KE3877A - Benzothienylallylamines processes for their production and their use as pharmaceuticals - Google Patents

Benzothienylallylamines processes for their production and their use as pharmaceuticals

Info

Publication number
KE3877A
KE3877A KE3877A KE387789A KE3877A KE 3877 A KE3877 A KE 3877A KE 3877 A KE3877 A KE 3877A KE 387789 A KE387789 A KE 387789A KE 3877 A KE3877 A KE 3877A
Authority
KE
Kenya
Prior art keywords
benzothienylallylamines
pharmaceuticals
processes
production
benzothienylallylamines processes
Prior art date
Application number
KE3877A
Other languages
English (en)
Inventor
Stutz Anton
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of KE3877A publication Critical patent/KE3877A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Refuge Islands, Traffic Blockers, Or Guard Fence (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KE3877A 1982-02-03 1989-04-26 Benzothienylallylamines processes for their production and their use as pharmaceuticals KE3877A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH656/82A CH653028A5 (de) 1982-02-03 1982-02-03 Benzthiophenallylamin-verbindungen und verfahren zu ihrer herstellung.

Publications (1)

Publication Number Publication Date
KE3877A true KE3877A (en) 1989-07-21

Family

ID=4192086

Family Applications (1)

Application Number Title Priority Date Filing Date
KE3877A KE3877A (en) 1982-02-03 1989-04-26 Benzothienylallylamines processes for their production and their use as pharmaceuticals

Country Status (28)

Country Link
US (2) US4474141A (it)
JP (1) JPS58146580A (it)
AT (1) AT391865B (it)
AU (1) AU569838B2 (it)
BE (1) BE895751A (it)
CA (1) CA1193271A (it)
CH (1) CH653028A5 (it)
CY (1) CY1485A (it)
DE (1) DE3302814A1 (it)
DK (1) DK160043C (it)
ES (1) ES8403473A1 (it)
FI (1) FI80689C (it)
FR (1) FR2520741B1 (it)
GB (1) GB2116171B (it)
HK (1) HK47789A (it)
HU (1) HU190886B (it)
IE (1) IE55073B1 (it)
IL (1) IL67813A0 (it)
IT (1) IT1197565B (it)
KE (1) KE3877A (it)
MY (1) MY8700167A (it)
NL (1) NL8300350A (it)
NZ (1) NZ203144A (it)
PH (1) PH22625A (it)
PT (1) PT76175B (it)
SE (1) SE455095B (it)
SG (1) SG16289G (it)
ZA (1) ZA83733B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH672311A5 (it) * 1985-09-14 1989-11-15 Sandoz Ag
US5068359A (en) * 1989-06-20 1991-11-26 Ciba-Geigy Corporation Microbicidal compositions
AU634871B2 (en) * 1990-03-20 1993-03-04 Banyu Pharmaceutical Co., Ltd. Substituted amine derivatives having anti-hyperlipemia activity
FR2695930B1 (fr) * 1992-09-22 1994-12-23 Sanofi Elf Dérivé du 2-éthyl benzo[b]thiophène, son procédé de préparation et son utilisation comme intermédiaire de synthèse.
JP4759500B2 (ja) * 2001-02-22 2011-08-31 帝人株式会社 ベンゾ［ｂ］チオフェン誘導体、およびその製造方法
TW200734321A (en) * 2005-10-27 2007-09-16 Teijin Pharma Ltd Benzo [b] thiophen derivatives and a process for producing benzo [b] thiophen derivatives
CN102898314B (zh) * 2012-11-13 2014-09-03 山东铂源药业有限公司 一种盐酸特比萘芬的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1250019B (it) * 1963-07-19
CH442353A (de) * 1964-04-16 1967-08-31 Sandoz Ag Verfahren zur Herstellung von neuen Benzothiophen-Derivaten
US3930537A (en) * 1974-05-06 1976-01-06 The United States Of America As Represented By The United States Energy Research And Development Administration Heat exchanger
DE2862103D1 (en) * 1977-08-19 1982-11-18 Sandoz Ag Propenyl amines, processes for their production and pharmaceutical compositions containing them
DE3069633D1 (en) * 1979-08-22 1984-12-20 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals

Also Published As

Publication number Publication date
FI830297L (fi) 1983-08-04
DE3302814C2 (it) 1992-06-25
US4474141A (en) 1984-10-02
DK40883A (da) 1983-08-04
SE8300535L (sv) 1983-08-04
HU190886B (en) 1986-12-28
FI830297A0 (fi) 1983-01-27
ZA83733B (en) 1984-09-26
CA1193271A (en) 1985-09-10
AU569838B2 (en) 1988-02-25
GB2116171B (en) 1986-04-03
MY8700167A (en) 1987-12-31
US4737516A (en) 1988-04-12
SE455095B (sv) 1988-06-20
BE895751A (fr) 1983-08-01
PH22625A (en) 1988-10-28
AU1089783A (en) 1983-08-11
CH653028A5 (de) 1985-12-13
IE830202L (en) 1983-08-03
SE8300535D0 (sv) 1983-02-01
PT76175A (en) 1983-03-01
GB8302573D0 (en) 1983-03-02
IE55073B1 (en) 1990-05-23
FR2520741B1 (fr) 1986-03-21
FI80689C (fi) 1990-07-10
FI80689B (fi) 1990-03-30
DK160043B (da) 1991-01-21
SG16289G (en) 1989-07-07
ATA34983A (de) 1990-06-15
NL8300350A (nl) 1983-09-01
IL67813A0 (en) 1983-06-15
NZ203144A (en) 1985-12-13
AT391865B (de) 1990-12-10
HK47789A (en) 1989-06-23
CY1485A (en) 1989-12-08
ES519477A0 (es) 1984-03-16
PT76175B (en) 1986-01-15
IT8347666A0 (it) 1983-02-03
FR2520741A1 (fr) 1983-08-05
DK160043C (da) 1991-06-17
DK40883D0 (da) 1983-02-01
GB2116171A (en) 1983-09-21
DE3302814A1 (de) 1983-08-11
IT1197565B (it) 1988-12-06
ES8403473A1 (es) 1984-03-16
JPS58146580A (ja) 1983-09-01
JPH0446275B2 (it) 1992-07-29

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