KR100523798B1 - Mixed granular agent for an agriculture - Google Patents

Abstract

TECHNICAL FIELD The present invention relates to a mixed granule containing a first pesticide active ingredient and a second pesticide active ingredient, wherein the second pesticide is immediately after application while preventing rapid elution of the first pesticide active ingredient. It is an object of the present invention to obtain a mixed granule for agrochemicals capable of expressing the effect of an agrochemical active ingredient.

The present invention has a structure in which the surface of the inner core particles is coated with a resin, and the outer layer portion is formed around the first core pesticide active ingredient mainly contained in the inner core particles, and the second pesticide active ingredient mainly contained in the outer layer part. It is characterized by that.

Description

Mixed granular agent for an agriculture}

The present invention relates to an agricultural mixed granule containing at least two or more pesticide active ingredients that can be stably used even when mixed. More specifically, the timing of effect expression of each pesticide active ingredient can be controlled. The present invention relates to agriculturally mixed granules, which are less likely to cause weakening.

In recent years, various mixing agents have been proposed for the purpose of energy saving of agricultural work. As such a mixing agent, the insecticide fungicide which mix | blended the compound which has bactericidal activity, and the compound which has pesticidal activity in the same agent is known, for example.

Among them, a mixing agent using Probenazole as a compound having bactericidal activity and Benfuracarb as a compound having insecticidal activity has no adverse effect such as promoting degradation among the compounds, It has a very large effect on the control of various pests and is widely used. However, when the content of probenazole is not high enough, the effect persistence may not be sufficient in some regions. For this reason, the admixture with high sustainability of the provenazole sterilization effect is calculated | required, and it was considered to increase the content of probenazole. However, increasing the content of probenazole could increase the initial elution of probenazole and cause weakening.

By the way, these mixing agents are generally used in granular form from the viewpoint of energy saving and safety at the time of dispersion. A general form of granules is an extruded granule which is prepared by mixing an active pesticide active ingredient with a carrier such as clay, mixing with water, extruding, granulating, and then drying. Increasing the content of probenazole in such a granulated form increased the initial elution concentration as described above, so that the sustainability of the bactericidal effect could not be sufficiently increased. In addition, granules coated with an agrochemical active ingredient with an adhesive on a surface of a particulate carrier having no oil absorption are known as other granules. For example, Japanese Patent Application Laid-open No. Hei 7-149606 uses a water-insoluble thermoplastic resin suspended in water as an adhesive to adhere a pesticide active ingredient to a non-oil-absorbing particulate carrier. Granulation is disclosed. Even in the case where a mixed granule was prepared by increasing the content of probenazole in such a manner, the initial elution concentration of probenazole was similarly high, and the desired sustainability of the bactericidal effect could not be obtained.

As a method of sustaining the effect of pesticide preparation for a long time, a method of imparting sustained release to pesticide preparations is known. As a method of imparting sustained release to a pesticide preparation, for example, when mixing a pesticide active ingredient and a carrier, a dissolution rate by formulating a component that prevents the dissolution of the pesticide active ingredient such as various polymers, waxes, amorphous silica, etc. The method of controlling the method, the method of impregnating a pesticide active ingredient in the carrier which has sustained release property, the method of forming a resin film on the granule surface, and controlling the elution rate are known.

However, when these methods are applied to the benfuracarb / provenazole mixture, it causes a problem that the insecticidal effect of benfuracarb is not rapidly expressed in the formulations that give sufficient sustained release to provenazole, On the other hand, in the formulation in which the effect of benfuracarb is rapidly expressed, the sustained release to provenazole is insufficient, causing a problem that the risk of weakening cannot be eliminated.

Moreover, such a problem was also a problem which arises in the combination of another pesticide active ingredient.

An object of the present invention is a mixed granule containing the first pesticide active ingredient and the second pesticide active ingredient, which can express the effect of the second pesticide active ingredient immediately after application while preventing the rapid dissolution of the first pesticide active ingredient. It is to provide an agricultural mixed granules.

The agricultural mixed granules of the present invention are agricultural mixed granules containing a first pesticide active ingredient and a second pesticide active ingredient that can be stably used even when mixed. The surface of the inner core particles is coated with an emulsion resin, and the outer layer is surrounded by an outer layer. It has a structure of forming a part, the first pesticide active ingredient is mainly contained in the inner core particles, the second pesticide active ingredient is mainly contained in the outer layer portion, the first pesticide active ingredient is Probenazole, 2 Pesticide active ingredients are Benfuracarb, Fipronil, Ethofenprox, Furathiocarb, Carbosulfan and Imidacloprid. At least one species selected from the group consisting of:

The mixed granules for agricultural use of the present invention are a pesticide active ingredient requiring a high sustained-release effect as a first pesticide active ingredient, and a pesticide active ingredient requiring rapid expression as a second pesticide active ingredient. It is preferably applicable in the combination of. Moreover, the combination of the pesticide active ingredient used for the agricultural mixed granulation of this invention is applied suitably with respect to the combination of the pesticide active ingredient which can be used stably even if it mixes. That is, the compound is preferably applied to a combination of pesticide active ingredients in a relationship that does not have adverse effects such as promoting degradation among the compounds of the pesticide active ingredient, and is not a so-called contraindication.

Examples of the pesticide active ingredient used in the agricultural mixed granules of the present invention include insecticidal active ingredients, bactericidal active ingredients, herbicide active ingredients, plant growth active ingredients and the like.

As insecticidal active ingredients, Acephate, Isoxathion, Imidacloprid, Ethylthiodemeton, Ethofenprox, Cartap, Carbosulphan (Carbosulfan), Crofentezine (Clofentezine), Chlorpyrifas-methyl, Fenbutatin-oxide, Cycloloprothrin, Dimetylrinphos, Dimethoate ), Silafluofen, Diazinon, Thiodicarb, Thiocyclam, Tebufenozide, Nitenpyram, Vamidothion, Bifenthrin, Pyridaphenthion, Pyridaben, Pyrimiphos-methyl, Fipronil, Phenisobromolate, Bupropezin (Buprofezin), Furathiocarb, Propafos, Bensultop ultap, Benfuracarb, Formothion, Marathon, Monocrotophos, BPMC, CVMC, DEP, EPN, MEP, MIPC, MPP, MTMC, NAC, PAP, PHC, PMP , XMC, and the like.

As bactericidal active ingredients, Acibenzolar-S-methyl, Azoxystrobin, Isoprothiolane, Isoprorodion, Iminoctadine triacetate, Oxolinic acid acid), Oxyquinolin copper (Oxone-copper), Kasugamycin, Carpropamid, Captan, (RS) -2-cyano-N-((R) -1- (2,4-dichlorophenyl) ethyl) -3,3-dimethylbutylamide (Development Product No. S-2900), Diclomezine, Thiabendazole, Thifluzamide , Tecloftalam, Tricyclazole, Varidamycin, Hydroxyisoxazole, Pyroquilon, Penarimol, Ferrimzone, Ferrimzone, Fthalide, Blasticidin, Furammetpyr, Flutlanil, Provenazole, Pencycuron, Polyox (Polyoxin), Metasulfocarb, Metalaxyl, Metalaxyl, Metalaxyl-M, Metominostrobin, Mepronil, CNA, IBP, DF-351, NNF-9425, NNF-9850, (RS) -2- (4-fluorophenyl) -1- (1H-1,2,4-triazol-1-yl (il))-3-trimethylsilylpropan-2-ol ( SF9701) and the like.

Herbicidal active ingredients and plant growth regulators include Azimsulfuron, Atrazine, Ametryn, Inabenfide, Imazosulfuron, Uniconazole, S. Esprocarb, Etobenzanid, Oxadiazon, Carfenstrole, Quizarofop-ethyl, Quinclorac, Cumylron , Chlomethoxynil, Cyclosulfamuron, Dithiopyr, Cinosulfuron, Cyhalofop-butyl, Simazine, Dimethamethine ( Dimetametryn, Dimepiperate, Cinmethylin, Dymron, Thenylchor, Triaphentenol, Naproanilide, Paclobutrazol ), Bifenox, Piperophos, Pyrazoxyfen, Pyrazulfuronethyl (Py) razosulfuron-ethyl, Pyrazolate, Pyributicarb, Pyriminobac-methyl, Butachlor, Butamifos, Pretilachlor, Bromobutide, Bensulfuron-methyl, Benzofenap, Bentazon, Benthiocarb, Pentoxazone, Benfuresate, Menfuresate Mefenacet, molinate, ACN, CNP, 2,4-D, MCPB, MCPB ethyl and the like, and plant growth regulators.

Generally, some of the pesticide active ingredients are eluted in large quantities at one time, causing problems such as damage to crops, affecting aquatic organisms such as fish, or strong odor. Usually, the problems can be avoided by controlling the elution amount of the pesticide active ingredient. Moreover, it can also be expected to provide the persistence of the effect by controlling the amount of elution. In one embodiment of the preferred admixture according to the present invention, among the different active ingredients, the active ingredient which further needs to be controlled for elution according to a certain purpose is used as the first pesticide active ingredient, and the other active ingredient is used as the second pesticide active ingredient. It is preferable to apply. As such a combination of pesticide active ingredients, specifically, benvencarcarb, fipronil, etofenprox, furathiocarb, and carbosulfane as the first pesticide active ingredient and provenazole as the second pesticide active ingredient And combinations of at least one species selected from imidacroprids. In particular, examples thereof include granules using provenazole as the first pesticide active ingredient and benfuracarb as the second pesticide active ingredient.

Probenazole, which is preferably used as the first pesticide active ingredient, is a generic name 3-aryloxy-1,2-benzoisothiazole-1,1-dioxide, and is a compound having an excellent effect in controlling the blasting disease. As for the compounding quantity of the provenazole in the granule of this invention, 3 to 70 weight% is preferable with respect to the whole granule, More preferably, it is 8 to 70 weight%, More preferably, it is 8 to 50 weight%.

Benfuracarb which is preferably used as the second pesticide active ingredient, has the chemical name ethyl = N- [2,3-dihydro-2,2-dimethylbenzofuran-7-iroxycarbonyl (methyl) aminothio]- N-isopropyl-β-alaninate, Lisorhoptrus oryzophilus, Laodelphax striatellus, Sogatella furcifera, Nephotettix cincticeps, Olema oryzae It is highly effective in controlling pests such as Aphelenchoides besseyi. In the granulation of the present invention, the blending amount of benfuracarb is preferably 1 to 30% by weight, more preferably 1 to 20% by weight based on the entire granulation.

In the present invention, in the case of using other pesticide active ingredients as the first pesticide active ingredient and the second pesticide active ingredient, the compounding amount can be appropriately adjusted in consideration of the medicinal effects of the pesticide active ingredient based on the above compounding amount.

The inner core particles of the granules according to the present invention are composed of the first pesticide active ingredient, a solid carrier and other ingredients to be blended as necessary.

Examples of the solid carrier include bentonite, clay, kaolin, sericite, talc, acidic clay, pumice, zeolite and vermiculite. , Pearlite, calcium carbonate, silica sand and the like can be exemplified.

Moreover, as other components, such as sustained release improvers, such as a wax, alkyl sulfate ester salts, aryl sulfonate, polyoxyethylene glycol ethers, polyhydric alcohol esters, dialkyl sulfosuccinates, polycarboxylic acids, etc. Surfactant, starch, alginic acid, glycerin, polyvinylpyrrolidone, polyurethane, polyethylene glycol, polypropylene glycol, polybutene, polyvinyl alcohol, gum arabic, liquid paraffin, ethyl cellulose, polyvinylacetate Coloring agents, such as a binder, dye, and a pigment, etc. can be illustrated.

The granular inner core particles of the present invention are formed with a resin film. As resin, an emulsion resin is preferable, and as said emulsion resin, the emulsion of a polyurethane resin, a vinyl acetate resin, a styrene resin, an acrylic resin, a copolymer thereof, and these mixture can be illustrated. Although there is no restriction | limiting in particular in solid content of emulsion at the time of manufacture, 1-55 weight% is preferable, More preferably, it is 15-45 weight%.

As a commercial item of a polyurethane resin, for example, a brand name "Nipporan 2606" (Nippon Polyurethane High School Co., Ltd.), a brand name "Bondick 2220", "Hylan AP-20", "Hylan AP-40 (F)" (Dai Nippon Ingiga Chemical Co., Ltd.), a brand name `` Parmaline UA-150 '' (Sanyo Sego Co., Ltd.), a brand name `` Olesta UD100N '' (Mitsuigagaku Kabuki Kaisha), a brand name `` Superplex 160 "," Superplex 750 "," Superplex 410 "," Superplex 126 "(Daiichigogyo Seiyaku Co., Ltd.), etc. are mentioned.

These resins include butyl cellosolve, carbitol, butyl carbitol, methyl cellosolve, butyl cellosolve acetate, carbitolol acetate, butyl carbitol acetate, and methyl cellosolve as a film forming aid. Acetate etc. can be mix | blended and used. As a compounding quantity, 0 to 15% normally, about 50% can be illustrated with respect to solid content normally.

The granular outer layer part of this invention is comprised from a 2nd pesticide active ingredient and the other component mix | blended as needed.

Other components include agrochemical active ingredient stabilizers such as alkali metal salts, alkaline earth metal salts and epoxidized oils and fats, solid carriers such as bentonite, diatomaceous earth and white carbon, and solid carriers exemplified as inner core particle components, sustained release enhancers, surfactants, and binders. And other pesticide active ingredients.

In the granulation of the present invention, a sustained release agent such as paraffin wax is blended into the outer layer portion, or a film made of an emulsion resin or the like is formed on the outer layer portion so that the first pesticide active ingredient and the second pesticide active ingredient are both released slowly. It is also possible to set the granule to which the property is imparted, in which the sustained release effect of the first pesticide active ingredient is set relatively higher than the sustained release effect of the second pesticide active ingredient.

In the preparation of the granules of the present invention, 1) a conventional agrochemical granulator such as an extrusion granulator, a stirring granulator, a rolling granulator or a fluidized bed granulator is used as the first pesticide active ingredient, a solid carrier and, if necessary, other components. 2) The first pesticide active ingredient is prepared by using a conventional mixer, such as a concrete mixer or a Nauta mixer, to the central particles obtained by the same method as in 1) without containing the first pesticide active ingredient. Impregnation or 3) a method of adhering the first pesticide active ingredient to the surface of a non-oil-absorbing carrier such as silica sand and calcium carbonate with a solid carrier or other components, if necessary, using an appropriate binder, or the like. Prepare the particles. As the shape of the inner core particles, a spherical material having a diameter of 0.1 to 30 mm, a diameter of 0.1 to 5 mm, a length of 1 to 30 mm, and a cylindrical shape having an aspect ratio (length / diameter) of 1 to 10 can be exemplified. .

Subsequently, resin, such as an emulsion resin, is coat | covered and dried on the inner core particle surface by means of spraying or dripping, or the component of an outer layer part can be added one by one or simultaneously simultaneously in an undried state. At this time, it can be added at normal temperature or under heating, and after addition, it can be dried using means, such as heating, pressure reduction, and blowing. However, the adhesiveness of an outer layer part can also be improved by adding the structural component of an outer layer part in the state which provided adhesiveness or adhesiveness to a film by means, such as not drying or making it partially dry. It is preferable to perform these processes, mixing or driving inner core particle | grains using normal mixers, such as a concrete mixer, a Knoter mixer, and a ribbon mixer.

Example of Applied Crops: Rice Planted in Paddy Fields

How to use: seedling box

Usage amount per 10 ar (a): 0.1-10 kg, usually about 1 kg

When to use: Before planting

(Example)

Hereinafter, the present invention will be described in more detail with reference to Examples, Comparative Examples and Test Examples. In addition, hereinafter, only "parts" means "parts by weight", and "%" indicates "% by weight".

Example 1

12 parts of probenazole technical substance (active ingredient amount), bentonite (brand name "C bento", neo-light high altitude Kabushi Kaisha), 3 parts of alpha starch (brand name "Matsunorin M", Matsutani Kagaku Kashiki) Kaisha) 2 parts were added, clay (brand name "NO clay", neo-light algae Co., Ltd.) was added to 80 parts of the above ingredients, mixed, and 24 parts of water were added and mixed, followed by extrusion granulator (basket riser, Fuji). The powder was extruded into a cylindrical shape having a diameter of 1.2 mm, powdered, and sized to an aspect ratio of about 3. Then, dried at 60 ° C. for 2 hours to obtain an inner core particle (A).

While spraying the obtained inner core particles (A) with a concrete mixer, spray 4 parts of polyurethane water dispersion (brand name "Superflex 130", Daiichi-kyokyo Seiyaku Co., Ltd., 35% solids content) to the surface of the inner core particles (A). By forming a polyurethane film on the surface by adding 0.3 part of white carbon, it dried at 60 degreeC for 2 hours. While stirring the obtained polyurethane-coated inner core particles, 2.5 parts (the amount of active ingredient) of benfuracarb element and 1.5 parts of white carbon (brand name "Toxyyl AL-1", Tokuyama Co., Ltd.) were added several times alternately, and it continued. Thus, the clay (NO clay) was added so that the whole was 100 parts in solid content, and the insecticidal sterilization mixed granule of Example 1 was obtained.

Example 2

24 parts of Probenazole original substance (active ingredient amount), 3 parts of bentonite (C vent), 2 parts of polyvinyl alcohol (trade name "PVA 224", Clare Kabushi Kaisha) were added, and the clay (NO clay) was added to the above ingredients. After addition, the mixture was further mixed, 23.3 parts of water was added and mixed, and cylindrical basket particles having a diameter of 1 mm and an aspect ratio of about 3 were obtained with a basket flowr, and dried at 60 ° C. for 2 hours to obtain an inner core particle (B). .

7 parts of ionomer type aqueous urethane resin (brand name "Hylan AP-20", Dainippon Ingiga Chemical Co., Ltd., 30% of solid content), while rolling the obtained inner core particle (B) with a concrete mixer. By spraying on the surface, a polyurethane film was formed on the surface, and 1.5 parts of calcium carbonate was further added. After drying at 60 ° C. for 2 hours, 5 parts of Benfuracarb element (active ingredient amount) and white carbon (trade name "Caprex # 1120", Shionogi Seiyaku Co., Ltd.) 3.5 while stirring the obtained polyurethane-coated inner core particles 3.5 The parts were divided in turn and added alternately, and the clay (NO clay) was added so that the whole was 100 parts in solid content, and the insecticidal sterilization mixed granule of Example 2 was obtained.

Example 3

8 parts of polyurethane aqueous dispersions (brand name "Superflex 126", Daiichi-kyokyo Seiyaku Co., Ltd., 30% of solid content) while carrying out the inner core particle (B) obtained by carrying out similarly to Example 2 with a concrete mixer By spraying on the surface of, a polyurethane film was formed on the surface, and it dried at 60 degreeC after that for 2 hours. While stirring the obtained polyurethane-film inner core particles, 5 parts (the active ingredient amount) of benfuracarb and 3 parts of white carbon (brand name "Caprex CS-7" and Shionogi Seiyaku Co., Ltd.) are added several times alternately, Then, the clay (NO clay) was added so that the whole may be 100 parts with solid content, and the insecticidal sterilization mixed granulation of Example 3 was obtained.

Example 4

24 parts of Probenazole original (active ingredient), 2.5 parts of Benfuracarb original (active ingredient amount), 3 parts of bentonite (C bento), and 2 parts of polyvinyl alcohol (PVA 224) were added, and the clay (NO clay) The mixture was added to 78.4 parts, mixed, and mixed with 13.3 parts of water and 10 parts of special paraffin wax (trade name "Purnet 101Z", manufactured by Shin-Nakamura Chemical Co., Ltd., 50% solids content), followed by a basket riser. Cylindrical inner core particles were obtained using (screen 1.0 mm), which were sized using a marmerizer to obtain almost spherical inner core particles (C) having an aspect ratio (long diameter / short diameter) of about 1.5. .

4.5 parts of vinyl acetate-based resin emulsions (brand name "Polyzool S-400", Showa Kobunshi Co., Ltd., 53% of solid content) are spray-treated on the surface of an inner core particle, rolling the obtained inner core particle (C) with a concrete mixer. Thereby, a polyurethane film is formed on the surface, 2.5 parts (active ingredient amount) of clay (NO clay) and benfuracarb element are gradually added while continuing stirring, and dried at 60 degreeC for 2 hours, and the insecticide of Example 4 is carried out. 100 parts of sterile mixed granules were obtained.

Example 5

In Example 3, in place of 8 parts of polyurethane aqueous dispersion (Superflex 126), lacquer-type polyurethane resin (trade name "Baan Nok 16-411", Dainippon Ingiga Chemical Co., Ltd., solid content 50%) 5 Except for using a part, it carried out similarly to all, and the insecticidal sterilization mixed granulation of Example 5 was obtained.

Example 6

24 parts of Probenazole original (active ingredient amount), 3 parts of bentonite (C bento), 2 parts of polyvinyl alcohol (trade name "PVA 224", Clare Kabushi Kaisha) were added, and the clay (NO clay) was added to the above ingredients, and 74.7 After addition, the mixture was further mixed, 23 parts of water was added and mixed, and cylindrical basket particles having a diameter of 1 mm and an aspect ratio of about 3 were obtained with a basket flowr, and dried at 60 ° C. for 2 hours to obtain internal core particles (D).

6.5 parts of the ionomer-type aqueous urethane resin (brand name "Hyran AP-40 (F)", Dainippon Ingiga Chemical Co., Ltd., 22.5% of solid content) while rolling the obtained inner core particle (D) with a concrete mixer By spraying on the particle surface, the polyurethane film was formed in the surface, and it dried at 60 degreeC after that for 2 hours. While stirring the obtained polyurethane-coated inner core particles, 5 parts of benfuracarb element (active ingredient amount), 7 parts of white carbon (caprex # 1120), paraffin wax (brand name "Toyo Parax A40S", Toso Kabushiki Kaisha, chloride 5 parts of paraffin and 40% of chlorine content were added sequentially, and the clay (NO clay) was added so that the whole may be 100 parts with solid content, and the insecticidal sterilization mixed granulation of Example 6 was obtained.

Example 7

24 parts of Provenazole original (active ingredient), 2.5 parts of Benfuracarb original (active ingredient amount), 1.5 parts of bentonite (C vent), and 1.5 parts of polyvinyl alcohol (PVA 224) were added, and clay (NO clay) was added to the above components. Add to 88 parts of water, and further mix, add 18.8 parts of water and 6 parts of special paraffin wax (Purnet 101Z), mix, and then use a basket reducer (screen 1.0 mm) to make a diameter of 1 mm and an aspect ratio of about 3 Cylindrical inner core particles of were obtained and dried at 60 ° C. for 1 hour to obtain inner core particles (E).

While spraying the obtained inner core particle (E) with a concrete mixer, 2.6 parts of water-based polyurethane resins (brand name "Nippora 2606", Nippon Polyurethane Co., Ltd., 40% of solid content) are sprayed on the surface of an inner core particle, A urethane film was formed. While continuing stirring, 2.5 parts of benfuracarb element (active ingredient amount) and white carbon (brand name "Sipyrina art 50S", Shionogi Seiyaku Kabuki Kaisha) are added in turn and added in turn, and then the aqueous polyurethane resin ( Nipporan 2606) 2.6 parts were sprayed. This was dried at 60 degreeC for 1 hour, and the insecticidal sterilization mixed granulation of Example 7 was obtained.

Comparative Example 1

12 parts of probenazole element (active ingredient amount), 2.5 parts of benfuracarb element (active ingredient amount), 3 parts of bentonite (C bento), 2 parts of alpha starch (matsunorin M), white carbon (methoxyyl AL-1) ) 1.8 parts and clay (NO clay) were added and mixed, 24 parts of water was added and mixed, and a cylindrical inner core particle having a diameter of 1.2 mm and an aspect ratio of about 3 was obtained with a basket holder. After drying at 60 ° C. for 2 hours, 4 parts of a polyurethane water dispersion (Superflex 130) was sprayed while rolling with a concrete mixer to form a polyurethane film on the surface, and dried at 60 ° C. for 2 hours, followed by mixing of Comparative Example 1 100 parts of granules were obtained.

Comparative Example 2

Probenazole original 24 parts (active ingredient amount), benfuracarb 5 parts (active ingredient amount), white carbon (Caprex # 1120) 3.5 parts, bentonite (C bento) 3 parts, polyvinyl alcohol (PVA 224) 2 parts 1.5 parts of calcium carbonate was added, and then 100 parts of clay (NO clay) was added and mixed, 23.3 parts of water was added and mixed, and then a cylindrical inner core particle having a diameter of 1 mm and an aspect ratio of about 3 was obtained with a basket holder. This was dried at 60 degreeC for 2 hours, and 100 parts of mixed granules of the comparative example 2 were obtained.

Comparative Example 3

24 parts of Probenazole original (active ingredient), 2.5 parts of Benfuracarb original (active ingredient), 3 parts of bentonite (C bento), 2 parts of polyvinyl alcohol (PVA 224) were added, and clay (NO clay) was further added. 13.3 parts of water and 10 parts of special paraffin wax (Prunit 101Z) were added and mixed. Cylindrical inner core particles were obtained by using a basket reducer (screen 1.0 mm), and a marfurizer was formed into an almost spherical shape having an aspect ratio of about 1.5. Part (active ingredient amount) was added slowly. This was dried at 60 degreeC for 2 hours, and 100 parts of mixed granules of the comparative example 3 were obtained.

Comparative Example 4

After adding 24 parts of Probenazole original substance (active ingredient amount), 2 parts of polyvinyl alcohol (PVA224), 3 parts of magnesium stearate, and clay (NO clay), and adding and mixing 23.3 parts of water, Screen 1.0 mm) to obtain cylindrical inner core particles having a diameter of 1 mm and an aspect ratio of about 3. After drying at 60 ° C. for 2 hours, 5 parts (active ingredient amount) of benfuracarb was gradually added while rolling with a concrete mixer, and 100 parts of mixed granules of Comparative Example 4 were obtained.

Comparative Example 5

2.5 parts (effective amount) of benfuracarb element was slowly added to white carbon (methoxyyl AL-1), and after mixing enough, 12 parts (probe amount) of probenazole element were added and mixed, and mixture A was obtained. . Next, while mixing 82 parts of silica sand, 4 parts of polyurethane water dispersion (Superflex 130) was diluted in an appropriate amount of water, and the mixture A was mixed and uniformly coated, followed by drying at 60 ° C. for 2 hours, and Comparative Example 5 100 parts of mixed granules were obtained.

The compounding compositions of Examples 1 to 7 and Comparative Examples 1 to 5 obtained as described above are collectively shown in Tables 1 to 3.

Example 1 Example 2 Example 3 Inner nuclear particles Probenazole 12 parts Bentonite 3 parts α-ized starch 2 parts Clay 63 parts Probenazole 24 parts Bentonite 3 parts PVA 2 parts Clay 52.2 parts Probenazole 24 parts Bentonite 3 parts PVA 2 parts Clay 52.2 parts Coating resin 4 parts of polyurethane water dispersion (1.4 parts) Ionomer-type aqueous urethane 7 parts (2.1 parts) 8 parts polyurethane dispersion (2.4 parts) Outer layer Ventura Carb 2.5 parts White Carbon 1.8 parts Clay Rest Calcium Carbonate 1.5 parts Benfuracarb 5 parts White Carbon 3.5 parts Clay Rest Ventura Carb Part 5 White Carbon Part 3 Clay Rest Sum                      100 copies                      100 copies                    100 copies

Example 4 Example 5 Example 6 Example 7 Inner core particles Probenazole 24 parts Benfurakarpe 2.5 parts Bentonite 3 parts PVA 2 parts Clay 46.9 parts Wax 10 parts (5 parts) Probenazole 24 parts Bentonite 3 parts PVA 2 parts Clay 52.2 parts Probenazole 24 parts Bentonite 3 parts PVA 2 parts Clay 45.7 parts Probenazole 24 parts Benfuracarb 2.5 parts Bentonite 1.5 parts PVA 1.5 parts Clay 58.5 parts Wax 6 parts (3 parts) Coating resin 4.5 parts (2.4 parts) of vinyl acetate emulsion Lacca-type Polyurethane Dispersion (5 parts) Ionomer-type aqueous urethane 6.5 parts (1.46 parts) Water-based polyurethane resin 2.6 parts (1.04 parts) Outer layer Clay Restbenfuracarb 2.5 Ventura Carb Part 5 White Carbon Part 3 Clay Rest Ventura Carb Part 5 White Carbon Part 7 Wax 5 Part Clay Rest Benpurakar 2.5 parts white carbon rest Coating resin Water-based polyurethane resin 2.6 parts (1.04 parts) Sum            100 copies           100 copies           100 copies             100 copies

Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Inner core particles Probenazole 12 parts Benfururacarb 2.5 parts Bentonite 3 parts α-ized starch 2 parts White carbon 1.8 parts Clay Rest Probenazole 24 parts Benfuracarb 5 parts White carbon 3.5 parts Bentonite 3 parts PVA 2 parts Calcium carbonate 1.5 parts Clay 61 parts Probenazole 24 parts Benfuracarb 2.5 parts Bentonite 3 parts PVA 2 parts Clay Rest wax 10 parts (5 parts) Probenazole 24 parts PVA 2 magnesium stearate 3 parts clay Rest Silica 82 Coating resin 4 parts of polyurethane water dispersion (1.4 parts) none none none 4 parts of polyurethane water dispersion (1.4 parts) Outer layer none none Benfuracarb Part 2.5 Benfuracarb Part 5 White Carbon Rest Benfuracarb 2.5 parts Provenazole 12 parts Sum          100 copies          100 copies          100 copies          100 copies        100 copies

Test Example 1 (Dissolution Test)

160 mg of each mixed granule of Examples 1 to 4 and Comparative Examples 1 to 5 was charged into a beaker containing 800 ml of activated carbon treated water. Every predetermined time, the test liquid was extract | collected from the center part of the beaker, the content of the active ingredient was measured by high performance liquid chromatography, and the dissolution rate was computed. The results are shown in Table 4.

Disclosure Ingredient Name Dissolution Rate (%) 2 days later 4 days later 6 days later 8 days later 10 days later Example 1 Probenazole  6.7 13.0 19.2 25.0 30.7 Benpuracarb  7.2 14.4 21.6 27.6 33.6 Example 2 Probenazole  6.7 12.7 18.1 23.3 28.1 Benpuracarb  8.0 15.0 21.0 26.0 31.0 Example 3 Probenazole  7.7 15.0 22.3 29.4 36.0 Benpuracarb  8.0 15.0 22.0 27.0 32.0 Example 4 Probenazole  9.0 17.1 24.2 30.4 35.8 Benpuracarb  7.0 13.0 19.0 25.0 30.0 Comparative Example 1 Probenazole  8.5 17.7 26.7 35.1 42.2 Benpuracarb  4.6  9.9 14.8 18.6 20.3 Comparative Example 2 Probenazole 14.4 26.7 37.1 47.3 57.1 Benpuracarb  8.2 16.5 24.3 31.6 38.0 Comparative Example 3 Probenazole 14.2 25.6 35.2 42.7 49.0 Benpuracarb  9.4 17.9 24.7 30.6 35.7 Comparative Example 4 Probenazole 12.4 23.3 32.7 40.6 47.6 Benpuracarb  8.5 16.9 24.2 30.0 33.4 Comparative Example 5 Probenazole 17.9 29.2 39.5 49.7 59.8 Benpuracarb 12.8 20.2 29.6 37.5 43.2

As can be seen from the results in Table 4, it can be seen that in the mixed granules of Examples 1 to 4 according to the present invention, benfuracarb rapidly elutes and provenazole elutes with sustained release.

In the above embodiment, the description has been made with the example of provenazole as the first pesticide active ingredient and benfuracarb as the second pesticide active ingredient, but the present invention is not limited to these combinations. It is also applicable to.

According to the present invention, in an agricultural mixed granule containing a first pesticide active ingredient and a second pesticide active ingredient which can be used stably even after mixing, the second pesticide is immediately released from the first application while preventing rapid elution of the first pesticide active ingredient. An agricultural mixed granule capable of expressing the effect of the pesticide active ingredient can be provided.

Claims (6)

As an agricultural mixed granule containing the 1st pesticide active ingredient and the 2nd pesticide active ingredient which can be used stably even if mixed, It has a structure which coat | covers the surface of an inner core particle with an emulsion resin, and formed the outer layer part around it, the 1st pesticide active ingredient is mainly contained in an inner core particle, the 2nd pesticide active ingredient is mainly contained in an outer layer part, The first pesticide active ingredient is Probenazole, the second pesticide active ingredient is Benfuracarb, Fipronil, Ethofenprox, Furathiocarb, Agricultural granules, characterized in that at least one species selected from the group consisting of Carbosulfan and imidacloprid. delete delete The agricultural granulated granules according to claim 1, wherein the content of probenazole is 3 to 70% by weight based on the whole granules. The agricultural granulated granules according to claim 1, wherein the content of probenazole is 8 to 70% by weight based on the whole granules. The agricultural mixed granulation according to any one of claims 1, 4 and 5, wherein the emulsion resin covering the inner core particles is a polyurethane resin.