JPWO2023168367A5 - - Google Patents
Info
- Publication number
- JPWO2023168367A5 JPWO2023168367A5 JP2024551891A JP2024551891A JPWO2023168367A5 JP WO2023168367 A5 JPWO2023168367 A5 JP WO2023168367A5 JP 2024551891 A JP2024551891 A JP 2024551891A JP 2024551891 A JP2024551891 A JP 2024551891A JP WO2023168367 A5 JPWO2023168367 A5 JP WO2023168367A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- ring
- compound
- independently
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263315968P | 2022-03-02 | 2022-03-02 | |
| US63/315,968 | 2022-03-02 | ||
| US202363478467P | 2023-01-04 | 2023-01-04 | |
| US63/478,467 | 2023-01-04 | ||
| PCT/US2023/063623 WO2023168367A1 (en) | 2022-03-02 | 2023-03-02 | QUINOLINE cGAS ANTAGONIST COMPOUNDS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025507820A JP2025507820A (ja) | 2025-03-21 |
| JPWO2023168367A5 true JPWO2023168367A5 (https=) | 2026-03-10 |
| JP2025507820A5 JP2025507820A5 (https=) | 2026-03-10 |
Family
ID=85781707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024551891A Pending JP2025507820A (ja) | 2022-03-02 | 2023-03-02 | キノリンｃＧａｓアンタゴニスト化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US12281078B2 (https=) |
| EP (1) | EP4486734A1 (https=) |
| JP (1) | JP2025507820A (https=) |
| KR (1) | KR20250004639A (https=) |
| CN (1) | CN119137112A (https=) |
| AU (1) | AU2023228915A1 (https=) |
| CA (1) | CA3253386A1 (https=) |
| IL (1) | IL315346A (https=) |
| MX (1) | MX2024010674A (https=) |
| TW (1) | TW202342021A (https=) |
| WO (1) | WO2023168367A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230062845A (ko) | 2020-09-03 | 2023-05-09 | 이뮨센서 테라퓨틱스, 인코포레이티드 | 퀴놀린 cgas 길항제 화합물 |
| CN119137112A (zh) | 2022-03-02 | 2024-12-13 | 免疫传感器治疗股份有限公司 | 喹啉cGAS拮抗剂化合物 |
| WO2026050765A1 (en) | 2024-08-30 | 2026-03-05 | Immunesensor Therapeutics, Inc. | Solid forms and salts of a quinoline cgas antagonist compound |
| WO2026057087A1 (zh) * | 2024-09-14 | 2026-03-19 | 杭州英创医药科技有限公司 | 作为cGAS抑制剂的化合物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3542785A (en) * | 1967-05-15 | 1970-11-24 | Ciba Geigy Corp | 2-hydroxy-4-aryl-quinolines |
| US3668207A (en) * | 1970-01-22 | 1972-06-06 | Ciba Geigy Corp | 2-amino-4-aryl-quinolines |
| WO2004002960A1 (en) * | 2002-06-27 | 2004-01-08 | Schering Aktiengesellschaft | Substituted quinoline ccr5 receptor antagonists |
| AU2008303602A1 (en) | 2007-09-27 | 2009-04-02 | F. Hoffmann-La Roche Ag | Quinoline derivatives as 5HT5A receptor antagonists |
| JP2019501904A (ja) * | 2015-12-14 | 2019-01-24 | ファンダシオン パラ ラ インベスティガシオン メディカ アプリカダＦｕｎｄａｃｉｏｎ Ｐａｒａ Ｌａ Ｉｎｖｅｓｔｉｇａｓｉｏｎ Ｍｅｄｉｃａ Ａｐｌｉｃａｄａ | Ｄｎａメチルトランスフェラーゼの阻害剤としての２，４，６，７−四置換キノリン化合物 |
| CN109111426B (zh) | 2017-06-23 | 2021-12-14 | 中国科学院上海药物研究所 | 一类稠合双环杂芳基或芳基化合物，及其用途 |
| IL302338B2 (en) | 2017-09-08 | 2024-10-01 | Univ Leland Stanford Junior | Enpp1 inhibitors and their use for the treatment of cancer |
| WO2019241787A1 (en) | 2018-06-15 | 2019-12-19 | The Regents Of The University Of Colorado A Body Corporate | Novel cyclic gmp-amp synthase (cgas) inhibitors and their method of use |
| US12064433B2 (en) | 2018-07-27 | 2024-08-20 | Arcus Biosciences, Inc. | Pyridone A2R antagonists |
| EP3620164A1 (en) * | 2018-09-05 | 2020-03-11 | Genoscience Pharma SAS | Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases |
| WO2020142735A1 (en) | 2019-01-04 | 2020-07-09 | BellBrook Labs | Inhibitors of cgas activity as therapeutic agents |
| EP4076667A1 (en) | 2019-12-20 | 2022-10-26 | Erasca, Inc. | Tricyclic pyridones and pyrimidones |
| CN115209883B (zh) | 2020-01-20 | 2025-05-20 | 新月生物科学 | 新型细胞代谢调节化合物及其用途 |
| JP2023532998A (ja) | 2020-07-06 | 2023-08-01 | クレセンタ バイオサイエンシズ | 新規細胞代謝調節化合物およびそのウイルス性疾患の治療のための使用 |
| KR20230062845A (ko) | 2020-09-03 | 2023-05-09 | 이뮨센서 테라퓨틱스, 인코포레이티드 | 퀴놀린 cgas 길항제 화합물 |
| CN119137112A (zh) | 2022-03-02 | 2024-12-13 | 免疫传感器治疗股份有限公司 | 喹啉cGAS拮抗剂化合物 |
-
2023
- 2023-03-02 CN CN202380037098.5A patent/CN119137112A/zh active Pending
- 2023-03-02 EP EP23714185.8A patent/EP4486734A1/en active Pending
- 2023-03-02 KR KR1020247032755A patent/KR20250004639A/ko active Pending
- 2023-03-02 WO PCT/US2023/063623 patent/WO2023168367A1/en not_active Ceased
- 2023-03-02 IL IL315346A patent/IL315346A/en unknown
- 2023-03-02 JP JP2024551891A patent/JP2025507820A/ja active Pending
- 2023-03-02 AU AU2023228915A patent/AU2023228915A1/en active Pending
- 2023-03-02 CA CA3253386A patent/CA3253386A1/en active Pending
- 2023-03-02 TW TW112107684A patent/TW202342021A/zh unknown
- 2023-03-02 US US18/177,732 patent/US12281078B2/en active Active
- 2023-07-17 US US18/353,718 patent/US12091387B2/en active Active
-
2024
- 2024-08-30 MX MX2024010674A patent/MX2024010674A/es unknown
-
2025
- 2025-02-27 US US19/066,046 patent/US20260042737A1/en active Pending
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