KR101428123B1 - 4-아미노-피리미딘의 합성 - Google Patents

4-아미노-피리미딘의 합성 Download PDF

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Publication number
KR101428123B1
KR101428123B1 KR1020097014982A KR20097014982A KR101428123B1 KR 101428123 B1 KR101428123 B1 KR 101428123B1 KR 1020097014982 A KR1020097014982 A KR 1020097014982A KR 20097014982 A KR20097014982 A KR 20097014982A KR 101428123 B1 KR101428123 B1 KR 101428123B1
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South Korea
Prior art keywords
salt
solvent
mixture
acetamidine
formyl
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KR1020097014982A
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English (en)
Korean (ko)
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KR20090101254A (ko
Inventor
베르너 본라쓰
랄프 하에르터
레인하르트 카르게
울라 레티노와
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디에스엠 아이피 어셋츠 비.브이.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020097014982A 2007-01-19 2008-01-17 4-아미노-피리미딘의 합성 Active KR101428123B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07001136.6 2007-01-19
EP20070001136 EP1972620A1 (en) 2007-01-19 2007-01-19 Synthesis of 4-amino-pyrimidines
PCT/EP2008/000320 WO2008087021A1 (en) 2007-01-19 2008-01-17 Synthesis of 4-amino-pyrimidines

Publications (2)

Publication Number Publication Date
KR20090101254A KR20090101254A (ko) 2009-09-24
KR101428123B1 true KR101428123B1 (ko) 2014-08-07

Family

ID=38224299

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097014982A Active KR101428123B1 (ko) 2007-01-19 2008-01-17 4-아미노-피리미딘의 합성

Country Status (6)

Country Link
US (1) US8198443B2 (OSRAM)
EP (2) EP1972620A1 (OSRAM)
JP (1) JP5289331B2 (OSRAM)
KR (1) KR101428123B1 (OSRAM)
CN (1) CN101583604B (OSRAM)
WO (1) WO2008087021A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103420918B (zh) * 2013-07-22 2015-04-22 新发药业有限公司 维生素b1关键中间体2-甲基-4-氨基-5-氨基甲基嘧啶的简便制备方法
CN103435556B (zh) * 2013-08-26 2014-11-26 新发药业有限公司 维生素b1中间体2-甲基-4-氨基-5-氨基甲基嘧啶的合成方法
CN107602482A (zh) * 2017-09-05 2018-01-19 常州大学 一种2‑甲基‑4‑氨基‑5‑(甲酰氨甲基)嘧啶水解工艺
CN107602481A (zh) * 2017-09-05 2018-01-19 常州大学 一种2‑甲基‑4‑氨基‑5‑(甲酰氨甲基)嘧啶水解工艺
CN113252829B (zh) * 2021-05-07 2023-09-22 镇江高等职业技术学校 一种灌溉水中盐酸乙脒的测定方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3511273A1 (de) * 1985-03-28 1986-10-09 Basf Ag, 6700 Ludwigshafen Verbessertes verfahren zur herstellung von 2-methyl-4-amino-5-aminomethyl-pyrimidin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789815A (fr) * 1970-03-27 1973-04-06 Stauffer Chemical Co Vinylphosphonates copolycondenses et leur utilisation comme agents retardant l'inflammation
JPS5518702B2 (OSRAM) * 1972-05-12 1980-05-21
DE3431270A1 (de) * 1984-08-25 1986-03-06 Basf Ag, 6700 Ludwigshafen Alpha-(o-chlorphenyl)-aminomethylen-beta-formylaminopropionitril, verfahren zu seiner herstellung sowie verwendung zur herstellung von 2-methyl-4-amino-5-formylaminomethylpyrimidin
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
US4942085A (en) * 1989-01-23 1990-07-17 American Cyanamid Company Method of manufacturing a sag-resistant bonded particulate article
US5140047A (en) * 1991-05-03 1992-08-18 Smithkline Beecham Corporation Lipoxygenase inhibitors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3511273A1 (de) * 1985-03-28 1986-10-09 Basf Ag, 6700 Ludwigshafen Verbessertes verfahren zur herstellung von 2-methyl-4-amino-5-aminomethyl-pyrimidin

Also Published As

Publication number Publication date
JP2010516644A (ja) 2010-05-20
EP2102172B1 (en) 2015-08-12
US8198443B2 (en) 2012-06-12
JP5289331B2 (ja) 2013-09-11
US20100016591A1 (en) 2010-01-21
KR20090101254A (ko) 2009-09-24
CN101583604B (zh) 2013-03-06
EP2102172A1 (en) 2009-09-23
CN101583604A (zh) 2009-11-18
WO2008087021A1 (en) 2008-07-24
EP1972620A1 (en) 2008-09-24

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