JPWO2023282269A1 - - Google Patents

Info

Publication number
JPWO2023282269A1
JPWO2023282269A1 JP2023533152A JP2023533152A JPWO2023282269A1 JP WO2023282269 A1 JPWO2023282269 A1 JP WO2023282269A1 JP 2023533152 A JP2023533152 A JP 2023533152A JP 2023533152 A JP2023533152 A JP 2023533152A JP WO2023282269 A1 JPWO2023282269 A1 JP WO2023282269A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023533152A
Other languages
Japanese (ja)
Other versions
JPWO2023282269A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2023282269A1 publication Critical patent/JPWO2023282269A1/ja
Publication of JPWO2023282269A5 publication Critical patent/JPWO2023282269A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D341/00Heterocyclic compounds containing rings having three or more sulfur atoms as the only ring hetero atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2023533152A 2021-07-08 2022-07-05 Pending JPWO2023282269A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021113378 2021-07-08
PCT/JP2022/026755 WO2023282269A1 (ja) 2021-07-08 2022-07-05 パーキンソン病の予防又は治療薬

Publications (2)

Publication Number Publication Date
JPWO2023282269A1 true JPWO2023282269A1 (https=) 2023-01-12
JPWO2023282269A5 JPWO2023282269A5 (https=) 2024-04-04

Family

ID=84801700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023533152A Pending JPWO2023282269A1 (https=) 2021-07-08 2022-07-05

Country Status (5)

Country Link
US (1) US20240293359A1 (https=)
EP (1) EP4342464A4 (https=)
JP (1) JPWO2023282269A1 (https=)
CN (1) CN117320709A (https=)
WO (1) WO2023282269A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12552764B2 (en) 2020-08-27 2026-02-17 Kyowa Pharma Chemical Co., Ltd. Trisulfide compound and clathrate thereof
TW202321270A (zh) * 2021-09-09 2023-06-01 國立大學法人九州大學 使用三硫化合物之防止肝細胞增殖因子中之酪胺酸殘基之硝基化的方法
WO2025070464A1 (ja) * 2023-09-28 2025-04-03 協和ファーマケミカル株式会社 トリスルフィド化合物を含有する医薬組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668117A (en) * 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
WO2006043532A1 (ja) * 2004-10-19 2006-04-27 Ono Pharmaceutical Co., Ltd. パーキンソン病治療剤
WO2017177262A1 (en) * 2016-04-11 2017-10-19 University Of Canberra Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier
EP3560947B1 (en) 2016-12-20 2022-08-24 Kyowa Hakko Bio Co., Ltd. Crystal of glutathione trisulfide dihydrate and method for producing same
CN111699023A (zh) * 2017-12-07 2020-09-22 C·杜克 线粒体靶向、mptp调节以及线粒体反应物质和/或线粒体反应脂质物质的还原
CN111320603A (zh) * 2018-12-13 2020-06-23 江苏同禾药业有限公司 一种硫辛酸工艺杂质的制备方法
JP2022074166A (ja) * 2019-01-30 2022-05-18 協和発酵バイオ株式会社 ポリスルフィド化合物を含有する組成物
JP2022166333A (ja) * 2019-09-18 2022-11-02 国立大学法人 熊本大学 活性イオウ分子種生体内濃度上昇剤
CN115087635B (zh) 2020-03-31 2024-04-12 协和医药化工股份有限公司 三硫化物化合物或硒代三硫化物化合物的制造方法
JP7842033B2 (ja) * 2020-05-12 2026-04-07 ザ ジェネラル ホスピタル コーポレイション 神経保護におけるグルタチオントリスルフィド(gsssg)
US12552764B2 (en) 2020-08-27 2026-02-17 Kyowa Pharma Chemical Co., Ltd. Trisulfide compound and clathrate thereof
JP7650279B2 (ja) 2020-08-27 2025-03-24 協和ファーマケミカル株式会社 トリスルフィド化合物

Also Published As

Publication number Publication date
EP4342464A4 (en) 2025-06-04
US20240293359A1 (en) 2024-09-05
CN117320709A (zh) 2023-12-29
WO2023282269A1 (ja) 2023-01-12
EP4342464A1 (en) 2024-03-27

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Legal Events

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A521 Request for written amendment filed

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Effective date: 20231122

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Effective date: 20250501