KR101123510B1 - 신규한 아데노바이러스, 이를 암호화하는 핵산 및 이들의 조성물 - Google Patents

신규한 아데노바이러스, 이를 암호화하는 핵산 및 이들의 조성물 Download PDF

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KR101123510B1
KR101123510B1 KR1020057006313A KR20057006313A KR101123510B1 KR 101123510 B1 KR101123510 B1 KR 101123510B1 KR 1020057006313 A KR1020057006313 A KR 1020057006313A KR 20057006313 A KR20057006313 A KR 20057006313A KR 101123510 B1 KR101123510 B1 KR 101123510B1
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Prior art keywords
adenovirus
protein
promoter
nucleic acid
cells
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KR1020057006313A
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Korean (ko)
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KR20050061530A (ko
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페르 손네 홀름
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페르 손네 홀름
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Priority claimed from PCT/EP2003/005583 external-priority patent/WO2003099859A2/de
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Priority claimed from PCT/EP2003/011427 external-priority patent/WO2004035616A2/de
Publication of KR20050061530A publication Critical patent/KR20050061530A/ko
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/861Adenoviral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020057006313A 2002-10-15 2003-10-15 신규한 아데노바이러스, 이를 암호화하는 핵산 및 이들의 조성물 Expired - Fee Related KR101123510B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
DE10248039 2002-10-15
DE10248039.7 2002-10-15
DE10322530 2003-05-19
DE10322530.7 2003-05-19
PCT/EP2003/005583 WO2003099859A2 (de) 2002-05-27 2003-05-27 Neue verwendung von adenoviren und dafür codierenden nukleinsäuren
DE10324085.3 2003-05-27
DE10324085 2003-05-27
EPPCT/EP03/05583 2003-05-27
PCT/EP2003/011427 WO2004035616A2 (de) 2002-10-15 2003-10-15 Adenovirus mit umgekehrter reihenfolge der expression von genen und verwendung davon

Publications (2)

Publication Number Publication Date
KR20050061530A KR20050061530A (ko) 2005-06-22
KR101123510B1 true KR101123510B1 (ko) 2012-04-12

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KR1020057006313A Expired - Fee Related KR101123510B1 (ko) 2002-10-15 2003-10-15 신규한 아데노바이러스, 이를 암호화하는 핵산 및 이들의 조성물

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Country Link
JP (1) JP4988199B2 (https=)
KR (1) KR101123510B1 (https=)
AU (1) AU2003271730A1 (https=)
CA (1) CA2515650C (https=)
RU (1) RU2393221C2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2487811A1 (en) 2002-05-27 2003-12-04 Per Sonne Holm Use of adenoviruses replicating in a yb-1 dependent manner for the treatment of tumors
EP1689445B1 (de) 2003-11-14 2015-02-25 Per Sonne Holm Neue verwendung von adenoviren und dafür codierende nukleinsäuren
EP1689446B1 (de) * 2003-11-14 2015-01-07 Per Sonne Holm Neue adenoviren, dafür codierende nukleinsäuren und deren verwendung
EP1830864A2 (de) * 2004-12-31 2007-09-12 Per Sonne Holm E1 -minus adenoviren und deren verwendung
JP5584393B2 (ja) 2004-12-31 2014-09-03 ホルム,ペル・ゾンネ 動物細胞における多剤耐性を逆転させる方法
RU2561050C2 (ru) * 2013-08-28 2015-08-20 Федеральное государственное бюджетное учреждение науки Институт биофизики клетки Российской академии наук (ИБК РАН) Применение белка yb-1 и его фрагментов для изготовления лекарственных средств при лечении болезни альцгеймера
CA2925487C (en) * 2013-09-24 2023-11-07 University Of Washington Through Its Center For Commercialization Desmoglein 2 (dsg2) binding proteins and uses therefore in treating disorders associated with epithelial tissues
CA3092907A1 (en) * 2018-03-05 2019-09-12 Klinikum Rechts Der Isar Der Technischen Universitat Munchen Treatment of tumors by a combination of an oncolytic adenovirus and a cdk4/6 inhibitor
EP3822355A4 (en) * 2018-07-10 2022-05-18 Genemedicine Co., Ltd. ANTITUMOR COMPOSITION

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08507076A (ja) * 1993-02-16 1996-07-30 オニックス ファーマシューティカルズ,インコーポレイテイド 新形成の治療及び予防のための細胞障害ウイルス

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6254862B1 (en) * 1997-03-03 2001-07-03 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US6100086A (en) * 1997-04-14 2000-08-08 Genzyme Corporation Transgene expression systems
DE10015413A1 (de) * 2000-03-23 2001-09-27 Max Delbrueck Centrum Mittel zur Diagnose und Therapie viraler Erkrankungen
ES2287181T3 (es) * 2000-12-28 2007-12-16 Per Sonne Holm Sistemas adenovirales y sus aplicaciones.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08507076A (ja) * 1993-02-16 1996-07-30 オニックス ファーマシューティカルズ,インコーポレイテイド 新形成の治療及び予防のための細胞障害ウイルス

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Publication number Publication date
JP2006518589A (ja) 2006-08-17
AU2003271730A2 (en) 2004-05-04
JP4988199B2 (ja) 2012-08-01
CA2515650C (en) 2019-10-01
RU2393221C2 (ru) 2010-06-27
CA2515650A1 (en) 2004-04-29
KR20050061530A (ko) 2005-06-22
RU2005114516A (ru) 2006-01-20
AU2003271730A1 (en) 2004-05-04

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