KR100190454B1 - 모다피닐의 용도 - Google Patents

모다피닐의 용도 Download PDF

Info

Publication number
KR100190454B1
KR100190454B1 KR1019910009712A KR910009712A KR100190454B1 KR 100190454 B1 KR100190454 B1 KR 100190454B1 KR 1019910009712 A KR1019910009712 A KR 1019910009712A KR 910009712 A KR910009712 A KR 910009712A KR 100190454 B1 KR100190454 B1 KR 100190454B1
Authority
KR
South Korea
Prior art keywords
modafinil
mptp
neuroprotective effect
providing
dopamine
Prior art date
Application number
KR1019910009712A
Other languages
English (en)
Korean (ko)
Other versions
KR920000315A (ko
Inventor
라퐁루이
Original Assignee
파.세 라퐁
라보라뜨와르 엘르 라퐁
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 파.세 라퐁, 라보라뜨와르 엘르 라퐁 filed Critical 파.세 라퐁
Publication of KR920000315A publication Critical patent/KR920000315A/ko
Application granted granted Critical
Publication of KR100190454B1 publication Critical patent/KR100190454B1/ko

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Networks Using Active Elements (AREA)
  • Steroid Compounds (AREA)
KR1019910009712A 1990-06-14 1991-06-13 모다피닐의 용도 KR100190454B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9007442A FR2663225B1 (fr) 1990-06-14 1990-06-14 Nouvelle utilisation du modafinil.
FR90/07442 1990-06-14

Publications (2)

Publication Number Publication Date
KR920000315A KR920000315A (ko) 1992-01-29
KR100190454B1 true KR100190454B1 (ko) 1999-06-01

Family

ID=9397614

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910009712A KR100190454B1 (ko) 1990-06-14 1991-06-13 모다피닐의 용도

Country Status (12)

Country Link
US (1) US5180745A (de)
EP (1) EP0462004B1 (de)
JP (1) JP2531868B2 (de)
KR (1) KR100190454B1 (de)
AT (1) ATE127341T1 (de)
AU (1) AU655769B2 (de)
DE (1) DE69112717T2 (de)
DK (1) DK0462004T3 (de)
FR (1) FR2663225B1 (de)
HK (1) HK1007415A1 (de)
HU (1) HU215590B (de)
TW (1) TW206916B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR950010400B1 (ko) * 1990-08-16 1995-09-16 삼성전자주식회사 김치냉장고의 발효 및 저장제어방법
FR2684875B1 (fr) * 1991-12-13 1995-05-24 Lafon Labor Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique.
US5281607B1 (en) * 1992-10-08 1998-05-19 Univ New York Method of using alpha 2-antagonists for the treatment of neurodegenerative diseases
FR2697162B1 (fr) * 1992-10-23 1995-01-13 Lafon Labor Utilisation du modafinil pour la fabrication d'un médicament pour le traitement de l'incontinence urinaire et des troubles sphinctériens urétro vésicaux.
FR2706767B1 (de) * 1993-06-22 1995-09-08 Lafon Labor
FR2708201B1 (fr) * 1993-06-30 1995-10-20 Lafon Labor Utilisation de dérivés d'acétamide pour la fabrication de médicaments.
US5618845A (en) * 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
KR980010274A (ko) * 1996-07-23 1998-04-30 오상수 열전소자를 이용한 식품저장고
US6346548B1 (en) * 1999-08-16 2002-02-12 Cephalon, Inc. Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue
US6455588B1 (en) 1999-08-20 2002-09-24 Cephalon, Inc. Compositions including modafinil for treatment of eating disorders and for appetite stimulation
KR100350444B1 (ko) * 2000-02-22 2002-08-28 만도공조 주식회사 복합형 김치저장고
US6492396B2 (en) * 2000-05-16 2002-12-10 Cephalon, Inc. Substituted thioacetamides
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
PL215226B1 (pl) * 2000-10-11 2013-11-29 Cephalon Kompozycja farmaceutyczna zawierajaca zwiazek modafinilu, sposób jej wytwarzania oraz jej zastosowanie
US6489363B2 (en) 2000-10-11 2002-12-03 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
KR100911779B1 (ko) * 2001-05-25 2009-08-12 세파론, 인코포레이티드 모다피닐을 포함하는 고형 제약 제제
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040048931A1 (en) 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US6992219B2 (en) 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
IL153098A0 (en) * 2002-11-26 2003-06-24 Chemagis Ltd Pharmaceutical compositions containing modafinil
FR2849029B1 (fr) * 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
EP1603867A2 (de) * 2003-02-24 2005-12-14 Mallinckrodt Inc. Verfahren zur herstellung von benzhydrylthioacetamid
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
AR045423A1 (es) * 2003-05-13 2005-10-26 Cephalon Inc Combinaciones de analiticos y antidepresivos
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
EP1586560A1 (de) * 2004-04-13 2005-10-19 Cephalon, Inc. Thio-substituierte Arylmethansulfinyl-Derivate
US7314875B2 (en) * 2004-04-13 2008-01-01 Cephalon, Inc. Tricyclic aromatic and bis-phenyl sulfinyl derivatives
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
US7423176B2 (en) * 2004-04-13 2008-09-09 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
US7119214B2 (en) * 2004-04-13 2006-10-10 Cephalon France Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US7297817B2 (en) * 2004-04-13 2007-11-20 Cephalon France Thio-substituted arylmethanesulfinyl derivatives
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
US20080181966A1 (en) * 2006-10-18 2008-07-31 Cephalon, Inc. Modafinil pharmaceutical compositions
CN101641090B (zh) * 2006-12-19 2012-12-05 亚勒斯有限公司 莫达非尼在制备治疗多动腿综合征的药物中的应用
US20090325999A1 (en) * 2008-06-27 2009-12-31 Jie Du Personalized pharmaceutical kits, packaging and compositions for the treatment of allergic conditions
EP2238973A1 (de) 2009-04-07 2010-10-13 Cephalon France Lyophilisierte Präparate von Proteasominhibitoren
EP3040078B1 (de) 2013-08-30 2021-02-24 Green Cross Wellbeing Corporation Zusammensetzung zur vorbeugung und behandlung von krebsbedingter fatigue mit verarbeitetem ginseng-pulver oder verarbeitetem ginseng-extrakt mit erhöhtem gehalt des bestandteils ginsenosid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520812A (en) * 1975-10-02 1978-08-09 Lafon Labor Benzhydrylsulphinyl derivatives
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
DE69112717T2 (de) 1996-04-11
HK1007415A1 (en) 1999-04-09
AU7843691A (en) 1991-12-19
FR2663225A1 (fr) 1991-12-20
JPH04230214A (ja) 1992-08-19
FR2663225B1 (fr) 1994-11-04
DK0462004T3 (da) 1995-10-16
US5180745A (en) 1993-01-19
HUT57984A (en) 1992-01-28
KR920000315A (ko) 1992-01-29
EP0462004A3 (en) 1992-01-22
EP0462004A2 (de) 1991-12-18
DE69112717D1 (de) 1995-10-12
EP0462004B1 (de) 1995-09-06
TW206916B (de) 1993-06-01
AU655769B2 (en) 1995-01-12
JP2531868B2 (ja) 1996-09-04
ATE127341T1 (de) 1995-09-15
HU215590B (hu) 1999-01-28
HU911968D0 (en) 1991-12-30

Similar Documents

Publication Publication Date Title
KR100190454B1 (ko) 모다피닐의 용도
Argov et al. Drug-induced peripheral neuropathies.
WO2001009118A3 (en) Dithiolthione compounds for the treatment of neurological disorders and for memory enhancement
ES2131525T3 (es) Usos terapeuticos de la melanina.
TW200607510A (en) Use of optically pure (s.s)-reboxetine in the manufacture of a medicament for the treatment or prevention of fibromyalgia or another somatoform disorder
MX348062B (es) Mutantes que degradan proteoglicanos para tratamiento del snc.
ATE100322T1 (de) Verwendung von uridin zur behandlung nervoeser stoerungen.
JPH05504546A (ja) 痛みのある疾患又はアレルギー性疾患の治療用組成物及び治療法
DE60218193D1 (de) Verwendung von 2-oxo-1-pyrrolidin-derivaten zur herstellung eines arzneimittels zur behandlung von dyskinesia
Date et al. Exogenous GM1 gangliosides induce partial recovery of the nigrostriatal dopaminergic system in MPTP-treated young mice but not in aging mice
Tzankova et al. Cytisine—from ethomedical use to the development as a natural alternative for smoking cessation
DE60128911T2 (de) Verwendung von l-threo-methylphenidat zur herstellung eines medikamentes zur behandlung von psychischen erkrankungen
Essman et al. Serotonin in learning and memory
Bassi et al. Dopamine receptors and sleep induction in man.
Andrews et al. Effect of the (+)-and (-)-enantiomers of sulpiride on ADTN-induced hyperactivity in the rat [proceedings]
DE68928169T2 (de) Zusammensetzung zur Behandlung von degenerativen Krankheiten des Nervensystems
Date et al. Stereotaxic injection of GD1a ganglioside induces limited recovery of striatal dopaminergic system in MPTP‐treated aging mice
Kawashima et al. Amygdaloid catecholaminergic mechanisms involved in suppressive effects of electroconvulsive shock on duration of immobility in rat forced to swim
JPH06509073A (ja) 光学的に純粋なs(−)オンダンセトロンを使用する嘔吐、吐き気および他の障害の治療のための方法および組成物
EP1632235A3 (de) Verwendung von hochselektiven Norepinephrin-Aufnahme-Inhibitoren zur Behandlung von mentalen Erkrankungen
Jeon et al. A synergy effect of combination of acupoints in cocaine take
HK1042238A1 (en) Treatment of symptoms of parkinson's disease with an agent comprising a dopaminergic substance and a local anaesthetic of the anilide group
Roufs L-tyrosine in the treatment of narcolepsy
Aguilera et al. Tetanus intoxication causes an increment of serotonin in the central nervous system
Irvine Refining the benefits of nicotine

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20110112

Year of fee payment: 13

EXPY Expiration of term