KR100468977B1 - Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same - Google Patents

Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Info

Publication number
KR100468977B1
KR100468977B1 KR10-2004-7013508A KR20047013508A KR100468977B1 KR 100468977 B1 KR100468977 B1 KR 100468977B1 KR 20047013508 A KR20047013508 A KR 20047013508A KR 100468977 B1 KR100468977 B1 KR 100468977B1
Authority
KR
South Korea
Prior art keywords
polypeptides
present
secreted
same
nucleic acids
Prior art date
Application number
KR10-2004-7013508A
Other languages
Korean (ko)
Other versions
KR20040096629A (en
Inventor
데이비드 보츠타인
루크 데스노이어스
나폴레옹 페라라
셔만 퐁
웨이-퀴앙 가오
오드리 고다드
오스틴 엘. 거니
제임스 판
마가렛 안 로이
티모시 에이. 스튜워트
다니엘 투마스
콜린 케이. 와따나베
윌리엄 아이. 우드
Original Assignee
제넨테크, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/en
Application filed by 제넨테크, 인크. filed Critical 제넨테크, 인크.
Publication of KR20040096629A publication Critical patent/KR20040096629A/en
Application granted granted Critical
Publication of KR100468977B1 publication Critical patent/KR100468977B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
KR10-2004-7013508A 1998-12-16 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same KR100468977B1 (en)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US11314598P 1998-12-16 1998-12-16
US11285198P 1998-12-16 1998-12-16
US60/112,851 1998-12-16
US60/113,145 1998-12-16
US11351198P 1998-12-22 1998-12-22
US60/113,511 1998-12-22
US11556599P 1999-01-12 1999-01-12
US11573399P 1999-01-12 1999-01-12
US11555899P 1999-01-12 1999-01-12
US60/115,733 1999-01-12
US60/115,565 1999-01-12
US60/115,558 1999-01-12
US11934199P 1999-02-09 1999-02-09
US60/119,341 1999-02-09
US11953799P 1999-02-10 1999-02-10
US60/119,537 1999-02-10
US11996599P 1999-02-12 1999-02-12
US60/119,965 1999-02-12
USPCT/US99/12252 1999-06-02
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
PCT/US1999/028634 WO2000036102A2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR10-2001-7007461A Division KR100468978B1 (en) 1998-12-16 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Publications (2)

Publication Number Publication Date
KR20040096629A KR20040096629A (en) 2004-11-16
KR100468977B1 true KR100468977B1 (en) 2005-02-02

Family

ID=27578476

Family Applications (2)

Application Number Title Priority Date Filing Date
KR10-2001-7007461A KR100468978B1 (en) 1998-12-16 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
KR10-2004-7013508A KR100468977B1 (en) 1998-12-16 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR10-2001-7007461A KR100468978B1 (en) 1998-12-16 1999-12-01 Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

Country Status (8)

Country Link
EP (1) EP1141285A2 (en)
JP (5) JP2003521229A (en)
KR (2) KR100468978B1 (en)
AU (7) AU777006B2 (en)
CA (1) CA2348757A1 (en)
IL (11) IL142794A0 (en)
MX (1) MXPA01006057A (en)
WO (1) WO2000036102A2 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US6914130B2 (en) * 1998-06-17 2005-07-05 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
EE05497B1 (en) * 1999-03-11 2011-12-15 Rmf Dictagene S.A. A polypeptide, a soluble CRAM-1 polypeptide, a polynucleotide, and an antibody
AU2008201101B2 (en) * 1999-03-11 2011-01-20 Merck Serono Sa Vascular adhesion molecules and modulation of their function
KR100543857B1 (en) * 1999-09-01 2006-01-23 제넨테크, 인크. Promotion or Inhibition of Angiogenesis and Cardiovascularization
DE19947010A1 (en) * 1999-09-30 2001-04-05 Universitaetsklinikum Freiburg The PRV-1 gene and its use
WO2001083719A2 (en) * 2000-04-28 2001-11-08 Millennium Pharmaceuticals, Inc. 25692, a novel human o-methyltransferase family member and uses thereof
GB0110273D0 (en) * 2001-04-26 2001-06-20 Inpharmatica Ltd Novel proteins
AU2002335054A1 (en) * 2001-12-19 2003-07-09 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US20070191402A1 (en) * 2002-05-17 2007-08-16 Kyowa Hakko Kogyo Co., Ltd. Method of searching substrate having antidiabetic activity
US20050283842A1 (en) * 2002-10-02 2005-12-22 Karsten Eulenberg Mipp1 homologous nucleic acids and proteins involved in the regulation of energy homeostatis
HUE026423T2 (en) 2005-11-04 2016-05-30 Genentech Inc Use of complement pathway inhibitors to treat ocular diseases
US8007797B2 (en) 2006-09-28 2011-08-30 Merck Serono S.A. Junctional adhesion molecule-C (JAM-C) binding compounds and methods of their use
MY183804A (en) 2006-11-02 2021-03-16 Genentech Inc Humanized anti-factor d antibodies
AR066660A1 (en) 2007-05-23 2009-09-02 Genentech Inc PREVENTION AND TREATMENT OF EYE CONDITIONS ASSOCIATED WITH THEIR COMPLEMENT
CR20170001A (en) 2008-04-28 2017-08-10 Genentech Inc ANTI FACTOR D HUMANIZED ANTIBODIES
PE20141549A1 (en) 2008-05-06 2014-10-25 Genentech Inc MATURE CRIG VARIANTS BY AFFINITY
KR20160042438A (en) 2013-08-12 2016-04-19 제넨테크, 인크. Compositions and method for treating complement-associated conditions
TW201623337A (en) 2014-05-01 2016-07-01 建南德克公司 Anti-Factor D antibody variants and uses thereof
EP3368090A1 (en) 2015-10-30 2018-09-05 H. Hoffnabb-La Roche Ag Anti-factor d antibody variant conjugates and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001970A (en) * 1994-11-07 1999-12-14 Merck & Co., Inc Modified human neuropeptide Y1 Receptors
AU1532697A (en) * 1996-01-12 1997-08-01 Genetics Institute Inc. Beta-chemokine, h1305 (mcp-2)
JP3646191B2 (en) * 1996-03-19 2005-05-11 大塚製薬株式会社 Human gene
AU746956B2 (en) * 1997-05-06 2002-05-09 Zymogenetics Inc. Novel tumor antigens
DE19818620A1 (en) * 1998-04-21 1999-10-28 Metagen Gesellschaft Fuer Genomforschung Mbh New polypeptides and their nucleic acids, useful for treatment of bladder tumor and identification of therapeutic agents
EP1090118A2 (en) * 1998-06-26 2001-04-11 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
WO2000004135A2 (en) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Human scad-related molecules, scrm-1 and scrm-2
DE19849044A1 (en) * 1998-10-23 2000-04-27 Univ Ludwigs Albert New polycythemia rubra vera-related polypeptide useful for diagnosis and for developing therapeutic antibodies
WO2000029583A2 (en) * 1998-11-19 2000-05-25 Incyte Pharmaceuticals, Inc. Immunoglobulin superfamily proteins
DK1623989T3 (en) * 1999-03-08 2007-10-15 Genentech Inc Compositions and Methods for Diagnosing Tumors

Also Published As

Publication number Publication date
IL201030A0 (en) 2010-05-17
KR100468978B1 (en) 2005-02-02
EP1141285A2 (en) 2001-10-10
KR20040096629A (en) 2004-11-16
JP2003521229A (en) 2003-07-15
AU1932000A (en) 2000-07-03
IL188579A0 (en) 2008-04-13
AU2004237919B2 (en) 2007-09-06
MXPA01006057A (en) 2003-09-10
KR20010101224A (en) 2001-11-14
IL142794A (en) 2008-03-20
WO2000036102A3 (en) 2000-11-09
JP2007075118A (en) 2007-03-29
AU2004237922A1 (en) 2005-01-13
IL188581A0 (en) 2008-04-13
IL188577A0 (en) 2008-04-13
JP2004041218A (en) 2004-02-12
IL201001A0 (en) 2010-05-17
AU2004237921B2 (en) 2007-08-23
AU777006B2 (en) 2004-09-30
IL188578A0 (en) 2008-04-13
JP2004041217A (en) 2004-02-12
AU2004237922B2 (en) 2007-09-06
AU2004237842A1 (en) 2005-01-13
IL142794A0 (en) 2002-03-10
IL188580A0 (en) 2008-04-13
AU2004237923A1 (en) 2005-01-13
WO2000036102A2 (en) 2000-06-22
IL200883A0 (en) 2010-05-17
AU2004237920B2 (en) 2007-08-23
AU2004237919A1 (en) 2005-01-13
JP2007312779A (en) 2007-12-06
AU2004237923B2 (en) 2007-09-06
AU2004237920A1 (en) 2005-01-13
CA2348757A1 (en) 2000-06-22
AU2004237842B2 (en) 2007-09-20
IL188576A0 (en) 2008-04-13
AU2004237921A1 (en) 2005-01-13

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