KR100468977B1 - Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same - Google Patents

Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Info

Publication number
KR100468977B1
KR100468977B1 KR10-2004-7013508A KR20047013508A KR100468977B1 KR 100468977 B1 KR100468977 B1 KR 100468977B1 KR 20047013508 A KR20047013508 A KR 20047013508A KR 100468977 B1 KR100468977 B1 KR 100468977B1
Authority
KR
South Korea
Prior art keywords
polypeptides
present invention
secreted
same
nucleic acids
Prior art date
Application number
KR10-2004-7013508A
Other languages
Korean (ko)
Other versions
KR20040096629A (en
Inventor
데이비드 보츠타인
루크 데스노이어스
나폴레옹 페라라
셔만 퐁
웨이-퀴앙 가오
오드리 고다드
오스틴 엘. 거니
제임스 판
마가렛 안 로이
티모시 에이. 스튜워트
다니엘 투마스
콜린 케이. 와따나베
윌리엄 아이. 우드
Original Assignee
제넨테크, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US11314598P priority Critical
Priority to US11285198P priority
Priority to US60/112,851 priority
Priority to US60/113,145 priority
Priority to US11351198P priority
Priority to US60/113,511 priority
Priority to US60/115,558 priority
Priority to US60/115,565 priority
Priority to US11555899P priority
Priority to US11573399P priority
Priority to US11556599P priority
Priority to US60/115,733 priority
Priority to US60/119,341 priority
Priority to US11934199P priority
Priority to US60/119,537 priority
Priority to US11953799P priority
Priority to US60/119,965 priority
Priority to US11996599P priority
Priority to PCT/US1999/012252 priority patent/WO1999063088A2/en
Priority to USPCT/US99/12252 priority
Application filed by 제넨테크, 인크. filed Critical 제넨테크, 인크.
Priority to PCT/US1999/028634 priority patent/WO2000036102A2/en
Publication of KR20040096629A publication Critical patent/KR20040096629A/en
Application granted granted Critical
Publication of KR100468977B1 publication Critical patent/KR100468977B1/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Abstract

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
KR10-2004-7013508A 1998-06-02 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same KR100468977B1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
US11314598P true 1998-12-16 1998-12-16
US11285198P true 1998-12-16 1998-12-16
US60/112,851 1998-12-16
US60/113,145 1998-12-16
US11351198P true 1998-12-22 1998-12-22
US60/113,511 1998-12-22
US11555899P true 1999-01-12 1999-01-12
US11573399P true 1999-01-12 1999-01-12
US11556599P true 1999-01-12 1999-01-12
US60/115,733 1999-01-12
US60/115,558 1999-01-12
US60/115,565 1999-01-12
US11934199P true 1999-02-09 1999-02-09
US60/119,341 1999-02-09
US11953799P true 1999-02-10 1999-02-10
US60/119,537 1999-02-10
US11996599P true 1999-02-12 1999-02-12
US60/119,965 1999-02-12
USPCT/US99/12252 1999-06-02
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
PCT/US1999/028634 WO2000036102A2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR10-2001-7007461A Division KR100468978B1 (en) 1998-06-02 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Publications (2)

Publication Number Publication Date
KR20040096629A KR20040096629A (en) 2004-11-16
KR100468977B1 true KR100468977B1 (en) 2005-02-02

Family

ID=27578476

Family Applications (2)

Application Number Title Priority Date Filing Date
KR10-2004-7013508A KR100468977B1 (en) 1998-06-02 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
KR10-2001-7007461A KR100468978B1 (en) 1998-06-02 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR10-2001-7007461A KR100468978B1 (en) 1998-06-02 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Country Status (8)

Country Link
EP (1) EP1141285A2 (en)
JP (5) JP2003521229A (en)
KR (2) KR100468977B1 (en)
AU (7) AU777006B2 (en)
CA (1) CA2348757A1 (en)
IL (11) IL142794D0 (en)
MX (1) MXPA01006057A (en)
WO (1) WO2000036102A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
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US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
MXPA04005945A (en) * 2001-12-19 2004-11-01 Genentech Inc Compositions and methods for the diagnosis and treatment of tumor.
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
KR100543857B1 (en) * 1999-09-01 2006-01-23 제넨테크, 인크. Promotion or Inhibition of Angiogenesis and Cardiovascularization
CA2405791A1 (en) * 1999-02-10 2000-06-22 Genetech,Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AT500328T (en) * 1999-03-11 2011-03-15 Merck Serono Sa adhesion molecules vascular and modulate their function
AU2008201101B2 (en) * 1999-03-11 2011-01-20 Merck Serono Sa Vascular adhesion molecules and modulation of their function
DE19947010A1 (en) * 1999-09-30 2001-04-05 Universitaetsklinikum Freiburg The gene PRV-1 and its use
AU5919101A (en) * 2000-04-28 2001-11-12 Millennium Pharm Inc 25692, a novel human o-methyltransferase family member and uses thereof
GB0110273D0 (en) * 2001-04-26 2001-06-20 Inpharmatica Ltd Novel proteins
JPWO2003097862A1 (en) * 2002-05-17 2005-09-15 協和醗酵工業株式会社 Method for searching a substance having an anti-diabetic action
JP2006501290A (en) * 2002-10-02 2006-01-12 デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング Nucleic acids and proteins having Mipp1 homology involved in the regulation of energy homeostasis
BRPI0619657A2 (en) 2005-11-04 2011-11-08 Genentech Inc Methods of preventing or ameliorating eye disease, use of a complement inhibitor, using a specific siRNA to a protein of the complement system and the use of a nucleic acid encoding an inhibitor of the complement system
EP2068928A2 (en) 2006-09-28 2009-06-17 Merck Serono SA Junctional adhesion molecule-c (jam-c) binding compounds and methods of their use
EP2471818A1 (en) 2006-11-02 2012-07-04 Genentech, Inc. Humanized anti-factor D antibodies and uses thereof
AR066660A1 (en) 2007-05-23 2009-09-02 Genentech Inc Prevention and treatment of eye conditions associated with its complement
CR20170001A (en) 2008-04-28 2017-08-10 Genentech Inc Humanized anti factor d
HUE030092T2 (en) 2008-05-06 2017-05-29 Genentech Inc AFFINITY MATURED CRIg VARIANTS
CN106536561A (en) 2014-05-01 2017-03-22 豪夫迈·罗氏有限公司 Anti-factor D antibody variants and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001970A (en) * 1994-11-07 1999-12-14 Merck & Co., Inc Modified human neuropeptide Y1 Receptors
WO1997025427A1 (en) * 1996-01-12 1997-07-17 Genetics Institute, Inc. Beta-chemokine, h1305 (mcp-2)
JP3646191B2 (en) * 1996-03-19 2005-05-11 大塚製薬株式会社 The human gene
AU746956B2 (en) * 1997-05-06 2002-05-09 Zymogenetics Inc. Novel tumor antigens
AT377025T (en) * 1999-03-08 2007-11-15 Genentech Inc Compositions and methods for diagnosis of tumors
DE19818620A1 (en) * 1998-04-21 1999-10-28 Metagen Gesellschaft Fuer Genomforschung Mbh New polypeptides and their nucleic acids, useful for treatment of bladder tumor and identification of therapeutic agents
EP1090118A2 (en) * 1998-06-26 2001-04-11 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
WO2000004135A2 (en) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Human scad-related molecules, scrm-1 and scrm-2
DE19849044A1 (en) * 1998-10-23 2000-04-27 Univ Ludwigs Albert New polycythemia rubra vera-related polypeptide useful for diagnosis and for developing therapeutic antibodies
EP1131428A2 (en) * 1998-11-19 2001-09-12 Incyte Pharmaceuticals, Inc. Immunoglobulin superfamily proteins

Also Published As

Publication number Publication date
KR20040096629A (en) 2004-11-16
AU2004237842A1 (en) 2005-01-13
AU777006B2 (en) 2004-09-30
WO2000036102A2 (en) 2000-06-22
AU2004237920B2 (en) 2007-08-23
AU2004237920A1 (en) 2005-01-13
AU2004237842B2 (en) 2007-09-20
IL188576D0 (en) 2008-04-13
JP2007075118A (en) 2007-03-29
AU2004237922B2 (en) 2007-09-06
IL188578D0 (en) 2008-04-13
KR100468978B1 (en) 2005-02-02
WO2000036102A3 (en) 2000-11-09
AU2004237919B2 (en) 2007-09-06
IL188580D0 (en) 2008-04-13
JP2004041218A (en) 2004-02-12
IL142794A (en) 2008-03-20
AU2004237922A1 (en) 2005-01-13
AU2004237921B2 (en) 2007-08-23
JP2003521229A (en) 2003-07-15
IL188581D0 (en) 2008-04-13
AU2004237921A1 (en) 2005-01-13
IL200883D0 (en) 2010-05-17
AU2004237919A1 (en) 2005-01-13
JP2007312779A (en) 2007-12-06
EP1141285A2 (en) 2001-10-10
CA2348757A1 (en) 2000-06-22
IL142794D0 (en) 2002-03-10
AU2004237923A1 (en) 2005-01-13
AU2004237923B2 (en) 2007-09-06
AU1932000A (en) 2000-07-03
JP2004041217A (en) 2004-02-12
IL201001D0 (en) 2010-05-17
IL188579D0 (en) 2008-04-13
IL201030D0 (en) 2010-05-17
MXPA01006057A (en) 2003-09-10
IL188577D0 (en) 2008-04-13
KR20010101224A (en) 2001-11-14

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