KR100877091B1 - Pesticidal methods and uses - Google Patents

Abstract

The present invention provides pest control methods and uses. The method comprises applying 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate to the surface of a structure or household article. It includes.

Description

Pest Control Methods and Uses {PESTICIDAL METHODS AND USES}

The present invention relates to pest control methods and uses.

USP 4,889,872 discloses 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate as a pesticidal compound.

It is well known that sustained pesticidal control against non-invasive pests in an indoor environment can be done by applying the pesticidal active compounds directly to the non-invasive pests or by dispersing the pesticidal active compounds in an indoor environment with an electrical device. Direct application of pesticidal active compounds to non-communicating pests necessitates the use of a pesticidal active compound on a case-by-case basis in which the pesticidal active compound is repeatedly sprayed on the non-communicating pests whenever the non-communicating pest enters the indoor environment. Dispersing pesticidal active ingredients generally requires the continuous operation of the electrical device. So far such pesticidal techniques generally require active and boring performance of the technique while the homeowner is in an indoor environment.

Summary of the Invention

The present invention provides a 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxyl for controlling non-commercial pests in indoor environments. The use of the rate and the method of pest control in indoor environment is provided. The method applies 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate to the surface of a structure or household article. It includes.

In the process of the invention, the insecticidal compound of 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate is constructed Or on the surface of household articles. The application is usually to impregnate the surface of the structure or household article with a pesticidal compound. After impregnation, the applied pesticidal compound is automatically vaporized at room temperature so that the vaporized pesticidal compound can control the non-invasive pest.

The structure may generally be a fixture of a building that constitutes an interior compartment of the building. Examples of structures include ceilings, interior walls, columns, handrails (working dividers on sliding dividers between two rooms), windows, awnings, floors, doors, and the like. Examples of buildings include houses, offices and apartments. In the application of insecticidal compounds to the surface of the structure, the insecticidal compounds may be applied to the paints present in the structure, the wallpaper present on the interior walls, the plaster present on the ceiling, the carpets laid on the floor, the floor tiles.

The household article may be a mobile household product which is generally located in the building room for a prolonged period of time, such as for more than one month. Such household items can generally be moved outside the building room. Household articles can be made of cloth, wood, plastic, metal, and the like. Examples of household items include curtains, furniture (drawers, storage shelves, fluorescent lamps, desks, chairs), scrolls (hanging scrolls or hanging pictures), fossils (cloths in a roof), blinds, piano, vases, Carpets and the like. When applied to the surface of household articles, the insecticidal compounds may be applied in the paints present in household articles, finishing agents on wooden furniture and the like.

When applying pesticidal compounds to the surface of the structure or the surface of household articles, the pesticidal compounds may be used in various forms, such as aerosol formulations, oily formulations, aqueous liquid formulations, mist formulations, heater formulations, blower formulations, and the like. Formulation forms may be used. When using an aerosol formulation, the aerosol formulation can be sprayed directly or indirectly onto the surface of the structure or household article. When using oily formulations or aqueous liquid formulations, the oily formulations or aqueous liquid formulations can be spread directly on the surface of the structure or household article, for example by brushing or combing. When using mist formulations or wholly sprayed aerosol formulations, the mist formulations or wholly sprayed aerosol formulations may be indirectly applied to the surface of the structure or household article. In such cases, the mist formulations or full spray aerosols are activated in a closed room such that the pesticidal compounds disperse into the indoor air space and the pesticidal compounds settle on the surface of the structure or household article. Typically, after activation of the mist formulation or full spray aerosol formulation, the time sufficient for the pesticidal compound to settle on the surface of the structure or household article is 2-3 hours. Typically, aerosol formulations and full spray aerosol formulations are used when the homeowner is not indoors.

In the application of pesticidal compounds, the pesticidal compounds are generally applied such that an insecticidal effective amount of the pesticidal compound is applied to the surface of the household article or structure. The application of such a pesticidal compound may apply 0.1 to 1000 mg or 1 to 500 mg of the pesticidal compound to the surface of the structure or household article every 1 m 3 of the application space. This amount is usually sufficient for an effective amount of pesticidal compound for non-commercial pest control to vaporize at room temperature.

Formulations of pesticidal compounds typically have an amount of from 0.001 to 30% by weight of the pesticidal compound present therein, wherein the weight percentage is based on the total weight of the formulation provided.

Aerosol formulations typically have pesticidal compounds and propellants therein. In such aerosol formulations, the aerosol formulations typically have an insecticidal compound present in the amount of from 0.001 to 20% by weight, wherein the weight percent is based on the total weight of the formulation provided.

As propellants in the aerosol composition, mention may be made of compounds having a boiling point of 25 ° C. or lower, which can provide an aerosol formulation in a homogeneous mixture. Examples of such propellants include dimethyl ether (boiling point −24.8 ° C.), propane (boiling point −42.1 ° C.), n-butane (boiling point −0.5 ° C.), isobutane (boiling point −12 ° C.), and mixtures thereof.

Propellants are generally present in the aerosol formulation in an amount such that the pesticidal compound is sprayed at least efficiently on the surface of the structure or household article. The amount of such propellant present in the aerosol formulation may be at least 20% by weight, or from 20 to 99.999% by weight (wherein the weight percentage is based on the total amount of aerosol formulation provided).

If desired, a solvent may be added thereto, wherein the solvent has a boiling point of 30 to 210 ° C. at 1 atmosphere. It is preferable that a solvent has a boiling point of 30-120 degreeC, and it is more preferable that a boiling point is 30-100 degreeC (wherein the said boiling point is measured at 1 atmospheric pressure). The solvent whose boiling point is 30-210 degreeC means that the boiling point of all the components which provide a solvent is in the range of 30-210 degreeC substantially. When using a mixture of solvents in an aerosol formulation, the aerosol formulations typically fall within the boiling ranges described above for each solvent.

In addition, the aerosol formulations preferably utilize a solvent therein which can provide the aerosol formulation in a uniform mixture. When the aerosol formulations are in a homogeneous mixture, the aerosol formulations may be in solution as opposed to the presence of separated water and oil layers, emulsion and suspension. However, the aerosol formulation may also be in such a separated aqueous and oily phase, in an emulsion state or in a suspended state.

Examples of such solvents include water (boiling point 100 ° C.), n-butyl alcohol (boiling point 117.9 ° C.), sec-butyl alcohol (boiling point 99.5 ° C.), tert-butyl alcohol (boiling point 82.3 ° C.), n-propyl alcohol ( Boiling point 97.2 ° C), isopropyl alcohol (boiling point 82.4 ° C), ethyl alcohol (boiling point 78.3 ° C), hexane (boiling point 69 ° C), heptane (boiling point 98.4 ° C), 2-methylpentane (boiling point 60 ° C), 2,2- Dimethylbutane (boiling point 50 ℃), octane (boiling point 125 ℃), nonane (boiling point 149.5 ℃), decane (boiling point 174 ℃), undecane (boiling point 195.9 ℃), IP 1620 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 166 -202 ° C), IP 1016 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 73-140 ° C) and the like can be mentioned. In providing the aqueous aerosol formulation in a homogeneous mixture, alcohols such as isopropanol may also be added as solvent.

If used, the solvent is present in the aerosol formulation in an amount of up to 79.9999 weight percent, preferably 5 to 60 weight percent (the weight percent being based on the total weight of the provided aerosol formulation).

Formulations can be prepared by conventional techniques. For example, an aerosol formulation can be prepared as follows: Insecticidal compounds are added to an aerosol container. If necessary, a solvent, another pesticidal active compound, a repellent, a synergist and / or a stabilizer are also added to the aerosol container. After attaching the aerosol valve to the aerosol container, the propellant is filled into the aerosol container through the valve. Shake the aerosol container to mix the contents in the aerosol container and mount the actuator to the aerosol container.

Oily formulations can be prepared according to the method described in Japanese Patent Laid-Open No. 6-316503.

Aqueous liquid formulations can be prepared according to the method described in Japanese Patent Laid-Open No. 6-9305.                     

The mist formulation can be prepared according to the method described in Japanese Patent Laid-Open No. 5-294803.

Heater formulations may be prepared according to the method described in Japanese Patent Publication No. Hei 2-533332 or Japanese Patent Laid-Open No. Hei 6-9305.

The blower formulation can be prepared according to the method described in Japanese Patent Laid-Open No. 11-92303.

Examples of emergency pests include unsanitary emergency pests and unpleasant emergency pests. More specific examples of unhygienic pests include flies, such as Musca domestica and Muscina stabulans, red colonies (Culex pipiens pallens), Cules tritaeniorhynchus, and Culex Quinquepasciatus ( Mosquitoes such as Culex quinquefasciatus and Aedes albopictus are mentioned. More specific examples of unpleasant pests include midget (Chironmidae), moth flies (Psychodidae), ants (Formicidae), wasps (Vespidae), bees and the like.

Example

Formulation Examples 1-7

A pesticidal compound, 1R-trans-2,3,5,6-tetrafluorobenzyl-3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate, is prepared as described in Table 1 Amount is added to the aerosol container. When used, IP 1620 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 166-202 ° C.) is also added to the aerosol container in the amounts shown in Table 1. After attaching an aerosol valve to the aerosol container, propellant dimethyl ether is charged to the aerosol container in the amount shown in Table 1. Shake the contents of the aerosol container well. The actuator is then attached to the aerosol container to prepare aerosol formulations 1-7.

Aerosol Formulation Number Amount of pesticidal compound (g) menstruum Volume of propellant (g) type Volume (g) One One IP 1620 69 30 2 0.025 none 0 99.975 3 0.05 none 0 99.95 4 0.1 none 0 99.9 5 0.2 none 0 99.8 6 0.5 none 0 99.5 7 One none 0 98

Formulation Examples 8-37

In an aerosol container, a specific solvent as described in Table 2 below was added to the pesticidal compound 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethyl It is mixed with cyclopropanecarboxylate in the amount shown in Table 2. As shown in Table 2, the solvents used were IP 1620 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 166-202 ° C), IP 1016 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 73-140 ° C), isopropyl Selected from alcohol and hexane. After attaching an aerosol valve to the aerosol container, dimethyl ether as a propellant is filled into the aerosol container in the amounts shown in Table 2. Shake the contents of the aerosol container well. The actuator is then attached to the aerosol container to produce aerosol formulations 8-37.                     

Formulation Examples 38-74

Using LPG instead of dimethyl ether, aerosol formulations 38-74 are prepared analogously to Formulation Examples 8-37.

Formulation Example 75

1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) as an insecticidal compound in 97.33 g of IP 1620 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 166-202 ° C) An oily formulation is prepared by dissolving 2.67 g of -2,2-dimethylcyclopropanecarboxylate. The oily formulation is poured into an aerosol container. After attaching the aerosol valve to the aerosol container, 8.4 g of a liquefied injection gas mixture of dimethyl ether and LPG are charged into the aerosol container. Shake the contents of the aerosol container well. An aerosol formulation 75 is then prepared by attaching the full jet aerosol actuator to the aerosol container.

Formulation Example 76

In an aerosol container, a 1: 1 solvent mixture (by weight) of water and isopropanol was added to the pesticidal compound 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl)- Add with 2,2-dimethylcyclopropanecarboxylate. After attaching an aerosol valve to the aerosol container, 50 g of dimethyl ether is charged to the aerosol container. Shake the contents of the aerosol container well. The actuator is then mounted in an aerosol container to produce aerosol formulation 76.

Comparative Formulation Example 1

In an aerosol container, 69 g of IP 1620 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 166 to 202 ° C.) is added together with 1 g of empentrin. After attaching an aerosol valve to the aerosol container, 30 g of propellant dimethyl ether are charged into the aerosol container. Shake the contents of the aerosol container well. The actuator is then attached to the aerosol container to prepare Comparative Aerosol Formulation 1.

Comparative Formulation Example 2

In an aerosol container, 69 g of IP 1620 (Idemitsu Petrochemical Company, isoparaffin solvent, boiling point 166-202 ° C.) is added together with 1 g of permethrin. After attaching an aerosol valve to the aerosol container, 30 g of propellant dimethyl ether are charged into the aerosol container. Shake the contents of the aerosol container well. The actuator is then attached to the aerosol container to prepare Comparative Aerosol Formulation 2.

Test Example 1

In a 5.8 m3 laboratory (inside area: 1.8 m wide, 1.8 m deep, 1.8 m high, where one of the four walls is glass), a 1 m² nylon curtain was opened on a glass window 140 cm from the floor. . At a point 20 cm away from the curtain, Aerosol Formulation 1 was sprayed onto the nylon curtain uniformly and directly for 6 seconds. Aerosol Formulation 1 The amount of aerosol formulation 1 that has been sprayed was determined by measuring the reduced amount in the total weight of the aerosol composition 1 from before and after spraying. Subsequently, the laboratory was vented for 10 minutes with an exhaust fan. The entrance to the laboratory was then closed and sealed. The following day (after 1 day), the laboratory was ventilated for 10 minutes a second time, and then 20 adult male and female houseflies were released to the laboratory. The knock down number of the housefly was periodically observed for a predetermined time. In addition, after 2 days and 3 days of spraying of Aerosol Formulation 1, the laboratory was ventilated for the third and fourth times, respectively, leaving no home flies in the laboratory. After the fourth ventilation, 20 adult male and female houseflies were released for the second time in the laboratory. The knockdown number of the housefly was periodically observed for a predetermined time. Based on the knockdown number, the time taken for half of the housefly to knock down was determined after the first day and after the third day (KT ₅₀ ).

In addition, the test was repeated with Comparative Aerosol Formulation 1 and Comparative Aerosol Formulation 2, respectively.

The results are shown in Table 3 below.

Amount Sprayed (g) KT ₅₀ value (min) 1 day later 3 days later  Aerosol Formulations 1 Comparative Aerosol Formulations 1 Comparative Aerosol Formulations 2       3.4 3.3 3.1      4.2 6.4 18.4      6.8 greater than 60 34.3

Test Example 2

The test in Test Example 1 is repeated with the aerosol compositions 7, 8, 14, 15, 22, 23, 29, 30, 36 and 37. Excellent pesticidal effects are achieved with aerosol compositions 7, 8, 14, 15, 22, 23, 29, 30, 36 and 37.

Test Example 3

The aerosol composition 75 was placed in the center of the floor in a 5.8 m 3 laboratory (inner area: 1.8 m wide, 1.8 m deep, 1.8 m high), and all the contents of the aerosol composition 75 were indirectly sprayed upwards (about 17 seconds). Aerosol Formulation 75 The amount of aerosol formulation 75 sprayed was determined by measuring the reduced amount in the total weight of the aerosol composition 75 from before and after spraying. Subsequently, the laboratory was vented for 10 minutes with an exhaust fan. The entrance to the laboratory was then closed and sealed. The next day (after 1 day), the laboratory was vented a second time with an exhaust fan for 10 minutes. Fifty adult male and female houseflies were released into the laboratory while the laboratory was closed and sealed. The knockdown number of the housefly was periodically observed for a predetermined time. In addition, after 2 days and 3 days of spraying of the aerosol formulation 75, the laboratory was ventilated for the third and fourth times, respectively, leaving no home flies in the laboratory. After the fourth ventilation, 50 adult male and female houseflies were released for the second time in the laboratory. The knockdown number of the housefly was periodically observed for a predetermined time. Based on the knockdown number, the time taken for half of the housefly to knock down was determined after the first day and after the third day (KT ₅₀ ).

The results are shown in Table 4 below.

Application composition Aerosol Spray Volume (g) KT ₅₀ value (min) 1 day later 3 days later   Aerosol Compositions 75        12     Less than 2.0       2.3

The present invention provides a 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxyl for controlling non-commercial pests in indoor environments. The use of the rate and the method of pest control in indoor environment is provided. The method applies 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate to the surface of a structure or household article. It includes. The application is usually to impregnate the surface of the structure or household article with a pesticidal compound. After impregnation, the applied pesticidal compound is automatically vaporized at room temperature so that the vaporized pesticidal compound can control the non-invasive pest.

Claims (5)

As a method of controlling flies or mosquitoes in an indoor environment, 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate may be used to construct or A method comprising applying to the surface of a household article. The aerosol according to claim 1, which contains a propellant and 1R-trans-2,3,5,6-tetrafluorobenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate. Spraying the composition onto the surface of the structure or household article. The method according to claim 2, wherein the aerosol composition further contains a solvent having a boiling point of 30 ° C to 210 ° C. The method of claim 1, wherein the structure and household articles are selected from fixtures of the building, and mobile furniture products. delete