KR100753863B1 - Composite that have improvement effect vitality of hair - Google Patents

Abstract

A composition for preventing hair loss and improving vitality of hair and a preparation process thereof are provided to inhibit side effects on the scalp, activate hair cells by promoting blood circulation of the scalp and supplying nutrients to the scalp, and assist metabolism of the hair and anti-oxidative function of the scalp. The composition for preventing hair loss and improving vitality of hair comprises a first mixture containing 10 wt.% of Codonopsis pilosula NANNF extract, 10 wt.% of Carthamus tinctorius L. extract, 12 wt.% of Zanthoxylum schinifolium extract, 12 wt.% of Cndium monnieri L. extract, 14 wt.% of Cnidium officinale extract, 6 wt.% of green tea leaf extract, 6 wt.% of pomegranate extract, 8 wt.% of pine leaf extract, 2 wt.% of red ginseng extract, 2 wt.% of ginseng extract and 18 wt.% of Angelica gigas Nakai extract, and a second mixture containing 91 wt.% of purified water and 9 wt.% of vitamin agent containing nicotinic acid amide and acetic acid tocopherol in a mixing ratio of 4:6.

Description

Composition having a hair loss prevention and wool activity auxiliary function and a method for producing the composition {Composite that have improvement effect vitality of hair}

The present invention relates to a composition having a hair loss prevention and wool activity auxiliary function, and a method for producing the composition, in particular, natural herbal raw material as a main ingredient, there is no side effect of scalp, the ingredients contained in each raw material nourish blood circulation and scalp Promotes cell activation through stimulation of hair cells, thereby helping to metabolize hair, help antioxidants of the scalp to inhibit hair loss as much as possible, and at the same time prevent hair loss and have a secondary function to help wool. It relates to a composition having a wool activity auxiliary function and a method for producing the composition.

The hair of the human body is about 100,000 to 150,000 pieces, and each hair grows and falls out through an anagen, a catagen, and a telogen at different cycles.

This cycle is repeated over three to six years, with the result that on average 60 to 100 hairs fall out normally.

In general, alopecia refers to a shortening of hair growth in the growth phase and more hair in the degenerative or resting phase during this cycle, leading to an increase in the number of abnormal hair loss.

The causes of hair loss include abnormalities in the endocrine system such as hormonal imbalance, autonomic nervous system, poor blood circulation, excessive male hormone action, excessive sebum secretion, dandruff and other bacteria, scalp hypoplasia, nutritional deficiency of hair roots, allergies, Bacterial infections, genetic factors, aging and stress are being discussed.

However, to date, no clear cause of hair loss is known, and in recent years, the hair loss population has increased due to changes in dietary life and increased stress due to social environment, and recently, due to shampoo, mousse, perm, dyeing, and dry heat. Hair and scalp injuries act as a major cause of hair loss, and hair loss is significantly increasing in young people in their 20s and 30s, and hair loss in women is also gradually increasing.

Efforts have been made to treat alopecia around the world, and to date, researches on pharmacotherapy such as female hormones, blood circulation promoters, vitamin E, vitamin B2 composition, carotene dissolving agents, fungicides, and hair transplantation methods have been conducted.

Propecia, marketed by the US drug company Merck, has reported 68% of hair loss prevention and 66% of the group taking the hair, but these treatments were effective at the time of administration. The drug effect is effective, and after a few months of taking the drug, there was a problem that hair loss proceeds again like a non-administrator, and the price was so expensive that it was very difficult for general consumers to use, and side effects such as decreased libido and erectile dysfunction when taken There was a big problem with this.

In addition, Pharmacia & Upjohn has developed Minoxidil formulations for a long time and used it to treat blood pressure and hypertension. This product is made with 2% minoxidil as a hair regrowth and released under the name of Rogaine.When the patent of minoxidil has expired, other companies made similar products and started selling them at low prices. I make it and sell it.

However, the minoxidil preparation has been found to be unsuitable for long-term use due to side effects such as dry scalp, erythema irritation symptoms, allergic contact dermatitis, facial hypertension and vasodilation, ie deprivation due to antihypertensive action, hypotension, tachycardia. .

As described above, most of the conventional compositions having a hair loss function do not have sufficient effects on conventional hair loss prevention and hair growth, and due to the use of an inappropriate concentration of hormone, inflammation of the skin causes hair loss to be more severe. Has many problems with biosafety.

Therefore, the present invention for solving the above problems as the first mixture 10% by weight, Salvia extract 10% by weight, safflower extract, 12% by weight acid extract, 12% by weight of filamentous extract, 14% by weight Cheongung extract, green tea leaf extract 6% %, Pomegranate extract 6% by weight, pine needle extract 8% by weight, red ginseng extract 2% by weight, ginseng extract 2% by weight, sugar extract 18% by weight as a second mixture, purified water 91% by weight, nicotinic acid amide and acetic acid It is provided by mixing 9% by weight of the vitamin agent consisting of tocopherol, and by mixing the first mixture and the second mixture in a ratio of 4: 6, there is no side effect of scalp using the natural herbal raw material as a main material, contained in each raw material Nutrients to nourish blood circulation and scalp to stimulate cell activation through stimulation of hair cells, thereby helping to metabolize hair and help antioxidants to scalp A it is a while significantly suppressed at the same time preventing hair loss secondary to have a function to assist in wool and wool production process of a composition having an active auxiliary functions and the composition for the purpose of providing.

The present invention for achieving the above object

According to claim 1,

As the first mixture, 10% by weight of red ginseng extract, 10% by weight of safflower extract, 12% by weight of acid extract, 12% by weight of filamentous extract, 14% by weight of cheonung extract, 6% by weight of green tea leaf extract, 6% by weight of pomegranate extract, pine needle extract 8 Wt%, 2% by weight of red ginseng extract, 2% by weight of ginseng extract, and 18% by weight of Angelica extract, are prepared by mixing 91% by weight of purified water as a second mixture, 9% by weight of a vitamin agent consisting of nicotinic acid amide and tocopherol acetate And mixing the first mixture and the second mixture in a ratio of 4: 6.

According to claim 2,
Salvia extract 10 wt%, Safflower extract 10 wt%, Sancho extract 12 wt%, Casualty extract 12 wt%, Cheongung extract 14 wt%, Green tea leaf extract 6 wt%, Pomegranate extract 6 wt%, Pine needle extract 8 wt%, Red ginseng A first process of preparing a first mixture by mixing 2% by weight of extract, 2% by weight of ginseng extract, and 18% by weight of Angelica extract;
A second process of preparing a second mixture by mixing 91 wt% of purified water and 9 wt% of a vitamin agent consisting of nicotinic acid amide and tocopherol acetate;

A third process of mixing the first mixture and the second mixture in a ratio of 4: 6 to complete the composition; Characterized in that configured.

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Hereinafter, preferred embodiments of the present invention will be described.

The present invention is a natural herbal raw material as a main ingredient to apply to the scalp without side effects, while improving the blood circulation inside the scalp to provide nutrition through the stimulation of hair cells, thereby activating the metabolism of the hair, The antioxidant properties of the scalp help to improve the scalp environment and provide a composition that assists the activation of wool while inhibiting hair loss as much as possible.

The composition of the present invention

As the first mixture, 10% by weight of red ginseng extract, 10% by weight of safflower extract, 12% by weight of acid extract, 12% by weight of filamentous extract, 14% by weight of cheonung extract, 6% by weight of green tea leaf extract, 6% by weight of pomegranate extract, pine needle extract 8 Wt%, 2% by weight of red ginseng extract, 2% by weight of ginseng extract, and 18% by weight of Angelica extract, are prepared by mixing 91% by weight of purified water as a second mixture, 9% by weight of a vitamin agent consisting of nicotinic acid amide and tocopherol acetate And mixes the first mixture and the second mixture in a ratio of 4: 6.

The composition is added 0.7 to 1.0% by weight of preservatives and spices to have a fragrance while suppressing the deterioration of natural herbal ingredients.

Salvia extract, safflower extract, sancho extract, filamentous extract, Cheongung extract, green tea leaf extract, pomegranate extract, pine needle extract, red ginseng extract, ginseng extract, Angelica extract, which forms the first mixture, add water and Collect.

The characteristics of the material constituting the first mixture are as follows.

* Dansam: Dansam is native to China and grows in the mountains. It is 40 ~ 80cm high and has a lot of hairs. Stems are monadic, purplish, straight, and branched. Roots are red, leaves are opposite each other, with long petiole with hole leaf or two pinnate leaves. Small leaves are 1 ~ 3 pairs, egg-shaped or lancet-shaped, bottom is heart-shaped, pointed tip and dull sawtooth at edge. Flowers bloom purple in May-June and layered at the end of stems. There are dense hairs on the stalk. A bract is a string or lanceolate, shorter than a small peduncle. The sepal is 8 ~ 10cm long, tubular, and purple. Corolla is lip shape, 2 ~ 2.5cm long, and lower lip petal is divided into 3 branches. The middle of the split pieces is the longest, digs out and has jagged teeth on the edge. The stamen comes out of the flower long. Fruits are 2-3, with rounded oval. The roots have a peculiar smell and a bit bitter taste. It is used for women's menstrual disorders, menstrual pain and postpartum abdominal pain, and it is used to treat hemolytic cardiac pain and bruises, and for insomnia skin rash.

* Cheongung: Cheongung is native to China and is grown as a medicinal object. It is 30 ~ 60cm high, hollow inside, and its branches diverge somewhat. The leaves are alternated and the pinnate leaf is 2 times and 3 times. The forked pieces are egg-shaped lanceolate with somewhat deep tooth. Root leaves and bottom leaves have long petioles and the bottom leaves are leaflets to cover the stems.

Flowers blossom in August and white, forming a double inflorescence. Petals 5, dried inwards, 5 stamens, 1 pistil. The guns and rifle guns are 5-6 pieces each and are in the shape of a string. Fruits are open but not mature. Nodes in the ground look like lumps 5-10 cm long and 3-5 cm in diameter with a strong fragrance.

In oriental medicine, the root stem is effective for soothing, analgesic, and tonic, and is used for headache, anemia, and host disease. It is a fragrant plant and is stored in wardrobe to prevent moths in the private sector. It is said that the regeneration of celestial boiled water on the roots of dying pines is excellent for cell regeneration.

* Sancho: Sancho is also called Cheoncho, Scented Candle, Yacho, Scented Oil, Branch Tree, Bundi Tree, Minchocho, Sangcho, Nacho, etc .. many. Leaves are radix one-time upper lobe, 奇數 一 回 羽 牀 複葉, 1 ~ 21 twigs, oval lanceolate, narrowing in end, ending with uropod. The leaves are 1.5 ~ 5cm long, with wave-shaped serrates on the edges, and spines on the leaf axis.

Flowers bloom in August-September, flowers are light green, have no fragrance, and hang on the end of stems or stems 5 ~ 10cm long. In October, the Zucchini leaves are dark brown with blackish seeds. In Korea, young stems and bud leaves are eaten with unripe fruit and jangchae (醬菜). Fruits are squeezed and are widely used as lighting and flavorings.

Sancho is used for industrial, wheat, and medicinal purposes. For folk remedies, dried fruit, bark, and leaves are dried, kneaded with flour and candle, and spread on sturdy paper or cloth, and are good for mastitis, boil, and bruise. In any part of the sancho to wash with decoction is effective, and the root is burned in fire and used as a som (燒 末). Drinking decoctions will stop headaches and coughs and bite your mouth to stop the pain of tooth decay.

In Chinese medicine, boiling water or boiling water is used to remove limbs. It is also good for wind and wet rain. Sancho is a mild, irritating insecticide. It is dry, dry, dry, and diuretic. It is said to work, fruit, bark, leaves and debris to remove the residue, and further boiled and made like syrup, and then take a tablespoon three times a day with a small spoon is said to be effective in edema.

In October, the temple collects slightly less fruit and simmers the soy sauce several times. Sancho soy sauce is especially good as a side dish.

Safflower: Safflower has been used as a natural pigment since ancient times, and it is known to have a mysterious effect on broken bones. Platinum (Pt), a metal, can be a deadly poison for humans and animals. The organic platinum in safflower seed has excellent anti-cancer activity, cures fractures, porosity, and extends the lifespan of people.

The main components of safflower oil are linoleic acid and glyceride, which also contain 90 ml of vitamin E, which inhibits aging. In addition, safflower is warm, weak, and reigns blood, so it is used as a blood, pain and medicine. Flowers are bleeding at the same time, but at the same time live blood (blood), blood (보).

Applying these safflower extracts to the scalp improves blood circulation.

* Angelica (當歸): Angelica grows in the mountains and fields are also grown. The leaves and stems are eaten as herbs in early spring, and the roots are dried and used as medicine. A lot of flesh and not thin is good.

Angelica lowers all parasitic diseases, blood clots and pathologies, curbs hardened blood, and gives rise to new blood. It is good for symptom of condensation in the chest, denitrification of woman and pregnancy. It is good for the bad blood and injured by iron, so that the blood clot is better and the abdominal pain is sore and cold due to dysentery. . If you use the head of the donkey to bleed through the blood and stop the bleeding by using the roots. If you write the whole, the blood on the one hand, and the blood stops on the other hand to even the blood. Angelica is the most commonly used medicine because of its strong blood action.

If you apply this donkey to the scalp can be expected to improve the blood circulation inside the scalp.

* Pomegranate: Pomegranate is 6 ~ 8cm in diameter, round shape. It is covered with hard yellowish skin and there are many seeds in the pulp. You can eat about 20%, but the flesh is sweet and sour taste and the peel is used as medicine. The varieties are divided into sweet persimmon and acidic acid. Its origin is West Asia and northwestern India, and Korea is believed to have come from China in the early days of Goryeo. Currently grown in garden and fruit trees in central and southern regions.

The main ingredient is sugar (glucose, fructose), which takes about 40%, and the valuable acid contains about 1.5% citric acid, which tastes sour. It also contains water-soluble vitamins (B1, B2, and niacin), but they are low in amount. The shell contains tannins and the seeds contain natural plant estrogens that are good for menopausal disorders.

Hypertension in both berries and bark. It is good for preventing atherosclerosis, and it is effective for women's diseases and swelling. In particular, when it is dysentery, it has excellent medicinal effects and contains volatile alkaloids. Fruit juices can be used to make drinks and sweets by immersing fruit juices and making concentrated juices. It can also be mixed with olive oil to make a good constipation oil.

Green tea leaf: Epicatechin-3-gallate and epigallocatechin-3-gallate selectively inhibit the 5 alpha recuctase enzyme, and catechins extracted from green tea leaves have anti-androgen properties and are effective in preventing hair loss. A study from the University of Chicago, USA, has been published, and it also contains high amounts of catechin, a tannin component.

Hair loss or discoloration is caused by the oxidation of unsaturated fatty acids ingested in the body, resulting in the destruction of cell membranes in cell tissues. Catechin in green tea leaves inhibits lipid peroxidation because vitamin C increases antioxidant power. Suppress In addition, green tea contains alkaline minerals, vitamin B group and C group, giving skin elasticity and inhibiting the production of melanin pigment to make skin fine.

Applying green tea leaf extract to the scalp will increase the antioxidant power of the hair root.

Ginseng: Ginseng contains saponin glycosides (saponin glycosides), ginsenosides, steroids, vitamin B group, and choline. In general, the ginseng's medicinal effects, which are recognized in Korean medicine, can be summarized as tonic, stiffness, health, correction, soothing, and nourishment, and used as an activator to decrease metabolic function due to functional weakness of the stomach.

Therefore, when ginseng extract is applied to the scalp, it contributes to the activity of the weak cells in the scalp.

Casualties: Casualties are also known as snakedorats. It grows in the grass and is 30 ~ 70cm high. The whole hair is broken and the stem stands straight. The leaves are alternated, and the leaves with three small leaves are divided into two pieces. The leaves are 5 ~ 10cm long. The tip is pointed and the bottom of the petiole wraps around the main stem like a leaf leaf. Small leaves are oval-shaped, and have sharp sawtooth. Flowers are white in June-August and hang in the shape of branches and stems in a double inflorescence. Dissipation is 5-9, 1 ~ 3cm long, with 6 ~ 20 flowers. There are 4 ~ 8 guns, row shape, about 1cm long, and small guns are lined and attached to the peduncle. Fruits are dividing, egg-shaped, 2.5 ~ 4mm long. Run 4 to 10 pieces each with short spiny hairs that stick well to other objects.

Young shoots are eaten as herbs, and fruits are used as astringents, antifoams, and insecticides.

* Red ginseng: Red ginseng has a sedative and arousing effect on the central nervous system. It has a protective effect on hypertension or arteriosclerosis by acting on the circulatory system. At the same time, hematopoietic effect (造血 作用) and blood sugar (血糖 値) lowers, protects the liver, acts on the endocrine system indirectly effective on sexual behavior and reproductive effects, anti-inflammatory And anti-tumor effect (項 腫 瘍 作用), the protective effect against radiation, protects and softens the skin. The most important of the effects of red ginseng is the adaptogen effect, which increases the ability of the body to defend against various diseases such as lacrimal disease and various stresses from the surrounding environment. It is scientifically proven.

Therefore, when red ginseng extract is applied to the scalp, the hair root cells have a protective ability against stress and the like, as well as an effect of improving blood circulation by hematopoiesis.

* Pine needles: Dongbobom says that if you reproduce pine needles for a long time, they will not grow old, become vigorous, have black hair, and do not know cold or hunger. Hyangyakbangbang introduces the effect that the pine needles are cut into small pieces like millet and shredded into boards, making the body warm and deceived and not cold.

One of the key components of pine needles is the terpene, a volatile component that flies into the air. Currently, more than 40 species of terpenes in pine needles have been identified. The most numerous are alpha-pinene, beta-pinene, beta-phellandrene, beta-cayfilene, myrcene, campain, alpha-terpinolene and the like. Hardwoods also have unique terpenes, but they have terpenes that are much richer. On the one hand, pine needles are bitter, but the nature is warm and non-toxic, mainly acts on the heart and parenteral. Recent pharmacological experiments in China and North Korea have been shown to promote the redox process of biological tissues, eliminate astringent inflammation, and stop blood.

Accordingly, when the pine needle extract is applied to the scalp, it can be expected to activate the cell metabolism in the scalp by the redox promoting function of biological tissues.

As described above, the characteristics of salviae, safflower, sancho, casualty, cheongung, green tea leaves, pomegranate, pine needles, red ginseng, ginseng, and Angelica, etc., which form the first mixture of the present invention, have been described. Cell regeneration function, improving blood circulation of safflower, improving blood circulation of donkey, 'antioxidative activity of hair root' of green tea leaves, cellular activity of ginseng, improving blood circulation of red ginseng, and improving cell metabolism of pine needles The scalp is healthy and helps to suppress hair loss while providing a secondary function of wool activity.
In addition, since the vitamin constituting the second mixture is generally known image component, further description thereof will be omitted.

Referring to the composition manufacturing method of the present invention is as follows.

First, 10% by weight of Salvia extracts, 10% by weight of safflower extracts, 12% by weight of acid extract, 12% by weight of filamentous extract, 14% by weight of Cheongung extract, 6% by weight of green tea leaf extract, 6% by weight of pomegranate extract, 8% by weight of pine needle extract , Red ginseng extract 2% by weight, ginseng extract 2% by weight, Angelica extract 18% by weight to prepare a first mixture.

The first mixture consists only of pure herbal medicine.

Then, a second mixture is prepared by mixing 88 to 91% by weight of purified water, 6 to 9% by weight of a vitamin agent consisting of nicotinic acid amide and tocopherol acetate.

3. 결과 : 본 발명의 조성물을 두피에 바른 후 15일이 지난 후 16명의 두피환경이 53%로 개선되기 시작하였고, 75일이 경과한 이후에는 30명 전원의 두피환경이 개선됨을 확인할 수 있었고, 이러한 두피환경 개선에 의하여 탈모를 줄여주게됨을 확인할 수 있었다. 또한 두피환경의 개선으로 인해 대다수의 대상자에게서 연모 및 발모가 진행되는 것을 확인할 수 있었다. As described above, when the first mixture and the second mixture are made, the first mixture and the second mixture are mixed at a ratio of 4: 6, and the first and second mixtures are mixed with 0.7 to 1.0 weight of preservatives and spices. The composition of the present invention is completed by adding% so that the fragrance is suppressed while the alteration of natural herbal materials is suppressed.
◆ Clinical Trial Data ◆
1. Subjects and ranges: 30 males and 15 males and females were selected for 120 days (4 months). The subjects were those who had undergone hair loss for 2 to 6 years, and their age was limited to 25 to 55 years. .
2. Clinical Result Table

3. Results: After applying the composition of the present invention on the scalp, after 15 days, the scalp environment of 16 people began to improve to 53%, and after 75 days, the scalp environment of all 30 patients improved. In addition, it was confirmed that hair loss was reduced by improving the scalp environment. In addition, due to the improvement of the scalp environment, it was confirmed that hair growth and hair growth progressed in the majority of the subjects.

As described above, the present invention provides 10% by weight of Salvia extract, 10% by weight of safflower extract, 12% by weight of red pepper extract, 12% by weight of filamentous extract, 14% by weight of green leaf extract, 6% by weight of green tea leaf extract, and pomegranate. 6% by weight of extract, 8% by weight of pine needle extract, 2% by weight of red ginseng extract, 2% by weight of ginseng extract, 18% by weight of Angelica extract, as a second mixture of 91% by weight of purified water, nicotinic acid amide and tocopherol acetate It is provided by mixing 9% by weight of the vitamin agent, and by mixing the first mixture and the second mixture in a ratio of 4: 6, there is no side effect of scalp using a natural herbal raw material as a main material, the ingredients contained in each raw material It provides nutrition to the blood circulation and scalp to promote cell activation through stimulation of hair cells, thereby helping to metabolize the hair, and to help hair loss by oxidizing the scalp. Inhibition while at the same time it can be expected the effect of providing a hair loss prevention to have a secondary function to assist in wool and wool production process of a composition having an active auxiliary functions and the composition.

Claims (2)

As the first mixture, 10% by weight of red ginseng extract, 10% by weight of safflower extract, 12% by weight of acid extract, 12% by weight of filamentous extract, 14% by weight of cheonung extract, 6% by weight of green tea leaf extract, 6% by weight of pomegranate extract, pine needle extract 8 Wt%, 2% by weight of red ginseng extract, 2% by weight of ginseng extract, and 18% by weight of Angelica extract, are prepared by mixing 91% by weight of purified water as a second mixture, 9% by weight of a vitamin agent consisting of nicotinic acid amide and tocopherol acetate And a first mixture and a second mixture in a ratio of 4: 6. Salvia extract 10 wt%, Safflower extract 10 wt%, Sancho extract 12 wt%, Casualty extract 12 wt%, Cheongung extract 14 wt%, Green tea leaf extract 6 wt%, Pomegranate extract 6 wt%, Pine needle extract 8 wt%, Red ginseng A first process of preparing a first mixture by mixing 2% by weight of extract, 2% by weight of ginseng extract, and 18% by weight of Angelica extract; A second process of preparing a second mixture by mixing 91 wt% of purified water and 9 wt% of a vitamin agent consisting of nicotinic acid amide and tocopherol acetate; A third process of mixing the first mixture and the second mixture in a ratio of 4: 6 to complete the composition; Method for producing a composition having a hair loss prevention and wool activity auxiliary function, characterized in that consisting of.