KR100551778B1 - 티오펜 레티노이드 - Google Patents

티오펜 레티노이드 Download PDF

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Publication number
KR100551778B1
KR100551778B1 KR1020037000289A KR20037000289A KR100551778B1 KR 100551778 B1 KR100551778 B1 KR 100551778B1 KR 1020037000289 A KR1020037000289 A KR 1020037000289A KR 20037000289 A KR20037000289 A KR 20037000289A KR 100551778 B1 KR100551778 B1 KR 100551778B1
Authority
KR
South Korea
Prior art keywords
hydrogen
tetramethyl
alkyl
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020037000289A
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English (en)
Korean (ko)
Other versions
KR20030040350A (ko
Inventor
클라우스미카엘
라피에르장-마르크
Original Assignee
에프. 호프만-라 로슈 아게
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Application filed by 에프. 호프만-라 로슈 아게 filed Critical 에프. 호프만-라 로슈 아게
Publication of KR20030040350A publication Critical patent/KR20030040350A/ko
Application granted granted Critical
Publication of KR100551778B1 publication Critical patent/KR100551778B1/ko
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
KR1020037000289A 2000-07-10 2001-06-30 티오펜 레티노이드 Expired - Fee Related KR100551778B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00114767.7 2000-07-10
EP00114767 2000-07-10
PCT/EP2001/007506 WO2002004439A2 (en) 2000-07-10 2001-06-30 Thiophene retinoids

Publications (2)

Publication Number Publication Date
KR20030040350A KR20030040350A (ko) 2003-05-22
KR100551778B1 true KR100551778B1 (ko) 2006-02-13

Family

ID=8169205

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037000289A Expired - Fee Related KR100551778B1 (ko) 2000-07-10 2001-06-30 티오펜 레티노이드

Country Status (12)

Country Link
US (1) US6403810B2 (enExample)
EP (1) EP1301505A2 (enExample)
JP (1) JP2004502767A (enExample)
KR (1) KR100551778B1 (enExample)
CN (1) CN1219777C (enExample)
AR (1) AR029572A1 (enExample)
AU (2) AU8961901A (enExample)
BR (1) BR0112328A (enExample)
CA (1) CA2414936C (enExample)
MX (1) MXPA03000222A (enExample)
WO (1) WO2002004439A2 (enExample)
ZA (1) ZA200210049B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
US7476673B2 (en) * 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
US7250414B2 (en) * 2004-03-11 2007-07-31 Theravance, Inc. Diphenylmethyl compounds useful as muscarinic receptor antagonists
US20060161076A1 (en) * 2005-01-06 2006-07-20 Diamics, Inc. Systems and methods for collection of cell clusters
US20060189893A1 (en) * 2005-01-06 2006-08-24 Diamics, Inc. Systems and methods for detecting abnormal cells
US7781187B2 (en) * 2005-12-30 2010-08-24 Corning Incorporated Fluorescent dyes
WO2008057930A2 (en) * 2006-11-02 2008-05-15 Aestus Therapeutics, Inc. Methods of treating neuropathic pain with retinoic acid receptor agonists
WO2025109225A1 (en) 2023-11-24 2025-05-30 Etherna Immunotherapies Nv Method for reducing dsrna formation during ivt

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123469A (en) 1977-06-30 1978-10-31 International Flavors & Fragrances Inc. Process for production of bicyclic compounds
US5324840A (en) * 1992-06-11 1994-06-28 Allergan, Inc. Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects
US5455265A (en) * 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
US5399586A (en) 1993-03-11 1995-03-21 Allergan, Inc. Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity
US5475022A (en) * 1993-10-18 1995-12-12 Allergan, Inc. Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity
FR2743560B1 (fr) * 1996-01-17 1998-04-03 Europ De Bioprospective Centre Derives polycycliques aromatiques de type retinoide, leur procede de preparation et leur utilisation pour la fabrication de compositions pharmaceutiques et cosmetiques
FR2753091B1 (fr) 1996-09-09 2001-03-16 Oreal Utilisation d'un agoniste des recepteurs des retinoides de type rxr pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute

Also Published As

Publication number Publication date
WO2002004439A3 (en) 2002-09-26
KR20030040350A (ko) 2003-05-22
US6403810B2 (en) 2002-06-11
MXPA03000222A (es) 2003-06-06
AU2001289619B2 (en) 2006-07-13
BR0112328A (pt) 2003-07-22
CA2414936C (en) 2006-12-05
AR029572A1 (es) 2003-07-02
WO2002004439A2 (en) 2002-01-17
ZA200210049B (en) 2004-03-11
AU8961901A (en) 2002-01-21
CN1441798A (zh) 2003-09-10
JP2004502767A (ja) 2004-01-29
EP1301505A2 (en) 2003-04-16
CN1219777C (zh) 2005-09-21
CA2414936A1 (en) 2002-01-17
US20020019438A1 (en) 2002-02-14

Similar Documents

Publication Publication Date Title
AU772551B2 (en) New selective retinoid agonists
EP1280757B1 (en) New gamma selective retinoids
KR100551778B1 (ko) 티오펜 레티노이드
US6479670B1 (en) Selective retinoid acid receptor agonists
AU2001289619A1 (en) Thiophene retinoids

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