KR100773758B1 - Feed composition containing mineral coated with nano silver - Google Patents

Abstract

When the feed composition is used in poultry and livestock, the present invention minimizes the amount of antibiotics in the body and facilitates metabolism with the health function of silver nano inorganic salts, thereby reducing cholesterol and triglyceride content to provide meat with appropriate protein content. It provides a feed composition that can be. In addition, in the case of meat produced by ingesting the feed of the present invention, it is possible to provide meat intake to the health functionalities of the silver nano material contained in the meat.

Silver nano, inorganic salt, feed composition, poultry, livestock, antibiotic, meat quality

Description

Feed composition containing mineral coated with nano-silver

The present invention relates to a feed composition in which inorganic salts used in poultry and livestock feed are replaced with silver nano inorganic salts, and the amount of antibiotics is greatly reduced. More specifically, the present invention minimizes the amount of antibiotics in the body when ingested in poultry and livestock and facilitates metabolism with the health function of silver nano inorganic salts to reduce cholesterol and triglyceride content and to have proper protein and lipid content. The present invention relates to a feed composition capable of providing a health function of silver ions contained in meat.

Cholesterol is a kind of steroid compound widely found as a cellular component of higher animals. It is a component of all animal cells necessary for growth and maintenance, regulates the physical state of biological membranes, and is a precursor of steroid hormones, vitamin D and bile acids. But myelin and plasma lipoproteins of the brain are essential components of the human body as components.

Various studies are underway to reduce cholesterol content in order to prevent various types of adult diseases such as atherosclerosis, obesity, hypertension, angina pectoris, myocardial infarction, and stroke. And research on the production of meat products that lower triglyceride content and improve the quality of the protein and research on livestock feed that can provide such meat products are being actively made.

Republic of Korea Patent Application No. 2004-115675 'Feeding method for livestock feed using bio ceramic material and silver ion water' discloses a feed method for livestock feed using bioceramic material and silver ion water. However, the patent document discloses only a method of feeding livestock by feeding silver ionized water and a method of feeding inorganic salts of a bioceramic system in the feed composition, and do not disclose silver nano inorganic salts and antibiotic contents. Accordingly, there is no change in the antibiotic content used as feed additive.

In addition, Korean Patent Registration No. 451,545, "Method for preparing a mixed composition for adding piglets containing hydrochloric acid and silicate minerals, said mixed composition and feed" discloses a mixed composition for adding piglets prepared with an inorganic acid and a silicate salt mineral. , The feed composition is based on the acid (HCl) and Korea. However, the composition for feed addition disclosed in the patent is different from the silver nano-coated inorganic salts of the present invention, that is, in the case of the present invention by silver nano-coated inorganic salts such as sodium chloride, calcium chloride, potassium chloride, magnesium chloride, sodium sulfate On the contrary, the feed disclosed in the patent document contains silicate mineral as a main component.

Meanwhile, Korean Patent Application No. 2003-100043, 'Compound feed containing selenium as an active ingredient, and a method of manufacturing functional livestock and fruit vegetables using the same,' refers to the accumulation of these substances in livestock through the intake of selenium in livestock and A method for producing a functional fruit vegetable containing a large amount of a functional substance by fertilization of these feces is disclosed. In addition, it is disclosed that the feed of selenium is added and the fat is stable, so that the meat can be actively produced. However, the technique disclosed in this patent document is based on the mineral effect of selenium and is different in composition from the feed composition of the present invention containing inorganic salts coated with silver nanomaterial.

Therefore, the present invention minimizes the amount of antibiotics in the body when ingested in poultry and livestock and facilitates metabolism, thereby reducing cholesterol and triglyceride content to provide a poultry and livestock feed for providing a meat having an appropriate protein and lipid content. In order to develop more effective feed composition by changing the content and composition of inorganic salt additives and antibiotics in the feed composition, the present invention was developed by replacing inorganic salts with silver nano inorganic salts and greatly reducing the amount of antibiotics. The invention is completed.

The technical problem to be achieved in the present invention is to replace the inorganic salts used in feed for poultry and livestock with silver nano-coated inorganic salts and to develop a feed composition that significantly reduced the amount of antibiotics. That is, when the feed composition of the present invention is used and consumed in poultry and livestock, the amount of antibiotics in the body is minimized and the metabolism is smoothed by the health function of silver nano inorganic salts, thereby reducing the content of cholesterol and triglycerides to reduce meat content with an appropriate protein content. It has developed a feed composition that can provide. In addition, in the case of meat produced by ingesting the feed of the present invention, it is possible to provide a meat intake to the health functionalities of the silver nano material contained in the meat.

An object of the present invention is 0.01 to 3 parts by weight of silver nano-coated inorganic salts, antibiotics based on 100 parts by weight of feed grains containing at least one sugar, protein, lipid selected from corn, soybean, soybean meal, wheat, soybeans, barley, rice bran It is to provide a feed composition comprising 0.001 to 0.1 parts by weight.

In addition, the silver nano-coated inorganic salts are characterized by containing 0.01 to 0.5 parts by weight of the silver nano compound with respect to 1 part by weight of one or more inorganic salts selected from sodium chloride, calcium chloride, potassium chloride, magnesium chloride, sodium sulfate.

In this case, the silver nano-coated inorganic salts are prepared by vapor deposition of silver nano particles having a particle size of 1 to 50 nm on the inorganic salts.

Hereinafter, the present invention will be described in more detail.

The silver nano inorganic salts used in the present invention are silver nano inorganic particles using a method of manufacturing a nano-attached powder (NAP), which is a method of vapor-depositing 99.99% of silver particles of nano size in a vacuum using a physical vapor deposition method using inorganic salts as a core material. Salts were prepared.

The silver nano inorganic salts prepared by the NAP manufacturing method are capable of producing high purity (99.99%) silver nano particles and easily control the size of the nano particles, thereby depositing 1-50 nm silver nano particles on the refined inorganic salts to provide excellent stability of the nano particles. Is characteristic. In addition, silver nano particles deposited on inorganic salts have sterilization and deodorization functions.

When these silver nano inorganic salts are included as feed and ingested in poultry and livestock, they reduce metabolism of all harmful bacteria in the body and promote metabolism by selecting and disinfecting harmful bacteria in the intestine. In addition, silver has no side effects and is released into the body within 3 days after ingestion, and activates healthy cells of the living body, thereby increasing the immunity of poultry and livestock. Therefore, in the case of the present invention, by mixing silver nano inorganic salts into feed and feeding to poultry and livestock, not only does it increase the bactericidal power against intestinal harmful bacteria and increase immunity, but also smoothes metabolism and decreases the fat content, so that the appropriate protein and lipid content It provides a feed composition that can provide a meat quality with.

The content of the silver nano-coated inorganic salts in the feed composition to expect the above effects should contain at least 0.01 parts by weight or more, and up to 3 parts by weight of silver nano-coated inorganic salts may be added to the feed composition. If the content of the silver nano-coated inorganic salt is 0.01 parts by weight or less, the content of the silver nano-particles is too small to affect the metabolism of the poultry or livestock ingested it can not provide the desired meat quality in the present invention, silver nano-coated When the inorganic salt content exceeds 3 parts by weight, not only the cost of the feed composition increases but also a significant improvement in its effect cannot be expected.

On the other hand, in the case of antibiotics put into the feed is completely digested and discharged after 2 to 3 weeks, when the antibiotics are shipped before fully digested and discharged, there is a problem that causes the residual amount of antibiotics in the meat due to the remaining antibiotics present in the body. In addition, the increase in antibiotic-resistant bacteria in the body caused by antibiotic abuse may cause the genetic material containing resistance to be transferred to other bacteria by the transfer of plasmid conjugation, which increases the growth of antibiotic-resistant bacteria from meat products to the human body. There is a risk of metastasis. For these reasons, antibiotic restrictions in meat products have recently been severely limited.

Therefore, many feed compositions have been recently developed to minimize the amount of antibiotics. However, minimizing the content of antibiotics inhibits the growth of poultry and livestock, making it difficult to achieve poultry and livestock growth of desired weight. This can be

However, in the present invention, it is possible to minimize the content in the feed composition of the antibiotic due to the health function of the silver nano-coated inorganic salts, in particular antibacterial to the harmful bacteria in the intestine, and therefore the feed composition containing at least 0.001 parts by weight of antibiotics in the feed composition of the present invention In any case, the content of the antibiotic does not exceed 0.1 parts by weight. Given that the antibiotic content in the conventional feed is 0.1 to 0.8 parts by weight based on 100 parts by weight of feed grains, the antibiotic content of the feed composition of the present invention is significantly reduced.

The present invention will be described in more detail with reference to the following examples. However, these examples do not limit the scope of the present invention.

Preparation Example 1 Preparation of Silver Nano Inorganic Salt-Containing Feed Composition

To prepare a feed composition comprising 0.5 parts by weight of silver nano-coated inorganic salts, 0.01 parts by weight of antibiotics based on 100 parts by weight of feed grains containing one or more sugars, proteins, lipids selected from corn, soybean, wheat, soybeans, barley, rice bran do. In addition, the silver nano-coated inorganic salts contain 0.1 parts by weight of silver nano compounds based on 1 part by weight of one or more inorganic salts selected from sodium chloride, calcium chloride, potassium chloride, magnesium chloride, and sodium sulfate, wherein the silver nano-coated inorganic salts have a particle size of 5 It is produced by vapor-depositing silver nanoparticles of -30 nm in inorganic salts.

Preparation Example 2 Preparation of Silver Nano Inorganic Salt-Containing Feed Composition

To prepare a feed composition comprising 0.6 parts by weight of silver nano-coated inorganic salts, 0.015 parts by weight antibiotics based on 100 parts by weight of feed grains containing one or more sugars, proteins, lipids selected from corn, soybean, wheat, soybeans, barley, rice bran do. In addition, the silver nano-coated inorganic salts contain 0.15 parts by weight of silver nano compounds based on 1 part by weight of one or more inorganic salts selected from sodium chloride, calcium chloride, potassium chloride, magnesium chloride, and sodium sulfate, wherein the silver nano-coated inorganic salts have a particle size of 5 It is produced by vapor-depositing silver nanoparticles of -30 nm in inorganic salts.

Preparation Example 1 Preparation of Inorganic Salt-Containing Feed Composition

A feed composition comprising 0.5 parts by weight of inorganic salts and 0.01 parts by weight of antibiotics is prepared for 100 parts by weight of feed grains containing one or more sugars, proteins, lipids selected from corn, soybean, wheat, soybean, barley and rice bran. Inorganic salts are selected from sodium chloride, calcium chloride, potassium chloride, magnesium chloride, sodium sulfate.

Preparation Example 2 Preparation of Feed Composition with Increased Antibiotic Content

To prepare a poultry feed composition comprising 0.5 parts by weight of inorganic salts, 0.5 parts by weight of antibiotics based on 100 parts by weight of feed grains containing one or more sugars, proteins, lipids selected from corn, soybean, wheat, soybeans, barley, rice bran. . Inorganic salts are selected from sodium chloride, calcium chloride, potassium chloride, magnesium chloride, sodium sulfate.

Example 1 Growth according to Feed Intake of Broiler Chickens

As the experimental animals, 40 animals of 5 week old broiler chickens (ISA brown leghorn) were placed at random. Indoor temperature of the experimental animal breeding room was adjusted to 25 ℃, relative humidity 50%, contrast 16L: 8D conditions. Broiler chickens were fed for six weeks by free feeding of water and experimental diets prepared in Preparation Examples 1 and 2 and Comparative Examples 1 and 2. A test group ingesting the feed prepared in Preparation Example 1 is called a first group, and a test group ingesting the feed prepared in Preparation Example 2 is called a second group, and consumed the feed prepared in Preparation Example 1 This test group is called a third group, and the test group ingested the feed prepared in Preparation Example 2 is called a fourth group. Growth of broilers in each test group was measured after feeding for 6 weeks. Daily weight gain, daily feed intake and feed efficiency for each test group were measured and the results are shown in Table 1.

division First group 2nd group 3rd group 4th group Daily Feed Intake (g) 140 140 140 140 Weight gain per day (g) 28.50 29.30 23.70 24.30 Feed efficiency 0.20 0.20 0.17 0.17

The feed efficiency was 0.20 in the first and second groups fed the feed of the present invention, and the feed efficiency was 0.17 in the third and fourth groups fed the general feed. Therefore, it can be seen that the feed of the present invention is more effective for the growth of broilers.

Example 2 Growth according to Feed Intake of Pork

As experimental animals, 40 pigs of three-way hybrids (Duroc × Yorkshire × Landrace) were completely randomly placed in 10 rats. Indoor temperature of the experimental animal breeding room was adjusted to 25 ℃, relative humidity 50%, contrast 16L: 8D conditions. Swine pigs were fed for six weeks by free feeding of water and experimental diets prepared in Preparation Examples 1 and 2 and Comparative Examples 1 and 2. A test group ingesting the feed prepared in Preparation Example 1 is called a fifth group, a test group ingesting the feed prepared in Preparation Example 2 is called a sixth group, and the feed prepared in Preparation Comparative Example 1 is ingested. This test group is called a seventh group, and the test group ingested the feed prepared in Preparation Comparative Example 2 is called an eighth group. Growth of pigs in each test group was measured after feeding for 6 weeks. Daily weight gain, daily feed intake and feed efficiency for each test group were measured and the results are shown in Table 2.

division Fifth group 6th group 7th group 8th Army Daily Feed Intake (g) 1000 1000 1000 1000 Weight gain per day (g) 354 346 286 305 Feed efficiency 0.35 0.35 0.29 0.30

Feed efficiency was 0.35 in the fifth and sixth groups fed the feed of the present invention, and 0.29 and 0.30 in the seventh and eighth groups fed the general feed. Therefore, it can be seen that the feed of the present invention is more effective for growing pigs.

Example 3 Component Analysis of Chicken Meat

Moisture, crude protein, crude fat, crude ash and cholesterol content were measured to evaluate the meat quality obtained by slaughtering the grown broilers of each group of the first to fourth groups. Moisture was measured by drying method, crude protein by Kjeldahl method, crude fat by Soxhlet extraction method, and crude ash by 550 ℃ electric chemistry. The results are shown in Table 3.

division First group 2nd group 3rd group 4th group Cholesterol (mg / 100g) 93 91 105 104 moisture (%) 70.31 70.84 69.41 69.89 Crude fat (%) 5.18 5.09 6.24 6.26 Crude Protein (%) 20.41 21.30 18.11 18.84 View% (%) 1.14 1.18 1.17 1.16

Cholesterol content and crude fat content of the broilers of the test group 1 and 2 fed the feed of the present invention was reduced compared to the 3 and 4 groups fed the normal feed and the crude protein content of the general feed Increased compared to the ingested group. However, the contents of moisture and crude ash did not show a significant difference between the test groups.

Example 4 Component Analysis of Pork

Moisture, crude protein, crude fat, crude ash, and cholesterol content were measured to evaluate the meat quality obtained by slaughtering the grown pork from each group of the fifth to eighth groups. Moisture was measured by drying method, crude protein by Kjeldahl method, crude fat by Soxhlet extraction method, and crude ash by 550 ℃ electric chemistry. The results are shown in Table 3.

division Fifth group 6th group 7th group 8th Army Cholesterol (mg / 100g) 48.38 50.74 54.35 53.10 moisture (%) 69.14 69.48 70.41 70.86 Crude fat (%) 8.04 8.34 10.71 10.50 Crude Protein (%) 18.94 19.10 16.38 16.67 View% (%) 2.17 2.20 2.28 2.24

Cholesterol content and crude fat content of the pigs of the test group 5 and 6 fed the feed of the present invention was reduced compared to the 7 and 8 groups fed the normal feed and the crude protein content of the general feed Increased compared to the ingested group. However, the contents of moisture and crude ash did not show a significant difference between the test groups.

Example 5 Antibiotic Efficacy Test

To the test animals of the test group 1 to 4 group and the test group 5 to 8 group ingested in broiler feed the broilers prepared in Preparation Examples 1, 2 and Comparative Examples 1, 2 The feed was fed for 3 months and the test group animals were bred under the same conditions to investigate the number of affected and lethal individuals that occurred in the test group during the latter 2 months. The most common causes were diarrhea, infectious gastroenteritis, Ozeski's disease, genital respiratory syndrome, atrophic rhinitis, pneumonia, coliform bacterium, toxoplasma disease, exudative epidermatitis, and salmonella. The results are shown in Table 5.

division Onset population Lethal population First group 3 One 2nd group 2 0 3rd group 6 4 4th group 3 One Fifth group 3 0 6th group 2 0 7th group 7 4 8th Army 4 One

The killing population was less than 10% in the test group 1 and 2 of broilers fed the feed of the present invention. On the other hand, the test group 5 and 6 group of pigs fed the feed of the present invention also showed no lethal population. However, in the case of the test group 3 and 7 fed the feed prepared in Preparation Example 1 having a reduced antibiotic content and the ordinary inorganic salts containing no silver nano-containing inorganic salts of the present invention, the mortality rate was 40%. Reached. This indicates that silver nano-containing inorganic salts replace the function of antibiotics.

In addition, the killing rate was about 10% in the test group 4 and 8, which consumed the feed prepared in Preparation Example 2, which increased the content of antibiotics instead of silver nano inorganic salts. However, in the case of test group 4 and 8, cholesterol was lowered compared to test group 1, 2, 5 and 6, which were fed the feed of the present invention according to the meat quality analysis according to Examples 3 and 4. As a result, the fat content was increased and the protein content was decreased.

From the above examples, broilers or pigs of the first, second, fifth, and sixth groups fed the feed of the present invention had excellent growth, increased protein content, and decreased cholesterol and fat content. It can be appreciated that the disease prevalence and lethality are significantly reduced in broilers or pigs fed the feed of the present invention.

The effect of the present invention is to minimize the amount of antibiotics in the body when the feed composition is used in poultry and livestock, and to improve the metabolism by the health function of silver nano inorganic salts to reduce the content of cholesterol and triglycerides to reduce the content of meat with an appropriate protein content It is to provide a feed composition that can be provided. In addition, in the case of meat produced by ingesting the feed of the present invention, it is possible to provide a meat intake to the health functionalities of the silver nano material contained in the meat.

Claims (3)

0.01 to 3 parts by weight of silver nano-coated inorganic salts and 0.001 to 0.1 parts by weight of antibiotics based on 100 parts by weight of feed grains containing one or more sugars, proteins and lipids selected from corn, soybean, soybean meal, wheat, soybean, barley and rice bran. In the feed composition comprising, the silver nano-coated inorganic salts are 0.01 to 0.5 parts by weight of silver nano particles of particle size of 1 to 50 nm based on 1 part by weight of one or more inorganic salts selected from sodium chloride, calcium chloride, potassium chloride, magnesium chloride, sodium sulfate Feed composition, characterized in that prepared by vapor deposition delete delete