KR101514470B1 - 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 - Google Patents

리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 Download PDF

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KR101514470B1
KR101514470B1 KR1020097016904A KR20097016904A KR101514470B1 KR 101514470 B1 KR101514470 B1 KR 101514470B1 KR 1020097016904 A KR1020097016904 A KR 1020097016904A KR 20097016904 A KR20097016904 A KR 20097016904A KR 101514470 B1 KR101514470 B1 KR 101514470B1
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ligand
metal ion
hydroxy
acid
solid
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KR20090121281A (ko
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조나단 조셉 파웰
실뱅 프랑소와즈 알린 부루가라버
누노 조지 로드리게스 파리아
도라 이자벨 아마랄 페레이라
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메디칼 리서취 카운실
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/295Iron group metal compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/76Metal complexes of amino carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02Iron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02Iron compounds
    • C07F15/025Iron compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07GCOMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G99/00Subject matter not provided for in other groups of this subclass

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Catalysts (AREA)
KR1020097016904A 2007-02-06 2008-02-06 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 Active KR101514470B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US88838607P 2007-02-06 2007-02-06
GBGB0702270.0A GB0702270D0 (en) 2007-02-06 2007-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation
GB0702270.0 2007-02-06
US60/888,386 2007-02-06
PCT/GB2008/000408 WO2008096130A1 (en) 2007-02-06 2008-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020147017806A Division KR20140097492A (ko) 2007-02-06 2008-02-06 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법

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KR20090121281A KR20090121281A (ko) 2009-11-25
KR101514470B1 true KR101514470B1 (ko) 2015-04-22

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US (1) US8058462B2 (https=)
EP (1) EP2125847B1 (https=)
JP (1) JP5756598B2 (https=)
KR (1) KR101514470B1 (https=)
AU (1) AU2008212653B2 (https=)
BR (1) BRPI0807212B1 (https=)
CA (1) CA2676146C (https=)
CY (1) CY1116590T1 (https=)
EA (1) EA019635B1 (https=)
GB (1) GB2451713B (https=)
HR (1) HRP20150944T1 (https=)
IL (1) IL199901A (https=)
MX (1) MX2009008281A (https=)
PL (1) PL2125847T3 (https=)
WO (1) WO2008096130A1 (https=)

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HRP20150944T1 (hr) 2007-02-06 2015-10-09 Medical Research Council Materijali poli-okso-hidroksi-metalnih iona modificirani ligandima, njihove uporabe i postupci za njihovu proizvodnju
GB0814326D0 (en) * 2008-08-05 2008-09-10 Medical Res Council Phosphate binding materials and their uses
GB201101299D0 (en) * 2011-01-25 2011-03-09 Medical Res Council Oxygen sensors and their uses
GB201507002D0 (en) * 2015-04-24 2015-06-10 Medical Res Council Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents
GB201517893D0 (en) 2015-10-09 2015-11-25 Medical Res Council Methods for producing carboxylate ligand modified ferric iron hydroxide colloids
WO2017167963A1 (en) * 2016-03-31 2017-10-05 Medical Research Council Methods for producing ferric maltol compositions from ligand modified and ligand coated ferric hydroxides
WO2017167970A1 (en) 2016-03-31 2017-10-05 Medical Research Council Methods for producing ferric maltol compositions from ferrous hydroxides
WO2018029247A1 (en) 2016-08-10 2018-02-15 Medical Research Council Compositions comprising nanosilica particles and their use in methods of activating t lymphocytes for therapy
HUE070809T2 (hu) 2017-09-11 2025-07-28 Pharmacosmos Holding As Vaskomplex vegyületek gyógyászati alkalmazásra
GB202005054D0 (en) 2020-04-06 2020-05-20 Nemysis Ltd Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases
US20230338545A1 (en) * 2020-09-17 2023-10-26 Syracuse University Complexes of magnesium maltol (3-hydroxy-2-methyl-4h-pyran-4-one) for oral supplementation
JP2024529536A (ja) 2021-08-03 2024-08-06 ファーマコスモス ホールディング エー/エス コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物
CA3280511A1 (en) 2024-07-18 2026-03-01 Malian Biologicals Gmbh Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases and iron supplementation in neurodevelopmental or psychiatric disorder

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IL199901A0 (en) 2010-04-15
PL2125847T3 (pl) 2015-12-31
WO2008096130A1 (en) 2008-08-14
CA2676146A1 (en) 2008-08-14
AU2008212653A1 (en) 2008-08-14
AU2008212653B2 (en) 2012-05-24
EA200970718A1 (ru) 2010-02-26
BRPI0807212B1 (pt) 2022-01-11
IL199901A (en) 2014-11-30
BRPI0807212A2 (pt) 2014-06-17
EA019635B1 (ru) 2014-05-30
US8058462B2 (en) 2011-11-15
JP5756598B2 (ja) 2015-07-29
GB0802214D0 (en) 2008-03-12
JP2010520856A (ja) 2010-06-17
EP2125847B1 (en) 2015-06-17
US20080188555A1 (en) 2008-08-07
CA2676146C (en) 2016-08-09
KR20090121281A (ko) 2009-11-25
HK1138598A1 (en) 2010-08-27
GB2451713B (en) 2009-12-16
MX2009008281A (es) 2009-08-25
GB2451713A (en) 2009-02-11
HRP20150944T1 (hr) 2015-10-09
CY1116590T1 (el) 2017-03-15
EP2125847A1 (en) 2009-12-02

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