KR101514470B1 - 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 - Google Patents
리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 Download PDFInfo
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- KR101514470B1 KR101514470B1 KR1020097016904A KR20097016904A KR101514470B1 KR 101514470 B1 KR101514470 B1 KR 101514470B1 KR 1020097016904 A KR1020097016904 A KR 1020097016904A KR 20097016904 A KR20097016904 A KR 20097016904A KR 101514470 B1 KR101514470 B1 KR 101514470B1
- Authority
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- South Korea
- Prior art keywords
- ligand
- metal ion
- hydroxy
- acid
- solid
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/76—Metal complexes of amino carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G99/00—Subject matter not provided for in other groups of this subclass
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyesters Or Polycarbonates (AREA)
- Catalysts (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88838607P | 2007-02-06 | 2007-02-06 | |
| GBGB0702270.0A GB0702270D0 (en) | 2007-02-06 | 2007-02-06 | Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation |
| GB0702270.0 | 2007-02-06 | ||
| US60/888,386 | 2007-02-06 | ||
| PCT/GB2008/000408 WO2008096130A1 (en) | 2007-02-06 | 2008-02-06 | Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147017806A Division KR20140097492A (ko) | 2007-02-06 | 2008-02-06 | 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20090121281A KR20090121281A (ko) | 2009-11-25 |
| KR101514470B1 true KR101514470B1 (ko) | 2015-04-22 |
Family
ID=39204358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097016904A Active KR101514470B1 (ko) | 2007-02-06 | 2008-02-06 | 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8058462B2 (https=) |
| EP (1) | EP2125847B1 (https=) |
| JP (1) | JP5756598B2 (https=) |
| KR (1) | KR101514470B1 (https=) |
| AU (1) | AU2008212653B2 (https=) |
| BR (1) | BRPI0807212B1 (https=) |
| CA (1) | CA2676146C (https=) |
| CY (1) | CY1116590T1 (https=) |
| EA (1) | EA019635B1 (https=) |
| GB (1) | GB2451713B (https=) |
| HR (1) | HRP20150944T1 (https=) |
| IL (1) | IL199901A (https=) |
| MX (1) | MX2009008281A (https=) |
| PL (1) | PL2125847T3 (https=) |
| WO (1) | WO2008096130A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20150944T1 (hr) | 2007-02-06 | 2015-10-09 | Medical Research Council | Materijali poli-okso-hidroksi-metalnih iona modificirani ligandima, njihove uporabe i postupci za njihovu proizvodnju |
| GB0814326D0 (en) * | 2008-08-05 | 2008-09-10 | Medical Res Council | Phosphate binding materials and their uses |
| GB201101299D0 (en) * | 2011-01-25 | 2011-03-09 | Medical Res Council | Oxygen sensors and their uses |
| GB201507002D0 (en) * | 2015-04-24 | 2015-06-10 | Medical Res Council | Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents |
| GB201517893D0 (en) | 2015-10-09 | 2015-11-25 | Medical Res Council | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids |
| WO2017167963A1 (en) * | 2016-03-31 | 2017-10-05 | Medical Research Council | Methods for producing ferric maltol compositions from ligand modified and ligand coated ferric hydroxides |
| WO2017167970A1 (en) | 2016-03-31 | 2017-10-05 | Medical Research Council | Methods for producing ferric maltol compositions from ferrous hydroxides |
| WO2018029247A1 (en) | 2016-08-10 | 2018-02-15 | Medical Research Council | Compositions comprising nanosilica particles and their use in methods of activating t lymphocytes for therapy |
| HUE070809T2 (hu) | 2017-09-11 | 2025-07-28 | Pharmacosmos Holding As | Vaskomplex vegyületek gyógyászati alkalmazásra |
| GB202005054D0 (en) | 2020-04-06 | 2020-05-20 | Nemysis Ltd | Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases |
| US20230338545A1 (en) * | 2020-09-17 | 2023-10-26 | Syracuse University | Complexes of magnesium maltol (3-hydroxy-2-methyl-4h-pyran-4-one) for oral supplementation |
| JP2024529536A (ja) | 2021-08-03 | 2024-08-06 | ファーマコスモス ホールディング エー/エス | コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物 |
| CA3280511A1 (en) | 2024-07-18 | 2026-03-01 | Malian Biologicals Gmbh | Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases and iron supplementation in neurodevelopmental or psychiatric disorder |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003511435A (ja) | 1999-10-12 | 2003-03-25 | ザ ダウ ケミカル カンパニー | 混合金属キレートおよびそれらの製造方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL264270A (https=) * | ||||
| US2575347A (en) * | 1949-07-14 | 1951-11-20 | Interchem Corp | Metallo organic compounds |
| GB959282A (en) * | 1959-08-19 | 1964-05-27 | Hardman & Holden Ltd | Improvements relating to organic aluminium compounds |
| US3076798A (en) * | 1961-02-23 | 1963-02-05 | Hausmann Lab Ltd | Process for preparing a ferric hydroxide polymaltose complex |
| US3679377A (en) * | 1970-02-17 | 1972-07-25 | Union Oil Co | Iron complexes containing aquo,sulfate and hydroxyl ligands |
| US3821192A (en) * | 1971-08-18 | 1974-06-28 | Central Pharmacal Co | Process for preparing an iron-saccharide complex |
| US4162986A (en) * | 1977-06-20 | 1979-07-31 | Mooney Chemicals, Inc. | Oil-soluble high metal content transitional metal organic oxy, hydroxy, complexes |
| US4137359A (en) * | 1977-10-31 | 1979-01-30 | Mooney Chemicals, Inc. | Elastomers with improved metal adhesion |
| DE4239442C2 (de) * | 1992-11-24 | 2001-09-13 | Sebo Gmbh | Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten |
| US20030049284A1 (en) * | 2001-09-05 | 2003-03-13 | Boccio Jose Ruben | Method of increasing the solubility of alphahydrocarboxilic salts, and products obtained by the method |
| EP1434869B1 (en) | 2001-10-08 | 2010-12-15 | Purac Biochem N.V. | Method for preparing calcium gluconate |
| DE60312827T2 (de) * | 2002-01-24 | 2007-12-06 | William Marsh Rice University, Houston | Teilchen aus organischer Säure und FEOOH (Ferroxanen) und von Ferroxanen abgeleitete Keramiken und Keramikmembrane |
| US7994217B2 (en) | 2002-05-02 | 2011-08-09 | Xanodyne Pharmaceuticals, Inc. | Prenatal multivitamin/multimineral supplement |
| GB0211500D0 (en) | 2002-05-18 | 2002-06-26 | Vitra Pharmaceuticals Ltd | Method of forming iron hydroxypyrone compounds |
| DE10249552A1 (de) * | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US6706904B1 (en) | 2002-12-04 | 2004-03-16 | Albion International, Inc. | Dimetalhydroxy malates |
| TWI335218B (en) | 2003-02-19 | 2011-01-01 | Panion & Bf Biotech Inc | Ferric organic compounds, uses thereof and methods of making same |
| US7964568B2 (en) | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
| WO2005094202A2 (en) * | 2004-03-16 | 2005-10-13 | Navinta, Llc | Iron sucrose complexes and method of manufacture thereof |
| US7179939B2 (en) * | 2004-03-16 | 2007-02-20 | Navinta Llc | Sodium ferric gluconate complexes and method of manufacture thereof |
| ZA200702421B (en) | 2004-10-08 | 2008-09-25 | Unilever Plc | Iron complex for use in the treatment and/or prevention of nutritional disorders |
| DE202005014332U1 (de) | 2005-09-09 | 2006-01-19 | Institut für Oberflächenmodifizierung e.V. | Metallorganisches Nanopulver |
| HRP20150944T1 (hr) | 2007-02-06 | 2015-10-09 | Medical Research Council | Materijali poli-okso-hidroksi-metalnih iona modificirani ligandima, njihove uporabe i postupci za njihovu proizvodnju |
| TWI592159B (zh) | 2007-11-16 | 2017-07-21 | 威佛(國際)股份有限公司 | 藥學組成物 |
| GB0814326D0 (en) * | 2008-08-05 | 2008-09-10 | Medical Res Council | Phosphate binding materials and their uses |
-
2008
- 2008-02-06 HR HRP20150944TT patent/HRP20150944T1/hr unknown
- 2008-02-06 US US12/026,861 patent/US8058462B2/en active Active
- 2008-02-06 EA EA200970718A patent/EA019635B1/ru unknown
- 2008-02-06 JP JP2009548736A patent/JP5756598B2/ja active Active
- 2008-02-06 WO PCT/GB2008/000408 patent/WO2008096130A1/en not_active Ceased
- 2008-02-06 EP EP08709331.6A patent/EP2125847B1/en active Active
- 2008-02-06 KR KR1020097016904A patent/KR101514470B1/ko active Active
- 2008-02-06 AU AU2008212653A patent/AU2008212653B2/en active Active
- 2008-02-06 GB GB0802214A patent/GB2451713B/en active Active
- 2008-02-06 PL PL08709331T patent/PL2125847T3/pl unknown
- 2008-02-06 CA CA2676146A patent/CA2676146C/en active Active
- 2008-02-06 BR BRPI0807212-4A patent/BRPI0807212B1/pt active IP Right Grant
- 2008-02-06 MX MX2009008281A patent/MX2009008281A/es active IP Right Grant
-
2009
- 2009-07-16 IL IL199901A patent/IL199901A/en active IP Right Grant
-
2015
- 2015-08-10 CY CY20151100694T patent/CY1116590T1/el unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003511435A (ja) | 1999-10-12 | 2003-03-25 | ザ ダウ ケミカル カンパニー | 混合金属キレートおよびそれらの製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL199901A0 (en) | 2010-04-15 |
| PL2125847T3 (pl) | 2015-12-31 |
| WO2008096130A1 (en) | 2008-08-14 |
| CA2676146A1 (en) | 2008-08-14 |
| AU2008212653A1 (en) | 2008-08-14 |
| AU2008212653B2 (en) | 2012-05-24 |
| EA200970718A1 (ru) | 2010-02-26 |
| BRPI0807212B1 (pt) | 2022-01-11 |
| IL199901A (en) | 2014-11-30 |
| BRPI0807212A2 (pt) | 2014-06-17 |
| EA019635B1 (ru) | 2014-05-30 |
| US8058462B2 (en) | 2011-11-15 |
| JP5756598B2 (ja) | 2015-07-29 |
| GB0802214D0 (en) | 2008-03-12 |
| JP2010520856A (ja) | 2010-06-17 |
| EP2125847B1 (en) | 2015-06-17 |
| US20080188555A1 (en) | 2008-08-07 |
| CA2676146C (en) | 2016-08-09 |
| KR20090121281A (ko) | 2009-11-25 |
| HK1138598A1 (en) | 2010-08-27 |
| GB2451713B (en) | 2009-12-16 |
| MX2009008281A (es) | 2009-08-25 |
| GB2451713A (en) | 2009-02-11 |
| HRP20150944T1 (hr) | 2015-10-09 |
| CY1116590T1 (el) | 2017-03-15 |
| EP2125847A1 (en) | 2009-12-02 |
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| KR20140097492A (ko) | 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 | |
| US7943664B2 (en) | Phosphate binding materials and their uses | |
| US11684572B2 (en) | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids and related compositions and uses | |
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