JPWO2024004661A1 - - Google Patents

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Publication number
JPWO2024004661A1
JPWO2024004661A1 JP2024530676A JP2024530676A JPWO2024004661A1 JP WO2024004661 A1 JPWO2024004661 A1 JP WO2024004661A1 JP 2024530676 A JP2024530676 A JP 2024530676A JP 2024530676 A JP2024530676 A JP 2024530676A JP WO2024004661 A1 JPWO2024004661 A1 JP WO2024004661A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2024530676A
Other languages
Japanese (ja)
Other versions
JP7846763B2 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of JPWO2024004661A1 publication Critical patent/JPWO2024004661A1/ja
Application granted granted Critical
Publication of JP7846763B2 publication Critical patent/JP7846763B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01084—Nitrile hydratase (4.2.1.84)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2024530676A 2022-06-30 2023-06-14 変異型ニトリルヒドラターゼ、該変異型ニトリルヒドラターゼをコードする核酸、該核酸を含むベクター及び形質転換体、該変異型ニトリルヒドラターゼの製造方法、並びにアミド化合物の製造方法 Active JP7846763B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022106069 2022-06-30
JP2022106069 2022-06-30
PCT/JP2023/022166 WO2024004661A1 (ja) 2022-06-30 2023-06-14 変異型ニトリルヒドラターゼ、該変異型ニトリルヒドラターゼをコードする核酸、該核酸を含むベクター及び形質転換体、該変異型ニトリルヒドラターゼの製造方法、並びにアミド化合物の製造方法

Publications (2)

Publication Number Publication Date
JPWO2024004661A1 true JPWO2024004661A1 (https=) 2024-01-04
JP7846763B2 JP7846763B2 (ja) 2026-04-15

Family

ID=89382091

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024530676A Active JP7846763B2 (ja) 2022-06-30 2023-06-14 変異型ニトリルヒドラターゼ、該変異型ニトリルヒドラターゼをコードする核酸、該核酸を含むベクター及び形質転換体、該変異型ニトリルヒドラターゼの製造方法、並びにアミド化合物の製造方法

Country Status (6)

Country Link
EP (1) EP4549571A1 (https=)
JP (1) JP7846763B2 (https=)
KR (1) KR20250011936A (https=)
CN (1) CN119343452A (https=)
TW (1) TW202409063A (https=)
WO (1) WO2024004661A1 (https=)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004194588A (ja) * 2002-12-19 2004-07-15 Mitsui Chemicals Inc 新規なニトリルヒドラターゼ
WO2007043466A1 (ja) * 2005-10-07 2007-04-19 Mitsui Chemicals, Inc. アミド化合物の製造方法
JP2008506397A (ja) * 2004-07-19 2008-03-06 チバ　スペシャルティ　ケミカルズ　ウォーター　トリートメント　リミテッド モノマー及びそのポリマーを調製する方法
WO2010055666A1 (ja) * 2008-11-14 2010-05-20 三井化学株式会社 ニトリルヒドラターゼ変異体
WO2018124247A1 (ja) * 2016-12-28 2018-07-05 三井化学株式会社 変異型ニトリルヒドラターゼ、該変異型ニトリルヒドラターゼをコードする核酸、該核酸を含む発現ベクター及び形質転換体、該変異型ニトリルヒドラターゼの製造方法、並びにアミド化合物の製造方法
JP2019176835A (ja) * 2018-03-30 2019-10-17 三井化学株式会社 アミド化合物の製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3408737B2 (ja) 1998-03-16 2003-05-19 三井化学株式会社 ニトリルヒドラターゼの活性化に関与するタンパク質及びそれをコードする遺伝子
JP2022106069A (ja) 2021-01-06 2022-07-19 Ａｓｓｅｓｔ株式会社 動物意思判別プログラム

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004194588A (ja) * 2002-12-19 2004-07-15 Mitsui Chemicals Inc 新規なニトリルヒドラターゼ
JP2008506397A (ja) * 2004-07-19 2008-03-06 チバ　スペシャルティ　ケミカルズ　ウォーター　トリートメント　リミテッド モノマー及びそのポリマーを調製する方法
WO2007043466A1 (ja) * 2005-10-07 2007-04-19 Mitsui Chemicals, Inc. アミド化合物の製造方法
WO2010055666A1 (ja) * 2008-11-14 2010-05-20 三井化学株式会社 ニトリルヒドラターゼ変異体
WO2018124247A1 (ja) * 2016-12-28 2018-07-05 三井化学株式会社 変異型ニトリルヒドラターゼ、該変異型ニトリルヒドラターゼをコードする核酸、該核酸を含む発現ベクター及び形質転換体、該変異型ニトリルヒドラターゼの製造方法、並びにアミド化合物の製造方法
JP2019176835A (ja) * 2018-03-30 2019-10-17 三井化学株式会社 アミド化合物の製造方法

Also Published As

Publication number Publication date
CN119343452A (zh) 2025-01-21
KR20250011936A (ko) 2025-01-22
JP7846763B2 (ja) 2026-04-15
EP4549571A1 (en) 2025-05-07
WO2024004661A1 (ja) 2024-01-04
TW202409063A (zh) 2024-03-01

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