KR101067159B1 - 개선된 생물학적 내약성을 갖는 조영제 제제 - Google Patents

개선된 생물학적 내약성을 갖는 조영제 제제 Download PDF

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Publication number
KR101067159B1
KR101067159B1 KR1020057010571A KR20057010571A KR101067159B1 KR 101067159 B1 KR101067159 B1 KR 101067159B1 KR 1020057010571 A KR1020057010571 A KR 1020057010571A KR 20057010571 A KR20057010571 A KR 20057010571A KR 101067159 B1 KR101067159 B1 KR 101067159B1
Authority
KR
South Korea
Prior art keywords
formulation
tris
carboxylic acid
organic amine
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020057010571A
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English (en)
Korean (ko)
Other versions
KR20050088312A (ko
Inventor
밀로스 소백
앨런 엘. 셀리그손
로널드 씨. 테리
Original Assignee
바이오피지카, 인크.
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Application filed by 바이오피지카, 인크. filed Critical 바이오피지카, 인크.
Publication of KR20050088312A publication Critical patent/KR20050088312A/ko
Application granted granted Critical
Publication of KR101067159B1 publication Critical patent/KR101067159B1/ko
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Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020057010571A 2002-12-12 2003-11-07 개선된 생물학적 내약성을 갖는 조영제 제제 Expired - Fee Related KR101067159B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US43287902P 2002-12-12 2002-12-12
US60/432,879 2002-12-12
US10/701,586 US7250153B2 (en) 2002-12-12 2003-11-05 Contrast media formulations having improved biological tolerance
US10/701,586 2003-11-05

Publications (2)

Publication Number Publication Date
KR20050088312A KR20050088312A (ko) 2005-09-05
KR101067159B1 true KR101067159B1 (ko) 2011-09-22

Family

ID=34107426

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057010571A Expired - Fee Related KR101067159B1 (ko) 2002-12-12 2003-11-07 개선된 생물학적 내약성을 갖는 조영제 제제

Country Status (18)

Country Link
US (1) US7250153B2 (enExample)
EP (1) EP1575621B1 (enExample)
JP (1) JP2006509841A (enExample)
KR (1) KR101067159B1 (enExample)
CN (1) CN1738651A (enExample)
AT (1) ATE447416T1 (enExample)
AU (1) AU2003295442B2 (enExample)
CA (1) CA2509035C (enExample)
CY (1) CY1110105T1 (enExample)
DE (1) DE60329939D1 (enExample)
DK (1) DK1575621T3 (enExample)
ES (1) ES2333863T3 (enExample)
IL (1) IL169119A (enExample)
NO (1) NO332350B1 (enExample)
NZ (1) NZ541139A (enExample)
PT (1) PT1575621E (enExample)
SI (1) SI1575621T1 (enExample)
WO (1) WO2004054637A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070015517A (ko) * 2004-03-11 2007-02-05 말린크로트, 인코포레이티드 요오드화된 단량체 및 이량체의 혼합물을 포함하는 ｘ-선조영제 제형
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
WO2009091758A1 (en) 2008-01-14 2009-07-23 Mallinckrodt Inc. Process for the preparation of iosimenol
RU2012138280A (ru) * 2010-03-23 2014-04-27 ДжиИ Хелткер АС Получение стабилизированной диагностической композиции для рентгеновского исследования

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19648650A1 (de) * 1996-01-29 1997-08-07 Schering Ag Puffersysteme zur Stabilisierung pharmazeutischer Zubereitungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR222337A1 (es) * 1978-07-04 1981-05-15 Nyegaard & Co As Procedimiento para preparar una solucion esteril inyectable fisiologicamente aceptable de un agente de contraste de rayos x
US5698739A (en) * 1989-07-05 1997-12-16 Schering Aktiengesellschaft Carboxamide non-ionic contrast media
KR19990022943A (ko) * 1995-06-16 1999-03-25 밀로스 소박 비이온성 조영제로서의 포르밀 유도체

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19648650A1 (de) * 1996-01-29 1997-08-07 Schering Ag Puffersysteme zur Stabilisierung pharmazeutischer Zubereitungen

Also Published As

Publication number Publication date
SI1575621T1 (sl) 2010-01-29
CY1110105T1 (el) 2015-01-14
US20050025711A1 (en) 2005-02-03
NO20053343D0 (no) 2005-07-08
AU2003295442A1 (en) 2004-07-09
NO20053343L (no) 2005-09-08
WO2004054637A3 (en) 2004-09-16
CA2509035C (en) 2011-07-19
WO2004054637A2 (en) 2004-07-01
US7250153B2 (en) 2007-07-31
IL169119A0 (en) 2007-07-04
PT1575621E (pt) 2009-11-13
CN1738651A (zh) 2006-02-22
CA2509035A1 (en) 2004-07-01
EP1575621B1 (en) 2009-11-04
EP1575621A4 (en) 2008-11-26
KR20050088312A (ko) 2005-09-05
ATE447416T1 (de) 2009-11-15
DE60329939D1 (de) 2009-12-17
ES2333863T3 (es) 2010-03-02
NO332350B1 (no) 2012-09-03
EP1575621A2 (en) 2005-09-21
JP2006509841A (ja) 2006-03-23
DK1575621T3 (da) 2009-12-14
AU2003295442B2 (en) 2008-11-06
IL169119A (en) 2010-06-16
NZ541139A (en) 2008-07-31

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