KR101454287B1 - Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신 - Google Patents

Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신 Download PDF

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KR101454287B1
KR101454287B1 KR1020097010056A KR20097010056A KR101454287B1 KR 101454287 B1 KR101454287 B1 KR 101454287B1 KR 1020097010056 A KR1020097010056 A KR 1020097010056A KR 20097010056 A KR20097010056 A KR 20097010056A KR 101454287 B1 KR101454287 B1 KR 101454287B1
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KR20090083378A (ko
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토모아키 후지오카
유스케 나카무라
타쿠야 츠노다
류지 오사와
미도리 시다
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온코세라피 사이언스 가부시키가이샤
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KR1020097010056A 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신 Active KR101454287B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85257506P 2006-10-17 2006-10-17
US60/852,575 2006-10-17
PCT/JP2007/001122 WO2008047473A1 (en) 2006-10-17 2007-10-16 Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides

Related Child Applications (1)

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KR1020147011020A Division KR101493773B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신

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KR20090083378A KR20090083378A (ko) 2009-08-03
KR101454287B1 true KR101454287B1 (ko) 2014-11-04

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KR1020097010056A Active KR101454287B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신
KR1020147022451A Active KR101543622B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신
KR1020157000123A Active KR101527473B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신
KR1020147011020A Active KR101493773B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신

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KR1020147022451A Active KR101543622B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신
KR1020157000123A Active KR101527473B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신
KR1020147011020A Active KR101493773B1 (ko) 2006-10-17 2007-10-16 Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신

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EP (7) EP2695895A1 (enExample)
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CN (5) CN102850435B (enExample)
AU (1) AU2007311395B2 (enExample)
BR (1) BRPI0717651A2 (enExample)
CA (2) CA2667030C (enExample)
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MX (1) MX2009004147A (enExample)
PL (1) PL2091965T3 (enExample)
PT (1) PT2091965E (enExample)
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Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2011885B1 (en) 2005-02-10 2015-04-22 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
CA2696591C (en) * 2007-08-20 2016-10-11 Oncotherapy Science, Inc. Cdh3 peptide and medicinal agent comprising the same
JP5640263B2 (ja) * 2008-08-28 2014-12-17 オンコセラピー・サイエンス株式会社 Depdc1ポリペプチドを使用した膀胱癌の治療または予防のための方法
KR20110134446A (ko) * 2009-03-04 2011-12-14 온코세라피 사이언스 가부시키가이샤 Vangl1 펩티드 및 이를 포함한 백신
WO2012032763A1 (en) * 2010-09-07 2012-03-15 Oncotherapy Science, Inc. Vangl1 peptides and vaccines including the same
MX350220B (es) 2011-08-12 2017-08-30 Oncotherapy Science Inc Peptidos de mphosph1 y vacunas que incluyen los mismos.
JP2013058294A (ja) * 2011-09-09 2013-03-28 Toshiba Corp 磁気記録媒体及び磁気記録媒体の製造方法
RU2746407C1 (ru) 2012-02-23 2021-04-13 Стейдж Селл Терапеутикс Гмбх Хроматографическое выделение клеток и других сложных биологических материалов
KR20140138900A (ko) 2012-03-09 2014-12-04 온코세라피 사이언스 가부시키가이샤 펩티드를 포함한 의약 조성물
JP6041297B2 (ja) * 2012-08-24 2016-12-07 国立大学法人山口大学 犬リンパ腫の診断方法及び診断キット
MY177482A (en) * 2013-03-13 2020-09-16 Zhong Li Microvesicle and method for producing the same
MY184699A (en) 2014-04-16 2021-04-18 Juno Therapeutics Gmbh Methods, kits and apparatus for expanding a population of cells
DK3205661T3 (da) * 2014-10-07 2021-08-02 Cytlimic Inc Hsp70-afledt immunitetsinducerende peptid
JP6781508B2 (ja) 2014-11-18 2020-11-04 塩野義製薬株式会社 安定化されたペプチド組成物
CN107428815B (zh) 2015-03-09 2021-07-09 Cytlimic公司 源于gpc3的肽、使用其的用于治疗或预防癌症的医药组合物、免疫诱导剂、及抗原呈递细胞的制造方法
DK3281641T3 (da) 2015-04-07 2021-01-18 Cytlimic Inc Adjuvans til cancervacciner
RU2765574C2 (ru) * 2015-08-12 2022-02-01 Онкотерапи Сайенс, Инк. Пептид, полученный из depdc1, и содержащая его вакцина
SG11201802286PA (en) 2015-10-08 2018-04-27 Oncotherapy Science Inc Mphosph1-derived peptide, and vaccine including same
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
CN108474002B (zh) 2015-10-22 2023-05-23 朱诺治疗学有限公司 用于转导的方法、反应剂盒、反应剂和设备
MA45488A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés, kits et appareil de culture de cellules
WO2018070069A1 (ja) 2016-10-11 2018-04-19 サイトリミック株式会社 医薬
WO2018092755A1 (en) * 2016-11-18 2018-05-24 Oncotherapy Science, Inc. Mphosph1 epitope peptides for th1 cells and vaccines containing the same
TW201831502A (zh) * 2016-11-18 2018-09-01 日商腫瘤療法 科學股份有限公司 對於th1細胞的depdc1抗原決定位胜肽及包含其之疫苗
WO2018094569A1 (zh) * 2016-11-22 2018-05-31 深圳华大基因研究院 多肽及其应用
HUE058717T2 (hu) 2017-01-25 2022-09-28 Ose Immunotherapeutics Eljárás egy stabil emulzió elõállítására peptid szállításához
SG11201909931PA (en) 2017-04-27 2019-11-28 Juno Therapeutics Gmbh Oligomeric particle reagents and methods of use thereof
PT3652606T (pt) * 2017-07-12 2023-03-16 Nouscom Ag Vacina universal baseada em neoantigénios tumorais partilhados para prevenção e tratamento de cancros com microssatélites instáveis (msi)
AU2018384824B2 (en) 2017-12-13 2022-08-04 Inovio Pharmaceuticals, Inc. Cancer vaccines targeting LEMD1 and uses thereof
CN109932510B (zh) * 2017-12-18 2022-07-12 天津云检医学检验所有限公司 一种宫颈癌生物标志物及其检测试剂盒
CN112142824B (zh) * 2019-06-27 2022-03-11 深圳市东贵博康生化科技有限公司 具有诱导细胞毒性t淋巴细胞能力的多肽及其应用
WO2021060343A1 (ja) * 2019-09-24 2021-04-01 オンコセラピー・サイエンス株式会社 Urlc10由来ペプチドまたはdepdc1由来ペプチドを認識するヒトt細胞が発現するt細胞受容体

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006085684A2 (en) * 2005-02-10 2006-08-17 Oncotherapy Science, Inc. Method of diagnosing bladder cancer

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
CZ42794A3 (en) 1991-08-26 1994-11-16 Cytel Corp Hla-re-stringed ctl epitopes of hepatitis b virus
RU94038427A (ru) * 1991-08-26 1996-10-20 Сайтел Корпорейшн (US) Пептиды, конъюгаты, фармацевтические композиции, способы лечения, способ идентификации
NZ263373A (en) * 1993-03-11 1997-05-26 Univ Southern California Monoclonal antibodies and use against immunoinfective cluster viruses
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5804566A (en) 1993-08-26 1998-09-08 The Regents Of The University Of California Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides
US5739118A (en) 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
US5736524A (en) 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
US5922687A (en) 1995-05-04 1999-07-13 Board Of Trustees Of The Leland Stanford Junior University Intracellular delivery of nucleic acids using pressure
AU6632496A (en) 1995-08-03 1997-03-05 Rijksuniversiteit Te Leiden Cell derived antigen presenting vesicles
US5853719A (en) 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
JP2000516090A (ja) 1996-07-26 2000-12-05 スローン―ケッタリング インスティチュート フォー キャンサー リサーチ 遺伝子的免疫化のための方法と試薬
FR2766205B1 (fr) 1997-07-16 2002-08-30 Inst Nat Sante Rech Med Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
US7001999B1 (en) * 1998-04-15 2006-02-21 Ludwig Institute For Cancer Research Tumor associated nucleic acids and uses therefor
BR9914116A (pt) * 1998-09-30 2002-01-15 Corixa Corp Composições e métodos para imunoterapia especìfica de wt1
US20050123938A1 (en) 1999-01-06 2005-06-09 Chondrogene Limited Method for the detection of osteoarthritis related gene transcripts in blood
US20040241726A1 (en) * 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of allergies related gene transcripts in blood
US6291663B1 (en) * 1999-03-03 2001-09-18 Board Of Trustees Of The University Of Arkansas TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma
US7030215B2 (en) * 1999-03-24 2006-04-18 Sangamo Biosciences, Inc. Position dependent recognition of GNN nucleotide triplets by zinc fingers
JP2003518364A (ja) * 1999-05-28 2003-06-10 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ 乳癌、胃癌および前立腺癌関連抗原ならびにそれらの使用
US20030166526A1 (en) 2000-08-22 2003-09-04 Challita-Eid Pia M. Nucleic acid and corresponding protein named 158P1H4 useful in the treatment and detection of bladder and other cancers
CA2425827A1 (en) 2000-10-12 2002-04-18 Hyseq, Inc. Novel nucleic acids and polypeptides
EP1911461B1 (en) 2000-10-19 2011-12-07 Epimmune Inc. HLA class I and II binding peptides and their uses
WO2002046416A2 (en) 2000-12-04 2002-06-13 Argonex Pharmaceuticals Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US7919467B2 (en) * 2000-12-04 2011-04-05 Immunotope, Inc. Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
KR20040077928A (ko) * 2002-01-31 2004-09-07 와이어쓰 아그레카나제 분자
AU2003222103A1 (en) 2002-03-28 2003-10-13 Idec Pharmaceuticals Corporation Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US20060024692A1 (en) * 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
WO2005007090A2 (en) 2003-07-03 2005-01-27 President And Fellows Of Harvard College Inhibitors of the map kinase pathway
CA2580412A1 (en) 2004-09-13 2006-03-23 Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services Compositions comprising t cell receptors and methods of use thereof
JP2006302684A (ja) 2005-04-21 2006-11-02 D D K Ltd カードコネクタ
WO2007013665A2 (en) 2005-07-27 2007-02-01 Oncotherapy Science, Inc. Method of diagnosing small cell lung cancer
KR101130597B1 (ko) 2005-09-13 2012-04-02 다카라 바이오 가부시키가이샤 T 세포 리셉터 및 그 리셉터를 코드하는 핵산
US20070099251A1 (en) * 2005-10-17 2007-05-03 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
TWM336439U (en) * 2008-02-14 2008-07-11 Optivision Technology Inc Diffuser capable of light condensing
JP5640263B2 (ja) * 2008-08-28 2014-12-17 オンコセラピー・サイエンス株式会社 Depdc1ポリペプチドを使用した膀胱癌の治療または予防のための方法
MX350220B (es) 2011-08-12 2017-08-30 Oncotherapy Science Inc Peptidos de mphosph1 y vacunas que incluyen los mismos.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006085684A2 (en) * 2005-02-10 2006-08-17 Oncotherapy Science, Inc. Method of diagnosing bladder cancer

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