KR101514470B1 - 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 - Google Patents

리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 Download PDF

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KR101514470B1
KR101514470B1 KR1020097016904A KR20097016904A KR101514470B1 KR 101514470 B1 KR101514470 B1 KR 101514470B1 KR 1020097016904 A KR1020097016904 A KR 1020097016904A KR 20097016904 A KR20097016904 A KR 20097016904A KR 101514470 B1 KR101514470 B1 KR 101514470B1
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ligand
metal ion
hydroxy
acid
solid
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KR20090121281A (ko
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조나단 조셉 파웰
실뱅 프랑소와즈 알린 부루가라버
누노 조지 로드리게스 파리아
도라 이자벨 아마랄 페레이라
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메디칼 리서취 카운실
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/76—Metal complexes of amino carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G99/00—Subject matter not provided for in other groups of this subclass

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Catalysts (AREA)
KR1020097016904A 2007-02-06 2008-02-06 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법 Active KR101514470B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US88838607P 2007-02-06 2007-02-06
US60/888,386 2007-02-06
GBGB0702270.0A GB0702270D0 (en) 2007-02-06 2007-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation
GB0702270.0 2007-02-06
PCT/GB2008/000408 WO2008096130A1 (en) 2007-02-06 2008-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020147017806A Division KR20140097492A (ko) 2007-02-06 2008-02-06 리간드 개질 폴리 옥소-히드록시 금속 이온 물질, 이의 용도 및 이의 제조 방법

Publications (2)

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KR20090121281A KR20090121281A (ko) 2009-11-25
KR101514470B1 true KR101514470B1 (ko) 2015-04-22

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US (1) US8058462B2 (https=)
EP (1) EP2125847B1 (https=)
JP (1) JP5756598B2 (https=)
KR (1) KR101514470B1 (https=)
AU (1) AU2008212653B2 (https=)
BR (1) BRPI0807212B1 (https=)
CA (1) CA2676146C (https=)
CY (1) CY1116590T1 (https=)
EA (1) EA019635B1 (https=)
GB (1) GB2451713B (https=)
HR (1) HRP20150944T1 (https=)
IL (1) IL199901A (https=)
MX (1) MX2009008281A (https=)
PL (1) PL2125847T3 (https=)
WO (1) WO2008096130A1 (https=)

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JP5756598B2 (ja) 2007-02-06 2015-07-29 メディカル リサーチ カウンシル リガンド修飾ポリオキソヒドロキシ金属イオン物質、それらの使用およびそれらの調製方法
GB0814326D0 (en) * 2008-08-05 2008-09-10 Medical Res Council Phosphate binding materials and their uses
GB201101299D0 (en) 2011-01-25 2011-03-09 Medical Res Council Oxygen sensors and their uses
GB201507002D0 (en) * 2015-04-24 2015-06-10 Medical Res Council Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents
GB201517893D0 (en) * 2015-10-09 2015-11-25 Medical Res Council Methods for producing carboxylate ligand modified ferric iron hydroxide colloids
US11267836B2 (en) * 2016-03-31 2022-03-08 Shield TX (UK) Limited Methods for producing ferric maltol compositions from ligand modified and ligand coated ferric hydroxides
US10508094B2 (en) 2016-03-31 2019-12-17 Shield TX (UK) Limited Methods for producing ferric maltol compositions from ferrous hydroxides
JP7510254B2 (ja) 2016-08-10 2024-07-03 ユナイテッド キングダム リサーチ アンド イノベーション ナノシリカ粒子を含む組成物および療法のためにｔリンパ球を活性化する方法におけるそれらの使用
AU2018328052C1 (en) 2017-09-11 2025-12-18 Pharmacosmos Holding A/S Iron complex compounds for therapeutic use
GB202005054D0 (en) 2020-04-06 2020-05-20 Nemysis Ltd Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases
WO2022061065A1 (en) * 2020-09-17 2022-03-24 Doyle Robert P Complexes of magnesium maltol (3-hydroxy-2-methyl-4h-pyran-4-one) for oral supplementation
US20260108551A1 (en) 2021-08-03 2026-04-23 Pharmacosmos Holding A/S Iron complex compounds for subcutaneous use in therapy of iron deficiency in companion animals
WO2026017897A1 (en) 2024-07-18 2026-01-22 Malian Biologicals Gmbh Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases

Citations (1)

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JP2003511435A (ja) 1999-10-12 2003-03-25 ザ ダウ ケミカル カンパニー 混合金属キレートおよびそれらの製造方法

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US3821192A (en) 1971-08-18 1974-06-28 Central Pharmacal Co Process for preparing an iron-saccharide complex
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DE4239442C2 (de) 1992-11-24 2001-09-13 Sebo Gmbh Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten
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IL199901A0 (en) 2010-04-15
AU2008212653B2 (en) 2012-05-24
US8058462B2 (en) 2011-11-15
EA019635B1 (ru) 2014-05-30
CA2676146C (en) 2016-08-09
CA2676146A1 (en) 2008-08-14
GB2451713A (en) 2009-02-11
BRPI0807212A2 (pt) 2014-06-17
HK1138598A1 (en) 2010-08-27
IL199901A (en) 2014-11-30
PL2125847T3 (pl) 2015-12-31
GB2451713B (en) 2009-12-16
CY1116590T1 (el) 2017-03-15
MX2009008281A (es) 2009-08-25
EP2125847B1 (en) 2015-06-17
US20080188555A1 (en) 2008-08-07
JP5756598B2 (ja) 2015-07-29
JP2010520856A (ja) 2010-06-17
KR20090121281A (ko) 2009-11-25
EP2125847A1 (en) 2009-12-02
BRPI0807212B1 (pt) 2022-01-11
GB0802214D0 (en) 2008-03-12
EA200970718A1 (ru) 2010-02-26
HRP20150944T1 (hr) 2015-10-09
WO2008096130A1 (en) 2008-08-14
AU2008212653A1 (en) 2008-08-14

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