KR101008314B1 - Cd9이 과발현된 고형암의 항암제 개발을 위한표적단백질로서의 cd9의 용도 - Google Patents

Cd9이 과발현된 고형암의 항암제 개발을 위한표적단백질로서의 cd9의 용도 Download PDF

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KR101008314B1
KR101008314B1 KR1020080028576A KR20080028576A KR101008314B1 KR 101008314 B1 KR101008314 B1 KR 101008314B1 KR 1020080028576 A KR1020080028576 A KR 1020080028576A KR 20080028576 A KR20080028576 A KR 20080028576A KR 101008314 B1 KR101008314 B1 KR 101008314B1
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South Korea
Prior art keywords
cancer
ovarian cancer
expression
antibody
cells
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KR1020080028576A
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English (en)
Korean (ko)
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KR20090103163A (ko
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이제호
황재령
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성균관대학교산학협력단
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Priority to KR1020080028576A priority Critical patent/KR101008314B1/ko
Priority to PCT/KR2009/001576 priority patent/WO2009120039A2/fr
Publication of KR20090103163A publication Critical patent/KR20090103163A/ko
Application granted granted Critical
Publication of KR101008314B1 publication Critical patent/KR101008314B1/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020080028576A 2008-03-27 2008-03-27 Cd9이 과발현된 고형암의 항암제 개발을 위한표적단백질로서의 cd9의 용도 KR101008314B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020080028576A KR101008314B1 (ko) 2008-03-27 2008-03-27 Cd9이 과발현된 고형암의 항암제 개발을 위한표적단백질로서의 cd9의 용도
PCT/KR2009/001576 WO2009120039A2 (fr) 2008-03-27 2009-03-27 Utilisation de cd9 en tant que protéine cible afin de développer un médicament anticancéreux pour les tumeurs solides surexprimant cd9

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020080028576A KR101008314B1 (ko) 2008-03-27 2008-03-27 Cd9이 과발현된 고형암의 항암제 개발을 위한표적단백질로서의 cd9의 용도

Publications (2)

Publication Number Publication Date
KR20090103163A KR20090103163A (ko) 2009-10-01
KR101008314B1 true KR101008314B1 (ko) 2011-01-14

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Application Number Title Priority Date Filing Date
KR1020080028576A KR101008314B1 (ko) 2008-03-27 2008-03-27 Cd9이 과발현된 고형암의 항암제 개발을 위한표적단백질로서의 cd9의 용도

Country Status (2)

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KR (1) KR101008314B1 (fr)
WO (1) WO2009120039A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009157623A1 (fr) * 2008-06-25 2009-12-30 Korea Research Institute Of Bioscience And Biotechnology Anticorps humains spécifiques de cd9
WO2017026694A1 (fr) * 2015-08-11 2017-02-16 영남대학교 산학협력단 Composition pharmaceutique pour prévenir ou traiter des maladies oculaires, contenant en tant que principe actif un anticorps contre le cd9
EP3400245A1 (fr) 2016-01-08 2018-11-14 Aimm Therapeutics B.V. Anticorps anti-cd9 thérapeutique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004007685A2 (fr) * 2002-07-12 2004-01-22 The University Of Tennessee Research Foundation Procedes pour modifier le comportement des cellules exprimant cd9

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Actas Dermosifiliogr.(제96권, 제1호, 제30-36면, 2005년)*
Human pathology(제35권, 제8호, 제1014-1021면, 2005년)*

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Publication number Publication date
KR20090103163A (ko) 2009-10-01
WO2009120039A2 (fr) 2009-10-01
WO2009120039A3 (fr) 2009-11-26

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