KR0166084B1 - N-시클로알킬알킬아민, 그의 제조 방법, 약제로서 그의 용도 및 그의 합성 중간체 - Google Patents

N-시클로알킬알킬아민, 그의 제조 방법, 약제로서 그의 용도 및 그의 합성 중간체 Download PDF

Info

Publication number
KR0166084B1
KR0166084B1 KR1019910003016A KR910003016A KR0166084B1 KR 0166084 B1 KR0166084 B1 KR 0166084B1 KR 1019910003016 A KR1019910003016 A KR 1019910003016A KR 910003016 A KR910003016 A KR 910003016A KR 0166084 B1 KR0166084 B1 KR 0166084B1
Authority
KR
South Korea
Prior art keywords
group
general formula
compound
formula
thienyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019910003016A
Other languages
English (en)
Korean (ko)
Other versions
KR910021396A (ko
Inventor
오바르 길베르
깔베 알렝
데포 쟝-끌로드
구레 끌로드-쟝
그루엘 아그네
허즈페쓰 제임스
쟈꼬벨리 앙리
쥬니엥 쟝-루이스
빠스꼬 사비에르
로망 프랑수와
링 유앙
Original Assignee
쟝-프랑수와 꼴라
주베이날 에스. 에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/484,403 external-priority patent/US5034419A/en
Application filed by 쟝-프랑수와 꼴라, 주베이날 에스. 에이. filed Critical 쟝-프랑수와 꼴라
Publication of KR910021396A publication Critical patent/KR910021396A/ko
Application granted granted Critical
Publication of KR0166084B1 publication Critical patent/KR0166084B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019910003016A 1990-02-26 1991-02-25 N-시클로알킬알킬아민, 그의 제조 방법, 약제로서 그의 용도 및 그의 합성 중간체 Expired - Fee Related KR0166084B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US484,403 1983-04-12
US07/484,403 US5034419A (en) 1988-09-01 1990-02-26 N-cycloalkylalkylamines, process for their preparation, their use as medicament and their synthesis intermediates
FR9002494 1990-02-28
FR9002494A FR2658822A1 (fr) 1990-02-28 1990-02-28 N-cycloalkylalkylamines, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.

Publications (2)

Publication Number Publication Date
KR910021396A KR910021396A (ko) 1991-12-20
KR0166084B1 true KR0166084B1 (ko) 1999-01-15

Family

ID=9394221

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910003016A Expired - Fee Related KR0166084B1 (ko) 1990-02-26 1991-02-25 N-시클로알킬알킬아민, 그의 제조 방법, 약제로서 그의 용도 및 그의 합성 중간체

Country Status (2)

Country Link
KR (1) KR0166084B1 (enrdf_load_stackoverflow)
FR (1) FR2658822A1 (enrdf_load_stackoverflow)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86740A (en) * 1987-06-30 1992-11-15 Tanabe Seiyaku Co Thiphene derivatives,their preparation and pharmaceutical compositions containing them
JPS6416778A (en) * 1987-07-09 1989-01-20 Tanabe Seiyaku Co Thiophene derivative

Also Published As

Publication number Publication date
KR910021396A (ko) 1991-12-20
FR2658822B1 (enrdf_load_stackoverflow) 1994-08-19
FR2658822A1 (fr) 1991-08-30

Similar Documents

Publication Publication Date Title
US5010090A (en) N-(butenyl substituted) azaheterocyclic carboxylic acids
EP2094706B1 (fr) Derives de 2,5-dfflydro-3h-pyrazolo[4,3-c]pyridazin-3-one substitues, leur preparation et leur utilisation comme ligands des recepteurs cb1 des cannabinoides
EP1641758B1 (fr) Derives de diphenylpyridine, leur preparation et leur application therapeutique
WO2006087476A2 (fr) Derives de 1,5-diarylpyrrole, leur preparation et leur application en therapeutique
US5034419A (en) N-cycloalkylalkylamines, process for their preparation, their use as medicament and their synthesis intermediates
JP3594310B2 (ja) シグマ受容体のリガンドである 新規２−アリールアルケニルアザシクロアルカン誘導体、その製造方法及び治療薬としてのその使用
EP2094656B1 (fr) Derives de pyrrole, leur preparation et leur utilisation en therapeutique.
US4857543A (en) Thiophene derivative and process for preparing the same
EP1899298A2 (fr) Derives de 4,5-diarylpyrrole, leur preparation et leur application en therapeutique
AU2001289937B2 (en) Substituted 1-aminobutan-3-ol derivatives
JP5147398B2 (ja) 置換アクリルアミド誘導体及びそれを含む医薬組成物
US5387590A (en) Benzazabicyclic carbamates as novel cholinesterase inhibitors
KR0166084B1 (ko) N-시클로알킬알킬아민, 그의 제조 방법, 약제로서 그의 용도 및 그의 합성 중간체
JPS6216947B2 (enrdf_load_stackoverflow)
CA2037114C (en) N-cycloalkylalkylamines, their process of preparation, their use as medication and their synthetic intermediates
US4946862A (en) Thiophene derivative and process for preparing the same
EP1878723A1 (fr) Dérivés de N-[(1,5-diphényl-1H-pyrazol-3-yl)méthyl]sulfonamide antagonistes des récepteurs CB1 des cannabinoïdes
JPH0665163A (ja) 置換エチルアミン類、その製造法、薬剤としての使用ならびに合成中間体
US5594002A (en) Benzazabicyclic carbamates as novel cholinesterase inhibitors
HU217873B (hu) N-cikloalkil-amin-származékok, valamint hatóanyagként e vegyületeket tartalmazó gyógyászati készítmények
GB1573396A (en) 3-thienyl-3-methyl-4-pentl-2-pyridyl ketone
HK1029042A (en) Ligands for sigma receptors and their therapeutical applications

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 20020726

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20030923

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20030923

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000