KR100421203B1 - Herb medicine composition to be spreaded on sanitary napkin for female - Google Patents

Abstract

The present invention relates to a composition for applying a sanitary napkin for women comprising a gall bladder. Preferably, the present invention relates to a composition for applying a sanitary napkin for women, which further comprises at least one herbal medicine selected from the group consisting of young leaf, red ginseng, yellow white, casualty and alum.

The composition of the present invention suppresses the odor and pruritus generated during women's menstruation when it is applied to a women's sanitary napkin.

Description

Herbal medicine composition to be spreaded on sanitary napkin for female}

The present invention relates to a composition for applying a woman's sanitary napkin, and more particularly, to a composition for applying a woman's sanitary napkin containing a herbal extract component that can be applied to a woman's sanitary napkin in order to remove odor and pruritus generated during women's menstruation.

Women's physiology varies greatly from person to person, but is usually about 100 to 300 cc, of which the blood volume is about 30 to 50 cc, which is mixed with various secretions such as cervical mucus and vulvovaginal glands and fused inner lining. Due to healthy women will have a unique odor during menstruation.

Women's sanitary napkins, which are widely used to date, are simple pads that absorb menstrual blood by varying their size or thickness according to the amount of the menstrual volume, which does not remove the unique odor and pruritus that occur every time menstruation. Women's Sanitary Napkin is covered with vinyl on the outside to prevent moisture from leaking. It's like a bathroom window, so it's easy for mold and bacteria to grow. Menstrual blood odor, which has been plunging for decades from the time menopause until menopause, has been a major contributor to women's activity.

In order to remove the odor and pruritus generated during women's menstruation, the present inventors have padded the cotton pad or paper sheet coated with the drug after many studies and mixed with the drug as the menstrual blood passes and the odor due to the mixed drug effect. The present invention was found to be able to prevent pruritus with.

Accordingly, an object of the present invention is to provide a composition for applying a sanitary napkin for women, which prevents the prism of the skin contact surface and the odor of menstrual blood by using a herbal medicine harmless to the human body.

1 is a cross-sectional view of Application Example 6 as an example of a sanitary napkin for women to which the composition of the present invention is applied. Where a and c are polypropylene membranes, b is the primary pad, d is the absorption matrix, and e is the vinyl cover.

The present invention relates to a composition for applying a sanitary napkin for women comprising a gall bladder.

In detail, the present invention relates to a composition for applying a sanitary napkin for women as a herbal composition that can be applied to a women's sanitary napkin in order to prevent odor generated during menstruation, comprising as a main component of the antimicrobial and antiseptic effect. .

According to the Korean Pharmacopoeia and the traditional Chinese medicine book, the gall bladder contains 70% of tannin and starch, which is a strong astringent drug, which suppresses cell secretion and makes the mucous membrane dry, so it is used for branch, hemostasis, lobulation, oralitis. It is used to apply or apply powder to uterine bleeding and female disease. In addition, the tannins contained in the protein precipitate and coagulate, affecting the nutrition and metabolism of bacteria, which has antibacterial and antiseptic effects, and is used as an antidote for alkaloids.

The composition of the present invention can fully achieve the object of the present invention, even if contained alone in the gall, but more preferably comprises at least one herb selected from the group consisting of apple leaf, red ginseng, yellow white, casualty and alum. , Each component is 25 to 98% by weight, 2 to 30% by weight, 2-30% by weight of red ginseng, 10 to 50% by weight of yellow ginseng, 1 to 20% by weight of yellow and white, Alum is included in the composition of 10 to 40% by weight. Even more preferably it is to include a leaf lobe, yellow white, casualty and alum with the gallant, or to include ginseng, yellow white, casualty and alum with the gallant.

According to the Korean Pharmacopoeia and the traditional Chinese medicine book, Aeopyeop is a herbal medicine that is widely used in gynecological diseases such as menstrual irregularities and crayfish.

In addition, ginseng is used for external use because its taste is too much, it is used in the clinical treatment, such as skin disease, eczema, dermatitis, severe itching due to anti- trichomonas action is mainly used as a poultice therapy or cleaning agent.

In addition, yellow and white bacterium has bactericidal activity against E. coli, typhoid bacteria and cholera bacteria, and has a strong antimicrobial effect against Gram-positive, Gram-negative, and gonococcus bacteria. Berberine, a component of yellowish white, has a strong local astringent action, so it is mainly used for pruritic skin diseases and has the effect of detoxifying heat poisoning at wound sites.

In addition, the casualty is a drug that has a potency of moisturizing and insecticidal, so that it can be used as a cleaning agent by powdering or frying to female pruritus for external use.

In addition, alum has a strong astringent action and antimicrobial and Jiyang effect, removes the discomfort and odor of the inflammatory area to give a refreshing feeling is mainly used for the purpose of the external astringent inflammatory convergence or topical convergence of the skin mucosa.

The above-mentioned herbal medicines, ie, gall bladder, larvae, ginseng, yellowish white, casualty and alum, are all harmless to humans due to their antibacterial and pruritic effects and are often used in clinical practice. Not only does it quickly get rid of pruritus, but also the cold nature of herbal medicines prevents the dampness of the female period during menstruation.

The gall bladder, larvae, red ginseng, yellowish white, filamentous and alum are constituents for the application of women's sanitary napkins as any one selected from powder, extract and leaching solution, respectively. For example, the herbal medicines can be used in combination with the alum leaching filtrate by extracting the active ingredient with water.

The composition of the present invention may be used in the form of a powder, a liquid, a suspension or a gel by containing a pharmaceutically acceptable carrier according to the physicochemical properties of the active ingredient, and the composition of the present invention further contains other additives. can do. The composition of the present invention is particularly preferred in terms of its use in terms of liquid formulation, but may be replaced with other formulations such as powders, sprays, dispersants, gels, etc., if necessary, to form the pads.

Another aspect of the invention is a feminine sanitary napkin to which the composition of the invention is applied. The composition of the present invention may be applied evenly contained throughout the absorption matrix of the sanitary napkin, but at this time, there is a problem that the absorbency of the absorption matrix itself is lowered, so that the upper surface of the matrix, that is, menstrual blood is absorbed into the matrix. It is desirable to apply only to the surface that must pass through to allow physiological blood to be absorbed into the matrix while mixing with the composition of the present invention. As one example, there is a method in which a primary pad obtained by sufficiently applying the composition of the present invention to a cotton cloth or a paper sheet or the like is placed on an existing sanitary napkin.

In another method of applying the composition of the present invention, for example, as a powder as a composition to be uniformly included throughout the sanitary napkin so as not to affect the absorbency of the absorption matrix itself so that menstrual blood can be mixed well with the composition of the present invention. There is a way.

The composition of the present invention can be applied to any method as long as it can mix well with the composition of the present invention so long as the absorbency of the absorption matrix itself is not lowered.

The present invention will be described in more detail with reference to the following examples and experimental examples, but these examples do not limit the scope of the present invention.

Example 1.Preparation of the composition for the application of women's sanitary napkin

After gall bladder 800 g was washed with distilled water, 5000 ml round flask was added and 2000 ml of distilled water was added to the cooler, followed by heat extraction for 2 hours. The extract was filtered through a filter cloth, and the filtrate was concentrated under reduced pressure to obtain 1000 ml of viscous extract.

Example 2 Preparation of Composition for Applying Women's Sanitary Napkin

After gall bladder 600 g was washed with distilled water, and 200 g of alum were added to a 5000 ml round flask, 2000 ml of distilled water was added thereto, and a cooler was attached and heated and extracted for 2 hours. The extract was filtered through a filter cloth, and the filtrate was concentrated under reduced pressure to obtain 1000 ml of viscous extract.

Example 3 Preparation of Composition for Applying Women's Sanitary Napkin

760 g of gall bladder and 40 g of young leaf were washed with distilled water, and 5000 ml of round flasks were added to 2000 ml of distilled water, and a cooler was attached and heated and extracted for 2 hours. The extract was filtered with a filter cloth, and the filtrate was concentrated under reduced pressure to obtain 1000 ml of viscous extract.

Example 4 Preparation of Composition for Applying Women's Sanitary Napkin

After 640 g of gall and 160 g of sulfur white were washed with distilled water, 5000 ml were placed in a round flask, 2000 ml of distilled water was added thereto, and a cooler was attached and heated and extracted for 2 hours. The extract was filtered through a filter cloth, and the filtrate was concentrated under reduced pressure to obtain 1000 ml of viscous extract.

Example 5 Preparation of Composition for Applying Women's Sanitary Napkin

A) Five ginseng 300 g, 100 g of red ginseng, 150 g of yellow white, 50 g of white filament and 100 g of alum were washed with distilled water, and 5000 ml of round flask was added to 2000 ml of distilled water to attach a cooler, followed by heat extraction for 2 hours. The extract was filtered through a filter cloth, and the filtrate was concentrated under reduced pressure to obtain 500 ml of a viscous extract.

B) 100 g of alum was pulverized and warmed in 500 m1 of purified water at a temperature of 75 to 80 ° C. for 2 hours, followed by filtration to mix the viscous extract obtained in a) in a ratio of 1: 1 to prepare a stock solution.

Example 6 Preparation of Composition for Applying Women's Sanitary Napkin

A) 5 g of gallocytes, 10 kg of loaves, 24 kg of yellowish white, 2 kg of casualties and 5 kg of alum and distilled water, and then put 1200 L of purified water together in a double tank for heating using steam at 95 ~ 100 ℃. After heating for 8 hours, the obtained extract was first filtered. The filtrate was transferred to a storage tank of a double tank, and then concentrated under reduced pressure at 60 ° C. through a secondary filtration filter to obtain 40 L of a viscous extract.

B) 5 kg of alum was ground and immersed in 40 L of purified water at a temperature of 75 to 80 ° C. for 2 hours, and then filtered and mixed with the viscous extract obtained in A) in a ratio of 1: 1 to prepare a stock solution.

Application example 1-5. Preparation of Primary Pads

Napkin tissues made of natural pulp of 14 cm width and 5 cm width were immersed in the compositions prepared in Examples 1 to 5, respectively, so that 0.25 g of the composition per dry tissue was uniformly applied as a dry weight. It was.

Application example 6-10. Preparation of Sample Pads

The primary pads prepared in Application Examples 1 to 5 were respectively sandwiched between two layers of 100% polypropylene for diaper production and bonded by instant heat treatment. This was put on a sanitary napkin that was previously used to be in the form as shown in FIG.

Application Example 11. Preparation of Sanitary Napkin

The composition prepared in Example 6 was applied to a nonwoven fabric used in a women's sanitary napkin having a width of 12 cm and a length of 4000 m so that approximately 1 g of the composition per pad of 21 cm width and 9 cm length was uniformly applied as a dry weight. It was. Using this coated nonwoven fabric, a pulp for grinding and an absorbent were put together to produce a sanitary napkin having a width of 21 cm and a length of 9 cm in a factory currently producing women's sanitary napkins.

Experimental Example 1. Toxicity and Side Effects Confirmation Experiment I

The composition prepared in Example 5 was applied to the vaginal openings of four female rabbits three times at 20 minute intervals of 3 ml each, and then the state of the genitals was observed every 6 hours for 6 hours. It was applied and observed.

As a result, no alteration of the genital epidermis or any histological change was observed except vaginal contraction due to application of the composition of the present invention.

Experimental Example 2. Toxicity and Side Effects Confirmation Experiment Ⅱ

The sample pads prepared in Application Example 10 were selected from two members of the present inventors and attached to a sanitary napkin that was used for three months to observe the skin contact surface reaction.

As a result, no changes in skin tissue or local side effects were observed with the use of the pad to which the composition of the present invention was applied. However, after the menstrual blood was absorbed by the pad, the color was changed to black. This phenomenon occurred when the menstrual blood was absorbed and mixed with the drug applied to the pad, and the secretion and the drug were mixed together. It is estimated to be the major mechanism of action for suppressing odor and preventing pruritus.

Experimental Example 3. Efficacy test on odor and pruritus of menstrual blood

Efficacy experiments were carried out using the sample pads prepared in Application Examples 6, 7 and 10 to which the compositions were applied to Examples 1, 2 and 5, respectively. Subjects were all women who agreed with the efficacy test, and had a peculiar feeling of odor. The sample pads consumed an average of 5 sheets per person per day, and divided the pad amount for 6 days. The results were reported at the end of each period. All the participants participated in the experiment reported the result after about a month, and the results were shown in the following Tables 1-6.

Experimental Result of Application Example 6 age Number of subjects Number of subjects who recognized odor suppression effect no effect 30% Suppression 50% Suppression 70% Suppression 90% Suppression 10 2 0 0 One One 0 20's 6 0 One 3 One One 30 spaces 4 0 One One 2 0 40 spaces 2 0 One One 0 0 Total (percentage of total people) 14 0 3 (21.4%) 6 (42.9%) 4 (28.6%) 1 (7.1%)

Experimental Result of Application Example 6 age Number of subjects Number of subjects who recognized pruritus inhibitory effect no effect 30% Suppression 50% Suppression 70% Suppression 90% Suppression 10 2 0 0 2 0 0 20's 6 0 2 4 0 0 30 spaces 4 0 One 2 One 0 40 spaces 2 0 0 2 0 0 Total (percentage of total people) 14 0 3 (21.4%) 10 (71.4%) 1 (7.1%) 0

Experimental Results of Application Example 7 age Number of subjects Number of subjects who recognized odor suppression effect no effect 30% Suppression 50% Suppression 70% Suppression 90% Suppression 10 2 0 0 0 2 0 20's 10 0 One 3 5 One 30 spaces 6 0 0 One 4 One 40 spaces 2 0 0 One One 0 Total (percentage of total people) 20 0 1 (5.0%) 5 (25.0%) 12 (60.0%) 2 (10.0%)

Experimental Results of Application Example 7 age Number of subjects Number of subjects who recognized pruritus inhibitory effect no effect 30% Suppression 50% Suppression 70% Suppression 90% Suppression 10 2 0 0 0 One One 20's 10 0 One 3 6 0 30 spaces 6 0 0 2 2 2 40 spaces 2 0 0 One One 0 Total (percentage of total people) 20 0 1 (5.0%) 6 (30.0%) 10 (50.0%) 3 (15.0%)

Experimental Result of Application Example 10 age Number of subjects Number of subjects who recognized odor suppression effect no effect 30% Suppression 50% Suppression 70% Suppression 90% Suppression 10 One 0 0 One 0 0 20's 8 0 0 One 5 2 30 spaces 2 0 0 0 One One 40 spaces One 0 0 One 0 0 Total (percentage of total people) 12 0 0 3 (25.0%) 6 (50.0%) 3 (25.0%)

Experimental Result of Application Example 10 age Number of subjects Number of subjects who recognized pruritus inhibitory effect no effect 30% Suppression 50% Suppression 70% Suppression 90% Suppression 10 One 0 0 0 0 One 20's 8 0 2 3 2 One 30 spaces 2 0 0 2 0 0 40 spaces One 0 0 0 One 0 Total (percentage of total people) 12 0 2 (16.7%) 5 (41.7%) 3 (25.0%) 2 (16.7%)

Experimental results for the application example 6 to which the composition of Example 1 was applied, 78.6% of all subjects were reported to have an inhibitory effect of 50% or more in both the odor inhibitory effect of Table 1 and the anti-pruritic effect of Table 2.

Experimental results for the application example 7 applying the composition of Example 2, 95.0% of all subjects reported that the odor inhibitory effect of Table 3 and the pruritus inhibitory effect of Table 2 has an inhibitory effect of 50% or more.

In addition, in the experimental results for the application example 10 to which the composition of Example 5 is applied, the odor inhibitory effect of Table 5 reported that all the subjects are odor suppressed by more than 50%, especially seldom felt odor (90% or more odor suppression) Three (25.0%) of the subjects reported the effect. In addition, the antipruritic effect of Table 6 also reported that 83.3% of all subjects had an inhibitory effect of 50% or more.

None of the subjects observed any adverse effects after wearing the pad except for changes in menstrual blood.

Experimental Example 4. Comparative experiment on the effects of physiological blood odor and pruritus

A comparative experiment was conducted on the efficacy of the odor inhibitors of the sanitary napkins to which the composition of the present invention was applied and the two products (products of A company and B company) advertised as odor inhibitors among women's sanitary napkins currently on the market.

As the sanitary napkin to which the composition of the present invention was applied, the female sanitary napkin of Application Example 11 to which the composition of Example 6 was applied was used. Subjects were the total number of women Twenty people were randomly selected and the test method was to set up a survey item about sanitary napkin efficacy, fill out a questionnaire in advance, inform the subjects about the survey item, and divide 10 total sanitary napkins for each person. The survey items consisted of 1) odor suppression effect, 2) anti-pruritic effect, and 3) other opinions after wearing pads.

As a result of this experiment, all respondents showed no or no odor suppression effect (90% of respondents) or insignificant (10% of respondents) of company A and company B, but in contrast, the sanitary napkin to which the composition of the present invention was applied It was confirmed that the odor suppression effect of all respondents had not only a clear odor suppression effect but also a clear anti-pruritic effect.

Experimental Example 5. General Consumer Experiments on the Inhibitory Effects of Menstrual Blood Odor and Pruritus

We randomly selected 60 women from 13 to 49 years of age who live in Seoul, Cheongju, and Daegu, Korea, and wore a sanitary napkin to which the composition of the present invention was applied. As the sanitary napkin to which the composition of the present invention was applied, the female sanitary napkin of Application Example 11 to which the composition of Example 6 was applied was used.

More than 95% of the subjects responded that they had excellent odor suppression (more than 70%) or were effective (more than 25%). The antipruritic effect is almost 100% of women with excellent anti-pruritic effect (67% of all subjects) or effective (except 18% of all subjects), except for 15% of women who did not feel it. Replied.

In addition, as a result of wearing the sanitary napkin to which the composition of the present invention was applied, it was confirmed that the majority of women had no menstrual blood flowing sideways and did not feel the wetness of the skin contact surface. For women wearing the smell as well as the skin was found to have been able to escape the pain of soreness. This is due to the peculiar nature of the herbal medicine of the present invention, namely, moisture and convergence, which is another important advantage in addition to the odor suppression and pruritus suppression effect of the composition of the present invention.

In addition, all the subjects did not observe any adverse effects on the skin contact surface in actual consumer test results.

Women's sanitary napkin coated with the composition of the present invention prepared using a natural drug that is harmless to the human body and exhibits a therapeutic effect, in particular, absorbs the pruritus of the skin contact surface and the odor of menstrual blood generated during menstruation, which conventional sanitary napkins have not solved. At the same time, it prevents the decline of activities caused by odors, expects a more active life of women, and fundamentally liberates women from odors. In addition, the composition of the present invention can be applied directly to the existing non-woven fabrics that are currently used in women's sanitary napkins, so the industrial use value is also very high.

Claims (6)

A composition for applying a female sanitary napkin comprising 25 to 77% by weight, 2 to 30% by weight of young leaves, 10 to 50% by weight of yellow and white, 1 to 20% by weight of casualties, and 10 to 40% by weight of alum. A female sanitary napkin coating composition comprising 25 to 77% by weight, 2 to 30% by weight, red ginseng, 10 to 50% by weight, 1 to 20% by weight of casualties, and 10 to 40% by weight of alum. delete delete delete delete