KR101205655B1 - 시냅토피신에 대한 특이적 결합 멤버 - Google Patents

시냅토피신에 대한 특이적 결합 멤버 Download PDF

Info

Publication number
KR101205655B1
KR101205655B1 KR1020067022596A KR20067022596A KR101205655B1 KR 101205655 B1 KR101205655 B1 KR 101205655B1 KR 1020067022596 A KR1020067022596 A KR 1020067022596A KR 20067022596 A KR20067022596 A KR 20067022596A KR 101205655 B1 KR101205655 B1 KR 101205655B1
Authority
KR
South Korea
Prior art keywords
domain
seq
specific binding
amino acid
binding member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020067022596A
Other languages
English (en)
Korean (ko)
Other versions
KR20060135046A (ko
Inventor
매튜 라이트
앤디 포터
Original Assignee
더 유니버시티 코트 오브 더 유니버시티 오브 애버딘
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0407059A external-priority patent/GB0407059D0/en
Priority claimed from GB0416402A external-priority patent/GB0416402D0/en
Application filed by 더 유니버시티 코트 오브 더 유니버시티 오브 애버딘 filed Critical 더 유니버시티 코트 오브 더 유니버시티 오브 애버딘
Publication of KR20060135046A publication Critical patent/KR20060135046A/ko
Application granted granted Critical
Publication of KR101205655B1 publication Critical patent/KR101205655B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis
    • G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020067022596A 2004-03-29 2006-10-27 시냅토피신에 대한 특이적 결합 멤버 Expired - Fee Related KR101205655B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0407059.5 2004-03-29
GB0407059A GB0407059D0 (en) 2004-03-29 2004-03-29 Specific binding members against synaptophysin
GB0416402.6 2004-07-22
GB0416402A GB0416402D0 (en) 2004-07-22 2004-07-22 Specific binding members against synaptophysin
PCT/GB2005/001190 WO2005095453A2 (en) 2004-03-29 2005-03-29 Specific binding members against synaptophysin

Publications (2)

Publication Number Publication Date
KR20060135046A KR20060135046A (ko) 2006-12-28
KR101205655B1 true KR101205655B1 (ko) 2012-12-13

Family

ID=35064446

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067022596A Expired - Fee Related KR101205655B1 (ko) 2004-03-29 2006-10-27 시냅토피신에 대한 특이적 결합 멤버

Country Status (8)

Country Link
US (2) US7871782B2 (https=)
EP (1) EP1735347B1 (https=)
JP (2) JP5020808B2 (https=)
KR (1) KR101205655B1 (https=)
CN (1) CN103130895A (https=)
CA (1) CA2584608C (https=)
PL (1) PL1735347T3 (https=)
WO (1) WO2005095453A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1735347T3 (pl) * 2004-03-29 2013-04-30 The Univ Court Of The Univ Of Aberdeen Specyficznie wiążące cząsteczki przeciwko synaptofizynie
CN105968209B (zh) 2011-04-19 2021-08-03 美国政府(由卫生和人类服务部的部长所代表) 对磷脂酰肌醇蛋白聚糖3特异的人单克隆抗体及其用途
KR102006997B1 (ko) * 2012-07-03 2019-08-02 한국생명공학연구원 ＩｇＧ Ｆｃ 위치선택적 결합 펩티드 및 이를 포함하는 하이브리드 분자
RU2689674C2 (ru) * 2012-10-15 2019-05-28 Медиммьюн Лимитед Антитела к бета-амилоиду
EP4516316A4 (en) * 2022-04-25 2026-04-22 Jiksak Bioengineering Inc TARGETING AGENT
WO2024055010A1 (en) * 2022-09-08 2024-03-14 Board Of Regents, The University Of Texas System Compositions for treating cancer and methods of using the same
WO2025089349A1 (ja) * 2023-10-25 2025-05-01 株式会社Jiksak Bioengineering 抗シナプトフィジン抗体
WO2025089347A1 (ja) * 2023-10-25 2025-05-01 株式会社Jiksak Bioengineering 抗シナプトフィジン抗体
WO2025089348A1 (ja) * 2023-10-25 2025-05-01 株式会社Jiksak Bioengineering 抗シナプトフィジン抗体
WO2025089343A1 (ja) * 2023-10-25 2025-05-01 株式会社Jiksak Bioengineering 抗シナプス小胞糖タンパク質２ｃ抗体
WO2025089346A1 (ja) * 2023-10-25 2025-05-01 株式会社Jiksak Bioengineering 抗シナプトフィジン抗体

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999020749A1 (en) 1997-10-20 1999-04-29 Medical Research Council Method to screen phage display libraries with different ligands

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3940209A1 (de) * 1989-12-05 1991-06-06 Boehringer Mannheim Gmbh Verfahren zum nachweis eines kleinzelligen bronchial-karzinoms
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
DE69222909T2 (de) * 1991-08-16 1998-03-12 Toshiba Kawasaki Kk Monoklonaler Antikörper gegen ein Synaptophysin
AU6424300A (en) 1999-05-27 2000-12-18 Max-Delbruck-Centrum Fur Molekulare Medizin Vaccines against conformation-dependent antigens and against antigens that are not or are not only proteins or peptides
JP2006510586A (ja) * 2002-08-29 2006-03-30 ユニバーシティー オブ サザンプトン 肝疾患治療のための薬剤の調製におけるアポトーシス誘導物質の使用方法
PL1735347T3 (pl) * 2004-03-29 2013-04-30 The Univ Court Of The Univ Of Aberdeen Specyficznie wiążące cząsteczki przeciwko synaptofizynie

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999020749A1 (en) 1997-10-20 1999-04-29 Medical Research Council Method to screen phage display libraries with different ligands

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of Hepatology, Vol.36, pp.200-209 (2002.02.)

Also Published As

Publication number Publication date
KR20060135046A (ko) 2006-12-28
EP1735347B1 (en) 2012-11-07
JP2008506358A (ja) 2008-03-06
JP5020808B2 (ja) 2012-09-05
WO2005095453A2 (en) 2005-10-13
EP1735347A2 (en) 2006-12-27
US20110165078A1 (en) 2011-07-07
US20080274123A1 (en) 2008-11-06
CA2584608C (en) 2015-03-17
WO2005095453A3 (en) 2006-04-06
WO2005095453B1 (en) 2006-12-21
US7871782B2 (en) 2011-01-18
JP2012162551A (ja) 2012-08-30
CN103130895A (zh) 2013-06-05
PL1735347T3 (pl) 2013-04-30
CA2584608A1 (en) 2005-10-13

Similar Documents

Publication Publication Date Title
US20110165078A1 (en) Specific binding members against synaptophysin
JP4869074B2 (ja) 抗体
KR101515243B1 (ko) 종양 전이암의 신생혈관과 관련된 피브리노겐의 ｅｄ―ａ 항원
DE60317677T2 (de) Ox40 (=cd134) rezeptor agonisten und therapeutische verwendung
KR101608544B1 (ko) 류마티스 관절염과 연관된 항원
JP6448554B2 (ja) 多発性硬化症を予防及び治療するための方法
WO2005044858A1 (en) Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor
US20190315846A1 (en) Antibodies to Human Alpha-Synuclein
US7612179B2 (en) antibodies binding to a C-terminal fragment of apoliopoprotein E
WO2001027279A1 (en) Human anti-adipocyte monoclonal antibodies and their use
SG188136A1 (en) HUMANIZED ANTIBODIES AGAINST THE ß-AMYLOYD PEPTIDE
US20230391852A1 (en) Single domain antibodies targeting sars coronavirus spike protein and uses thereof
WO2007099346A1 (en) Binding members for ghrelin
CN1980958A (zh) 抗突触泡蛋白的特异结合成员
GB2408332A (en) Phage display assay
HK40024078A (en) Human-derived anti-transthyretin antibody, polynucleotide, vector and use thereof
HK1159657A (en) Antibodies binding to a c-terminal fragment of apolipoprotein e
MXPA06005906A (en) Antibodies

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R17-X000 Change to representative recorded

St.27 status event code: A-5-5-R10-R17-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

FPAY Annual fee payment

Payment date: 20151123

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20161122

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20161122