KR100468977B1 - 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산 - Google Patents

분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산

Info

Publication number
KR100468977B1
KR100468977B1 KR10-2004-7013508A KR20047013508A KR100468977B1 KR 100468977 B1 KR100468977 B1 KR 100468977B1 KR 20047013508 A KR20047013508 A KR 20047013508A KR 100468977 B1 KR100468977 B1 KR 100468977B1
Authority
KR
South Korea
Prior art keywords
polypeptides
present
secretory
nucleic acids
acids encoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR10-2004-7013508A
Other languages
English (en)
Korean (ko)
Other versions
KR20040096629A (ko
Inventor
데이비드 보츠타인
루크 데스노이어스
나폴레옹 페라라
셔만 퐁
웨이-퀴앙 가오
오드리 고다드
오스틴 엘. 거니
제임스 판
마가렛 안 로이
티모시 에이. 스튜워트
다니엘 투마스
콜린 케이. 와따나베
윌리엄 아이. 우드
Original Assignee
제넨테크, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/en
Application filed by 제넨테크, 인크. filed Critical 제넨테크, 인크.
Publication of KR20040096629A publication Critical patent/KR20040096629A/ko
Application granted granted Critical
Publication of KR100468977B1 publication Critical patent/KR100468977B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR10-2004-7013508A 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산 Expired - Fee Related KR100468977B1 (ko)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US11285198P 1998-12-16 1998-12-16
US11314598P 1998-12-16 1998-12-16
US60/112,851 1998-12-16
US60/113,145 1998-12-16
US11351198P 1998-12-22 1998-12-22
US60/113,511 1998-12-22
US11556599P 1999-01-12 1999-01-12
US11573399P 1999-01-12 1999-01-12
US11555899P 1999-01-12 1999-01-12
US60/115,733 1999-01-12
US60/115,558 1999-01-12
US60/115,565 1999-01-12
US11934199P 1999-02-09 1999-02-09
US60/119,341 1999-02-09
US11953799P 1999-02-10 1999-02-10
US60/119,537 1999-02-10
US11996599P 1999-02-12 1999-02-12
US60/119,965 1999-02-12
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
USPCT/US99/12252 1999-06-02
PCT/US1999/028634 WO2000036102A2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR10-2001-7007461A Division KR100468978B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산

Publications (2)

Publication Number Publication Date
KR20040096629A KR20040096629A (ko) 2004-11-16
KR100468977B1 true KR100468977B1 (ko) 2005-02-02

Family

ID=27578476

Family Applications (2)

Application Number Title Priority Date Filing Date
KR10-2004-7013508A Expired - Fee Related KR100468977B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산
KR10-2001-7007461A Expired - Fee Related KR100468978B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR10-2001-7007461A Expired - Fee Related KR100468978B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산

Country Status (8)

Country Link
EP (1) EP1141285A2 (enrdf_load_stackoverflow)
JP (5) JP2003521229A (enrdf_load_stackoverflow)
KR (2) KR100468977B1 (enrdf_load_stackoverflow)
AU (7) AU777006B2 (enrdf_load_stackoverflow)
CA (1) CA2348757A1 (enrdf_load_stackoverflow)
IL (11) IL142794A0 (enrdf_load_stackoverflow)
MX (1) MXPA01006057A (enrdf_load_stackoverflow)
WO (1) WO2000036102A2 (enrdf_load_stackoverflow)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US6914130B2 (en) * 1998-06-17 2005-07-05 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
EP2292761A1 (en) 1999-03-11 2011-03-09 Merck Serono S.A. Vascular adhesion molecules and modulation of their function
AU2008201101B2 (en) * 1999-03-11 2011-01-20 Merck Serono Sa Vascular adhesion molecules and modulation of their function
KR100543857B1 (ko) * 1999-09-01 2006-01-23 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제
DE19947010A1 (de) * 1999-09-30 2001-04-05 Universitaetsklinikum Freiburg Das Gen PRV-1 und dessen Verwendung
WO2001083719A2 (en) * 2000-04-28 2001-11-08 Millennium Pharmaceuticals, Inc. 25692, a novel human o-methyltransferase family member and uses thereof
GB0110273D0 (en) * 2001-04-26 2001-06-20 Inpharmatica Ltd Novel proteins
WO2003053334A2 (en) * 2001-12-19 2003-07-03 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
EP1514942A4 (en) * 2002-05-17 2007-05-16 Kyowa Hakko Kogyo Kk METHOD FOR SEARCHING FOR A SUBSTANCE ANTIDIABETIC EFFECT
EP1546341A1 (en) * 2002-10-02 2005-06-29 DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung Mipp1 homologous nucleic acids and proteins involved in the regulation of energy homeostatis
NZ594285A (en) 2005-11-04 2013-02-22 Genentech Inc USE OF COMPLEMENT PATHWAY INHIBITOR ANTIBODY AGAINST C5a TO TREAT OCULAR DISEASES
CA2663243A1 (en) 2006-09-28 2008-04-03 Merck Serono S.A. Junctional adhesion molecule-c (jam-c) binding compounds and methods of their use
MY157948A (en) 2006-11-02 2016-08-30 Genentech Inc Humanized anti-factor d antibodies
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
RU2015117054A (ru) 2008-05-06 2015-10-20 Дженентек, Инк. ВАРИАНТЫ CRIg С СОЗРЕВШЕЙ АФФИНОСТЬЮ
BR112016002845A2 (pt) 2013-08-12 2017-09-12 Genentech Inc composições e métodos para tratar condições associadas ao complemento
TW201623337A (zh) 2014-05-01 2016-07-01 建南德克公司 抗－因子ｄ抗體變異體及其用途
US10654932B2 (en) 2015-10-30 2020-05-19 Genentech, Inc. Anti-factor D antibody variant conjugates and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001970A (en) * 1994-11-07 1999-12-14 Merck & Co., Inc Modified human neuropeptide Y1 Receptors
AU1532697A (en) * 1996-01-12 1997-08-01 Genetics Institute Inc. Beta-chemokine, h1305 (mcp-2)
AU746956B2 (en) * 1997-05-06 2002-05-09 Zymogenetics Inc. Novel tumor antigens
DE19818620A1 (de) * 1998-04-21 1999-10-28 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Blase-Normal
WO2000000610A2 (en) * 1998-06-26 2000-01-06 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
WO2000004135A2 (en) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Human scad-related molecules, scrm-1 and scrm-2
DE19849044A1 (de) * 1998-10-23 2000-04-27 Univ Ludwigs Albert Das Gen PRV-1 und dessen Verwendung
JP2002530080A (ja) * 1998-11-19 2002-09-17 インサイト・ファーマスーティカルズ・インコーポレイテッド 免疫グロブリン・スーパーファミリー・タンパク質
ES2321954T3 (es) * 1999-03-08 2009-06-15 Genentech, Inc. Composiciones y procedimientos para el diagnostico de tumores.

Also Published As

Publication number Publication date
AU2004237842B2 (en) 2007-09-20
IL188579A0 (en) 2008-04-13
AU2004237923B2 (en) 2007-09-06
AU2004237922B2 (en) 2007-09-06
AU777006B2 (en) 2004-09-30
IL142794A (en) 2008-03-20
JP2004041217A (ja) 2004-02-12
AU1932000A (en) 2000-07-03
MXPA01006057A (es) 2003-09-10
IL188580A0 (en) 2008-04-13
IL201001A0 (en) 2010-05-17
AU2004237921A1 (en) 2005-01-13
AU2004237919B2 (en) 2007-09-06
AU2004237920A1 (en) 2005-01-13
IL201030A0 (en) 2010-05-17
KR20010101224A (ko) 2001-11-14
AU2004237919A1 (en) 2005-01-13
JP2007075118A (ja) 2007-03-29
AU2004237923A1 (en) 2005-01-13
CA2348757A1 (en) 2000-06-22
KR20040096629A (ko) 2004-11-16
AU2004237921B2 (en) 2007-08-23
AU2004237920B2 (en) 2007-08-23
IL142794A0 (en) 2002-03-10
IL188576A0 (en) 2008-04-13
JP2004041218A (ja) 2004-02-12
KR100468978B1 (ko) 2005-02-02
EP1141285A2 (en) 2001-10-10
JP2007312779A (ja) 2007-12-06
WO2000036102A3 (en) 2000-11-09
WO2000036102A2 (en) 2000-06-22
JP2003521229A (ja) 2003-07-15
AU2004237842A1 (en) 2005-01-13
IL200883A0 (en) 2010-05-17
IL188581A0 (en) 2008-04-13
AU2004237922A1 (en) 2005-01-13
IL188578A0 (en) 2008-04-13
IL188577A0 (en) 2008-04-13

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