KR100661014B1 - Herb extract-containing composition for sanitary napkin - Google Patents

Herb extract-containing composition for sanitary napkin Download PDF

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KR100661014B1
KR100661014B1 KR1020060089623A KR20060089623A KR100661014B1 KR 100661014 B1 KR100661014 B1 KR 100661014B1 KR 1020060089623 A KR1020060089623 A KR 1020060089623A KR 20060089623 A KR20060089623 A KR 20060089623A KR 100661014 B1 KR100661014 B1 KR 100661014B1
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extract
sanitary napkin
composition
dried
weight
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KR1020060089623A
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Korean (ko)
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노승욱
우현철
조성희
장태오
안청락
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그린텍이십일 주식회사
안청락
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Priority to CNA2007101370909A priority patent/CN101143228A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera

Abstract

Herb extract containing composition for sanitary napkin is provided to principally inhibit oxidation of menstrual fluid and proliferation of microorganisms on the napkin by obtaining the herb extract from dried Lithospermum erythyrorhizon root, Abies koreana leaves, and other specific herbs through extraction using carbon dioxide and ethanol. The composition comprises: 10-20wt.% of Lithospermum erythrorhizon root extract; 10-20wt.% of Abies koreana leaf extract; 10-20wt.% of Aloe barbadensis extract; 10-20wt.% of Camellia sisnensis extract; 10-20wt.% of Mentha arvensis extract; and 10-20wt.% of Angelica gigas extract. All of the extracts are obtained by applying super-critical extraction method after finely cutting all of the herbs in dried condition. Particularly, the extraction method comprises: cutting each of the dried herbs; feeding the cut materials to a sealed container; introducing carbon dioxide and ethanol into the container at 30 to 50deg.C and under 200 to 400 atmospheric pressure to obtain the extract.

Description

약재 추출물을 함유하는 생리대용 조성물{HERB EXTRACT-CONTAINING COMPOSITION FOR SANITARY NAPKIN}Sanitary napkin composition containing medicinal extract {HERB EXTRACT-CONTAINING COMPOSITION FOR SANITARY NAPKIN}

본 발명은 자초, 구상나무, 알로에, 녹차, 박하, 당귀 등의 약재 추출물을 포함하는, 냄새 억제 및 항균 효과가 우수한 생리대용 조성물에 관한 것이다.The present invention relates to a sanitary napkin composition excellent in odor suppression and antimicrobial effect, including medicinal extracts such as licorice, globose, aloe, green tea, mint, and Angelica.

여성의 생리혈에는 순수한 혈액 외에도 자궁내막 탈락물, 경관점액, 외음부 혼탁물, 질의 냉대하 등 여러 가지 분비물이 혼합되어 있는데, 이 분비물이 몸 밖으로 나오면서 공기와 접촉하여 산화되므로 건강한 여성도 생리시 독특한 냄새가 있게 된다. 기존의 여성용 생리대는 생리량의 많고 적음에 따라 그 크기나 두께를 달리하여 생리혈을 흡수하여 주는 단순기능의 패드이므로, 여성의 생리시에 발생하는 독특한 냄새를 원천적으로 방지하지는 못하였다.In addition to pure blood, women's menstrual blood is mixed with various secretions such as endometrial debris, cervical mucus, vulva mucosa, and cold side of the vagina. Will be. Existing women's sanitary napkin is a pad of a simple function that absorbs menstrual blood by varying its size or thickness according to the large and small amount of menstrual volume, and thus did not prevent the unique smell that occurs during menstruation.

또한, 대부분의 여성용 생리대는 생리혈이 새지 않도록 바깥쪽이 비닐로 덮여있는 밀폐된 구조를 갖기 때문에 미생물의 번식이 매우 용이하다. In addition, most women's sanitary napkins have a closed structure that is covered with vinyl on the outside to prevent leakage of menstrual blood, so microorganisms are very easy to breed.

이에, 생리혈의 산화를 방지하거나 미생물의 번식을 억제하여 질내의 산화적인 조건을 완화함과 동시에 일부 산화되는 부분에 대해서는 냄새를 마스킹하는 효 과를 생리대에 부여하기 위해 당 분야에서 다양한 연구가 수행되어 왔으나, 이제까지 만족할만한 성과를 보지는 못하였다.Accordingly, various studies have been conducted in the art to prevent the oxidation of menstrual blood or to inhibit the growth of microorganisms to alleviate the oxidative conditions in the vagina and to give the sanitary napkin the effect of masking the odor for some oxidized parts. He has come, but has not seen satisfactory results.

따라서, 본 발명의 목적은 생리혈의 산화 및 미생물의 번식을 근본적으로 억제하여 생리시 냄새를 방지할 수 있는 생리대용 조성물을 제공하는 것이다. Accordingly, an object of the present invention is to provide a sanitary napkin composition which can prevent odor during menstruation by fundamentally inhibiting oxidation of menstrual blood and propagation of microorganisms.

상기 목적을 달성하기 위하여 본 발명은, The present invention to achieve the above object,

자초 추출물 10~20 중량%, 구상나뭇잎 추출물 10~20 중량%, 알로에 추출물 10~20 중량%, 녹차 추출물 10~20 중량%, 박하 추출물 10~20 중량% 및 당귀 추출물 10~20 중량%를 포함하는, 생리대용 조성물을 제공한다.It contains 10-20% by weight of Licorice extract, 10-20% by weight of bulbous leaf extract, 10-20% by weight of aloe extract, 10-20% by weight of green tea extract, 10-20% by weight of peppermint extract and 10-20% by weight of Angelica extract. To provide a composition for sanitary napkins.

이하 본 발명을 상세히 설명한다.Hereinafter, the present invention will be described in detail.

본 발명의 생리대용 조성물은 자초, 구상나뭇잎, 알로에, 녹차, 박하 및 당귀 각각의 추출물을 필수성분으로서 포함하는 것을 특징으로 한다. 바람직하게는, 본 발명의 조성물은 자초, 구상나뭇잎, 알로에, 녹차, 박하 및 당귀 각각의 추출물을 동일한 중량비로 포함한다.The sanitary napkin composition of the present invention is characterized in that it comprises as an essential ingredient the extract of each of the herbaceous, spherical leaves, aloe, green tea, mint and Angelica. Preferably, the composition of the present invention comprises the extract of each of the herbaceous, spherical leaves, aloe, green tea, peppermint and Angelica in the same weight ratio.

본 발명에 사용되는 자초(紫草)는 지치과의 여러해살이 풀로서 지치(Lithospermum erythrorhizon)의 뿌리에 해당한다. 자초는 혈열(血熱)로 인한 반 진(斑疹)이 암자색을 보일 때에 유효하며, 토혈, 코피, 소변 출혈에도 빠른 효과를 보이고, 홍역의 예방과 치료에 발병률을 감소시키며, 종기 초기와 피부가 헐어 생긴 발진, 만성궤양, 자궁경부미란, 습진, 불이나 뜨거운 물에 데었을 때 내복하거나 외용한다. 황색포도상구균, 대장균, 인플루엔자균, 이질균, 피부진균에 억제 작용이 있고, 면역 반응에 억제 작용을 나타낸다. 항염증 작용과 가벼운 해열 작용을 보이며, 자궁의 생리 주기 및 발육을 현저하게 억제시키므로 피임 작용을 나타낸다. 상기 자초는 생리혈과 반응시 항균 효과를 나타내어 미생물의 번식을 억제함으로써 산화적인 환경을 억제하여 생리시 냄새의 소지를 없애는 작용을 한다. Licorice (紫草) used in the present invention is a perennial herb of Chiliaceae.Lithospermum erythrorhizonCorresponds to the root. Licorice is effective when hemorrhage due to blood fever is dark purple. It is also effective in bleeding, nosebleed and urine bleeding. When rashes, chronic ulcers, cervical erosions, eczema, or hot or hot water are used, they are internally or externally used. It has an inhibitory effect on Staphylococcus aureus, Escherichia coli, influenza bacteria, dysentery bacteria, and skin fungi, and has an inhibitory effect on immune responses. It has anti-inflammatory and mild antipyretic effects, and because it significantly inhibits the menstrual cycle and development of the uterus, it shows contraception. The porcelain exhibits an antimicrobial effect upon reaction with physiological blood to suppress the propagation of microorganisms, thereby inhibiting the oxidative environment to remove the smell of odor during menstruation.

구상나뭇잎은 소나무과의 늘푸른큰키나무인 구상나무(Abies koreana)의 잎을 말한다. 구상나뭇잎은 연고, 종기, 치통, 통경, 임질 등에 약으로 쓰이며, 항균제, 항곰팡이제로도 사용된 바 있다. 상기 구상나뭇잎은 자체가 항균 효과를 가지고 피톤치드 향을 보유하여 생리혈 특유의 냄새를 효과적으로 마스킹하는 작용을 한다.Globular leaves are Abies, an evergreen and tall tree of the family Pinaceae. speaks leaves of koreana ). Globular leaves are used as ointments, boils, toothaches, pains, gonorrhea, etc., and have been used as antibacterial and antifungal agents. The bulbous leaves themselves have an antimicrobial effect and retain a phytoncide scent to effectively mask the odor peculiar to menstrual blood.

알로에(Aloe Barbadensis)는 백합과의 여러해살이 풀로서, 열이 울결되어 일어나는 변비에 유효하며, 간경(肝經)에 화(火)가 치정(熾盛)하여 어지럼증, 두통, 협통, 변비, 눈의 충혈, 가슴속이 답답하고 편안하지 않아서 팔다리를 가만히 두지 못하는 증상에 탁월하며, 소아의 경련발작에도 유효하다. 소아의 장내 기생충 제거에도 효력을 나타내고, 피부가려움증이나 옴이나 버짐에 쓰이고, 치질로 환부가 붓고 대변에 피가 섞이는 증상에도 용뇌(龍腦)와 혼합해서 환부에 붙인다. 또한, 피부 진균, 건선균의 발육을 억제하며, 항암에 활성 작용을 나타낸다. 상기 알로 에는 생리혈과 반응시 강한 항산화 작용과 항균을 작용을 한다. Aloe Barbadensis ) is a perennial plant of the family Liliaceae, and is effective for constipation caused by a fever of fever, and fires in the cirrhosis are treated with dizziness, headache, narrowing, constipation, redness of the eyes, and heartburn. This frustrating and uncomfortable condition makes it an excellent choice for keeping the limbs still. It is also effective for seizure attacks in children. It is effective for removing intestinal parasites of children, and it is used for itching and scabies and ringworms, and it is mixed with the cerebral brain (龍 腦) to bleed the affected part with hemorrhoids and blood mixed with feces. In addition, it suppresses the development of skin fungi, psoriasis, and has an active effect on cancer. The aloe acts as a strong antioxidant and antibacterial when reacting with menstrual blood.

녹차(Camellia sisnensis)는 주성분인 폴리페놀류의 항산화 작용에 의해 생리혈의 산화를 방지한다.Green tea ( Camellia sisnensis ) prevents the oxidation of menstrual blood by the antioxidant activity of the main polyphenols.

박하(Mentha arvensis)는 진게론, 쇼가올 등의 유효성분을 함유하여 청량하면서도 산뜻한 향을 발산하고 항균해독 작용을 수행하여, 피부에 청량감을 부여하고 마스킹 효과가 탁월하다.Peppermint ( Mentha arvensis ) contains active ingredients such as gingeron and shogaol to emit a refreshing and fresh fragrance and perform antibacterial and detoxification effect, giving the skin a refreshing feeling and excellent masking effect.

당귀(Angelica gigas)는 산형과의 여러해살이 풀로서 주로 뿌리가 사용된다. 당귀는 심혈(心血)과 간혈(肝血)이 부족해서 일어나는 안면창백, 입술과 손톱에 광채가 없고 머리와 눈이 어지러우면서 가슴이 뛰는 증상에 보혈 작용을 하며, 여자의 생리 조절 작용이 뛰어나고 산전 산후 질환에 통용된다. 자궁 흥분과 억제 작용을 조절하고, 단백질 합성을 촉진시키며, 비타민 E 결핍을 방지하므로 유산을 막아주고, 관상 동맥의 혈류량을 촉진시키고 적혈구의 생성을 왕성하게 하며, 항염증, 진통 작용을 나타낸다. 상기 당귀는 예로부터 부인병에 쓰이는 대표적인 약제로서 생리를 조절하고 진통 효과를 갖는다. Angelica gigas ) is a perennial herb that is mainly used as a root. Donggui is a face pale caused by lack of cardiovascular and hepatic blood, lack of gloss on lips and nails, dizziness in head and eyes and heartburn. Commonly used for prenatal postpartum disease Regulates uterine excitability and inhibitory action, promotes protein synthesis, prevents vitamin E deficiency, prevents miscarriage, promotes blood flow in coronary arteries, stimulates red blood cell production, and has anti-inflammatory and analgesic effects. The Angelica is a typical drug used in gynecological diseases since ancient times to regulate physiology and have an analgesic effect.

상술한 이들 약재 추출물은, 건조된 자초, 구상나뭇잎, 알로에, 녹차, 박하 및 당귀를 절단한 후 통상적인 초임계 추출법에 적용함으로써 얻을 수 있다.The above-mentioned medicinal herb extracts can be obtained by cutting dried porridge, spherical leaves, aloe, green tea, peppermint, and Angelica, and then applying them to conventional supercritical extraction methods.

구체적으로는, 건조된 자초, 구상나뭇잎, 알로에, 녹차, 박하 및 당귀를 절단한 후 단독으로 또는 혼합하여 밀폐 용기에 넣고, 200 내지 400기압 및 30 내지 50℃의 조건하에서 용기에 이산화탄소 및 에탄올을 주입하여 추출을 수행함으로써, 목적하는 약재 추출물을 단독으로 또는 혼합된 형태로 얻을 수 있다. 이때, 추출 을 위해 이산화탄소, 에탄올 및 이산화탄소를 순차적으로 주입하는 것이 바람직하다. 목적하는 약재 추출물을 상술한 초임계 추출법으로 얻는 경우, 활성물질의 열적 열화 없이 추출이 가능하며, 산소와 차단되어 산화 없이 추출이 가능하므로 추출물의 항산화성을 높게 유지하는 데에 유리하다.Specifically, the dried licorice, spherical leaves, aloe, green tea, peppermint, and Angelica are cut and put into a closed container alone or mixed, and carbon dioxide and ethanol are added to the container under conditions of 200 to 400 atm and 30 to 50 ° C. By performing extraction by injection, the desired medicinal extract can be obtained alone or in a mixed form. At this time, it is preferable to sequentially inject carbon dioxide, ethanol and carbon dioxide for extraction. When the desired medicinal extract is obtained by the above-described supercritical extraction method, the extract can be extracted without thermal degradation of the active substance, and can be extracted without oxidation because it is blocked with oxygen, which is advantageous for maintaining high antioxidant properties of the extract.

또한, 본 발명의 조성물에 그 약효성분의 물리 화학적 성질에 따라 약제학적으로 허용되는 담체를 함유시켜 산제, 액제, 현탁제 또는 겔제 형태로 만들어 사용할 수 있으며, 필요에 따라, 본 발명의 조성물은 기타의 첨가제를 추가로 함유할 수 있다.In addition, the composition of the present invention may contain a pharmaceutically acceptable carrier according to the physicochemical properties of the active ingredient, and may be used in the form of a powder, a liquid, a suspension, or a gel. It may further contain an additive of.

본 발명에서는, 또다른 실시양태로서 상기 약재 추출물-함유 조성물이 적용된 생리대를 제공한다.In another aspect, the present invention provides a sanitary napkin to which the medicinal extract-containing composition is applied.

본 발명에 따르면, 상기 약재-추출물 함유 조성물을 생리대의 흡수용 매트릭스에 함침 또는 도포한 후 건조하거나, 또는 조성물을 함침 또는 도포한 후 건조한 부직포를 생리대의 흡수용 매트릭스에 밀접하게 위치시킴으로써, 약재-추출물 함유 조성물을 함유하는 흡수용 매트릭스를 포함하거나, 또는 조성물을 함유하는 부직포를 흡수용 매트릭스에 밀접하게 포함하는 본 발명의 생리대를 제조할 수 있다.According to the present invention, the drug-extract containing composition is impregnated or applied to a sanitary napkin absorption matrix and then dried, or the impregnated or applied composition is then dried by placing the dried nonwoven fabric closely on the sanitary napkin absorption matrix. The sanitary napkin of the present invention may be prepared comprising an absorbent matrix containing the extract-containing composition or comprising a nonwoven fabric containing the composition closely in the absorbent matrix.

이외에도, 흡수용 매트릭스 자체의 흡수성을 저하시키지 않는 한, 생리혈과 잘 섞일 수 있도록 본 발명의 조성물을 다양하게 생리대에 적용할 수 있다.In addition, the composition of the present invention may be applied to various sanitary napkins so as to be well mixed with menstrual blood, unless the absorbency of the absorption matrix itself is lowered.

이하, 본 발명을 하기 실시예에 의거하여 좀더 상세하게 설명하고자 한다. 단, 하기 실시예는 본 발명을 예시하기 위한 것일 뿐, 본 발명의 범위가 이들만으로 제한되는 것은 아니다.Hereinafter, the present invention will be described in more detail based on the following examples. However, the following examples are only for illustrating the present invention, and the scope of the present invention is not limited thereto.

실시예Example 1 : 약재 추출물 함유 조성물의 제조 1: Preparation of medicinal extract containing composition

건조된 자초 뿌리, 동결건조된 구상나뭇잎, 동결건조된 알로에 분말, 건조된 녹차의 잎, 건조된 박하 및 건조된 당귀의 뿌리를 100g씩 혼합하여 분쇄하였다. 분쇄된 약재 원료를 1.2리터 초임계 추출조에 넣고 추출조를 밀봉하였다. 고압기체펌프(Haskel Gas Booster, Model No.: AGT-30/75)를 이용하여 이산화탄소를 추출기의 상부로부터 300기압까지 주입하고, 추출기의 내부 온도는 40℃를 유지하였다. 동시에 고압액체펌프(日本精密科學株式會社, Personal Pump, Model No.: NP-D-321)를 이용하여 95% 에탄올 300g을 추출기의 상부로부터 5g/분의 속도로 주입하였다. 추출기 하부에 도출 밸브를 열어 추출물을 받고, 내부압력과 온도가 300기압과 40℃를 유지하도록 고압기체펌프를 조절하였다. 약 1시간 후 에탄올의 주입을 종료하고, 추출기 내부의 에탄올과 추출물을 완전히 추출하기 위해 추가로 30분 동안 이산화탄소만을 투입하여 추출을 수행하였다. 얻은 조추출물을 원심분리하여 상부의 오일층을 제거함으로써 최종 약재 추출물의 혼합물 220g을 얻었다.Dried licorice root, lyophilized spherical leaves, lyophilized aloe powder, dried green tea leaves, dried peppermint and dried Angelica root were mixed and ground by 100 g each. The ground medicinal herb raw materials were placed in a 1.2 liter supercritical extraction tank and the extraction tank was sealed. A high pressure gas pump (Haskel Gas Booster, Model No .: AGT-30 / 75) was used to inject carbon dioxide from the top of the extractor to 300 atm, and the internal temperature of the extractor was maintained at 40 ° C. At the same time, 300 g of 95% ethanol was injected at a rate of 5 g / min from the top of the extractor using a high pressure liquid pump (Personal Pump, Model No .: NP-D-321). The extraction valve was opened at the bottom of the extractor to receive the extract, and the high pressure gas pump was adjusted to maintain the internal pressure and temperature at 300 atm and 40 ° C. After about 1 hour, the injection of ethanol was terminated, and extraction was performed by adding only carbon dioxide for 30 minutes to completely extract the ethanol and the extract inside the extractor. The crude extract obtained was centrifuged to remove an upper oil layer, thereby obtaining 220 g of a mixture of the final herbal extracts.

실시예Example 2 : 약재 추출물-함유 조성물이 적용된 생리대의 제조 2: Preparation of Sanitary Napkin with Medicinal Extract-Containing Composition

<2-1> 가로 120mm, 세로 40mm의 부직포를 상기 실시예 1에서 제조한 약재 추출물에 침지시킨 후 60℃에 방치하여 추출물 중의 에탄올 성분을 제거하였다. 약재 추출물이 함유된 부직포를, 피부 대면 외피, 흡수용 매트릭스 및 방수 외피로 구성된 생리대의 흡수용 매트릭스와 방수 외피의 사이에 위치시켜, 생리대 샘플을 제조하였다.<2-1> The nonwoven fabric having a width of 120 mm and a length of 40 mm was immersed in the medicinal extract prepared in Example 1, and then left at 60 ° C. to remove ethanol from the extract. A sanitary napkin sample was prepared by placing a nonwoven fabric containing the medicinal extract between the absorbent matrix of the sanitary napkin consisting of a skin facing skin, an absorbing matrix and a waterproof skin and a waterproof skin.

<2-2> 생리대의 흡수용 매트릭스를 직접 상기 실시예 1에서 제조한 약재 추출물에 침지시킨 후 60℃에 방치하여 추출물 중의 에탄올 성분을 제거함으로써, 피부 대면 외피, 약재 추출물이 함유된 흡수용 매트릭스 및 방수 외피로 구성된 생리대 샘플을 제조하였다.<2-2> Absorbent matrix containing the skin-facing outer skin, medicinal extract by immersing the absorbent matrix of the sanitary napkin directly to the medicinal extract prepared in Example 1 and left at 60 ℃ to remove the ethanol component of the extract And a sanitary napkin sample composed of a waterproof outer shell.

시험예Test Example 1 : 독성 및 부작용 확인실험 1: Toxicity and Side Effects Confirmation Experiment

상기 실시예 1에서 제조한 조성물을, 성장한 암컷 토끼 4마리의 질구에 3 ml씩 20분 간격으로 5회 도포한 다음 6시간 동안 매 시간마다 성기의 상태를 관찰하였다. 또한, 조성물 6 ml를 5일간 연속해서 도포한 후 성기의 상태를 관찰하였다.The composition prepared in Example 1 was applied to the vaginal balls of four grown female rabbits three times at 20 minute intervals of 3 ml each, and then the state of the genitals was observed every hour for 6 hours. In addition, after 6 ml of the composition was applied continuously for 5 days, the state of the penis was observed.

그 결과, 본 발명의 조성물 도포로 인한 질구의 수축 이외에는 성기 표피의 변질이나 어떠한 조직학적 변화도 관찰되지 않았다.As a result, no alteration of the genital epidermis or any histological changes were observed other than the contraction of the vaginal cord due to the application of the composition of the present invention.

시험예Test Example 2 :  2 : 생리혈의Menstrual 냄새 억제 효과 확인실험 Odor Suppression Effect Confirmation Experiment

13세에서 49세까지의 여성 60명을 대상으로 하여 상기 실시예 2에서 제조한 생리대 샘플을 착용시켜 생리혈의 냄새 억제 효과를 관찰하였다. 본 실험의 대상 여성들은 모두 평소에 생리시 냄새를 느낀 바 있고 특별한 신체 이상은 없는 사람들이었다.60 women aged 13 to 49 years were wearing the sanitary napkin sample prepared in Example 2 to observe the odor suppression effect of menstrual blood. All the women in this experiment had a normal menstrual odor and no physical abnormalities.

전 피험자 중 95% 이상의 피험자가 70% 이상의 냄새 억제 효과 있다고 응답하였다. 또한, 본 발명의 조성물을 적용한 생리대를 착용한 결과, 대다수의 여성 에게서 생리혈이 옆으로 퍼져 흐르는 현상이 없고 피부 접촉면의 습한 기운을 느끼지 못했다는 사실을 확인할 수 있었으며, 특히 병적인 생리(하혈)로 인하여 한달 내내 생리대를 착용하는 여성의 경우 냄새는 물론이고 피부 짓무름의 고통에서 벗어날 수 있었다는 사실을 확인할 수 있었다. 이 또한 본 발명 조성물에 함유된 약재 특유의 기능에 기인한 것으로 판단된다.More than 95% of all the subjects responded that there was more than 70% odor inhibitory effect. In addition, as a result of wearing a sanitary napkin to which the composition of the present invention was applied, it was confirmed that the majority of women did not have menstrual blood flowing sideways and did not feel the wet energy of the skin contact surface. Because of this, women wearing a sanitary napkin were able to confirm that they could get away from the smell of skin and soreness. This is also believed to be attributable to the functions unique to the medicine contained in the composition of the present invention.

이와 같이, 본 발명에 따른 조성물은 생리대에 적용시 생리혈의 산화 및 미생물의 번식을 근본적으로 억제하여 생리시 냄새를 효율적으로 방지할 수 있다.As such, the composition according to the present invention can effectively prevent the oxidization of menstrual blood and propagation of microorganisms when applied to a sanitary napkin to effectively prevent odor during menstruation.

Claims (7)

자초 추출물 10~20 중량%, 구상나뭇잎 추출물 10~20 중량%, 알로에 추출물 10~20 중량%, 녹차 추출물 10~20 중량%, 박하 추출물 10~20 중량% 및 당귀 추출물 10~20 중량%로 이루어진 것을 특징으로 하는 생리대용 조성물.It consists of 10-20% by weight of the extract of Licorice, 10-20% by weight of bulbous leaf extract, 10-20% by weight of aloe extract, 10-20% by weight of green tea extract, 10-20% by weight of peppermint extract and 10-20% by weight of Angelica extract Sanitary napkin composition, characterized in that. 제 1 항에 있어서,The method of claim 1, 자초 추출물, 구상나뭇잎 추출물, 알로에 추출물, 녹차 추출물, 박하 추출물 및 당귀 추출물을 동일한 중량비로 이루어진 것을 특징으로 하는 생리대용 조성물.The composition for sanitary napkin, characterized by the same weight ratio of the extract of Licorice, spherical leaf extract, aloe extract, green tea extract, peppermint extract and Angelica extract. 제 1 항에 있어서,The method of claim 1, 상기 추출물들이, 건조된 자초, 구상나뭇잎, 알로에, 녹차, 박하 및 당귀 각각을 절단한 후 초임계 추출법에 적용하여 얻어진 것임을 특징으로 하는, 생리대용 조성물.The extracts, characterized in that obtained by applying to the supercritical extraction method after cutting each of the dried licorice, spherical leaves, aloe, green tea, peppermint and Angelica. 제 3 항에 있어서,The method of claim 3, wherein 상기 추출물들이, 건조된 자초, 구상나뭇잎, 알로에, 녹차, 박하 및 당귀 각각을 절단한 후 밀폐 용기에 넣고 200 내지 400기압 및 30 내지 50℃의 조건하에서 용기에 이산화탄소 및 에탄올을 주입하여 추출을 수행함으로써 얻어진 것임을 특징 으로 하는, 생리대용 조성물. The extracts were cut into dried licorice, spherical leaves, aloe, green tea, peppermint, and Angelica, and then put into a sealed container and injected with carbon dioxide and ethanol into the container under conditions of 200 to 400 atm and 30 to 50 ° C to perform extraction. Sanitary napkin composition, characterized in that obtained by. 제 1 항의 조성물이 적용된 생리대.Sanitary napkin with the composition of claim 1 applied. 삭제delete 삭제delete
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