-04-14 | 창원대학교 산학협력단 | Chamber for Diagnosis of Chemical Accident Damage |
KR102563930B1 (en) * | 2023-01-02 | 2023-08-04 | 김근홍 | Gas measuring device with a function of automatically removing the test gas |
CN117136857A (en) * | 2023-10-23 | 2023-12-01 | 佳木斯大学 | Sampling device for small animal breath experiment |
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KR101476635B1 (en) * | 2012-05-16 | 2014-12-29 | 시바타 바이오테크노로지 가부시키가이샤 | Whole-body Inhalation Exposure Chamber, and Apparatus Using the Chamber |
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KR101349548B1 (en) * | 2011-12-01 | 2014-01-09 | (주)디지탈솔루션 | A device for killing insects of postharvest fruit against the peach fruit moth by using controlled atmosphere temperature treatment system |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110411771A (en) * | 2019-08-01 | 2019-11-05 | 山东省计量科学研究院 | Refrigerator product automatic overflow experimental rig |
CN110411771B (en) * | 2019-08-01 | 2024-03-26 | 山东省计量科学研究院 | Automatic overflow test device for refrigerator products |
KR20210040504A (en) * | 2019-10-04 | 2021-04-14 | 창원대학교 산학협력단 | Chamber for Diagnosis of Chemical Accident Damage |
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CN110595992A (en) * | 2019-10-14 | 2019-12-20 | 重庆阿泰可环境可靠性检测技术有限公司 | Salt spray test device |
KR102563930B1 (en) * | 2023-01-02 | 2023-08-04 | 김근홍 | Gas measuring device with a function of automatically removing the test gas |
CN117136857A (en) * | 2023-10-23 | 2023-12-01 | 佳木斯大学 | Sampling device for small animal breath experiment |
CN117136857B (en) * | 2023-10-23 | 2024-01-09 | 佳木斯大学 | Sampling device for small animal breath experiment |
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