KR100545381B1 - Deodorants, Foods having deodorants and deodorizing composition - Google Patents

Abstract

The present invention relates to a deodorant, a food and a deodorant composition containing the same, and more particularly, a high-safety plant of the genus Rosaceae, a eucalyptus and guava, a noble family of high-safety plants that can be used safely for food. A deodorant which selectively contains extracts such as the noble tree, the hibiscus hamamelis and the dolmulsu (Red pheasant), as well as the active ingredient, and is highly deodorized against allylmethyl monosulfide, a monosulfide compound. It relates to a deodorant having an effect, to a food and a deodorant composition containing the same.

Deodorant, Monosulfide, Allylmethyl Monosulfide

Description

Deodorants, Foods having deodorants and deodorizing composition

The present invention relates to a deodorant, a food and a deodorant composition containing the same, and more particularly, a high-safety plant of the genus Rosaceae, a eucalyptus and guava, a noble family of high-safety plants that can be used safely for food. A deodorant which selectively contains extracts such as the noble tree, the hibiscus hamamelis and the dolmulsu (Red pheasant), as well as the active ingredient, and is highly deodorized against allylmethyl monosulfide, a monosulfide compound. It relates to a deodorant having an effect, to a food and a deodorant composition containing the same.

Bad breath is generally classified into physiological bad breath, bad breath caused by eating and bad breath caused by disease. For example, eating bad foods such as garlic can cause bad breath. In general, allyl mercaptan and diallyl disulfide are detected in the bad breath immediately after ingesting garlic, but the odor gradually decreases over time and is not detected the next day.

However, by research by Johann Taucher, monosulfide compounds, allylmethylmonosulfide, dimethylmonosulfide, and ketone compounds, acetone, are detected during exhaled breath after garlic intake and are detected at high concentrations even after 24 hours. The fact is known [J. Agric Food Chem 44 (12), 3778-3782 (1996).

Allylmethyl monosulfide has a significantly higher concentration when breathing out garlic than dimethyl monosulfide. In addition, the smell after ingestion of garlic has the same smell quality as allylmethyl monosulfide, and different from the smell of dimethyl monosulfide. Acetone is irrelevant to the odor when breathing after garlic intake because the level of odor identification (100 ppm) is 20 times higher compared to the maximum concentration (5 ppm) measured during exhaled breath measured in the literature.

Therefore, allylmethyl monosulfide is a major cause of bad breath after garlic ingestion, and deodorizing the odor derived therefrom is effective for removing metabolic odor of garlic.

Thiol compounds, such as allyl mercaptan and methyl mercaptan, exhibit high reactivity with thiol (-SH) groups present in the molecule. It has been found that they are deodorized by mechanisms such as kel addition reactions and 3) coupling reactions with polyphenol compounds.

However, allylmethyl monosulfide is a sulfur compound having a bad smell like a thiol compound, but since it does not have a highly reactive functional group in its molecule, it is generally considered to be less reactive than a thiol compound such as methyl mercaptan, which is a bad breathing substance, and thus is difficult to deodorize. have.

Among the previously reported deodorant materials, there are few substances which exhibit deodorizing effect against monosulfide compounds such as allylmethyl monosulfide, and chlorophyll compounds having a high effect on the deodorization of thiol compounds [Monthly Food Chemical No. 11 106-110 ( 1995) and green tea extract [Japanese Patent No. 1330998] are also known to have insufficient deodorizing effects on allylmethyl monosulfide. As such, monosulfide compounds such as allylmethyl monosulfide have a deodorizing mechanism that differs greatly from thiol compounds such as allyl mercaptan and methyl mercaptan. There are many.

It is known that benzaldehyde and cinnamon aldehyde react with monosulfide as a component derived from natural products (臭氣 臭氣, 13, 63, 19-28 (1985)), but these aldehydes have a unique strong fragrance. The practical use is limited, and development of a highly practical and safe deodorant for the monosulfide compound is required.

As a deodorant component derived from natural products, the rosewood raspberry plant has been found to have a deodorizing effect on a methyl mercaptan, a thiol compound, and a trimethylamine, a nitrogen compound (Japanese Patent Publication No. 1823565). Deodorizing compositions are also disclosed as deodorizing materials for methyl mercaptan (Japanese Patent Laid-Open No. 05-269187). However, in both cases described above, the deodorizing effect on allylmethyl monosulfide, which is a monosulfide compound, has not been found.

Extracts from eucalyptus are likewise disclosed as deodorants for hydrogen sulfide, ammonia, amines, mercaptans and nicotine [Japanese Patent Publication No. 60-261458], but the deodorizing effect on allylmethyl monosulfide, a monosulfide compound, has been found. none.

Although the effects of decayed meat pieces and deodorization in animal breeding rooms are known as air purifiers for noble trees (Japanese Patent Laid-Open No. 51-27882), these odors are generally hydrogen sulfide and mercaps generated by decomposition of animals and plants. Sulfur compounds such as carbons, nitrogen compounds such as ammonia and amines, and lower fatty acids are the main causes, and the deodorizing effect on allylmethyl monosulfide is not known.

Extracts obtained from Hamamelis are disclosed as deodorants for axillary odor, foot odor, body odor and human odor of the human body [Japanese Patent Laid-Open No. 2000-186025], but the above-mentioned odor components include lower fatty acids including isogyl acetate and Aldehydes are dominant and there are no reports of allylmethyl monosulfide. Therefore, the deodorizing effect on allylmethyl monosulfide by the Hamamelis derived component is not known.

There is no report on the deodorizing effect of allylmethylmonosulfide on guavas and red ginseng.

The present inventors have made efforts to solve the above problems, attention to the deodorizing action of natural extracts such as herbals and herbs that have been used since ancient times because of the high safety and no side effects to the human body, in particular, allylmethyl monosulfide Efforts have been made to develop deodorant components that have a deodorant effect on. Thus, the extracts obtained from rosemary raspberry, eucalyptus and guava of papaveraceae, elderwood of the genusaceae, hamamelis of the evergreen family, and Rhodiola sachalinensis of Sedum (Pheasant) have allylmethyl monosulfide deodorizing activity. Knowing the facts completed the present invention.

Therefore, the present invention is a deodorant containing a high-safety natural plant extract that can be used safely in food as an active ingredient, a deodorant exhibiting a strong deodorant effect on allylmethyl monosulfide, a monosulfide compound, and a food and deodorant containing the same The purpose is to provide a composition.

The present invention relates to a plant of the genus Rubus, Eucalyptus globulus and Psidium guajava, Myrica rubra of the genus Camellia, Hamamelis of the evergreen family It is characterized by an allyl methyl monosulfide deodorant comprising one or two or more extracts selected from Rhodiola sacra of Rhodiola sacra.

The present invention also includes a food and deodorant composition containing the deodorant for allylmethyl monosulfide.

The present invention will be described in detail as follows.

The present invention is a deodorant containing a high-safety natural plant extract that can be used safely in food as an active ingredient, a deodorant having a high deodorizing effect against allylmethyl monosulfide, which is a monosulfide compound It relates to food and deodorant composition.

Rosemary raspberry (Rubus Idaeus), blackberry (Rubus fruticosus, Rubus allegheniensis), lycheeberry (Rubus trifidus), Rubsu suavissimus, etc. can be used, and eucalyptus and guava as a plating herb Can be used.

Eucalyptus and guava of the rose family Raspberry and Platinum can be used skin, leaves, pulp, fruit, wood, bark, root and the like, and preferably those dried.

Each part of the plant can be used as a noble tree and a hamamelis, but it is most preferable to dry the bark, and in the case of Honggyeongcheon, each part of the plant can be used as well, but it is most preferable to use the root and root of dried plants. Do.

The method for obtaining the extract of the plant used as the active ingredient of the deodorant composition of the present invention is not particularly limited, but the plant is ground by appropriate grinding means, and the extract is prepared by a method such as solvent extraction. As the extraction solvent, one or two or more selected from lower alcohols such as water, methanol, ethanol, n-propanol and n-butanol, ether, chloroform, ethyl acetate, acetone, glycerin and propylene glycol can be used and mixed. Alternatively, it is preferable to use a hydrophilic organic solvent, and the extract of the present invention is most preferably used in combination with water and ethanol in terms of safety as an extraction solvent when used by humans or as a food.

As extraction conditions, although extraction is possible at high temperature, room temperature, and low temperature, it is preferable to extract about 50 to 90 degreeC for 1 to 5 hours. The obtained extract is filtered, the extractant is distilled off, and then concentrated or lyophilized under reduced pressure. In addition, fractions of these extracts can be used by organic solvents, column chromatography, and the like.

In addition, the deodorant for allylmethyl monosulfide of the present invention is excellent in flavor and taste and high in safety. For example, deodorant compositions such as toothpaste and deodorant spray, or chewing gum, candy, tablets, gummi jelly, chocolate, Biscuits, snacks such as snacks, ice cream, sherbet, frozen desserts such as ice cream, beverages, bread, hot cakes, dairy products such as dairy products, hams, sausages, meat products such as fish cakes, cheeks, side dishes, puddings, soups, soups, etc. It can mix | blend with food and can use routinely.

The addition amount is 0.001% by weight of the dry extract to the food or deodorant composition, preferably 0.01% by weight, when the addition amount of the dry extract is less than 0.001% by weight deodorizing effect is insignificant. In the case of application to food, it is preferable to add in an amount of 0.001 to 5% by weight, preferably about 0.01 to 1% by weight, in consideration of the palatability of the food.

In addition, the deodorant for allylmethyl monosulfide of the present invention can also be used in combination with other common deodorants such as cyclodextrin.

Rosemary raspberry plants (raspberries, blackberries, cucurbita, etc.) which are used as raw materials in the present invention are consumed as herbal teas or teas, and the fruits are edible, and also eucalyptus leaves, bark of bark, hamamelis bark and The roots and rhizomes of hongkyungcheon have been used for a long time as herbal medicines, food ingredients, herbal teas and food additives. Guava, which belongs to the plated Western family, is made from tea and made of tea in Japan. In tropical America, where it is widely distributed, the fruit is eaten as it is or used as a raw material for sake or juice.

Therefore, all of the plants used as raw materials of the present invention have been used for a long time as herbal medicines, food materials, herbal teas and natural additives, and allylmethyl monosulfide deodorant having an extract of these plants as an active ingredient and food and drink containing the same and There is no problem with regard to the safety of the deodorant composition.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the present invention is not limited by the following Examples.

Example 1

400 ml of water was added to 20 g of dried leaf powder of cucurbita and extracted by refluxing at 80 ° C. for 3 hours using a reflux condenser. The obtained extract was filtered, the solvent was removed, and lyophilized to obtain 4.6 g of the extract.

Example 2

400 ml of 50% ethanol is added to 20 g of guava leaf powder, it is connected by reflux condenser, and it extracts under reflux at 80 degreeC for 3 hours. The obtained extract was filtered, the solvent was removed, and lyophilized to obtain 4.1 g of the extract.

Examples 3-10 and Comparative Examples 1-4

In the same manner as in Example 1 or 2 and extracts of raspberry leaf, blackberry (Rubus fruticosus) leaf, lychee strawberry leaf, blackberry (Rubus allegheniensis) leaf, eucalyptus leaf, bark bark, hamamelis bark and red ginseng root As a comparative example, extracts of green tea leaves, rosemary leaves, comfrey leaves, and sage leaves were prepared. The raw materials used, the extraction solvents, and the yields are shown in Table 1 below.

Botanical name Extraction solvent yield(%) Example Raspberry Leaf water 17.4% Blackberry Leaf ¹⁾ water 17.4% Lycheeberry leaf water 16.7% Blackberry Leaf ²⁾ water 16.9% Cucumber Leaf water 23.1% Eucalyptus leaves water 18.0% Bark water 16.7% Guava leaves 50% ethanol 20.5% Hamamelis Bark 50% ethanol 16.8% Rhodiola root 50% ethanol 31.4% Comparative example Green tea leaves water 32.6% Rosemary Leaf water 17.2% Comfrey Leaf 50% ethanol 15.6% Sage leaves 50% ethanol 21.4% 1) Rubus fruticosus 2) Rubus allegheniensis

Experimental Example

10 mg of the extract of each plant prepared according to Examples 1 to 9 and Comparative Examples 1 to 4 was dissolved in 1 ml of 0.2 M phosphate buffer (pH 7.5) in a 30 ml Bayer bottle, followed by 1 ppm of allylmethyl monosulfide solution 0.25 ㎖ was added and the rubber stopper immediately mixed. Phosphate buffer was used alone as a control.

After shaking the mixture for 2 hours at 37 ° C, 100 µl of headspace gas was injected into the gas chromatograph and the peak height of allylmethyl monosulfide was measured. As a result, the amount of allylmethyl monosulfide was calculated by the calibration curve of the allylmethyl monosulfide previously prepared, the deodorization rate was obtained by the following formula, and the result is shown in Table 2 below.

Deodorization rate (%) = (C-S) / C × 100

Here, C is the concentration of allylmethyl monosulfide used in the control, S is the concentration of allylmethyl monosulfide when the plant extract is added.

Botanical name Extraction solvent Deodorization rate (%) Example Raspberry Leaf water 55% Blackberry Leaf ¹⁾ water 43% Lycheeberry leaf water 39% Blackberry Leaf ²⁾ water 40% Cucumber Leaf water 78% Eucalyptus leaves water 58% Bark water 61% Guava leaf 50% ethanol 35% Hamamelis Bark 50% ethanol 47% Honggyeongcheon Root 50% ethanol 59% Comparative example Green tea leaves water 21% Rosemary Leaf water 5% Comfrey Leaf 50% ethanol 8% Sage leaves 50% ethanol 3% Iron Chloropyrine Sodium - 3% 1) Rubus Fruticosus 2) Rubus allegheniensis

As shown in Table 2, iron chloropyrine, green tea leaf water extract, rosemary water extract, comfrey leaf 50% ethanol extract, sage leaf 50% ethanol extract, which are generally known as a deodorizing effect, were evaluated. The rate was 21% of green tea, and the rest was 10% or less.

However, the extracts of the plant extracts that are intended to be used in the deodorant composition of the present invention, the extracts of sprinkled leaves, raspberry leaves, blackberry leaves, eucalyptus leaves, bark bark, guava leaf, hamamelis bark, and red ginseng root are all allylmethyl monosulfide. Deodorization activity of more than 35% was shown. In particular, it can be seen that the cucurbita leaf extract showed a very strong activity. In addition, it was first discovered that the extracts obtained from the rosemary, eucalyptus, locust tree, guava, hamamelis and red ginseng have allylmethyl monosulfide deodorizing activity.

Powders, tablets, chewing gum, candy, tablets, beverages, toothpastes, and deodorant sprays were prepared using the extracts of the plants prepared according to Examples 1 to 10, and their composition ratios are as follows.

Example 11 powder preparation

Lactose ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 75.0% by weight

Potato starch ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 20.0

Cucumber Leaf Extract ‥‥‥‥‥‥‥‥‥‥‥‥‥‥

Total ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 100.0

Example 12 Purification Prescription

D-mannitol ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 40.0% by weight

Lactose ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 40.0

Crystalline Cellulose ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 10.0

Hydroxypropyl Cellulose ‥‥‥‥‥‥‥‥‥‥ 5.0

Guava Leaf 50% Ethanol Extract ‥‥‥‥‥‥‥‥‥ 5.0

Total ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 100.0

Example 13: Chewing Gum Prescription

Gum base ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 20.0% by weight

Sugar ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 55.0

Glucose ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 15.0

Starch ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 9.0

Spices ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.5

Extract of Bark Tree Bark ‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.5

Total ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 100.0

Example 14 Candy Prescription

Sugar ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 50.0% by weight

Starch ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 34.0

Spices ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.5

Eucalyptus leaf extract ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.5

‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 15.0

Total ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 100.0

Example 15: Prescription of Confection

Sugar ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 76.4% by weight

Glucose ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 19.0

Sucrose fatty acid ester ‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.2

Spices ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.2

Honggyeongcheon Root 50% Ethanol Extract ‥‥‥‥‥‥‥‥‥ 0.1

‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 4.1

Total ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 100.0

Example 16: Toothpaste Prescription

Calcium Carbonate ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 50.0% by weight

Glycerin ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 20.0

Carboxymethyl Cellulose ‥‥‥‥‥‥‥‥‥‥‥‥‥ 2.0

Sodium laureth sulfate ‥‥ 2.0

Spices ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 1.0

Saccharin ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.1

Raspberry Leaf Water Extract ‥‥‥‥‥‥‥‥‥‥‥‥‥ 1.0

Chlohexidine ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 0.01

‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 23.89

Total ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 100.0
Chlorhexidine is a compound commonly used in the art, and N, N "-bis (4-chlorophenyl) -3,12-diimino-2,4, according to the IUPAC nomenclature. 11,13-tetraazatetradecanediimidamide (N, N "-Bis (4-chlorophenyl) -3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide).

Example 17 Deodorization Spray Prescription

Ethanol ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 49.5% by weight

Blackberry Leaf 50% Ethanol Extract ‥‥‥‥‥‥‥‥‥‥ 0.5

‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 50.0

Total ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 100.0

It was filled in an aerosol container with the injection gas (nitrogen gas), and the deodorant spray was prepared.

As described above, all of the plant extracts used in the present invention are conventionally used as food materials, herbal teas, and natural additives, and there is no problem in safety.

In addition, the deodorant prepared by adding the plant extract as described above can deodorize allylmethyl monosulfide, which was difficult to deodorize in the prior art, it is contained in the food and deodorant composition orally ingested or sprayed when exhaled It is possible to deodorize allyl methyl monosulfide, which is a metabolic odor of garlic.

Claims (3)

Rubus plant, Eucalyptus globulus and Psidium guajava, Myrica rubra, Everam Hamamelis virginiana, and Sedumaceae (Pheasant) Deodorant for allylmethyl monosulfide, characterized in that the one or two or more extracts selected from Rhodiola sacra (Rhodiola sacra) of the amaranth as an active ingredient. A food comprising the deodorant for allylmethyl monosulfide of claim 1. A deodorant composition comprising the deodorant for allylmethyl monosulfide of claim 1.